IL45384A0 - A process for the preparation of methylcobalamin from cyanocobalamin - Google Patents

A process for the preparation of methylcobalamin from cyanocobalamin

Info

Publication number: IL45384A0
Authority: IL; Israel
Prior art keywords: methylcobalamin; cyanocobalamin; preparation
Prior art date: 1973-08-08

Application number

IL45384A

Other versions

IL45384A (en

Original Assignee

Opochimie L

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-08-08

Filing date

1974-08-02

Publication date

1974-11-29

1973-08-08 Priority claimed from FR7328998A external-priority patent/FR2240232A1/en

1973-12-28 Priority claimed from FR7346829A external-priority patent/FR2256174A2/en

1974-08-02 Application filed by Opochimie L filed Critical Opochimie L

1974-11-29 Publication of IL45384A0 publication Critical patent/IL45384A0/en

1976-09-30 Publication of IL45384A publication Critical patent/IL45384A/en

Links

RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 title 2
235000000639 cyanocobalamin Nutrition 0.000 title 1
239000011666 cyanocobalamin Substances 0.000 title 1
229960002104 cyanocobalamin Drugs 0.000 title 1
235000007672 methylcobalamin Nutrition 0.000 title 1
239000011585 methylcobalamin Substances 0.000 title 1
JEWJRMKHSMTXPP-BYFNXCQMSA-M methylcobalamin Chemical compound C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O JEWJRMKHSMTXPP-BYFNXCQMSA-M 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL45384A 1973-08-08 1974-08-02 Process for the preparation of methylcobalamine from cyanocobalamine IL45384A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR7328998A FR2240232A1 (en)	1973-08-08	1973-08-08	Methylcobalamine prepn from cyanocobalamine - by reduction and methylation using methyl acid oxalate and a metal
FR7346829A FR2256174A2 (en)	1973-12-28	1973-12-28	Methylcobalamine prepn from cyanocobalamine - by reduction and methylation using methyl acid oxalate and a metal

Publications (2)

Publication Number	Publication Date
IL45384A0 true IL45384A0 (en)	1974-11-29
IL45384A IL45384A (en)	1976-09-30

Family

ID=26217885

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL45384A IL45384A (en)	1973-08-08	1974-08-02	Process for the preparation of methylcobalamine from cyanocobalamine

Country Status (16)

Country	Link
JP (1)	JPS5727119B2 (en)
AR (1)	AR199756A1 (en)
CA (1)	CA1019726A (en)
CH (1)	CH583744A5 (en)
DE (1)	DE2434967A1 (en)
DK (1)	DK136775B (en)
ES (1)	ES428798A1 (en)
GB (1)	GB1419933A (en)
IE (1)	IE41823B1 (en)
IL (1)	IL45384A (en)
IN (1)	IN139935B (en)
LU (1)	LU70582A1 (en)
NL (1)	NL7410061A (en)
NO (1)	NO742545L (en)
OA (1)	OA04753A (en)
SE (1)	SE412589B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2151773C1 (en) *	1999-03-10	2000-06-27	Казанский государственный университет им. В.И. Ульянова-Ленина	TETRAKIS-(L-HISTIDINATO)-μ-PEROXYDICOBALT)III HEPTAHYDRATE HAVING ANTIANEMIC, RADIOPROTECTIVE AND ANTIARRHYTHMIC ACTIVITIES
JP4358615B2 (en)	2001-06-05	2009-11-04	エーザイ・アール・アンド・ディー・マネジメント株式会社	Method for producing methylcobalamin
CN102391340A (en) *	2011-10-31	2012-03-28	河北玉星生物工程有限公司	Preparation method of mecobalamin
PL3481839T3 (en) *	2016-07-08	2023-10-02	HealthTech Bio Actives, S.L.U.	Process for the purification of methylcobalamin
CN114874276B (en) *	2022-04-21	2024-06-21	南京工业大学	Improved method for synthesizing mecobalamin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE789252A (en) *	1971-11-10	1973-03-26	Boige Jean	METHOD FOR MANUFACTURING METHYLCOBALAMINE

1974
- 1974-07-12 NO NO742545A patent/NO742545L/no unknown
- 1974-07-17 DK DK386274AA patent/DK136775B/en unknown
- 1974-07-19 DE DE2434967A patent/DE2434967A1/en active Pending
- 1974-07-22 LU LU70582A patent/LU70582A1/xx unknown
- 1974-07-23 CA CA205,451A patent/CA1019726A/en not_active Expired
- 1974-07-24 IN IN1642/CAL/74A patent/IN139935B/en unknown
- 1974-07-25 NL NL7410061A patent/NL7410061A/en unknown
- 1974-07-26 AR AR254903A patent/AR199756A1/en active
- 1974-07-26 OA OA55258A patent/OA04753A/en unknown
- 1974-07-29 CH CH1040374A patent/CH583744A5/xx not_active IP Right Cessation
- 1974-07-31 ES ES428798A patent/ES428798A1/en not_active Expired
- 1974-08-01 GB GB3400874A patent/GB1419933A/en not_active Expired
- 1974-08-02 IL IL45384A patent/IL45384A/en unknown
- 1974-08-02 SE SE7410005A patent/SE412589B/en unknown
- 1974-08-06 IE IE1654/74A patent/IE41823B1/en unknown
- 1974-08-07 JP JP8995074A patent/JPS5727119B2/ja not_active Expired

Also Published As

Publication number	Publication date
IL45384A (en)	1976-09-30
GB1419933A (en)	1975-12-31
IN139935B (en)	1976-08-21
AU7188674A (en)	1976-02-05
ES428798A1 (en)	1976-09-16
DK136775C (en)	1978-05-08
OA04753A (en)	1980-08-31
NO742545L (en)	1975-03-10
DE2434967A1 (en)	1975-02-20
CA1019726A (en)	1977-10-25
SE7410005L (en)	1975-02-10
NL7410061A (en)	1975-02-11
CH583744A5 (en)	1977-01-14
IE41823B1 (en)	1980-04-09
AR199756A1 (en)	1974-09-23
SE412589B (en)	1980-03-10
IE41823L (en)	1975-02-08
DK386274A (en)	1975-04-01
LU70582A1 (en)	1976-05-31
DK136775B (en)	1977-11-21
JPS5041900A (en)	1975-04-16
JPS5727119B2 (en)	1982-06-08

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