IL157303A0 - Quinoline, isoquinoline and phthalazine derivatives as antagonists of the gonadotropin-releasing hormone - Google Patents

Quinoline, isoquinoline and phthalazine derivatives as antagonists of the gonadotropin-releasing hormone

Info

Publication number
IL157303A0
IL157303A0 IL15730302A IL15730302A IL157303A0 IL 157303 A0 IL157303 A0 IL 157303A0 IL 15730302 A IL15730302 A IL 15730302A IL 15730302 A IL15730302 A IL 15730302A IL 157303 A0 IL157303 A0 IL 157303A0
Authority
IL
Israel
Prior art keywords
gonadotropin
isoquinoline
quinoline
antagonists
releasing hormone
Prior art date
Application number
IL15730302A
Other languages
English (en)
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2001108271 external-priority patent/DE10108271A1/de
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of IL157303A0 publication Critical patent/IL157303A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL15730302A 2001-02-21 2002-02-21 Quinoline, isoquinoline and phthalazine derivatives as antagonists of the gonadotropin-releasing hormone IL157303A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2001108271 DE10108271A1 (de) 2001-02-21 2001-02-21 Chinolin-, Isochinolin- und Phthalazinderivate als Antagonisten des Gonadotropin freisetzenden Hormons
US27491401P 2001-03-13 2001-03-13
PCT/EP2002/001882 WO2002066437A1 (de) 2001-02-21 2002-02-21 Chinolin-, isochinolin- und phthalazinderivate als antagonisten des gonadotropin freisetzenden hormons

Publications (1)

Publication Number Publication Date
IL157303A0 true IL157303A0 (en) 2004-02-19

Family

ID=26008581

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15730302A IL157303A0 (en) 2001-02-21 2002-02-21 Quinoline, isoquinoline and phthalazine derivatives as antagonists of the gonadotropin-releasing hormone

Country Status (17)

Country Link
EP (1) EP1362034A1 (pt)
JP (1) JP2004528298A (pt)
CN (1) CN1496354A (pt)
AU (1) AU2002247737B2 (pt)
BG (1) BG108165A (pt)
BR (1) BR0207451A (pt)
CA (1) CA2438709A1 (pt)
CZ (1) CZ20032514A3 (pt)
HU (1) HUP0303219A2 (pt)
IL (1) IL157303A0 (pt)
MX (1) MXPA03007348A (pt)
NO (1) NO325675B1 (pt)
NZ (1) NZ527597A (pt)
PL (1) PL367285A1 (pt)
RU (1) RU2280031C2 (pt)
SK (1) SK11622003A3 (pt)
WO (1) WO2002066437A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX365950B (es) 2013-03-13 2019-06-19 Flatley Discovery Lab Llc Compuestos de piridazinona y metodos para el tratamiento de la fibrosis quistica.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4120646A1 (de) * 1991-06-22 1992-12-24 Bayer Ag 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
CA2229201A1 (en) * 1995-10-19 1997-04-24 Satoshi Sasaki Quinoline derivatives, their production and use
CA2254974A1 (en) * 1996-05-20 1997-11-27 Mark Goulet Antagonists of gonadotropin releasing hormone

Also Published As

Publication number Publication date
NO20033698L (no) 2003-10-20
PL367285A1 (en) 2005-02-21
CZ20032514A3 (cs) 2004-05-12
WO2002066437A1 (de) 2002-08-29
CA2438709A1 (en) 2002-08-29
NZ527597A (en) 2004-10-29
BG108165A (en) 2004-08-31
MXPA03007348A (es) 2003-12-04
RU2003128647A (ru) 2005-03-27
BR0207451A (pt) 2004-06-01
RU2280031C2 (ru) 2006-07-20
CN1496354A (zh) 2004-05-12
NO325675B1 (no) 2008-07-07
HUP0303219A2 (hu) 2003-12-29
NO20033698D0 (no) 2003-08-20
AU2002247737B2 (en) 2006-05-18
EP1362034A1 (de) 2003-11-19
SK11622003A3 (sk) 2004-01-08
JP2004528298A (ja) 2004-09-16

Similar Documents

Publication Publication Date Title
MXPA03001928A (es) Derivados de quinolina y quinazolina.
HUP0105133A3 (en) Quinoline derivatives and quinazoline derivatives, pharmaceutical compositions containing them and their use
SI1492771T1 (sl) Kinolinski in izokinolinski derivati, postopek za njihovo pripravo in njihova uporaba kot protivnetna sredstva
AU2223201A (en) Quinoline and quinazoline derivatives and drugs containing the same
IL165986A0 (en) Isoquinoline and quinazoline derivatives and pharmaceutical compositions containing the same
MXPA02008402A (es) Derivados de quinolina como antagonistas alfa-2.
IL161597A0 (en) Therapeutic quinoline compounds with 5-ht-antagonistic properties
IL162266A (en) Substituted 2-thio-3,5-dicyano-4- phenyl-6-aminopyridines and the use of the same
IL160750A0 (en) Quinoline derivatives as neuropeptide y antagonists
TW450031U (en) Trousers of convenience
IL157109A0 (en) Quinazolines as mmp-13 inhibitors
AU2002321878A1 (en) Pyridinone and pyridazinone derivatives as gonadotropin-releasing hormone receptor antagonists
IL157908A0 (en) Phthalazinone derivatives and pharmaceutical compositions containing the same
HUP0100832A3 (en) Quinoxaline and quinoline carboxamide derivatives, their use and the pharmaceutical compositions containing them
IL159084A0 (en) Tetrahydroisoquinoline carboxylic acid derivatives and pharmaceutical compositions containing the same
ZA200201521B (en) Alkoxy substituted benzimidazole compounds, pharmaceutical preparation containing the same, and methods of using the same.
HUP0203611A3 (en) 14,15-beta-methylene substituted androgens and their use for preparation of the medicaments
AU2002215043A1 (en) Quinoline-4-carboxamide derivatives as nk-3 and nk-2 receptor antagonists
AU2002220702A1 (en) Quinoline derivatives as nk-3 and nk-2 antagonists
AU2003224482A8 (en) Quinoline derivatives as caspase-3 inhibitor, preparation for producing the same and pharmaceutical composition comprising the same
MXPA03005855A (es) Metodo para preparacion regioselectiva de benzo[g]quinolin-3-carbonitrilos sustituidos y benzo[g]quinazolinas sustituidas.
IL157303A0 (en) Quinoline, isoquinoline and phthalazine derivatives as antagonists of the gonadotropin-releasing hormone
AU2002302735A1 (en) 3-aminoalkyl-2-aryl-indole derivatives and their use as gnrh antagonists
AU2002247737A1 (en) Quinoline, isoquinoline and phthalazine derivatives as antagonists of the gonadotropin-releasing hormone
AU2003210062A1 (en) Agonists and antagonists of gonadotropin-releasing hormone-2, and use thereof