IL81201A - Indole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

Indole derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL81201A
Authority: IL; Israel
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; indole derivatives; indole
Prior art date: 1986-01-08

Application number

IL81201A

Other languages

English (en)

Other versions

IL81201A0 (en

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-08

Filing date

1987-01-08

Publication date

1991-06-10

1987-01-08 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1987-08-31 Publication of IL81201A0 publication Critical patent/IL81201A0/xx

1991-06-10 Publication of IL81201A publication Critical patent/IL81201A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IL81201A 1986-01-08 1987-01-08 Indole derivatives,their preparation and pharmaceutical compositions containing them IL81201A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868600397A GB8600397D0 (en)	1986-01-08	1986-01-08	Chemical compounds

Publications (2)

Publication Number	Publication Date
IL81201A0 IL81201A0 (en)	1987-08-31
IL81201A true IL81201A (en)	1991-06-10

Family

ID=10591074

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL81201A IL81201A (en)	1986-01-08	1987-01-08	Indole derivatives,their preparation and pharmaceutical compositions containing them

Country Status (23)

Country	Link
US (1)	US4855314A (2)
EP (1)	EP0240096A1 (2)
JP (1)	JPS62228056A (2)
KR (1)	KR870007116A (2)
CN (1)	CN1030409A (2)
AU (1)	AU597325B2 (2)
BE (1)	BE1000071A4 (2)
CH (1)	CH672637A5 (2)
DE (1)	DE3700408A1 (2)
DK (1)	DK8787A (2)
FI (1)	FI870062A7 (2)
FR (1)	FR2595351B1 (2)
GB (2)	GB8600397D0 (2)
HU (1)	HU198685B (2)
IL (1)	IL81201A (2)
IT (1)	IT1205849B (2)
LU (1)	LU86732A1 (2)
NL (1)	NL8700026A (2)
NO (1)	NO870075L (2)
NZ (1)	NZ218868A (2)
PH (1)	PH24741A (2)
PT (1)	PT84075B (2)
ZA (1)	ZA87105B (2)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8530507D0 (en) *	1985-12-11	1986-01-22	Glaxo Group Plc	Chemical compounds
GB8600398D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds
US5225431A (en) *	1987-10-23	1993-07-06	Burroughs Wellcome Co.	Therapeutic substituted indole compounds and compositions thereof
GB8724912D0 (en)	1987-10-23	1987-11-25	Wellcome Found	Indole derivatives
GB8819024D0 (en) *	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
GB8823731D0 (en) *	1988-10-10	1988-11-16	Smith Kline French Lab	Biologically active compounds
CZ288351B6 (en) *	1990-06-07	2001-05-16	Astrazeneca Ab	Nitrogenous heterocyclic compound, process of its preparation and use as well as a medicament containing thereof
US5559246A (en) *	1990-10-15	1996-09-24	Pfizer Inc.	Indole derivatives
US5545644A (en) *	1990-10-15	1996-08-13	Pfizer Inc.	Indole derivatives
HU225055B1 (en) *	1990-10-15	2006-05-29	Pfizer	Indole derivatives, their intermediates, process for production them and pharmaceutical compositions containing the compounds
US5559129A (en) *	1990-10-15	1996-09-24	Pfizer Inc	Indole derivatives
US5607951A (en) *	1990-10-15	1997-03-04	Pfizer Inc	Indole derivatives
US5578612A (en) *	1990-10-15	1996-11-26	Pfizer Inc.	Indole derivatives
CA2061520C (en) *	1991-03-27	2003-04-22	Lawrence J. Daher	Delivery system for enhanced onset and increased potency
CA2124206C (en) *	1991-11-25	2001-02-27	John Eugene Macor	Indole derivatives
TW288010B (2) *	1992-03-05	1996-10-11	Pfizer
AU670579B2 (en)	1992-04-07	1996-07-25	Pfizer Inc.	Indole derivatives as 5-HT1 agonists
US6380233B1 (en)	1992-04-07	2002-04-30	Pfizer Inc	Indole derivatives as 5-HT1 agonists
GB9207930D0 (en) *	1992-04-10	1992-05-27	Pfizer Ltd	Indoles
EP0635015B1 (en) *	1992-04-10	1997-01-29	Pfizer Inc.	Acylaminoindole derivatives as 5-ht1 agonists
GB9211277D0 (en)	1992-05-28	1992-07-15	Glaxo Group Inc	Pharmaceutical compositions
TW251284B (2) *	1992-11-02	1995-07-11	Pfizer
FR2707639B1 (fr) *	1993-06-30	1995-10-13	Pf Medicament	Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
ES2070772B1 (es) *	1993-08-09	1996-02-16	Pfizer	Derivados de acilaminoindol
AU686654B2 (en) *	1993-08-31	1998-02-12	Pfizer Inc.	5-arylindole derivatives
US5468768A (en) *	1994-01-06	1995-11-21	Bristol-Myers Squibb Company	Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en)	1994-08-27	1994-10-19	Pfizer Ltd	Therapeutic agents
FR2749846B1 (fr) *	1996-06-17	1998-09-11	Pf Medicament	Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US7189753B1 (en)	1997-11-06	2007-03-13	Cady Roger K	Preemptive prophylaxis of migraine
US5994352A (en) *	1998-11-13	1999-11-30	Pfizer Inc.	5-arylindole derivatives
EP1311478B1 (en) *	2000-08-21	2006-06-07	Pacific Corporation	Novel (thio)urea compounds and the pharmaceutical compositions containing the same
SI1517909T1 (sl)	2002-06-21	2007-06-30	Suven Life Sciences Ltd	Novi tetraciklični arilkarbonil indoli, ki imajo afiniteto za serotoninski receptor, uporabni kot terapevtska sredstva, postopek za njihovo pripravo in farmacevtski sestavki, ki jih vsebujejo
ES2297216T3 (es) *	2002-06-21	2008-05-01	Suven Life Sciences Limited	Indoles tetraciclicos arilsulfonil que tienen afinidad con el receptor de la serotonina.
BR0312175A (pt) *	2002-06-21	2005-04-05	Suven Life Sciences Ltd	Composto, composição farmacêutica, uso de um composto, método para o tratamento e método para reduzir a morbidez e a mortalidade associadas com o excesso de peso
US7507835B2 (en)	2002-11-28	2009-03-24	Suven Life Sciences Ltd.	N-arylsulfonyl-3-aminoalkoxyindoles
ATE401307T1 (de) *	2002-11-28	2008-08-15	Suven Life Sciences Ltd	N-arylsulfonyl-2-substituierte indole mit affinität zum serotonin rezeptor, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
JP4571507B2 (ja) *	2002-12-18	2010-10-27	スベンライフサイエンシズリミティド	セロトニン受容体親和性を有する四環系３−置換インドール
CA2508290C (en) *	2002-12-20	2017-02-28	Ciba Specialty Chemicals Holding Inc.	Synthesis of amines and intermediates for the synthesis thereof
AU2007257882B2 (en)	2006-06-12	2011-09-08	Secura Bio Inc.	Process for making salts of N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3472870A (en) *	1966-08-29	1969-10-14	Mead Johnson & Co	Sulfonamidotryptamines
FR2334358A1 (fr) *	1975-12-12	1977-07-08	Sogeras	Nouveaux medicaments derives de l'indole
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
ZW19381A1 (en) *	1980-08-12	1983-03-09	Glaxo Group Ltd	Heterocyclic compounds
DK157995C (da) *	1980-08-12	1990-08-06	Glaxo Group Ltd	Analogifremgangsmaade til fremstilling af indolderivater
GB8332437D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Chemical compounds
GB8332435D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Chemical compounds
GB8332434D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Production of chemical compounds
GB8600398D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds

1986
- 1986-01-08 GB GB868600397A patent/GB8600397D0/en active Pending
1987
- 1987-01-08 CH CH45/87A patent/CH672637A5/fr not_active IP Right Cessation
- 1987-01-08 GB GB8700382A patent/GB2185020B/en not_active Expired - Fee Related
- 1987-01-08 PT PT84075A patent/PT84075B/pt not_active IP Right Cessation
- 1987-01-08 DE DE19873700408 patent/DE3700408A1/de not_active Withdrawn
- 1987-01-08 PH PH34698A patent/PH24741A/en unknown
- 1987-01-08 NL NL8700026A patent/NL8700026A/nl not_active Application Discontinuation
- 1987-01-08 DK DK008787A patent/DK8787A/da unknown
- 1987-01-08 FI FI870062A patent/FI870062A7/fi not_active Application Discontinuation
- 1987-01-08 AU AU67420/87A patent/AU597325B2/en not_active Ceased
- 1987-01-08 LU LU86732A patent/LU86732A1/fr unknown
- 1987-01-08 ZA ZA87105A patent/ZA87105B/xx unknown
- 1987-01-08 IL IL81201A patent/IL81201A/xx unknown
- 1987-01-08 JP JP62002589A patent/JPS62228056A/ja active Pending
- 1987-01-08 NO NO870075A patent/NO870075L/no unknown
- 1987-01-08 EP EP87300166A patent/EP0240096A1/en not_active Withdrawn
- 1987-01-08 US US07/001,469 patent/US4855314A/en not_active Expired - Lifetime
- 1987-01-08 BE BE8700003A patent/BE1000071A4/fr not_active IP Right Cessation
- 1987-01-08 NZ NZ218868A patent/NZ218868A/xx unknown
- 1987-01-08 KR KR870000068A patent/KR870007116A/ko not_active Withdrawn
- 1987-01-08 FR FR878700107A patent/FR2595351B1/fr not_active Expired - Fee Related
- 1987-01-08 IT IT47507/87A patent/IT1205849B/it active
- 1987-07-03 HU HU873020A patent/HU198685B/hu not_active IP Right Cessation
- 1987-07-06 CN CN87105335A patent/CN1030409A/zh active Pending

Also Published As

Publication number	Publication date
IT1205849B (it)	1989-03-31
GB8600397D0 (en)	1986-02-12
PH24741A (en)	1990-10-01
EP0240096A1 (en)	1987-10-07
NO870075D0 (no)	1987-01-08
GB2185020A (en)	1987-07-08
US4855314A (en)	1989-08-08
KR870007116A (ko)	1987-08-14
IL81201A0 (en)	1987-08-31
CN1030409A (zh)	1989-01-18
IT8747507A0 (it)	1987-01-08
FR2595351A1 (fr)	1987-09-11
GB8700382D0 (en)	1987-02-11
FR2595351B1 (fr)	1990-07-13
JPS62228056A (ja)	1987-10-06
NZ218868A (en)	1990-04-26
DE3700408A1 (de)	1987-07-09
PT84075A (en)	1987-02-01
ZA87105B (en)	1987-09-30
NL8700026A (nl)	1987-08-03
FI870062A0 (fi)	1987-01-08
CH672637A5 (2)	1989-12-15
GB2185020B (en)	1990-05-16
PT84075B (pt)	1989-07-31
HU198685B (en)	1989-11-28
HUT46891A (en)	1988-12-28
LU86732A1 (fr)	1988-02-02
FI870062A7 (fi)	1987-07-09
NO870075L (no)	1987-07-09
DK8787A (da)	1987-07-09
DK8787D0 (da)	1987-01-08
AU597325B2 (en)	1990-05-31
AU6742087A (en)	1987-07-09
BE1000071A4 (fr)	1988-02-02

Publication	Publication Date	Title
IL81201A0 (en)	1987-08-31	Indole derivatives,their preparation and pharmaceutical compositions containing them
IL86877A0 (en)	1988-11-30	Indole derivatives,their preparation and pharmaceutical compositions containing them
IL96385A0 (en)	1991-08-16	Indole derivatives,their preparation and pharmaceutical compositions containing them
IL73756A0 (en)	1985-03-31	Indole derivatives,their preparation and pharmaceutical compositions containing them
IL82246A0 (en)	1987-10-30	Quinoline derivatives,their preparation and pharmaceutical compositions containing them
IL80296A (en)	1990-06-10	Phenylpyridone derivatives,their preparation and pharmaceutical compositions containing them
LTIP915A (en)	1995-03-27	Catehol derivatives,methods for their preparation and pharmaceutical compositions containing them
IL89205A (en)	1993-04-04	Chloroaniline derivatives, their preparation and pharmaceutical compositions containing them
IL83432A (en)	1992-06-21	N-phenylcarboxamide derivatives,their preparation and pharmaceutical compositions containing them
IL79401A (en)	1991-05-12	Distamycin derivatives,their preparation and pharmaceutical compositions containing them
NZ219624A (en)	1988-11-29	Indole derivatives and pharmaceutical compositions
IL84098A0 (en)	1988-03-31	Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL80336A (en)	1990-02-09	Indole or benzopyrazole derivatives,their preparation and pharmaceutical compositions containing them
IL79402A0 (en)	1986-10-31	Poly-4-aminopyrrole-2-carboxamido derivatives,their preparation and pharmaceutical compositions containing them
IL84380A0 (en)	1988-04-29	Dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL66223A0 (en)	1982-11-30	Indole derivatives,their preparation and pharmaceutical compositions containing them
IL84554A0 (en)	1988-04-29	Imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL84128A (en)	1992-12-01	3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
AU6741887A (en)	1987-07-09	Indole derivatives, processes for their preparation and pharmaceutical compositions containing them
IL81858A0 (en)	1987-10-20	Acetamide derivatives,their preparation and pharmaceutical compositions containing them
DE3572977D1 (en)	1989-10-19	Indole derivatives, their preparation, their use as medicines and compositions containing them
IL82860A0 (en)	1987-12-20	Dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
IL84636A0 (en)	1988-04-29	Lactam derivatives,their preparation and pharmaceutical compositions containing them
IL83753A (en)	1991-07-18	Sulphonamidoethyl derivatives,their preparation and pharmaceutical compositions containing them
EP0159652A3 (en)	1986-09-03	4-phenylphthalazine derivatives, their preparation and pharmaceutical compositions containing them