IL39341A - Thieno(3,2-d)pyrimidines,their preparation and pharmaceutical compositions containing them - Google Patents

Thieno(3,2-d)pyrimidines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL39341A
IL39341A IL39341A IL3934172A IL39341A IL 39341 A IL39341 A IL 39341A IL 39341 A IL39341 A IL 39341A IL 3934172 A IL3934172 A IL 3934172A IL 39341 A IL39341 A IL 39341A
Authority
IL
Israel
Prior art keywords
thieno
pyrimidines
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL39341A
Other languages
English (en)
Other versions
IL39341A0 (en
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19712121950 external-priority patent/DE2121950A1/de
Priority claimed from DE19712137341 external-priority patent/DE2137341A1/de
Priority claimed from DE19722215299 external-priority patent/DE2215299A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL39341A0 publication Critical patent/IL39341A0/xx
Publication of IL39341A publication Critical patent/IL39341A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL39341A 1971-05-04 1972-05-03 Thieno(3,2-d)pyrimidines,their preparation and pharmaceutical compositions containing them IL39341A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19712121950 DE2121950A1 (en) 1971-05-04 1971-05-04 Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity
DE19712137341 DE2137341A1 (de) 1971-07-26 1971-07-26 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine
DE19722215299 DE2215299A1 (de) 1972-03-29 1972-03-29 Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine

Publications (2)

Publication Number Publication Date
IL39341A0 IL39341A0 (en) 1972-07-26
IL39341A true IL39341A (en) 1975-08-31

Family

ID=27183398

Family Applications (1)

Application Number Title Priority Date Filing Date
IL39341A IL39341A (en) 1971-05-04 1972-05-03 Thieno(3,2-d)pyrimidines,their preparation and pharmaceutical compositions containing them

Country Status (15)

Country Link
US (1) US3888851A (pl)
AT (1) AT318619B (pl)
AU (1) AU4181572A (pl)
BE (1) BE783044A (pl)
BG (1) BG20593A3 (pl)
DD (1) DD97656A5 (pl)
DK (1) DK129844B (pl)
ES (1) ES402302A1 (pl)
FR (1) FR2135294B1 (pl)
GB (1) GB1393161A (pl)
HU (1) HU163960B (pl)
IL (1) IL39341A (pl)
NL (1) NL7206041A (pl)
PL (1) PL82381B1 (pl)
RO (1) RO62428A (pl)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054656A (en) * 1975-09-10 1977-10-18 Mead Johnson & Company Thieno[2,3-d]pyrimidine antiallergic agents
US5098902A (en) * 1991-03-18 1992-03-24 Warner-Lambert Company Method of treating neurodegenerative diseases
JPH08828B2 (ja) * 1992-02-19 1996-01-10 ファイザー・インコーポレーテッド 抗腫瘍活性を高めるための複素環化合物
BR9812944A (pt) 1997-10-20 2000-08-08 Hoffmann La Roche Inibidores bicìclicos da cinase
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
GB0423653D0 (en) 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
RS51163B (sr) * 2006-04-19 2010-10-31 Boehringer Ingelheim International Gmbh. Dihidrotienopirimidin za lečenje zapaljenskih bolesti
TW200801012A (en) 2006-04-26 2008-01-01 Piramed Ltd Phosphoinositide 3-kinase inhibitor compounds and methods of use
TWI498332B (zh) 2006-04-26 2015-09-01 Hoffmann La Roche 作為pi3k抑制劑之嘧啶衍生物及相關製備方法、醫藥組合物、用途、套組及產物
WO2007129161A2 (en) 2006-04-26 2007-11-15 F. Hoffmann-La Roche Ag Thieno [3, 2-d] pyrimidine derivative useful as pi3k inhibitor
RU2470936C2 (ru) 2006-12-07 2012-12-27 Дженентек, Инк. Соединения-ингибиторы фосфоинозитид 3-киназы и способы применения
MX2009005950A (es) 2006-12-07 2009-10-12 Genentech Inc Compuestos inhibidores de fosfoinositido 3-quinasas y metodos de uso.
CA2704711C (en) 2007-09-24 2016-07-05 Genentech, Inc. Thiazolopyrimidine p13k inhibitor compounds and methods of use
EP2205609B1 (de) * 2007-10-19 2017-03-29 Boehringer Ingelheim International GmbH Heterocyclus-substituierte piperazino-dihydrothienopyrimidine
JP5348725B2 (ja) * 2007-10-25 2013-11-20 ジェネンテック， インコーポレイテッド チエノピリミジン化合物の製造方法
GB0721095D0 (en) 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
JP5709766B2 (ja) 2009-03-12 2015-04-30 ジェネンテック， インコーポレイテッド 造血器腫瘍の治療のためのホスホイノシチド３キナーゼ阻害剤化合物と化学療法剤の併用
US8158625B2 (en) * 2009-05-27 2012-04-17 Genentech, Inc. Bicyclic indole-pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of use
BRPI1009022A2 (pt) * 2009-05-27 2016-03-08 Hoffmann La Roche "composto, composição farmacêutica, processo para produzir uma composição farmacêutica, uso de um composto, método para tratamento de uma doença ou transtorno e kit"
WO2011130654A1 (en) 2010-04-16 2011-10-20 Genentech, Inc. Fox03a as predictive biomarker for pi3k/akt kinase pathway inhibitor efficacy
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
EP2959014B1 (en) 2013-02-25 2019-11-13 Genentech, Inc. Methods and compositions for detecting and treating drug resistant akt mutant
GB201410816D0 (en) * 2014-06-17 2014-07-30 Ucb Biopharma Sprl And Katholieke Universiteit Leuven Therapeutic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3259623A (en) * 1963-06-14 1966-07-05 Olin Mathieson Process for preparing 2-(secondary amino)-halogenopyrimidines
DE1470356A1 (de) * 1964-01-15 1970-04-30 Thomae Gmbh Dr K Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
US3210368A (en) * 1964-09-29 1965-10-05 Ciba Geigy Corp Certain 2-amino-4-aryl-5-n, n-disubstituted amino-lower alkyl-thiazole compounds

Also Published As

Publication number Publication date
ES402302A1 (es) 1975-04-01
NL7206041A (pl) 1972-11-07
AT318619B (de) 1974-11-11
DK129844B (da) 1974-11-25
BE783044A (fr) 1972-11-06
IL39341A0 (en) 1972-07-26
FR2135294A1 (pl) 1972-12-15
GB1393161A (en) 1975-05-07
HU163960B (pl) 1973-11-28
DD97656A5 (pl) 1973-05-12
FR2135294B1 (pl) 1975-10-17
RO62428A (fr) 1978-01-15
US3888851A (en) 1975-06-10
BG20593A3 (bg) 1975-12-05
PL82381B1 (pl) 1975-10-31
DK129844C (pl) 1975-05-12
AU4181572A (en) 1973-11-08

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