IL79168A0 - Prostacyclins,their preparation and pharmaceutical compositions containing them - Google Patents

Prostacyclins,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL79168A0
Authority: IL; Israel
Prior art keywords: prostacyclins; preparation; pharmaceutical compositions; compositions containing; hydrogen
Prior art date: 1985-06-24

Application number

IL79168A

Other languages

English (en)

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-06-24

Filing date

1986-06-19

Publication date

1986-09-30

1986-06-19 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1986-09-30 Publication of IL79168A0 publication Critical patent/IL79168A0/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
150000003815 prostacyclins Chemical class 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000001153 fluoro group Chemical group F* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
230000002744 anti-aggregatory effect Effects 0.000 abstract 1
210000001772 blood platelet Anatomy 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Hematology (AREA)
Diabetes (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Furan Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Epoxy Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

IL79168A 1985-06-24 1986-06-19 Prostacyclins,their preparation and pharmaceutical compositions containing them IL79168A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/747,740 US4634782A (en)	1985-06-24	1985-06-24	7-fluoro-dihydro PGI compounds

Publications (1)

Publication Number	Publication Date
IL79168A0 true IL79168A0 (en)	1986-09-30

Family

ID=25006425

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL79168A IL79168A0 (en)	1985-06-24	1986-06-19	Prostacyclins,their preparation and pharmaceutical compositions containing them

Country Status (11)

Country	Link
US (1)	US4634782A (da)
EP (1)	EP0209694B1 (da)
JP (1)	JPS62482A (da)
AT (1)	ATE45575T1 (da)
AU (1)	AU595533B2 (da)
DE (1)	DE3665063D1 (da)
DK (1)	DK295586A (da)
IL (1)	IL79168A0 (da)
NZ (1)	NZ216613A (da)
PH (1)	PH24217A (da)
ZA (1)	ZA864590B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS59227888A (ja) *	1983-06-10	1984-12-21	Asahi Glass Co Ltd	７−フルオロプロスタグランジン類の製造方法
US4808734A (en) *	1986-12-01	1989-02-28	Hoffmann-La Roche Inc.	16-cycloalkyl-7-fluoro-prostacyclins
CH674363A5 (da) *	1986-12-01	1990-05-31	Hoffmann La Roche
DE69502517T2 (de) *	1994-02-17	1998-10-01	Asahi Glass Co Ltd	Difluorprostacycline, Zwischenprodukte und Verfahren zu deren Herstellung

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6570680A (en) *	1979-10-10	1981-04-28	University Of Chicago, The	Chemical synthesis
GB2088856B (en) *	1980-10-27	1984-06-27	Chinoin Gyogyszer Es Vegyeszet	7-substituted pg12-derivatives their preparation and pharmaceutical compositions containing them
US4472428A (en) *	1980-12-09	1984-09-18	Teijin Limited	Halogenated prostacyclins pharmaceutical use thereof and hydroxy intermediates therefore
US4558142A (en) *	1981-03-11	1985-12-10	Hoffmann-La Roche Inc.	7-Fluoro-prostacyclin analogs
CH651033A5 (de) *	1981-03-11	1985-08-30	Hoffmann La Roche	Fluorprostacycline.
JPS59227888A (ja) *	1983-06-10	1984-12-21	Asahi Glass Co Ltd	７−フルオロプロスタグランジン類の製造方法

1985
- 1985-06-24 US US06/747,740 patent/US4634782A/en not_active Expired - Fee Related
1986
- 1986-06-06 EP EP86107750A patent/EP0209694B1/en not_active Expired
- 1986-06-06 DE DE8686107750T patent/DE3665063D1/de not_active Expired
- 1986-06-06 AT AT86107750T patent/ATE45575T1/de active
- 1986-06-19 IL IL79168A patent/IL79168A0/xx unknown
- 1986-06-19 ZA ZA864590A patent/ZA864590B/xx unknown
- 1986-06-20 NZ NZ216613A patent/NZ216613A/xx unknown
- 1986-06-20 PH PH33921A patent/PH24217A/en unknown
- 1986-06-23 AU AU59204/86A patent/AU595533B2/en not_active Expired - Fee Related
- 1986-06-23 DK DK295586A patent/DK295586A/da not_active Application Discontinuation
- 1986-06-24 JP JP61147984A patent/JPS62482A/ja active Pending

Also Published As

Publication number	Publication date
AU595533B2 (en)	1990-04-05
AU5920486A (en)	1987-01-08
PH24217A (en)	1990-04-10
US4634782A (en)	1987-01-06
DK295586A (da)	1986-12-25
JPS62482A (ja)	1987-01-06
ATE45575T1 (de)	1989-09-15
EP0209694A1 (en)	1987-01-28
EP0209694B1 (en)	1989-08-16
DK295586D0 (da)	1986-06-23
ZA864590B (en)	1987-02-25
NZ216613A (en)	1989-04-26
DE3665063D1 (en)	1989-09-21

Publication	Publication Date	Title
ZA882418B (en)	1989-12-27	1-phenyl-3-naphthalenyloxypropanamines
FI850140A0 (fi)	1985-01-11	Kemiska foereningar.
SE8601907D0 (sv)	1986-04-24	Imidazoquinoline antithrombogenic cardiotonic agents
NO306510B1 (no)	1999-11-15	Androsteroner, anvendelse derav og farmasöytisk formulering
FI844333A0 (fi)	1984-11-05	11-substituerade 5h,11h-pyrrolo/2,1-c/ /1,4/benzoxazepiner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
DE3879258D1 (de)	1993-04-22	Praeparat gegen ulcus.
IL79168A0 (en)	1986-09-30	Prostacyclins,their preparation and pharmaceutical compositions containing them
IL78954A0 (en)	1986-09-30	Spiro-imidazolidines and pharmaceutical compositions containing them
SE8703023D0 (sv)	1987-07-31	Mellanprodukter for framstellning av fluorprostacykliner
ATE106734T1 (de)	1994-06-15	Pharmazeutische zusammensetzung zur verhinderung der plättchenaggregation.
DE3272896D1 (en)	1986-10-02	Aminocyclopentane esters and their preparation and pharmaceutical formulation
IL70630A (en)	1986-12-31	Triazolopyridoquinazolinones,analogs thereof,their preparation and pharmaceutical compositions containing them
ES2036722T3 (es)	1993-06-01	Un procedimiento para preparar una composicion farmaceutica que contiene un agente estabilizador.