RO62428A - Procede pour la preparation des thyeno-(3,2-d)-pyrimidines - Google Patents

Procede pour la preparation des thyeno-(3,2-d)-pyrimidines

Info

Publication number: RO62428A
Authority: RO; Romania
Prior art keywords: thyeno; pyrimidines; preparation
Prior art date: 1971-05-04

Application number

RO7200070735A

Other languages

English (en)

French (fr)

Inventor

Berthold Narr

Josef Roch

Erich Mueller

Josef Nickl

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-05-04

Filing date

1972-04-28

Publication date

1978-01-15

1971-05-04 Priority claimed from DE19712121950 external-priority patent/DE2121950A1/de

1971-07-26 Priority claimed from DE19712137341 external-priority patent/DE2137341A1/de

1972-03-29 Priority claimed from DE19722215299 external-priority patent/DE2215299A1/de

1972-04-28 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1978-01-15 Publication of RO62428A publication Critical patent/RO62428A/ro

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

RO7200070735A 1971-05-04 1972-04-28 Procede pour la preparation des thyeno-(3,2-d)-pyrimidines RO62428A (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE19712121950 DE2121950A1 (en)	1971-05-04	1971-05-04	Thieno(3,2-d)pyrimidine derivs - with thrombocyte aggregation inhibiting activity
DE19712137341 DE2137341A1 (de)	1971-07-26	1971-07-26	Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine
DE19722215299 DE2215299A1 (de)	1972-03-29	1972-03-29	Neue thieno eckige klammer auf 3,2-d eckige klammer zu pyrimidine

Publications (1)

Publication Number	Publication Date
RO62428A true RO62428A (fr)	1978-01-15

Family

ID=27183398

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
RO7200070735A RO62428A (fr)	1971-05-04	1972-04-28	Procede pour la preparation des thyeno-(3,2-d)-pyrimidines

Country Status (15)

Country	Link
US (1)	US3888851A (ro)
AT (1)	AT318619B (ro)
AU (1)	AU4181572A (ro)
BE (1)	BE783044A (ro)
BG (1)	BG20593A3 (ro)
DD (1)	DD97656A5 (ro)
DK (1)	DK129844B (ro)
ES (1)	ES402302A1 (ro)
FR (1)	FR2135294B1 (ro)
GB (1)	GB1393161A (ro)
HU (1)	HU163960B (ro)
IL (1)	IL39341A (ro)
NL (1)	NL7206041A (ro)
PL (1)	PL82381B1 (ro)
RO (1)	RO62428A (ro)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4054656A (en) *	1975-09-10	1977-10-18	Mead Johnson & Company	Thieno[2,3-d]pyrimidine antiallergic agents
US5098902A (en) *	1991-03-18	1992-03-24	Warner-Lambert Company	Method of treating neurodegenerative diseases
CA2129337A1 (en) *	1992-02-19	1993-09-02	Jotham W. Coe	Heterocyclic compounds for enhancing antitumor activity
ES2221213T3 (es)	1997-10-20	2004-12-16	F. Hoffmann-La Roche Ag	Inhibidores de kinasa biciclicos.
US6187777B1 (en)	1998-02-06	2001-02-13	Amgen Inc.	Compounds and methods which modulate feeding behavior and related diseases
GB0423653D0 (en)	2004-10-25	2004-11-24	Piramed Ltd	Pharmaceutical compounds
MX2007012313A (es) *	2006-04-19	2007-11-21	Boehringer Ingelheim Int	Dihidrotienopirimidinas para el tratamiento de enfermedades inflamatorias.
TWI498332B (zh)	2006-04-26	2015-09-01	Hoffmann La Roche	作為pi3k抑制劑之嘧啶衍生物及相關製備方法、醫藥組合物、用途、套組及產物
CN101511840A (zh)	2006-04-26	2009-08-19	吉宁特有限公司	磷酸肌醇3-激酶抑制剂化合物及其使用方法
MX2008013578A (es)	2006-04-26	2009-03-23	Hoffmann La Roche	Derivados de tieno [3,2-d]pirimidina utiles como inhibidores de fosfatidilinositol 3-cinasa(p13k).
ES2571028T3 (es) *	2006-12-07	2016-05-23	Genentech Inc	Compuestos inhibidores de fosfoinositida 3-cinasa y métodos de uso
WO2008070740A1 (en)	2006-12-07	2008-06-12	F.Hoffmann-La Roche Ag	Phosphoinositide 3-kinase inhibitor compounds and methods of use
WO2009042607A1 (en)	2007-09-24	2009-04-02	Genentech, Inc.	Thiazolopyrimidine p13k inhibitor compounds and methods of use
EP2205609B1 (de) *	2007-10-19	2017-03-29	Boehringer Ingelheim International GmbH	Heterocyclus-substituierte piperazino-dihydrothienopyrimidine
US8354528B2 (en)	2007-10-25	2013-01-15	Genentech, Inc.	Process for making thienopyrimidine compounds
GB0721095D0 (en)	2007-10-26	2007-12-05	Piramed Ltd	Pharmaceutical compounds
CN102369011A (zh)	2009-03-12	2012-03-07	健泰科生物技术公司	用于治疗造血恶性肿瘤的磷酸肌醇3-激酶抑制剂化合物与化学治疗剂的组合
CA2772371A1 (en) *	2009-05-27	2010-12-02	F. Hoffmann-La Roche Ag	Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
CN102459272B (zh) *	2009-05-27	2014-08-06	健泰科生物技术公司	对P110δ具有选择性的为PI3K抑制剂的二环嘧啶化合物和使用方法
MX2012011887A (es)	2010-04-16	2012-11-30	Genentech Inc	Foxo 3a como biomarcador predictivo para la eficacia del inhibidor de la via de quinasa pi3k/akt.
WO2012088254A1 (en)	2010-12-22	2012-06-28	Genentech, Inc.	Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
CA2901126C (en)	2013-02-25	2022-01-25	Genentech, Inc.	Methods and compositions for detecting and treating drug resistant akt mutant
GB201410816D0 (en) *	2014-06-17	2014-07-30	Ucb Biopharma Sprl And Katholieke Universiteit Leuven	Therapeutic agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3259623A (en) *	1963-06-14	1966-07-05	Olin Mathieson	Process for preparing 2-(secondary amino)-halogenopyrimidines
DE1470356A1 (de) *	1964-01-15	1970-04-30	Thomae Gmbh Dr K	Neue Thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
US3210368A (en) *	1964-09-29	1965-10-05	Ciba Geigy Corp	Certain 2-amino-4-aryl-5-n, n-disubstituted amino-lower alkyl-thiazole compounds

1972
- 1972-04-28 RO RO7200070735A patent/RO62428A/ro unknown
- 1972-05-02 HU HUTO875A patent/HU163960B/hu unknown
- 1972-05-02 ES ES402302A patent/ES402302A1/es not_active Expired
- 1972-05-03 AU AU41815/72A patent/AU4181572A/en not_active Expired
- 1972-05-03 DD DD162711A patent/DD97656A5/xx unknown
- 1972-05-03 DK DK219672AA patent/DK129844B/da unknown
- 1972-05-03 US US249782A patent/US3888851A/en not_active Expired - Lifetime
- 1972-05-03 BG BG020371A patent/BG20593A3/xx unknown
- 1972-05-03 GB GB2058472A patent/GB1393161A/en not_active Expired
- 1972-05-03 IL IL39341A patent/IL39341A/xx unknown
- 1972-05-03 PL PL1972155128A patent/PL82381B1/pl unknown
- 1972-05-03 AT AT382972A patent/AT318619B/de not_active IP Right Cessation
- 1972-05-04 BE BE783044A patent/BE783044A/xx unknown
- 1972-05-04 NL NL7206041A patent/NL7206041A/xx unknown
- 1972-05-04 FR FR7215929A patent/FR2135294B1/fr not_active Expired

Also Published As

Publication number	Publication date
BG20593A3 (bg)	1975-12-05
IL39341A (en)	1975-08-31
DK129844B (da)	1974-11-25
BE783044A (fr)	1972-11-06
NL7206041A (ro)	1972-11-07
FR2135294B1 (ro)	1975-10-17
GB1393161A (en)	1975-05-07
HU163960B (ro)	1973-11-28
PL82381B1 (ro)	1975-10-31
AT318619B (de)	1974-11-11
IL39341A0 (en)	1972-07-26
ES402302A1 (es)	1975-04-01
US3888851A (en)	1975-06-10
DK129844C (ro)	1975-05-12
FR2135294A1 (ro)	1972-12-15
DD97656A5 (ro)	1973-05-12
AU4181572A (en)	1973-11-08

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