IL85627A - Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts - Google Patents
Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its saltsInfo
- Publication number
- IL85627A IL85627A IL85627A IL8562788A IL85627A IL 85627 A IL85627 A IL 85627A IL 85627 A IL85627 A IL 85627A IL 8562788 A IL8562788 A IL 8562788A IL 85627 A IL85627 A IL 85627A
- Authority
- IL
- Israel
- Prior art keywords
- metformin
- salts
- treatment
- disorders
- pharmaceutical compositions
- Prior art date
Links
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003105 metformin Drugs 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000035475 disorder Diseases 0.000 title 1
- 230000000302 ischemic effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 3
- 206010029113 Neovascularisation Diseases 0.000 abstract 1
- 230000000496 anti-anoxic effect Effects 0.000 abstract 1
- 230000002253 anti-ischaemic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8703028A FR2611500B1 (fr) | 1987-03-06 | 1987-03-06 | Emploi de derives du biguanide dans la preparation de medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL85627A0 IL85627A0 (en) | 1988-08-31 |
| IL85627A true IL85627A (en) | 1993-01-14 |
Family
ID=9348653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL85627A IL85627A (en) | 1987-03-06 | 1988-03-03 | Pharmaceutical compositions for treatment of disorders of ischemic origin comprising metformin and its salts |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0283369B1 (de) |
| JP (1) | JPH0818978B2 (de) |
| AT (1) | ATE98120T1 (de) |
| AU (1) | AU610134B2 (de) |
| CA (1) | CA1328606C (de) |
| DE (1) | DE3886075T2 (de) |
| DK (1) | DK169713B1 (de) |
| FR (1) | FR2611500B1 (de) |
| IL (1) | IL85627A (de) |
| ZA (1) | ZA881540B (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5100919A (en) * | 1984-03-19 | 1992-03-31 | The Rockefeller University | Biguanides and derivatives thereof as inhibitors of advanced glycosylation of a target protein |
| AU651571B2 (en) * | 1990-02-09 | 1994-07-28 | Pharmacia & Upjohn Company | Use of insulin sensitizing agents to treat hypertension |
| US5356913A (en) * | 1990-02-09 | 1994-10-18 | The Upjohn Company | Use of insulin sensitizing agents to treat hypertension |
| DE4432757A1 (de) * | 1994-09-14 | 1996-03-21 | Boehringer Mannheim Gmbh | Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung |
| WO1996008262A1 (en) * | 1994-09-15 | 1996-03-21 | Pharmagenesis, Inc. | Composition and method for immunotherapy |
| EP1039890B1 (de) * | 1997-12-08 | 2004-03-17 | Bristol-Myers Squibb Company | Neue metformin salze und verfahren |
| US6099859A (en) | 1998-03-20 | 2000-08-08 | Andrx Pharmaceuticals, Inc. | Controlled release oral tablet having a unitary core |
| ES2224634T3 (es) * | 1998-04-29 | 2005-03-01 | Sumitomo Pharmaceuticals Company, Limited | Formulacion oral que comprende biguanida y un acido organico. |
| JP4606582B2 (ja) * | 1998-04-29 | 2011-01-05 | 大日本住友製薬株式会社 | ビグアナイド系薬物の内服製剤 |
| ATE306910T1 (de) * | 1998-07-30 | 2005-11-15 | Merck Sante Sas | Tablette mit verlängerter wirkstoffabgabe im magen |
| US6099862A (en) | 1998-08-31 | 2000-08-08 | Andrx Corporation | Oral dosage form for the controlled release of a biguanide and sulfonylurea |
| FR2796551B1 (fr) * | 1999-07-23 | 2003-07-25 | Lipha | Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant |
| FR2796940B1 (fr) * | 1999-07-26 | 2005-04-08 | Lipha | Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant |
| FR2809310B1 (fr) * | 2000-05-26 | 2004-02-13 | Centre Nat Rech Scient | Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant |
| AU2001213150A1 (en) * | 2000-08-03 | 2002-02-18 | Olga Evgenievna Kolesova | Composition of metformin with succinic acid or salts thereof and method for treating diabetes |
| US7959946B2 (en) | 2002-09-20 | 2011-06-14 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US7785627B2 (en) | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US8084058B2 (en) | 2002-09-20 | 2011-12-27 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US9060941B2 (en) | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| WO2007038979A1 (en) * | 2005-09-22 | 2007-04-12 | Swissco Development Ag | Effervescent metformin composition and tablets and granules made therefrom |
| JP4592818B2 (ja) * | 2007-01-29 | 2010-12-08 | ハナル バイオファーマ カンパニー リミテッド | N,n−ジメチルイミドジカルボンイミド酸ジアミドの酢酸塩、その製造方法、及びそれを含む薬剤学的組成物 |
| GR1007299B (el) * | 2010-03-24 | 2011-06-06 | Uni - Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Αβεε, | Πρωτοτυπη αναβραζουσα φαρμακευτικη συνθεση υδροχλωρικης μετφορμινης με τη μορφη δισκιου |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2448448A (en) * | 1942-06-08 | 1948-08-31 | Courtaulds Ltd | Dyeing of textile fibers containing nitrogen |
-
1987
- 1987-03-06 FR FR8703028A patent/FR2611500B1/fr not_active Expired - Lifetime
-
1988
- 1988-03-02 DE DE88400484T patent/DE3886075T2/de not_active Expired - Fee Related
- 1988-03-02 CA CA000560486A patent/CA1328606C/fr not_active Expired - Fee Related
- 1988-03-02 AT AT88400484T patent/ATE98120T1/de not_active IP Right Cessation
- 1988-03-02 EP EP88400484A patent/EP0283369B1/de not_active Expired - Lifetime
- 1988-03-03 IL IL85627A patent/IL85627A/xx not_active IP Right Cessation
- 1988-03-03 ZA ZA881540A patent/ZA881540B/xx unknown
- 1988-03-04 AU AU12727/88A patent/AU610134B2/en not_active Ceased
- 1988-03-04 DK DK116788A patent/DK169713B1/da not_active IP Right Cessation
- 1988-03-05 JP JP63050627A patent/JPH0818978B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0283369B1 (de) | 1993-12-08 |
| DE3886075T2 (de) | 1994-04-14 |
| DK169713B1 (da) | 1995-01-23 |
| JPH0818978B2 (ja) | 1996-02-28 |
| JPS63230628A (ja) | 1988-09-27 |
| ATE98120T1 (de) | 1993-12-15 |
| DK116788A (da) | 1988-09-07 |
| CA1328606C (fr) | 1994-04-19 |
| AU610134B2 (en) | 1991-05-16 |
| EP0283369A2 (de) | 1988-09-21 |
| AU1272788A (en) | 1988-09-08 |
| IL85627A0 (en) | 1988-08-31 |
| FR2611500A1 (fr) | 1988-09-09 |
| FR2611500B1 (fr) | 1990-05-04 |
| ZA881540B (en) | 1988-08-26 |
| DK116788D0 (da) | 1988-03-04 |
| EP0283369A3 (en) | 1989-11-29 |
| DE3886075D1 (de) | 1994-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| HP | Change in proprietorship | ||
| KB | Patent renewed | ||
| EXP | Patent expired |