IL156352A0 - Sodium channel moddulators derived from 2-piperidylimidazoles - Google Patents

Sodium channel moddulators derived from 2-piperidylimidazoles

Info

Publication number
IL156352A0
IL156352A0 IL15635201A IL15635201A IL156352A0 IL 156352 A0 IL156352 A0 IL 156352A0 IL 15635201 A IL15635201 A IL 15635201A IL 15635201 A IL15635201 A IL 15635201A IL 156352 A0 IL156352 A0 IL 156352A0
Authority
IL
Israel
Prior art keywords
piperidylimidazoles
moddulators
derived
sodium channel
sodium
Prior art date
Application number
IL15635201A
Other languages
English (en)
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of IL156352A0 publication Critical patent/IL156352A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL15635201A 2000-12-28 2001-12-27 Sodium channel moddulators derived from 2-piperidylimidazoles IL156352A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0017149A FR2818978B1 (fr) 2000-12-28 2000-12-28 Modulateurs de canaux sodiques derives de 2-piperidylimidazoles
PCT/FR2001/004209 WO2002053559A1 (fr) 2000-12-28 2001-12-27 Modulateurs de canaux sodiques derives de 2-piperidylimidazoles

Publications (1)

Publication Number Publication Date
IL156352A0 true IL156352A0 (en) 2004-01-04

Family

ID=8858291

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15635201A IL156352A0 (en) 2000-12-28 2001-12-27 Sodium channel moddulators derived from 2-piperidylimidazoles

Country Status (24)

Country Link
US (1) US20040077640A1 (cs)
EP (1) EP1349850B1 (cs)
JP (1) JP2004517121A (cs)
KR (1) KR100892656B1 (cs)
CN (1) CN1214025C (cs)
AR (1) AR035613A1 (cs)
AT (1) ATE304005T1 (cs)
AU (1) AU2002228128B8 (cs)
BR (1) BR0116581A (cs)
CA (1) CA2432959A1 (cs)
CZ (1) CZ20032053A3 (cs)
DE (1) DE60113297T2 (cs)
DK (1) DK1349850T3 (cs)
ES (1) ES2249488T3 (cs)
FR (1) FR2818978B1 (cs)
HU (1) HUP0600032A2 (cs)
IL (1) IL156352A0 (cs)
MX (1) MXPA03005914A (cs)
NO (1) NO20032904D0 (cs)
NZ (1) NZ526394A (cs)
PL (1) PL363640A1 (cs)
RU (1) RU2275369C2 (cs)
WO (1) WO2002053559A1 (cs)
ZA (1) ZA200305005B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008001596A (ja) * 2004-09-03 2008-01-10 Astellas Pharma Inc ナトリウムチャネル阻害剤
EP1963280B1 (en) * 2005-12-22 2015-10-28 Newron Pharmaceuticals S.p.A. 2-phenylethylamino derivatives as calcium and/or sodium channel modulators
CN101454299A (zh) 2006-03-27 2009-06-10 东丽株式会社 酰脲衍生物及其医药用途
DE102007047243A1 (de) 2007-09-25 2009-04-02 Karl Storz Gmbh & Co. Kg Bipolares medizinisches Instrument
CN101970432B (zh) * 2008-01-25 2014-05-28 杜邦公司 杀真菌杂环化合物
WO2025122832A1 (en) * 2023-12-07 2025-06-12 Genep Inc. Imidazole compounds and their use as sodium channel inhibitors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0633882A1 (en) * 1992-04-01 1995-01-18 The University Of Toledo 4- 4'-piperidinyl or 3'-pirrolidinyl] substituted imidazoles as h3-receptor antagonists and therapeutic uses thereof
US5296609A (en) * 1993-04-09 1994-03-22 Syntex Pharmaceuticals, Ltd. Process for the preparation of 1,2,4-substituted imidazoles and related aminoalkylimidazole derivatives
EP0793653A1 (en) * 1994-11-23 1997-09-10 Neurogen Corporation Certain 4-aminomethyl-2-substituted imidazole derivatives and 2-aminomethyl-4-substituted imidazole derivatives; new classes of dopamine receptor subtype specific ligands
KR19990064117A (ko) * 1995-10-06 1999-07-26 폴락 돈나 엘. 항암 활성과 사이토킨 억제 활성을 갖는 치환된 이미다졸
ES2239357T3 (es) * 1996-06-10 2005-09-16 MERCK & CO., INC. Imidazoles sustituidos que tienen actividad inhibidora de citoquinas.
HUP0302962A2 (hu) * 1998-06-12 2003-12-29 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. Béta-karbolinszármazékok, ezeket a vegyületeket tartalmazó gyógyászati készítmények és a vegyületek alkalmazása
TW502019B (en) * 1999-03-26 2002-09-11 Cocensys Inc Aryl substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles, and the use thereof
US6297256B1 (en) * 1999-06-15 2001-10-02 Neurogen Corporation Aryl and heteroaryl substituted pyridino derivatives GABA brain receptor ligands
TWI283577B (en) * 1999-10-11 2007-07-11 Sod Conseils Rech Applic Pharmaceutical composition of imidazole derivatives acting as modulators of sodium channels and the use thereof
EP1237875B1 (en) * 1999-12-16 2005-08-31 Schering Corporation Substituted imidazole neuropeptide y y5 receptor antagonists

Also Published As

Publication number Publication date
WO2002053559A1 (fr) 2002-07-11
AU2002228128B8 (en) 2007-01-04
KR20030070592A (ko) 2003-08-30
AU2002228128A1 (en) 2002-07-16
FR2818978B1 (fr) 2003-02-28
CN1483029A (zh) 2004-03-17
HK1059784A1 (en) 2004-07-16
NO20032904L (no) 2003-06-24
CZ20032053A3 (en) 2004-04-14
PL363640A1 (en) 2004-11-29
EP1349850B1 (fr) 2005-09-07
EP1349850A1 (fr) 2003-10-08
FR2818978A1 (fr) 2002-07-05
AU2002228128B2 (en) 2006-08-03
RU2275369C2 (ru) 2006-04-27
CA2432959A1 (fr) 2002-07-11
ES2249488T3 (es) 2006-04-01
ZA200305005B (en) 2004-06-28
ATE304005T1 (de) 2005-09-15
JP2004517121A (ja) 2004-06-10
HUP0600032A2 (en) 2006-06-28
AR035613A1 (es) 2004-06-16
KR100892656B1 (ko) 2009-04-15
NO20032904D0 (no) 2003-06-24
BR0116581A (pt) 2004-01-06
NZ526394A (en) 2004-12-24
DK1349850T3 (da) 2006-01-23
US20040077640A1 (en) 2004-04-22
MXPA03005914A (es) 2003-09-10
CN1214025C (zh) 2005-08-10
RU2003123119A (ru) 2005-01-10
DE60113297D1 (de) 2005-10-13
DE60113297T2 (de) 2006-07-13

Similar Documents

Publication Publication Date Title
AU6227101A (en) Substituted iminoazines
GB0025695D0 (en) Seal
GB0020532D0 (en) Channel member
AU5825501A (en) Substituted benzoylcyclohexenones
PL358119A1 (en) Substituted phenyluracils
AU1480002A (en) An improved seal
IL156352A0 (en) Sodium channel moddulators derived from 2-piperidylimidazoles
GB0028849D0 (en) Improved keysheath
AU2360402A (en) Substituted phenyluracils
GB0012559D0 (en) Seal
GB0028423D0 (en) Eductional aid
GB0004254D0 (en) Improved capodastro
EP1347049A4 (en) NEW POTASSIUM CHANNEL
EP1347050A4 (en) NEW POTASSIUM CHANNELS
GB0028494D0 (en) Tassel-making aid
GB2364426B (en) Improved capodastro
GB0027048D0 (en) Shield
GB0015191D0 (en) Advance arrangement
AU142595S (en) Channel member
TW414240U (en) Tent-roof improvement
AU150772S (en) Channel
TW465873U (en) Improved weight-loading block
GB0116730D0 (en) Sodium channel inhibitors
AU140459S (en) Channel
GB0022048D0 (en) Instant seal