ATE402998T1 - D-hydantoinase aus ochrobactrum anthropi - Google Patents

D-hydantoinase aus ochrobactrum anthropi

Info

Publication number
ATE402998T1
ATE402998T1 AT02723753T AT02723753T ATE402998T1 AT E402998 T1 ATE402998 T1 AT E402998T1 AT 02723753 T AT02723753 T AT 02723753T AT 02723753 T AT02723753 T AT 02723753T AT E402998 T1 ATE402998 T1 AT E402998T1
Authority
AT
Austria
Prior art keywords
hydantoinase
ochrobactrum anthropi
enzyme
nucleic acids
anthropi
Prior art date
Application number
AT02723753T
Other languages
English (en)
Inventor
Michael Politino
Sean Tonzi
Guna Romancik
John Usher
David Lowe
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE402998T1 publication Critical patent/ATE402998T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/02—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amides (3.5.2)
    • C12Y305/02002—Dihydropyrimidinase (3.5.2.2), i.e. hydantoinase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT02723753T 2001-04-03 2002-04-03 D-hydantoinase aus ochrobactrum anthropi ATE402998T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28115001P 2001-04-03 2001-04-03

Publications (1)

Publication Number Publication Date
ATE402998T1 true ATE402998T1 (de) 2008-08-15

Family

ID=23076145

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02723753T ATE402998T1 (de) 2001-04-03 2002-04-03 D-hydantoinase aus ochrobactrum anthropi

Country Status (11)

Country Link
US (1) US6800465B2 (de)
EP (1) EP1383886B1 (de)
JP (1) JP4118689B2 (de)
AT (1) ATE402998T1 (de)
AU (1) AU2002254519B2 (de)
CA (1) CA2443377C (de)
DE (1) DE60227936D1 (de)
ES (1) ES2307746T3 (de)
IL (2) IL157937A0 (de)
MX (1) MXPA03008984A (de)
WO (1) WO2002081626A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4561010B2 (ja) * 2001-07-10 2010-10-13 味の素株式会社 Ｄ−ヒダントインハイドロラーゼをコードするｄｎａ、ｎ−カルバミル−ｄ−アミノ酸ハイドロラーゼをコードするｄｎａ、該遺伝子を含む組み換えｄｎａ、該組み換えｄｎａにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、ｄ−アミノ酸の製造方法
JP4561009B2 (ja) * 2001-07-10 2010-10-13 味の素株式会社 Ｄ−ヒダントインハイドロラーゼをコードするｄｎａ、ｎ−カルバミル−ｄ−アミノ酸ハイドロラーゼをコードするｄｎａ、該遺伝子を含む組み換えｄｎａ、該組み換えｄｎａにより形質転換された細胞、該形質転換細胞を用いるタンパク質の製造方法、および、ｄ−アミノ酸の製造方法
US7741082B2 (en) * 2004-04-14 2010-06-22 Bristol-Myers Squibb Company Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor
EP1802754A2 (de) * 2004-09-28 2007-07-04 CytoGenix, Inc. Einzelsträngige antimikrobielle oligonukleotide und verwendungen davon
CN102482661A (zh) * 2009-07-09 2012-05-30 中化帝斯曼制药有限公司荷兰公司 经稳定化的酶组合物
WO2011003702A1 (en) * 2009-07-09 2011-01-13 Dsm Ip Assets B.V. Stabilized enzyme compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4316928C2 (de) 1993-05-19 1995-03-16 Degussa Neue Mikroorganismen, deren Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
EP1616945B1 (de) * 1994-12-28 2007-11-21 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Verfahren zur Herstellung einer D-N-Carbamoyl-alpha-Aminosäure
EP0739978A2 (de) 1995-04-28 1996-10-30 W.R. Grace & Co.-Conn. Hydantoinase aus Agrobacterium Tumefaciens, deren Verwendung zur Herstellung von optisch-aktiven N-carbamoyl-D-Aminosäuren aus racemischen Hydantoinen
DE19519717C1 (de) 1995-05-30 1996-08-22 Degussa Neuer Mikroorganismus, dessen Verwendung und Verfahren zur Herstellung von L-alpha-Aminosäuren
US6524837B1 (en) 1999-03-29 2003-02-25 California Institute Of Technology Hydantoinase variants with improved properties and their use for the production of amino acids

Also Published As

Publication number Publication date
WO2002081626A2 (en) 2002-10-17
IL157937A0 (en) 2004-03-28
EP1383886A4 (de) 2005-09-07
EP1383886A2 (de) 2004-01-28
IL157937A (en) 2008-04-13
CA2443377C (en) 2014-05-27
JP4118689B2 (ja) 2008-07-16
WO2002081626A3 (en) 2003-12-04
CA2443377A1 (en) 2002-10-17
DE60227936D1 (de) 2008-09-11
EP1383886B1 (de) 2008-07-30
MXPA03008984A (es) 2004-02-18
ES2307746T3 (es) 2008-12-01
US20030013102A1 (en) 2003-01-16
US6800465B2 (en) 2004-10-05
JP2004525641A (ja) 2004-08-26
AU2002254519B2 (en) 2006-08-31

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