IL157937A0 - D-hydantoinase, nucleic acid encoding the same, expression vectors including said nucleic acid and host cells expressing the same - Google Patents

D-hydantoinase, nucleic acid encoding the same, expression vectors including said nucleic acid and host cells expressing the same

Info

Publication number
IL157937A0
IL157937A0 IL15793702A IL15793702A IL157937A0 IL 157937 A0 IL157937 A0 IL 157937A0 IL 15793702 A IL15793702 A IL 15793702A IL 15793702 A IL15793702 A IL 15793702A IL 157937 A0 IL157937 A0 IL 157937A0
Authority
IL
Israel
Prior art keywords
nucleic acid
same
hydantoinase
host cells
expression vectors
Prior art date
Application number
IL15793702A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of IL157937A0 publication Critical patent/IL157937A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/02—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amides (3.5.2)
    • C12Y305/02002—Dihydropyrimidinase (3.5.2.2), i.e. hydantoinase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL15793702A 2001-04-03 2002-04-03 D-hydantoinase, nucleic acid encoding the same, expression vectors including said nucleic acid and host cells expressing the same IL157937A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28115001P 2001-04-03 2001-04-03
PCT/US2002/010437 WO2002081626A2 (en) 2001-04-03 2002-04-03 D-hydantoinase from ochrobactrum anthropi

Publications (1)

Publication Number Publication Date
IL157937A0 true IL157937A0 (en) 2004-03-28

Family

ID=23076145

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15793702A IL157937A0 (en) 2001-04-03 2002-04-03 D-hydantoinase, nucleic acid encoding the same, expression vectors including said nucleic acid and host cells expressing the same
IL157937A IL157937A (en) 2001-04-03 2003-09-16 D - Hydantoins, the nucleic acid that encodes it, expression vectors that contain this nucleic acid and surrogate cells that express it

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL157937A IL157937A (en) 2001-04-03 2003-09-16 D - Hydantoins, the nucleic acid that encodes it, expression vectors that contain this nucleic acid and surrogate cells that express it

Country Status (11)

Country Link
US (1) US6800465B2 (de)
EP (1) EP1383886B1 (de)
JP (1) JP4118689B2 (de)
AT (1) ATE402998T1 (de)
AU (1) AU2002254519B2 (de)
CA (1) CA2443377C (de)
DE (1) DE60227936D1 (de)
ES (1) ES2307746T3 (de)
IL (2) IL157937A0 (de)
MX (1) MXPA03008984A (de)
WO (1) WO2002081626A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4561010B2 (ja) * 2001-07-10 2010-10-13 味の素株式会社 D−ヒダントインハイドロラーゼをコードするdna、n−カルバミル−d−アミノ酸ハイドロラーゼをコードするdna、該遺伝子を含む組み換えdna、該組み換えdnaにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、d−アミノ酸の製造方法
JP4561009B2 (ja) * 2001-07-10 2010-10-13 味の素株式会社 D−ヒダントインハイドロラーゼをコードするdna、n−カルバミル−d−アミノ酸ハイドロラーゼをコードするdna、該遺伝子を含む組み換えdna、該組み換えdnaにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、d−アミノ酸の製造方法
US7741082B2 (en) 2004-04-14 2010-06-22 Bristol-Myers Squibb Company Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor
KR20070074574A (ko) * 2004-09-28 2007-07-12 사이토제닉, 인크. 단일-가닥 항균성 올리고뉴클레오티드 및 그의 사용
WO2011003703A1 (en) * 2009-07-09 2011-01-13 Dsm Ip Assets B.V. Stabilized enzyme compositions
WO2011003702A1 (en) * 2009-07-09 2011-01-13 Dsm Ip Assets B.V. Stabilized enzyme compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4316928C2 (de) 1993-05-19 1995-03-16 Degussa Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
CN100406553C (zh) 1994-12-28 2008-07-30 钟渊化学工业株式会社 生产D-N-氨基甲酰基-α-氨基酸的方法
EP0739978A2 (de) 1995-04-28 1996-10-30 W.R. Grace & Co.-Conn. Hydantoinase aus Agrobacterium Tumefaciens, deren Verwendung zur Herstellung von optisch-aktiven N-carbamoyl-D-Aminosäuren aus racemischen Hydantoinen
DE19519717C1 (de) 1995-05-30 1996-08-22 Degussa Neuer Mikroorganismus, dessen Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
US6524837B1 (en) 1999-03-29 2003-02-25 California Institute Of Technology Hydantoinase variants with improved properties and their use for the production of amino acids

Also Published As

Publication number Publication date
WO2002081626A2 (en) 2002-10-17
US20030013102A1 (en) 2003-01-16
US6800465B2 (en) 2004-10-05
ATE402998T1 (de) 2008-08-15
AU2002254519B2 (en) 2006-08-31
EP1383886B1 (de) 2008-07-30
JP2004525641A (ja) 2004-08-26
DE60227936D1 (de) 2008-09-11
CA2443377C (en) 2014-05-27
WO2002081626A3 (en) 2003-12-04
JP4118689B2 (ja) 2008-07-16
EP1383886A4 (de) 2005-09-07
CA2443377A1 (en) 2002-10-17
IL157937A (en) 2008-04-13
ES2307746T3 (es) 2008-12-01
EP1383886A2 (de) 2004-01-28
MXPA03008984A (es) 2004-02-18

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