IL165568A0 - N,N-disubstituted diazocycloalkanes useful for thetreatment of CNS disorders due to serotonergic - Google Patents
N,N-disubstituted diazocycloalkanes useful for thetreatment of CNS disorders due to serotonergicInfo
- Publication number
- IL165568A0 IL165568A0 IL16556804A IL16556804A IL165568A0 IL 165568 A0 IL165568 A0 IL 165568A0 IL 16556804 A IL16556804 A IL 16556804A IL 16556804 A IL16556804 A IL 16556804A IL 165568 A0 IL165568 A0 IL 165568A0
- Authority
- IL
- Israel
- Prior art keywords
- thetreatment
- serotonergic
- useful
- cns disorders
- disorders due
- Prior art date
Links
- 208000015114 central nervous system disease Diseases 0.000 title 1
- 230000000862 serotonergic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Gynecology & Obstetrics (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002MI001328A ITMI20021328A1 (it) | 2002-06-14 | 2002-06-14 | Nuove piperazine 1,4 - disostituite |
| PCT/EP2003/006280 WO2003106444A1 (en) | 2002-06-14 | 2003-06-16 | N,n-disubstituted diazocycloalkanes useful for the treatment of cns disorders due to serotonergic dysfunction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL165568A0 true IL165568A0 (en) | 2006-01-15 |
Family
ID=29727277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16556804A IL165568A0 (en) | 2002-06-14 | 2004-12-06 | N,N-disubstituted diazocycloalkanes useful for thetreatment of CNS disorders due to serotonergic |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20060148821A1 (sr) |
| EP (1) | EP1515961A1 (sr) |
| JP (1) | JP2005538063A (sr) |
| CN (1) | CN1662516A (sr) |
| AU (1) | AU2003276979A1 (sr) |
| BR (1) | BR0311805A (sr) |
| CA (1) | CA2489450A1 (sr) |
| EA (1) | EA007503B1 (sr) |
| HR (1) | HRP20050034A2 (sr) |
| IL (1) | IL165568A0 (sr) |
| IT (1) | ITMI20021328A1 (sr) |
| MX (1) | MXPA04012602A (sr) |
| NO (1) | NO20050146L (sr) |
| NZ (1) | NZ537469A (sr) |
| PL (1) | PL372531A1 (sr) |
| RS (1) | RS108904A (sr) |
| TW (1) | TW200400947A (sr) |
| WO (1) | WO2003106444A1 (sr) |
| ZA (1) | ZA200500318B (sr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7365076B2 (en) * | 2003-10-14 | 2008-04-29 | Wyeth | Substituted aryl cycloalkanol derivatives and methods of their use |
| US20050165025A1 (en) * | 2004-01-22 | 2005-07-28 | Recordati Ireland Ltd. | Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists |
| IN2012DN01453A (sr) | 2009-08-20 | 2015-06-05 | Novartis Ag |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU9256498A (en) * | 1997-08-01 | 1999-02-22 | Recordati S.A. Chemical And Pharmaceutical Company | 1,4-disubstituted piperazines |
| IT1293804B1 (it) * | 1997-08-01 | 1999-03-10 | Recordati Chem Pharm | Diarilalchilpiperazine attive sulle basse vie urinarie |
| UA66370C2 (en) * | 1997-12-16 | 2004-05-17 | Lilly Co Eli | Arylpiperazines having activity to setotonin 1 receptors |
-
2002
- 2002-06-14 IT IT2002MI001328A patent/ITMI20021328A1/it unknown
-
2003
- 2003-06-16 BR BR0311805-3A patent/BR0311805A/pt not_active IP Right Cessation
- 2003-06-16 CN CN038142643A patent/CN1662516A/zh active Pending
- 2003-06-16 JP JP2004513276A patent/JP2005538063A/ja active Pending
- 2003-06-16 CA CA002489450A patent/CA2489450A1/en not_active Abandoned
- 2003-06-16 PL PL03372531A patent/PL372531A1/xx unknown
- 2003-06-16 TW TW092116282A patent/TW200400947A/zh unknown
- 2003-06-16 WO PCT/EP2003/006280 patent/WO2003106444A1/en not_active Ceased
- 2003-06-16 RS YUP-1089/04A patent/RS108904A/sr unknown
- 2003-06-16 EP EP03740249A patent/EP1515961A1/en not_active Withdrawn
- 2003-06-16 AU AU2003276979A patent/AU2003276979A1/en not_active Abandoned
- 2003-06-16 NZ NZ537469A patent/NZ537469A/en unknown
- 2003-06-16 HR HR20050034A patent/HRP20050034A2/hr not_active Application Discontinuation
- 2003-06-16 MX MXPA04012602A patent/MXPA04012602A/es unknown
- 2003-06-16 EA EA200500023A patent/EA007503B1/ru unknown
-
2004
- 2004-12-06 IL IL16556804A patent/IL165568A0/xx unknown
-
2005
- 2005-01-11 NO NO20050146A patent/NO20050146L/no not_active Application Discontinuation
- 2005-01-13 ZA ZA200500318A patent/ZA200500318B/en unknown
-
2006
- 2006-02-27 US US11/364,653 patent/US20060148821A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EA200500023A1 (ru) | 2005-06-30 |
| WO2003106444A8 (en) | 2004-08-12 |
| US20060148821A1 (en) | 2006-07-06 |
| EA007503B1 (ru) | 2006-10-27 |
| TW200400947A (en) | 2004-01-16 |
| RS108904A (sr) | 2007-02-05 |
| EP1515961A1 (en) | 2005-03-23 |
| HRP20050034A2 (en) | 2005-08-31 |
| CN1662516A (zh) | 2005-08-31 |
| ITMI20021328A1 (it) | 2003-12-15 |
| WO2003106444A1 (en) | 2003-12-24 |
| CA2489450A1 (en) | 2003-12-24 |
| NO20050146L (no) | 2005-03-14 |
| AU2003276979A1 (en) | 2003-12-31 |
| NZ537469A (en) | 2006-07-28 |
| MXPA04012602A (es) | 2005-09-30 |
| BR0311805A (pt) | 2005-03-15 |
| PL372531A1 (en) | 2005-07-25 |
| ZA200500318B (en) | 2006-07-26 |
| NO20050146D0 (no) | 2005-01-11 |
| JP2005538063A (ja) | 2005-12-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL376524A1 (pl) | Nowe hydroksyindole, ich zastosowanie jako inhibitorów fosfodiesterazy 4 i sposób ich wytwarzania | |
| ZA200801888B (en) | Derivatives of 4-piperazin-1-1-YL-4-benzo [B] thiophene suitable for the treatment of CNS disorders | |
| TW200407305A (en) | Novel compounds | |
| WO2005013914A3 (en) | Heteroarylaminosulfonylphenyl derivatives for use as sodium or calcium channel blockers in the treatment of pain | |
| IL164516A0 (en) | 2,6-Quimolinyl and 2,6-naphthyl derivatives, processes for preparation them and their uses as vla-4 inhibitors | |
| IL165051A0 (en) | New compounds useful for the treatment of obesity,type II diabetes and cns disorders | |
| WO2006049734A3 (en) | Quetiapine analogs and methods of use thereof | |
| ZA200702523B (en) | Process for the purification of 1,4-butanediol | |
| TW200514781A (en) | Novel compounds | |
| ZA200507297B (en) | Process for preparation of phenethylamine derivatives | |
| TWI367215B (en) | Method for the preparation of purified elastomers from solution | |
| IL180513A0 (en) | Process for synthesis of 4-4'-diamino-diphenyl-sulfone | |
| EP1404308A4 (en) | TREATMENT OF SECONDARY DISORDERS CAUSED BY ORGANIC DEFICIENCIES | |
| GB0229033D0 (en) | Purification of nanotubes | |
| HRP20030965A2 (en) | Process for production of (s)-n-pentanoyl-n-[[2'-( | |
| PL372531A1 (en) | N,n-disubstituted diazocycloalkanes useful for the treatment of cns disorders due to serotonergic dysfunction | |
| MX2007003922A (es) | Nuevas propenonas ciclicas y aciclicas para tratar trastornos del sistema nervioso central. | |
| NO20050885L (no) | Ny fremgangsmate for syntesen av 1,3-dihydro-2H-3-benzazepin-2-onforbindelser, og anvendelse i syntesen av ivabradin og addisjonssalter derav med en farmasoytisk akseptabel syre | |
| HK1070059A (en) | N, n-disubstituted diazocycloalkanes useful for the treatment of cns disorders due to serotonergic dysfunction | |
| AU2002247949A1 (en) | Process for synthesis of trans-alkenoic acid, use thereof | |
| SI1656358T1 (sl) | Stabilen polimorf bifeprunox mezilata | |
| AU2003243214A1 (en) | Salts of bis-arylsulfones for the treatment of cns disorders | |
| AU2003239967A1 (en) | Compound for the treatment of cns disorders | |
| IL173709A0 (en) | Process for the purification of terbinafine | |
| EG24122A (en) | Process for the synthesis of 3-cyano-6-alkoxy-7-nitro-4-quinolines |