IL75887A - 9-substituted-indolo(6,5,4-cd)indole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

9-substituted-indolo(6,5,4-cd)indole derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL75887A
Authority: IL; Israel
Prior art keywords: indolo; substituted; preparation; pharmaceutical compositions; compositions containing
Prior art date: 1984-07-27

Application number

IL75887A

Other languages

English (en)

Other versions

IL75887A0 (en

Original Assignee

Lilly Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-07-27

Filing date

1985-07-23

Publication date

1988-05-31

1985-07-23 Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd

1985-12-31 Publication of IL75887A0 publication Critical patent/IL75887A0/xx

1988-05-31 Publication of IL75887A publication Critical patent/IL75887A/xx

Links

-1 9-substituted-indolo(6,5,4-cd)indole Chemical class 0.000 title 1
229940054051 antipsychotic indole derivative Drugs 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000001931 aliphatic group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL75887A 1984-07-27 1985-07-23 9-substituted-indolo(6,5,4-cd)indole derivatives,their preparation and pharmaceutical compositions containing them IL75887A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB848419278A GB8419278D0 (en)	1984-07-27	1984-07-27	Pharmaceutical compounds

Publications (2)

Publication Number	Publication Date
IL75887A0 IL75887A0 (en)	1985-12-31
IL75887A true IL75887A (en)	1988-05-31

Family

ID=10564592

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL75887A IL75887A (en)	1984-07-27	1985-07-23	9-substituted-indolo(6,5,4-cd)indole derivatives,their preparation and pharmaceutical compositions containing them

Country Status (7)

Country	Link
US (2)	US4742075A (de)
EP (1)	EP0176182B1 (de)
JP (1)	JPS6143189A (de)
AT (1)	ATE56012T1 (de)
DE (1)	DE3579401D1 (de)
GB (2)	GB8419278D0 (de)
IL (1)	IL75887A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8608893D0 (en) *	1986-04-11	1986-05-14	Erba Farmitalia	D-nor-7-ergoline derivatives
EP3519816A4 (de)	2016-09-29	2020-05-06	The Regents of the University of California	Verbindungen zur erhöhung der neuronalen plastizität
MX2021010198A (es)	2019-02-27	2021-09-21	Univ California	Indoles n-sustituidos y otros heterociclos para el tratamiento de trastornos cerebrales.
KR102946120B1 (ko)	2019-02-27	2026-03-30	더 리젠츠 오브 더 유니버시티 오브 캘리포니아	뇌 장애를 치료하기 위한 아제피노-인돌 및 다른 헤테로사이클
WO2021076572A1 (en) *	2019-10-14	2021-04-22	The Regents Of The University Of California	Ergoline-like compounds for promoting neural plasticity
IL313455A (en)	2021-12-15	2024-08-01	Delix Therapeutics Inc	Phenoxy and benzyloxy modified psychroplastogens and their uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1482871A (en) *	1975-03-18	1977-08-17	Farmaceutici Italia	Tetracyclic indole derivatives
IL57344A (en) *	1978-05-23	1982-05-31	Lilly Industries Ltd	Indolo(4,3-fg)-and indolo(3,4-gh)isoquinolines,their preparation and pharmaceutical compositions containing them
US4201862A (en) *	1979-03-16	1980-05-06	Eli Lilly And Company	2-Azaergolines and 2-aza-8(or 9)-ergolenes
IL59507A (en) *	1979-03-16	1984-01-31	Erba Farmitalia	5-(10-9)abeo-6-methylergoline derivatives,their preparation and pharmaceutical compositions containing them
GB2056437A (en) *	1979-08-07	1981-03-18	Erba Farmitalia	Secoergoline derivatives

1984
- 1984-07-27 GB GB848419278A patent/GB8419278D0/en active Pending
1985
- 1985-07-22 US US06/757,223 patent/US4742075A/en not_active Expired - Fee Related
- 1985-07-23 IL IL75887A patent/IL75887A/xx not_active IP Right Cessation
- 1985-07-23 DE DE8585305218T patent/DE3579401D1/de not_active Expired - Fee Related
- 1985-07-23 EP EP85305218A patent/EP0176182B1/de not_active Expired - Lifetime
- 1985-07-23 AT AT85305218T patent/ATE56012T1/de not_active IP Right Cessation
- 1985-07-23 GB GB8518628A patent/GB2162182B/en not_active Expired
- 1985-07-26 JP JP60165648A patent/JPS6143189A/ja active Pending
1988
- 1988-01-27 US US07/148,807 patent/US4841056A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US4742075A (en)	1988-05-03
JPS6143189A (ja)	1986-03-01
GB8419278D0 (en)	1984-08-30
EP0176182A3 (en)	1986-05-14
DE3579401D1 (de)	1990-10-04
EP0176182A2 (de)	1986-04-02
GB2162182A (en)	1986-01-29
GB2162182B (en)	1989-04-12
US4841056A (en)	1989-06-20
GB8518628D0 (en)	1985-08-29
EP0176182B1 (de)	1990-08-29
ATE56012T1 (de)	1990-09-15
IL75887A0 (en)	1985-12-31

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Legal Events

Date	Code	Title	Description
1996-05-14	RH	Patent void