IL155506A0 - Process for folding chemically synthesized polypeptides - Google Patents

Process for folding chemically synthesized polypeptides

Info

Publication number: IL155506A0
Authority: IL; Israel
Prior art keywords: chemically synthesized; folding; synthesized polypeptides; cysteine; reducing agent
Prior art date: 2000-11-27

Application number

IL15550601A

Other languages

English (en)

Original Assignee

Rmf Dictagene Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-27

Filing date

2001-11-27

Publication date

2003-11-23

2001-11-27 Application filed by Rmf Dictagene Sa filed Critical Rmf Dictagene Sa

2003-11-23 Publication of IL155506A0 publication Critical patent/IL155506A0/xx

Links

229920001184 polypeptide Polymers 0.000 title abstract 3
102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 3
239000003638 chemical reducing agent Substances 0.000 abstract 2
GFQRKHUHTJYDPB-LURJTMIESA-O CCCC[S+]=C([C@H](CS)N)O Chemical group CCCC[S+]=C([C@H](CS)N)O GFQRKHUHTJYDPB-LURJTMIESA-O 0.000 abstract 1
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
235000018417 cysteine Nutrition 0.000 abstract 1
235000018102 proteins Nutrition 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Analytical Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

IL15550601A 2000-11-27 2001-11-27 Process for folding chemically synthesized polypeptides IL155506A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00204207		2000-11-27
PCT/EP2001/014163 WO2002050099A2 (en)	2000-11-27	2001-11-27	Process for folding chemically synthesized polypeptides

Publications (1)

Publication Number	Publication Date
IL155506A0 true IL155506A0 (en)	2003-11-23

Family

ID=8172340

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL15550601A IL155506A0 (en)	2000-11-27	2001-11-27	Process for folding chemically synthesized polypeptides

Country Status (22)

Country	Link
US (2)	US20020082384A1 (es)
EP (2)	EP1337549B1 (es)
JP (1)	JP2004516300A (es)
KR (1)	KR20030081315A (es)
CN (2)	CN1249078C (es)
AT (1)	ATE322501T1 (es)
AU (2)	AU2960302A (es)
BR (1)	BR0113091A (es)
CA (1)	CA2416054A1 (es)
CU (1)	CU23034A3 (es)
DE (1)	DE60118598T2 (es)
DK (1)	DK1337549T3 (es)
ES (1)	ES2261509T4 (es)
HU (1)	HUP0302395A3 (es)
IL (1)	IL155506A0 (es)
MX (1)	MXPA03003576A (es)
NO (1)	NO20032356L (es)
NZ (1)	NZ523679A (es)
PL (1)	PL364932A1 (es)
RU (1)	RU2275377C2 (es)
WO (1)	WO2002050099A2 (es)
ZA (1)	ZA200300642B (es)

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US7091310B2 (en) *	2002-09-13	2006-08-15	Chemokine Therapeutics Corporation	Chemokine analogs for the treatment of human disease
US7214660B2 (en)	2001-10-10	2007-05-08	Neose Technologies, Inc.	Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7173003B2 (en)	2001-10-10	2007-02-06	Neose Technologies, Inc.	Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
EP2055189A1 (en)	2003-04-09	2009-05-06	Neose Technologies, Inc.	Glycopegylation methods and proteins/peptides produced by the methods
WO2005012484A2 (en)	2003-07-25	2005-02-10	Neose Technologies, Inc.	Antibody-toxin conjugates
US20080305992A1 (en)	2003-11-24	2008-12-11	Neose Technologies, Inc.	Glycopegylated erythropoietin
WO2006045603A1 (en) *	2004-10-26	2006-05-04	Lonza Ag	S-alkyl-sulphenyl protection groups in solid-phase synthesis
US20080176790A1 (en)	2004-10-29	2008-07-24	Defrees Shawn	Remodeling and Glycopegylation of Fibroblast Growth Factor (Fgf)
US9029331B2 (en)	2005-01-10	2015-05-12	Novo Nordisk A/S	Glycopegylated granulocyte colony stimulating factor
US20070154992A1 (en)	2005-04-08	2007-07-05	Neose Technologies, Inc.	Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
EP1893632B1 (en) *	2005-06-17	2015-08-12	Novo Nordisk Health Care AG	Selective reduction and derivatization of engineered factor vii proteins comprising at least one non-native cysteine
US20070105755A1 (en)	2005-10-26	2007-05-10	Neose Technologies, Inc.	One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en)	2005-11-03	2007-05-18	Neose Technologies, Inc.	Nucleotide sugar purification using membranes
JP2009520739A (ja) *	2005-12-23	2009-05-28	アプラゲンゲーエムベーハー	ジスルフィド架橋の形成方法
US8022181B2 (en) *	2006-05-03	2011-09-20	Mallinckrodt Llc	Composition and method for the release of protected peptides from a resin
ES2516694T3 (es)	2006-07-21	2014-10-31	Ratiopharm Gmbh	Glicosilación de péptidos a través de secuencias de glicosilación con unión en O
US8969532B2 (en)	2006-10-03	2015-03-03	Novo Nordisk A/S	Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
KR20100016160A (ko)	2007-04-03	2010-02-12	바이오제너릭스 에이지	글리코페길화 ｇ―ｃｓｆ를 이용하는 치료 방법
WO2008154639A2 (en)	2007-06-12	2008-12-18	Neose Technologies, Inc.	Improved process for the production of nucleotide sugars
US20100203001A1 (en) *	2007-07-11	2010-08-12	Aplagen Gmbh	Process for forming disulfide bridges
KR101582841B1 (ko)	2008-02-27	2016-01-11	노보 노르디스크 에이/에스	콘쥬게이트된 인자 ｖｉｉｉ 분자
CN104844693B (zh) *	2015-06-10	2018-08-03	成都圣诺生物科技股份有限公司	一种合成利那洛肽的方法
WO2019149918A1 (en)	2018-02-02	2019-08-08	Novo Nordisk A/S	Drug injection device with deflectable transducer
CN111100188A (zh) *	2018-10-25	2020-05-05	成都医学院	一种制备蜘蛛抗菌肽的方法
CN109593119A (zh) *	2019-01-27	2019-04-09	上海丽珠制药有限公司	一种[2-d-组氨酸]-醋酸亮丙瑞林的制备方法
JP7453745B2 (ja) *	2019-03-28	2024-03-21	株式会社ヤクルト本社	毒性タンパク質の活性を阻害するペプチドのスクリーニング方法及び毒性タンパク質の製造方法
CN110845595A (zh) *	2019-11-14	2020-02-28	连云港职业技术学院	一种固相合成5-tmara标记的铁调素-25的方法
IL296767A (en) *	2020-03-30	2022-11-01	Ablynx Nv	A method for the production and purification of single variable multivalent immunoglobulin sites

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2923787A1 (de) *	1979-06-12	1980-12-18	Max Planck Gesellschaft	Verfahren zur selektiven bildung von disulfidbruecken in polypeptiden und die dabei erhaltenen produkte als wirkstoffe enthaltende arzneimittel
DE3236849A1 (de) *	1982-10-05	1984-04-05	Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen	Neue thiohydrazin-1,2-dicarbonsaeure-derivate, verfahren zu ihrer herstellung und ihre verwendung
IL96682A0 (en) *	1989-12-15	1991-09-16	Amgen Inc	Production of biologically active platelet-derived growth factor from high expression host cell systems
RU2148586C1 (ru) *	1991-03-15	2000-05-10	Эмджен Инк.	Ковалентное модифицирование полипептидов полиэтиленгликолями
CA2072249C (en) *	1991-06-28	2003-06-17	Saiko Hosokawa	Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
CN1105029A (zh) *	1993-05-24	1995-07-12	花王株式会社	制备溶解蛋白质的方法
US5663304A (en) *	1993-08-20	1997-09-02	Genentech, Inc.	Refolding of misfolded insulin-like growth factor-I
DE4431317A1 (de) *	1994-09-02	1996-03-07	Biotechnolog Forschung Gmbh	Schutz- bzw. Ankergruppen und deren Verwendung

2001
- 2001-11-27 KR KR10-2003-7004957A patent/KR20030081315A/ko not_active Ceased
- 2001-11-27 JP JP2002551992A patent/JP2004516300A/ja active Pending
- 2001-11-27 DK DK01990489T patent/DK1337549T3/da active
- 2001-11-27 ES ES01990489T patent/ES2261509T4/es not_active Expired - Lifetime
- 2001-11-27 IL IL15550601A patent/IL155506A0/xx unknown
- 2001-11-27 CU CU20030094A patent/CU23034A3/es unknown
- 2001-11-27 NZ NZ523679A patent/NZ523679A/en unknown
- 2001-11-27 CN CNB018147968A patent/CN1249078C/zh not_active Expired - Fee Related
- 2001-11-27 HU HU0302395A patent/HUP0302395A3/hu unknown
- 2001-11-27 MX MXPA03003576A patent/MXPA03003576A/es active IP Right Grant
- 2001-11-27 WO PCT/EP2001/014163 patent/WO2002050099A2/en not_active Ceased
- 2001-11-27 PL PL01364932A patent/PL364932A1/xx not_active Application Discontinuation
- 2001-11-27 AU AU2960302A patent/AU2960302A/xx active Pending
- 2001-11-27 CA CA002416054A patent/CA2416054A1/en not_active Abandoned
- 2001-11-27 US US09/995,335 patent/US20020082384A1/en not_active Abandoned
- 2001-11-27 EP EP01990489A patent/EP1337549B1/en not_active Expired - Lifetime
- 2001-11-27 RU RU2003119075/04A patent/RU2275377C2/ru not_active IP Right Cessation
- 2001-11-27 CN CNA2006100047520A patent/CN1830999A/zh active Pending
- 2001-11-27 DE DE60118598T patent/DE60118598T2/de not_active Expired - Fee Related
- 2001-11-27 BR BR0113091-9A patent/BR0113091A/pt not_active IP Right Cessation
- 2001-11-27 AU AU2002229603A patent/AU2002229603B2/en not_active Expired - Fee Related
- 2001-11-27 EP EP06075237A patent/EP1679318A1/en not_active Withdrawn
- 2001-11-27 AT AT01990489T patent/ATE322501T1/de not_active IP Right Cessation
2003
- 2003-01-23 ZA ZA200300642A patent/ZA200300642B/en unknown
- 2003-05-26 NO NO20032356A patent/NO20032356L/no unknown
2005
- 2005-05-19 US US11/132,987 patent/US20050239162A1/en not_active Abandoned

Also Published As

Publication number	Publication date
HUP0302395A2 (hu)	2003-10-28
BR0113091A (pt)	2003-07-08
CN1449406A (zh)	2003-10-15
US20050239162A1 (en)	2005-10-27
DK1337549T3 (da)	2006-07-31
CN1249078C (zh)	2006-04-05
AU2960302A (en)	2002-07-01
NZ523679A (en)	2005-10-28
US20020082384A1 (en)	2002-06-27
JP2004516300A (ja)	2004-06-03
HUP0302395A3 (en)	2007-05-02
DE60118598D1 (de)	2006-05-18
WO2002050099A2 (en)	2002-06-27
ATE322501T1 (de)	2006-04-15
WO2002050099A3 (en)	2002-09-19
ES2261509T3 (es)	2006-11-16
KR20030081315A (ko)	2003-10-17
DE60118598T2 (de)	2007-02-15
CN1830999A (zh)	2006-09-13
NO20032356D0 (no)	2003-05-26
MXPA03003576A (es)	2003-10-14
EP1337549B1 (en)	2006-04-05
EP1337549A2 (en)	2003-08-27
AU2002229603B2 (en)	2007-11-08
CA2416054A1 (en)	2002-06-27
CU23034A3 (es)	2005-03-22
EP1679318A1 (en)	2006-07-12
PL364932A1 (en)	2004-12-27
ES2261509T4 (es)	2008-02-16
ZA200300642B (en)	2004-07-16
RU2275377C2 (ru)	2006-04-27
NO20032356L (no)	2003-05-26

Publication	Publication Date	Title
AU2960302A (en)	2002-07-01	Process for folding chemically synthesized polypeptides
ATE293159T1 (de)	2005-04-15	Stabilisierendes verdünnungsmittel für polypeptide und antigene
PL357638A1 (en)	2004-07-26	Use of acid-stable subtilisin proteases in animal feed
IL161016A (en)	2014-07-31	Polypeptides capable of ang-2 binding
ATE274884T1 (de)	2004-09-15	Künstliches fingergelenk
DK1629849T3 (da)	2013-08-12	Farmaceutiske sammensætninger indeholdende exendiner og deres agonister
IL138608A0 (en)	2001-10-31	Antibody variants and fragments thereof
DE19781680T1 (de)	1999-04-15	Verfahren zur Herabsetzung des Sauerstoffgehaltes in Ventilmetall-Materialien
WO2002002143A3 (en)	2002-07-18	Enhancement of antibody-cytokine fusion protein mediated immune responses by combined treatment with immunocytokine uptake enhancing agents
MY134077A (en)	2007-11-30	Cross-linking of starch
AU2002217505A1 (en)	2003-01-23	Process for producing recombinant protein and fused protein
MXPA03010684A (es)	2005-11-04	Peptidos y el uso de los mismos para oscurecer la piel.
AU2003211379A1 (en)	2004-03-19	Process for producing collagen treated with cysteine protease and collagen treated with cysteine protease
HUP0100974A3 (en)	2002-06-28	Integrated additive composition, process for its preparation and its use
HUT64369A (en)	1993-12-28	Collagen binding protein and method for producing it
GB0022995D0 (en)	2000-11-01	Polynucleotide
MXPA04002103A (es)	2004-06-07	Una proteina de union a caspasa-8, su preparacion y uso.
ATE113986T1 (de)	1994-11-15	Verfahren zur herstellung von aprotinin und aprotinin-homologen in hefe.
DE60220658D1 (de)	2007-07-26	Verfahren zur produktion von 2,6-dihalogenopurinen
ZA200107919B (en)	2003-03-26	Site-specific isotopically-labeled proteins, amino acids, and biochemical precursors therefor.
DE69736325D1 (de)	2006-08-24	Cr1 fragmente und deren verwendung
WO2001078765A3 (de)	2002-04-11	Prophylaxe und therapie von diabetes mellitus 1 mit hilfe proteolytischer enzyme
ES1043476U (es)	1999-12-16	Chapa perfeccinada
MXPA04004303A (es)	2004-08-11	Composicion farmaceutica que comprende polipeptidos del factor vii y polipeptidos pai-1.
ES1054532U (es)	2003-08-01	Dispositivo para endulzar y al mismo tiempo remover una bebida.