IL79193A0 - (4-piperidinylmethyl and-hetero)purines,their preparation and pharmaceutical compositions containing them - Google Patents

(4-piperidinylmethyl and-hetero)purines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL79193A0
IL79193A0 IL79193A IL7919386A IL79193A0 IL 79193 A0 IL79193 A0 IL 79193A0 IL 79193 A IL79193 A IL 79193A IL 7919386 A IL7919386 A IL 7919386A IL 79193 A0 IL79193 A0 IL 79193A0
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
piperidinylmethyl
purines
hetero
compositions containing
Prior art date
Application number
IL79193A
Other languages
English (en)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL79193A0 publication Critical patent/IL79193A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL79193A 1985-06-24 1986-06-23 (4-piperidinylmethyl and-hetero)purines,their preparation and pharmaceutical compositions containing them IL79193A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858515934A GB8515934D0 (en) 1985-06-24 1985-06-24 (4-piperidinomethyl and-hetero)purines

Publications (1)

Publication Number Publication Date
IL79193A0 true IL79193A0 (en) 1986-09-30

Family

ID=10581240

Family Applications (1)

Application Number Title Priority Date Filing Date
IL79193A IL79193A0 (en) 1985-06-24 1986-06-23 (4-piperidinylmethyl and-hetero)purines,their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (1) US5041448A (da)
EP (1) EP0206415B1 (da)
JP (1) JPS62487A (da)
KR (1) KR930009356B1 (da)
AT (1) ATE85055T1 (da)
AU (1) AU588890B2 (da)
CA (1) CA1267889A (da)
DE (1) DE3687601T2 (da)
DK (1) DK169073B1 (da)
ES (1) ES8800682A1 (da)
FI (1) FI85704C (da)
GB (1) GB8515934D0 (da)
GR (1) GR861580B (da)
HU (1) HU199143B (da)
IE (1) IE59658B1 (da)
IL (1) IL79193A0 (da)
NO (1) NO163956C (da)
NZ (1) NZ216536A (da)
PT (1) PT82824B (da)
SU (1) SU1581221A3 (da)
ZA (1) ZA864677B (da)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
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US5151424A (en) * 1987-07-01 1992-09-29 Janssen Pharmaceutica N.V. Pharmacologically active (Bicyclic heterocyclyl)methyl and -hetero) substituted hexahydro-1H-azepines and pyrrolidines
US4988689A (en) * 1987-07-01 1991-01-29 Janssen Pharmaceutica N.V. ((Pharmacologically active bicyclic heterocyclic)methyl and -heteroatom) substituted hexahydro-1H-azepines and pyrrolidines
CA1317939C (en) * 1987-07-01 1993-05-18 Janssen Pharmaceutica Naamloze Vennootschap ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines
GB8716313D0 (en) * 1987-07-10 1987-08-19 Janssen Pharmaceutica Nv 2-(heterocyclylalkyl)imidazopyridines
GB8900380D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
US5272150A (en) * 1989-04-07 1993-12-21 Janssen Pharmaceutica N.V. Hydroxyalkylfuranyl derivatives
NZ238863A (en) * 1990-07-19 1993-03-26 Janssen Pharmaceutica Nv Substituted thiazolyl and pyridinyl derivatives
US5360807A (en) * 1990-07-19 1994-11-01 Janssen Pharmaceutica N.V. Substituted thiazolyl and substituted pyridinyl derivatives
KR100190299B1 (ko) * 1990-07-19 1999-06-01 디르크 반테 신규한 옥사졸릴 유도체
US5217980A (en) * 1990-07-19 1993-06-08 Janssen Pharmaceutica N.V. Oxazolyl and piperidinyl substituted benimidazolyl compounds
WO1992006086A1 (en) * 1990-10-01 1992-04-16 Janssen Pharmaceutica N.V. Novel 4-piperidinylcarbonyl derivatives
US5521183A (en) * 1994-08-30 1996-05-28 Allergan Use of 5-HT ligands as anti-pruritic agents
BR9712792A (pt) * 1996-08-28 1999-12-14 Procter & Gamble Inibidores de metaloprotease bidentada.
KR100239800B1 (ko) * 1996-11-28 2000-03-02 손경식 4,5-디아미노 피리미딘 유도체 및 이의 제조방법
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US7495005B2 (en) * 2002-08-22 2009-02-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Xanthine derivatives, their preparation and their use in pharmaceutical compositions
US7569574B2 (en) * 2002-08-22 2009-08-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Purine derivatives, the preparation thereof and their use as pharmaceutical compositions
DE10238477A1 (de) * 2002-08-22 2004-03-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Purinderivate, deren Herstellung und deren Verwendung als Arzneimittel
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US7501426B2 (en) * 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004009039A1 (de) * 2004-02-23 2005-09-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-[3-Amino-piperidin-1-yl]-xanthine, deren Herstellung und Verwendung als Arzneimittel
US7393847B2 (en) 2004-03-13 2008-07-01 Boehringer Ingleheim International Gmbh Imidazopyridazinediones, their preparation and their use as pharmaceutical compositions
US7179809B2 (en) * 2004-04-10 2007-02-20 Boehringer Ingelheim International Gmbh 2-Amino-imidazo[4,5-d]pyridazin-4-ones, their preparation and their use as pharmaceutical compositions
US7439370B2 (en) * 2004-05-10 2008-10-21 Boehringer Ingelheim International Gmbh Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides
DE102004030502A1 (de) 2004-06-24 2006-01-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Imidazole und Triazole, deren Herstellung und Verwendung als Arzneimittel
DE102004043944A1 (de) * 2004-09-11 2006-03-30 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 8-(3-Amino-piperidin-1-yl)-7-(but-2-inyl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
DE102004044221A1 (de) * 2004-09-14 2006-03-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 3-Methyl-7-butinyl-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
DE102004054054A1 (de) * 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
MX2007011903A (es) * 2005-03-30 2007-12-05 Conforma Therapeutics Corp Alquinil pirrolopirimidinas y analogos relacionados como inhibidores de hsp90.
DE102005035891A1 (de) * 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
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CN109503584A (zh) * 2006-05-04 2019-03-22 勃林格殷格翰国际有限公司 多晶型
JP2010500326A (ja) * 2006-08-08 2010-01-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糖尿病の治療のためのｄｐｐ−ｉｖ阻害剤としてのピロロ［３，２−ｄ］ピリミジン
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PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
ES2764251T3 (es) * 2008-08-15 2020-06-02 Boehringer Ingelheim Int Inhibidores de DPP-4 para uso en el tratamiento de curación de heridas en pacientes diabéticos
WO2010029089A2 (en) 2008-09-10 2010-03-18 Boehringer Ingelheim International Gmbh Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
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CH593954A5 (da) * 1975-07-21 1977-12-30 Ciba Geigy Ag
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US4556660A (en) * 1982-07-12 1985-12-03 Janssen Pharmaceutica N.V. N-(Bicyclic heterocyclyl)-4-piperidinamines
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
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Also Published As

Publication number Publication date
ES556381A0 (es) 1987-11-16
SU1581221A3 (ru) 1990-07-23
EP0206415B1 (en) 1993-01-27
US5041448A (en) 1991-08-20
GR861580B (en) 1986-10-21
NO163956C (no) 1990-08-15
FI85704B (fi) 1992-02-14
GB8515934D0 (en) 1985-07-24
AU5919186A (en) 1987-01-08
ZA864677B (en) 1988-02-24
DK295286A (da) 1986-12-25
JPS62487A (ja) 1987-01-06
NO862504L (no) 1986-12-29
FI862655A0 (fi) 1986-06-23
IE861674L (en) 1986-12-24
AU588890B2 (en) 1989-09-28
HUT42095A (en) 1987-06-29
CA1267889A (en) 1990-04-17
KR870000335A (ko) 1987-02-17
FI85704C (fi) 1992-05-25
DE3687601T2 (de) 1993-06-03
ATE85055T1 (de) 1993-02-15
NO862504D0 (no) 1986-06-23
PT82824B (pt) 1988-07-29
DK169073B1 (da) 1994-08-08
HU199143B (en) 1990-01-29
NZ216536A (en) 1988-10-28
PT82824A (en) 1986-07-01
EP0206415A3 (en) 1988-03-16
FI862655A7 (fi) 1986-12-25
EP0206415A2 (en) 1986-12-30
NO163956B (no) 1990-05-07
DK295286D0 (da) 1986-06-23
IE59658B1 (en) 1994-03-09
KR930009356B1 (ko) 1993-09-28
ES8800682A1 (es) 1987-11-16
DE3687601D1 (de) 1993-03-11

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