IL163774A0 - Combinations comprising epothilone derivatives andalkylating agents - Google Patents

Combinations comprising epothilone derivatives andalkylating agents

Info

Publication number: IL163774A0
Authority: IL; Israel
Prior art keywords: andalkylating; agents; combinations; epothilone derivatives; hydrogen
Prior art date: 2002-03-08

Application number

IL16377403A

Other languages

English (en)

Original Assignee

Univ Newcastle

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-08

Filing date

2003-03-07

Publication date

2005-12-18

2003-03-07 Application filed by Univ Newcastle filed Critical Univ Newcastle

2005-12-18 Publication of IL163774A0 publication Critical patent/IL163774A0/xx

Links

150000003883 epothilone derivatives Chemical class 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
229940100198 alkylating agent Drugs 0.000 abstract 1
239000002168 alkylating agent Substances 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000002062 proliferating effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Silicon Polymers (AREA)

IL16377403A 2002-03-08 2003-03-07 Combinations comprising epothilone derivatives andalkylating agents IL163774A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US36273802P	2002-03-08	2002-03-08
PCT/EP2003/002364 WO2003075899A2 (en)	2002-03-08	2003-03-07	Combinations comprising epothilone derivatives and alkylating agents

Publications (1)

Publication Number	Publication Date
IL163774A0 true IL163774A0 (en)	2005-12-18

Family

ID=27805222

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
IL16377403A IL163774A0 (en)	2002-03-08	2003-03-07	Combinations comprising epothilone derivatives andalkylating agents
IL163774A IL163774A (en)	2002-03-08	2004-08-26	Combinations comprising epothilone derivatives and alkylating agents and pharmaceutical compositions comprising them
IL188859A IL188859A0 (en)	2002-03-08	2008-01-17	Combinations comprising epothilone derivatives and alkylating agents

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
IL163774A IL163774A (en)	2002-03-08	2004-08-26	Combinations comprising epothilone derivatives and alkylating agents and pharmaceutical compositions comprising them
IL188859A IL188859A0 (en)	2002-03-08	2008-01-17	Combinations comprising epothilone derivatives and alkylating agents

Country Status (22)

Country	Link
EP (1)	EP1485090B1 (da)
JP (1)	JP2005522461A (da)
KR (1)	KR20040101274A (da)
CN (2)	CN1939299A (da)
AT (1)	ATE375157T1 (da)
AU (1)	AU2003223958B2 (da)
BR (1)	BR0308258A (da)
CA (1)	CA2478223C (da)
CY (1)	CY1107126T1 (da)
DE (1)	DE60316775T2 (da)
DK (1)	DK1485090T3 (da)
ES (1)	ES2295575T3 (da)
HU (1)	HUP0500092A2 (da)
IL (3)	IL163774A0 (da)
MX (1)	MXPA04008707A (da)
NO (1)	NO20044208L (da)
NZ (1)	NZ535081A (da)
PL (1)	PL371098A1 (da)
PT (1)	PT1485090E (da)
RU (1)	RU2341260C2 (da)
WO (1)	WO2003075899A2 (da)
ZA (1)	ZA200406790B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1999001124A1 (en)	1996-12-03	1999-01-14	Sloan-Kettering Institute For Cancer Research	Synthesis of epothilones, intermediates thereto, analogues and uses thereof
ES2587381T3 (es)	2007-04-25	2016-10-24	Cyclacel Limited	Uso de sapacitabina para tratar una enfermedad proliferativa
AU2011255647A1 (en)	2010-05-18	2012-11-15	Cerulean Pharma Inc.	Compositions and methods for treatment of autoimmune and other diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6515016B2 (en) *	1996-12-02	2003-02-04	Angiotech Pharmaceuticals, Inc.	Composition and methods of paclitaxel for treating psoriasis
PT975638E (pt) *	1997-02-25	2002-12-31	Biotechnolog Forschung Mbh Gbf	Epothilons modificados nas cadeias laterais
US6320045B1 (en) *	1997-12-04	2001-11-20	Bristol-Myers Squibb Company	Process for the reduction of oxiranyl epothilones to olefinic epothilones
EP1051490A2 (en) *	1998-01-30	2000-11-15	Cold Spring Harbor Laboratory	Modulation of cell proliferation, methods and reagents
BR0008379A (pt) *	1999-02-22	2002-09-24	Biotechnolog Forschung Gmbh	Epotilonas modificadas em c-21
UA75365C2 (en) *	2000-08-16	2006-04-17	Bristol Myers Squibb Co	Epothilone analog polymorph modifications, a method for obtaining thereof (variants), a pharmaceutical composition based thereon

2003
- 2003-03-07 EP EP03720323A patent/EP1485090B1/en not_active Expired - Lifetime
- 2003-03-07 CN CNA2006100879160A patent/CN1939299A/zh active Pending
- 2003-03-07 MX MXPA04008707A patent/MXPA04008707A/es active IP Right Grant
- 2003-03-07 IL IL16377403A patent/IL163774A0/xx unknown
- 2003-03-07 KR KR10-2004-7014013A patent/KR20040101274A/ko not_active Ceased
- 2003-03-07 NZ NZ535081A patent/NZ535081A/en not_active IP Right Cessation
- 2003-03-07 BR BR0308258-0A patent/BR0308258A/pt not_active IP Right Cessation
- 2003-03-07 DE DE60316775T patent/DE60316775T2/de not_active Expired - Lifetime
- 2003-03-07 AU AU2003223958A patent/AU2003223958B2/en not_active Ceased
- 2003-03-07 PL PL03371098A patent/PL371098A1/xx not_active Application Discontinuation
- 2003-03-07 HU HU0500092A patent/HUP0500092A2/hu unknown
- 2003-03-07 CA CA2478223A patent/CA2478223C/en not_active Expired - Fee Related
- 2003-03-07 CN CNB038055309A patent/CN100402029C/zh not_active Expired - Fee Related
- 2003-03-07 PT PT03720323T patent/PT1485090E/pt unknown
- 2003-03-07 DK DK03720323T patent/DK1485090T3/da active
- 2003-03-07 ES ES03720323T patent/ES2295575T3/es not_active Expired - Lifetime
- 2003-03-07 RU RU2004130283/15A patent/RU2341260C2/ru not_active IP Right Cessation
- 2003-03-07 JP JP2003574174A patent/JP2005522461A/ja not_active Withdrawn
- 2003-03-07 AT AT03720323T patent/ATE375157T1/de active
- 2003-03-07 WO PCT/EP2003/002364 patent/WO2003075899A2/en not_active Ceased
2004
- 2004-08-26 IL IL163774A patent/IL163774A/en not_active IP Right Cessation
- 2004-08-26 ZA ZA200406790A patent/ZA200406790B/en unknown
- 2004-10-04 NO NO20044208A patent/NO20044208L/no not_active Application Discontinuation
2008
- 2008-01-03 CY CY20081100012T patent/CY1107126T1/el unknown
- 2008-01-17 IL IL188859A patent/IL188859A0/en unknown

Also Published As

Publication number	Publication date
NZ535081A (en)	2007-05-31
EP1485090A2 (en)	2004-12-15
HUP0500092A2 (hu)	2005-04-28
DE60316775D1 (de)	2007-11-22
EP1485090B1 (en)	2007-10-10
ATE375157T1 (de)	2007-10-15
BR0308258A (pt)	2005-01-04
AU2003223958B2 (en)	2007-04-19
JP2005522461A (ja)	2005-07-28
CN1939299A (zh)	2007-04-04
KR20040101274A (ko)	2004-12-02
IL163774A (en)	2010-12-30
AU2003223958A1 (en)	2003-09-22
CN100402029C (zh)	2008-07-16
CN1638767A (zh)	2005-07-13
ES2295575T3 (es)	2008-04-16
NO20044208D0 (no)	2004-10-04
NO20044208L (no)	2004-10-14
WO2003075899A2 (en)	2003-09-18
CA2478223C (en)	2012-05-15
HK1072723A1 (en)	2005-09-09
ZA200406790B (en)	2006-05-31
PL371098A1 (en)	2005-06-13
RU2341260C2 (ru)	2008-12-20
IL188859A0 (en)	2008-04-13
WO2003075899A3 (en)	2004-03-11
DE60316775T2 (de)	2008-04-30
MXPA04008707A (es)	2006-03-08
DK1485090T3 (da)	2008-02-04
PT1485090E (pt)	2008-01-14
CA2478223A1 (en)	2003-09-18
RU2004130283A (ru)	2005-08-10
CY1107126T1 (el)	2012-10-24

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ATE302775T1 (de)	2005-09-15	Carbolinderivate
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