IL78158A - Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine - Google Patents

Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine

Info

Publication number: IL78158A
Authority: IL; Israel
Prior art keywords: deoxythymidine; azido; pharmaceutical compositions; compositions containing; pharmaceutical
Prior art date: 1985-03-16

Application number

IL78158A

Other languages

English (en)

Other versions

IL78158A0 (en

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-16

Filing date

1986-03-14

Publication date

1988-04-29

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27516579&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL78158(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1985-03-16 Priority claimed from GB858506869A external-priority patent/GB8506869D0/en

1985-05-09 Priority claimed from GB858511774A external-priority patent/GB8511774D0/en

1985-09-17 Priority claimed from US06/776,899 external-priority patent/US4724232A/en

1985-09-27 Priority claimed from GB858523881A external-priority patent/GB8523881D0/en

1986-02-12 Priority claimed from GB868603450A external-priority patent/GB8603450D0/en

1986-03-14 Application filed by Wellcome Found filed Critical Wellcome Found

1986-03-14 Priority to IL85095A priority Critical patent/IL85095A/xx

1986-07-31 Publication of IL78158A0 publication Critical patent/IL78158A0/xx

1988-01-13 Priority to IL85096A priority patent/IL85096A0/xx

1988-01-13 Priority to IL85095A priority patent/IL85095A0/xx

1988-04-29 Publication of IL78158A publication Critical patent/IL78158A/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Virology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Biotechnology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

IL78158A 1985-03-16 1986-03-14 Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine IL78158A (en)

Priority Applications (3)

Application Number	Priority Date	Filing Date	Title
IL85095A IL85095A (en)	1985-05-09	1986-03-14	Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine derivatives,certain such novel compounds and their preparation
IL85096A IL85096A0 (en)	1985-03-16	1988-01-13	Use of 3'-azido-3'-deoxythymidine in the treatment or prophylaxis of human retrovirus infection
IL85095A IL85095A0 (en)	1985-03-16	1988-01-13	Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine derivatives,certain such novel compounds and their preparation

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
GB858506869A GB8506869D0 (en)	1985-03-16	1985-03-16	Antiviral compound
GB858511774A GB8511774D0 (en)	1985-05-09	1985-05-09	Antiviral compounds
US06/776,899 US4724232A (en)	1985-03-16	1985-09-17	Treatment of human viral infections
GB858523881A GB8523881D0 (en)	1985-09-27	1985-09-27	Antiviral compounds
GB868603450A GB8603450D0 (en)	1986-02-12	1986-02-12	Antiviral compounds

Publications (2)

Publication Number	Publication Date
IL78158A0 IL78158A0 (en)	1986-07-31
IL78158A true IL78158A (en)	1988-04-29

Family

ID=27516579

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL78158A IL78158A (en)	1985-03-16	1986-03-14	Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine

Country Status (21)

Country	Link
EP (2)	EP0291633B1 (cs)
JP (1)	JPH0780898B2 (cs)
AP (1)	AP11A (cs)
AT (4)	ATE81978T1 (cs)
AU (1)	AU572019B2 (cs)
CA (1)	CA1238277A (cs)
CS (1)	CS385191A3 (cs)
CY (2)	CY1508A (cs)
DE (4)	DE3687069T2 (cs)
DK (1)	DK164392C (cs)
FI (1)	FI85978C (cs)
GR (1)	GR860712B (cs)
HK (2)	HK85789A (cs)
IE (1)	IE56503B1 (cs)
IL (1)	IL78158A (cs)
MC (1)	MC1742A1 (cs)
MY (1)	MY102693A (cs)
NZ (1)	NZ215486A (cs)
PH (1)	PH24388A (cs)
PT (1)	PT82199B (cs)
SG (1)	SG62889G (cs)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2181128A (en) *	1985-09-17	1987-04-15	Wellcome Found	3'-azidonucleosides
US5077279A (en) *	1986-05-01	1991-12-31	University Of Georgia Research Foundation, Inc.	3'-azido-2',3'-dideoxy-5-methylcytidine anti-viral composition
US5084445A (en) *	1986-05-01	1992-01-28	University Of Georgia Research Foundation, Inc.	3'-azido-2',3'-dideoxy-5-methylcytidine
US4841039A (en) *	1986-05-01	1989-06-20	Emory University	2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents
US4916122A (en) *	1987-01-28	1990-04-10	University Of Georgia Research Foundation, Inc.	3'-Azido-2',3'-dideoxyuridine anti-retroviral composition
US4880782A (en) *	1986-11-21	1989-11-14	Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V.	Method of treating viral infections in humans and compositions therefor
FI892451L (fi) *	1986-11-21	1989-05-19	Max Planck Gesellschaft	Foerfarande med vilket virusinfektioner i maenniskor kan skoetas och kompositioner anvaenda daeri.
SE8605503D0 (sv) *	1986-12-19	1986-12-19	Astra Laekemedel Ab	Novel medicinal use
US5190926A (en) *	1987-01-28	1993-03-02	University Of Georgia Research Foundation, Inc.	3'-azido-2',3'-dideoxypyrimidines and related compounds as antiviral agents
EP0287215B1 (en) *	1987-03-16	1992-06-17	The Wellcome Foundation Limited	Therapeutic nucleosides
EP0282618A1 (en) *	1987-03-18	1988-09-21	Vereniging Het Nederlands Kanker Instituut	1-Deoxynojirimycin as an anti-HIV therapeutic
EP0286825A3 (en) *	1987-03-18	1989-04-12	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.	Use of 3'-fluro-3' deoxythymidine for the manufacture of a medicament for the treatment of virus infections
US4950652A (en) *	1987-03-23	1990-08-21	Hem Research, Inc.	dsRNAs for combination therapy in the treatment of viral diseases
FI881413A7 (fi) *	1987-03-25	1988-09-26	The Wellcome Foundation Ltd	Menetelmä 3'-atsido-3'-deoksitymidiinin valmistamiseksi.
GB8707421D0 (en) *	1987-03-27	1987-04-29	Wellcome Found	Pharmaceutical formulations
IL86007A0 (en) *	1987-04-09	1988-09-30	Wellcome Found	6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
US5185437A (en) *	1987-04-09	1993-02-09	Burroughs Wellcome Co.	Therapeutic nucleosides
IL86009A (en) *	1987-04-10	1991-09-16	Us Health	Liposome-encapsulated phosphorylated nucleosides for treatment of retroviral diseases
US5215970A (en) *	1987-04-16	1993-06-01	Medivir Ab	Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
SE8701605D0 (sv) *	1987-04-16	1987-04-16	Astra Ab	Novel medicinal compounds
DE3868125D1 (de) *	1987-04-24	1992-03-12	Wellcome Found	Antivirale mischungen.
US4863927A (en) *	1987-05-11	1989-09-05	Merck & Co., Inc.	1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils
YU110888A (en) *	1987-06-10	1989-08-31	Wellcome Found	Process for obtaining timine derivatives
USRE33887E (en) *	1987-06-22	1992-04-14	Hoffmann-La Roche Inc.	Anti-retroviral compounds
SU1548182A1 (ru) *	1987-12-29	1990-03-07	Институт молекулярной биологии АН СССР	5 @ -Фосфонаты 3 @ -азидо-2 @ ,3 @ -дидезоксинуклеозидов, вл ющиес специфическими ингибиторами вируса СПИД в культуре лимфоцитов человека Н9/ШВ
US5384396A (en) *	1988-02-23	1995-01-24	The University Of Georgia Research Foundation, Inc.	Process for the deoxygenation of nucleosides
DE3824669C2 (de) *	1988-07-20	1999-05-06	Wondrak Ewald M	Verwendung von Trinatrium-Phosphonoformat
US4987224A (en) *	1988-08-02	1991-01-22	University Of Georgia Research Foundation, Inc.	Method of preparation of 2',3'-dideoxynucleosides
EP0355245A1 (fr) *	1988-08-26	1990-02-28	Michel Vandevelde	Utilisation d'agents d'inhibition de la réverse-transcriptase des rétrovirus
HU205089B (en) *	1989-05-31	1992-03-30	Biogal Gyogyszergyar	Process for producing new thymine derivatives and pharmaceutical compositions comprising same
DK173585B1 (da) *	1989-11-09	2001-04-02	Asta Medica Ag	Anvendelse af alfa-liponsyre til fremstilling af et lægemiddel til bekæmpelse af sygdomme fremkaldt af retrovirus
US5585367A (en) *	1990-04-19	1996-12-17	Previsan S.A.	Method of treating humans and animals infected with viruses of the retrovirus group
WO1991016054A1 (fr) *	1990-04-19	1991-10-31	Previsan S.A.	Derives azoiques, compositions pharmaceutiques et desinfectantes les contenant et leurs utilisations contre le sida
US6812233B1 (en)	1991-03-06	2004-11-02	Emory University	Therapeutic nucleosides
GB9104740D0 (en) *	1991-03-06	1991-04-17	Wellcome Found	Antiviral nucleoside combination
IL102548A (en) *	1991-08-02	1998-08-16	Medivir Ab	Thiourea derivatives for use in the preparation of medicaments for the inhibition of hiv and the treatment of aids and some such novel compounds
US5593993A (en) *	1991-08-02	1997-01-14	Medivir Ab	Method for inhibition of HIV related viruses
US6177435B1 (en)	1992-05-13	2001-01-23	Glaxo Wellcome Inc.	Therapeutic combinations
ATE184787T1 (de) *	1992-05-13	1999-10-15	Wellcome Found	Therapeutische kombinationen
GR920100326A (el) *	1992-07-21	1994-03-31	Medivir Ag	Ενώσεις και μέ?οδοι αναστολής του HIV και των σχετικών ιών.
DE4336640A1 (de) *	1993-10-22	1995-04-27	Deutsches Rheuma Forschungszen	Neue Metallchelate, Verfahren zu deren Herstellung sowie deren Verwendung als antivirale Arzneimittel
CA2270600A1 (en)	1999-05-03	2000-11-03	Infectio Recherche Inc.	Method and formulations for the treatment of diseases, particularly those caused by human immunodeficiency virus and leishmania
HU230248B1 (hu)	2001-10-26	2015-11-30	Msd Italia S.R.L.	N-szubsztituált hidroxipirimidinon-karboxamid HIV-integráz inhibitorok
IL163666A0 (en)	2002-02-22	2005-12-18	New River Pharmaceuticals Inc	Active agent delivery systems and methods for protecting and administering active agents
US8980894B2 (en)	2004-03-25	2015-03-17	Boehringer Ingelheim Vetmedica Gmbh	Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1579862A1 (en)	2004-03-25	2005-09-28	Boehringer Ingelheim Vetmedica Gmbh	Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
PL3021832T3 (pl)	2013-07-19	2021-08-23	Boehringer Ingelheim Vetmedica Gmbh	Konserwowana ciekła wodna kompozycja farmaceutyczna zawierająca eteryfikowane pochodne cyklodekstryny
WO2022008025A1 (en) *	2020-07-05	2022-01-13	Since & Technology Development Fund Authority	2-hydroxyiminopyrimidine nucleosides and derivitives and antiviral uses thereto

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0199451B1 (en) *	1985-03-16	1996-03-06	The Wellcome Foundation Limited	Therapeutic nucleosides

1986
- 1986-03-14 AP APAP/P/1986/000027A patent/AP11A/en active
- 1986-03-14 AT AT88101790T patent/ATE81978T1/de not_active IP Right Cessation
- 1986-03-14 EP EP88101790A patent/EP0291633B1/en not_active Expired - Lifetime
- 1986-03-14 DE DE8888101790T patent/DE3687069T2/de not_active Expired - Lifetime
- 1986-03-14 AT AT0068386A patent/AT390000B/de not_active IP Right Cessation
- 1986-03-14 CY CY1508A patent/CY1508A/xx unknown
- 1986-03-14 DE DE3650130T patent/DE3650130T3/de not_active Expired - Lifetime
- 1986-03-14 MC MC861828A patent/MC1742A1/fr unknown
- 1986-03-14 DK DK118086A patent/DK164392C/da not_active IP Right Cessation
- 1986-03-14 CA CA000504126A patent/CA1238277A/en not_active Expired
- 1986-03-14 IE IE677/86A patent/IE56503B1/en not_active IP Right Cessation
- 1986-03-14 EP EP86301897A patent/EP0196185B1/en not_active Expired
- 1986-03-14 DE DE198686301897T patent/DE196185T1/de active Pending
- 1986-03-14 FI FI861069A patent/FI85978C/fi not_active IP Right Cessation
- 1986-03-14 PH PH33532A patent/PH24388A/en unknown
- 1986-03-14 AU AU54758/86A patent/AU572019B2/en not_active Expired
- 1986-03-14 PT PT82199A patent/PT82199B/pt unknown
- 1986-03-14 NZ NZ215486A patent/NZ215486A/xx unknown
- 1986-03-14 GR GR860712A patent/GR860712B/el unknown
- 1986-03-14 AT AT88101795T patent/ATE113603T1/de not_active IP Right Cessation
- 1986-03-14 AT AT86301897T patent/ATE44464T1/de not_active IP Right Cessation
- 1986-03-14 IL IL78158A patent/IL78158A/xx unknown
- 1986-03-14 DE DE19863608606 patent/DE3608606A1/de not_active Withdrawn
1987
- 1987-09-25 MY MYPI87001943A patent/MY102693A/en unknown
1988
- 1988-03-29 JP JP63073488A patent/JPH0780898B2/ja not_active Expired - Lifetime
1989
- 1989-09-11 SG SG628/89A patent/SG62889G/en unknown
- 1989-10-26 HK HK857/89A patent/HK85789A/en not_active IP Right Cessation
1991
- 1991-12-17 CS CS913851A patent/CS385191A3/cs unknown
1995
- 1995-10-19 HK HK164395A patent/HK164395A/en not_active IP Right Cessation
1996
- 1996-11-22 CY CY188996A patent/CY1889A/xx unknown

Also Published As

Publication number	Publication date
DE3650130T2 (de)	1995-03-16
DK118086A (da)	1986-09-17
ATE44464T1 (de)	1989-07-15
FI85978B (fi)	1992-03-13
HK164395A (en)	1995-10-27
CY1508A (en)	1990-08-03
DK164392C (da)	1992-11-09
ATE81978T1 (de)	1992-11-15
MY102693A (en)	1992-09-30
DE3608606A1 (de)	1986-09-18
AU572019B2 (en)	1988-04-28
ATE113603T1 (de)	1994-11-15
DE3650130T3 (de)	2003-07-24
EP0196185A3 (en)	1988-01-13
CS385191A3 (en)	1992-05-13
AT390000B (de)	1990-02-26
MC1742A1 (fr)	1987-02-26
EP0196185B1 (en)	1989-07-12
HK85789A (en)	1989-11-03
CA1238277A (en)	1988-06-21
FI85978C (fi)	1992-06-25
CY1889A (en)	1996-11-22
AU5475886A (en)	1986-09-18
AP8600027A0 (en)	1986-02-01
EP0291633A1 (en)	1988-11-23
JPS63290895A (ja)	1988-11-28
IE860677L (en)	1986-09-16
AP11A (en)	1987-12-22
DE3687069D1 (de)	1992-12-10
DK118086D0 (da)	1986-03-14
DE3650130D1 (de)	1994-12-08
SG62889G (en)	1990-01-26
FI861069L (fi)	1986-09-17
DE196185T1 (de)	1987-04-30
IE56503B1 (en)	1991-08-14
DK164392B (da)	1992-06-22
NZ215486A (en)	1988-09-29
FI861069A0 (fi)	1986-03-14
ATA68386A (de)	1989-08-15
PT82199A (en)	1986-04-01
DE3687069T2 (de)	1993-03-25
JPH0780898B2 (ja)	1995-08-30
IL78158A0 (en)	1986-07-31
EP0196185A2 (en)	1986-10-01
GR860712B (en)	1986-07-16
PT82199B (pt)	1990-11-07
PH24388A (en)	1990-06-13
EP0291633B1 (en)	1992-11-04

Publication	Publication Date	Title
IL78158A (en)	1988-04-29	Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine
NZ226923A (en)	1990-10-26	5'-deoxy-5-fluorocytidine derivatives and pharmaceutical compositions
IL88670A0 (en)	1989-07-31	2,5-diaryl-tetrahydrofurans and analogs thereof and pharmaceutical compositions containing them
GB2174904B (en)	1989-07-05	Vasculoprotecting pharmaceutical compositions
IL76405A (en)	1990-03-19	1,3-diacyl-2-oxindole derivatives and pharmaceutical compositions containing them
IL74865A (en)	1987-12-31	4'-amino-9a-aza-9a-homoerythromycin derivatives and pharmaceutical compositions containing them
IL80369A (en)	1991-07-18	Insecticidal compositions containing n,n'-diacylhydrazine derivatives and certain such new n,n'-diacylhydrazine derivatives
GB2171600B (en)	1988-08-10	Pharmaceutical compositions
GB8508508D0 (en)	1985-05-09	Pharmaceutical compositions
IL76823A0 (en)	1986-02-28	1,2,4-triazolo-carbamates,their preparation and pharmaceutical compositions containing them
GB8515170D0 (en)	1985-07-17	Pharmaceutical compositions
IL79980A0 (en)	1986-12-31	Pharmaceutical composition containing ypsilon-interferon
GB8607848D0 (en)	1986-04-30	Pharmaceutical compositions
PH23343A (en)	1989-07-14	8 0( acylaminoergolines and pharmaceutical compositions containing them
IL80733A0 (en)	1987-02-27	2,2'-bi-1h-imidazoles and pharmaceutical compositions containing same
SG92592G (en)	1992-12-04	Pharmaceutical compositions containing azanaphthalenes
GB2182561B (en)	1989-12-06	Pharmaceutical compositions
GB8523531D0 (en)	1985-10-30	Pharmaceutical compositions
GB8602601D0 (en)	1986-03-12	Pharmaceutical compositions
GB8522327D0 (en)	1985-10-16	Pharmaceutical compositions
IL85095A0 (en)	1988-06-30	Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine derivatives,certain such novel compounds and their preparation
IL85095A (en)	1991-05-12	Pharmaceutical compositions containing 3'-azido-3'-deoxythymidine derivatives,certain such novel compounds and their preparation
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