IL78455A - Method for purifying recombinant human immune interferon - Google Patents
Method for purifying recombinant human immune interferonInfo
- Publication number
- IL78455A IL78455A IL78455A IL7845586A IL78455A IL 78455 A IL78455 A IL 78455A IL 78455 A IL78455 A IL 78455A IL 7845586 A IL7845586 A IL 7845586A IL 78455 A IL78455 A IL 78455A
- Authority
- IL
- Israel
- Prior art keywords
- human immune
- interferon
- recombinant human
- immune interferon
- purifying recombinant
- Prior art date
Links
- 101000599940 Homo sapiens Interferon gamma Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 108010050904 Interferons Proteins 0.000 abstract 2
- 102000014150 Interferons Human genes 0.000 abstract 2
- 229940079322 interferon Drugs 0.000 abstract 2
- USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 abstract 1
- 239000005695 Ammonium acetate Substances 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 229940043376 ammonium acetate Drugs 0.000 abstract 1
- 235000019257 ammonium acetate Nutrition 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 239000003398 denaturant Substances 0.000 abstract 1
- 238000000502 dialysis Methods 0.000 abstract 1
- 238000010790 dilution Methods 0.000 abstract 1
- 239000012895 dilution Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 239000012264 purified product Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1136—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by reversible modification of the secondary, tertiary or quarternary structure, e.g. using denaturating or stabilising agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/57—IFN-gamma
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
- Y10S930/142—Interferon
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/727,147 US4873312A (en) | 1985-04-25 | 1985-04-25 | Method for purifying interferon and composition of matter produced thereby |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL78455A0 IL78455A0 (en) | 1986-08-31 |
| IL78455A true IL78455A (en) | 1991-11-21 |
Family
ID=24921509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL78455A IL78455A (en) | 1985-04-25 | 1986-04-09 | Method for purifying recombinant human immune interferon |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4873312A (de) |
| EP (1) | EP0199568B1 (de) |
| JP (1) | JPH0733397B2 (de) |
| AT (1) | ATE86868T1 (de) |
| CA (1) | CA1263842A (de) |
| DE (1) | DE3687995T2 (de) |
| IL (1) | IL78455A (de) |
| WO (1) | WO1986006385A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1339757C (en) | 1987-04-16 | 1998-03-17 | Robert F. Halenbeck | Production of purified biologically active, bacterially produced recombinant human csf-1 |
| US4929700A (en) * | 1987-04-16 | 1990-05-29 | Cetus Corporation | Production of purified, biologically active, bacterially produced recombinant human CSF-1 |
| US4931543A (en) * | 1987-05-11 | 1990-06-05 | Cetus Corporation | Process for recovering microbially produced interleukin-2 |
| US5599690A (en) * | 1988-02-01 | 1997-02-04 | Amgen Inc. | Control of norleucine incorporation into recombinant proteins |
| US5391713A (en) * | 1989-06-20 | 1995-02-21 | Bionative Ab | Interferon purification process |
| DE3926103A1 (de) * | 1989-08-08 | 1991-02-14 | Hoechst Ag | Verfahren zur biokatalytischen korrekten kettenfaltung denaturierter rekombinanter fusionsproteine |
| DK580789D0 (da) * | 1989-11-20 | 1989-11-20 | Novo Nordisk As | Fremgangsmaade til oprensning af polypeptider |
| US5986070A (en) * | 1990-04-06 | 1999-11-16 | Amgen Inc. | Production of biologically active NGF proteins |
| IT1246296B (it) * | 1990-07-25 | 1994-11-17 | Sclavo Spa | Procedimento di estrzione e purificazione del gamma interferone umano ricombinante |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5821691A (ja) * | 1981-07-29 | 1983-02-08 | Mochida Pharmaceut Co Ltd | α−及びβ−インタ−フェロンの精製方法 |
| AU561343B2 (en) * | 1981-10-19 | 1987-05-07 | Genentech Inc. | Human immune interferon by recombinant dna |
| US6936694B1 (en) * | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
| WO1984002129A1 (fr) * | 1982-11-22 | 1984-06-07 | Takeda Chemical Industries Ltd | Proteine de l'interferon immun humain et son procede de preparation |
| US4518526A (en) * | 1982-12-22 | 1985-05-21 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| JPH06102034B2 (ja) * | 1983-03-25 | 1994-12-14 | セルテク リミテツド | タンパク質の生産方法 |
| US4476049A (en) * | 1983-09-20 | 1984-10-09 | Hoffmann-La Roche Inc. | Method for the extraction of immune interferon |
| JPS6079000A (ja) * | 1983-10-04 | 1985-05-04 | Takeda Chem Ind Ltd | ヒトγ型インタ−フエロン単量体の製造法 |
| US4855238A (en) * | 1983-12-16 | 1989-08-08 | Genentech, Inc. | Recombinant gamma interferons having enhanced stability and methods therefor |
-
1985
- 1985-04-25 US US06/727,147 patent/US4873312A/en not_active Expired - Fee Related
-
1986
- 1986-04-04 CA CA000505897A patent/CA1263842A/en not_active Expired
- 1986-04-09 JP JP61502079A patent/JPH0733397B2/ja not_active Expired - Lifetime
- 1986-04-09 IL IL78455A patent/IL78455A/xx not_active IP Right Cessation
- 1986-04-09 WO PCT/US1986/000723 patent/WO1986006385A1/en not_active Ceased
- 1986-04-18 AT AT86302960T patent/ATE86868T1/de not_active IP Right Cessation
- 1986-04-18 DE DE8686302960T patent/DE3687995T2/de not_active Revoked
- 1986-04-18 EP EP86302960A patent/EP0199568B1/de not_active Revoked
Also Published As
| Publication number | Publication date |
|---|---|
| CA1263842A (en) | 1989-12-12 |
| ATE86868T1 (de) | 1993-04-15 |
| JPS62502540A (ja) | 1987-10-01 |
| WO1986006385A1 (en) | 1986-11-06 |
| IL78455A0 (en) | 1986-08-31 |
| EP0199568A2 (de) | 1986-10-29 |
| EP0199568B1 (de) | 1993-03-17 |
| DE3687995D1 (de) | 1993-04-22 |
| DE3687995T2 (de) | 1993-06-24 |
| EP0199568A3 (en) | 1988-09-21 |
| US4873312A (en) | 1989-10-10 |
| JPH0733397B2 (ja) | 1995-04-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| RH | Patent void |