ATE98120T1 - Verwendung von metformin zur herstellung von arzneimitteln. - Google Patents

Verwendung von metformin zur herstellung von arzneimitteln.

Info

Publication number: ATE98120T1
Authority: AT; Austria
Prior art keywords: metformin; pharmaceuticals; manufacture; preparation; medicaments
Prior art date: 1987-03-06

Application number

AT88400484T

Other languages

English (en)

Inventor

Nicolas Wiernsperger

Marcel Grand

Original Assignee

Lipha

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-03-06

Filing date

1988-03-02

Publication date

1993-12-15

1988-03-02 Application filed by Lipha filed Critical Lipha

1993-12-15 Application granted granted Critical

1993-12-15 Publication of ATE98120T1 publication Critical patent/ATE98120T1/de

Links

239000003814 drug Substances 0.000 title abstract 4
XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 title abstract 2
229960003105 metformin Drugs 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
206010029113 Neovascularisation Diseases 0.000 abstract 1
230000000496 anti-anoxic effect Effects 0.000 abstract 1
230000002253 anti-ischaemic effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT88400484T 1987-03-06 1988-03-02 Verwendung von metformin zur herstellung von arzneimitteln. ATE98120T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8703028A FR2611500B1 (fr)	1987-03-06	1987-03-06	Emploi de derives du biguanide dans la preparation de medicaments
EP88400484A EP0283369B1 (de)	1987-03-06	1988-03-02	Verwendung von Metformin zur Herstellung von Arzneimitteln

Publications (1)

Publication Number	Publication Date
ATE98120T1 true ATE98120T1 (de)	1993-12-15

Family

ID=9348653

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88400484T ATE98120T1 (de)	1987-03-06	1988-03-02	Verwendung von metformin zur herstellung von arzneimitteln.

Country Status (10)

Country	Link
EP (1)	EP0283369B1 (de)
JP (1)	JPH0818978B2 (de)
AT (1)	ATE98120T1 (de)
AU (1)	AU610134B2 (de)
CA (1)	CA1328606C (de)
DE (1)	DE3886075T2 (de)
DK (1)	DK169713B1 (de)
FR (1)	FR2611500B1 (de)
IL (1)	IL85627A (de)
ZA (1)	ZA881540B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5100919A (en) *	1984-03-19	1992-03-31	The Rockefeller University	Biguanides and derivatives thereof as inhibitors of advanced glycosylation of a target protein
AU651571B2 (en) *	1990-02-09	1994-07-28	Pharmacia & Upjohn Company	Use of insulin sensitizing agents to treat hypertension
US5356913A (en) *	1990-02-09	1994-10-18	The Upjohn Company	Use of insulin sensitizing agents to treat hypertension
DE4432757A1 (de) *	1994-09-14	1996-03-21	Boehringer Mannheim Gmbh	Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
WO1996008262A1 (en) *	1994-09-15	1996-03-21	Pharmagenesis, Inc.	Composition and method for immunotherapy
EP1039890B1 (de) *	1997-12-08	2004-03-17	Bristol-Myers Squibb Company	Neue metformin salze und verfahren
US6099859A (en)	1998-03-20	2000-08-08	Andrx Pharmaceuticals, Inc.	Controlled release oral tablet having a unitary core
ES2224634T3 (es) *	1998-04-29	2005-03-01	Sumitomo Pharmaceuticals Company, Limited	Formulacion oral que comprende biguanida y un acido organico.
JP4606582B2 (ja) *	1998-04-29	2011-01-05	大日本住友製薬株式会社	ビグアナイド系薬物の内服製剤
ATE306910T1 (de) *	1998-07-30	2005-11-15	Merck Sante Sas	Tablette mit verlängerter wirkstoffabgabe im magen
US6099862A (en)	1998-08-31	2000-08-08	Andrx Corporation	Oral dosage form for the controlled release of a biguanide and sulfonylurea
FR2796551B1 (fr) *	1999-07-23	2003-07-25	Lipha	Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant
FR2796940B1 (fr) *	1999-07-26	2005-04-08	Lipha	Nouveaux sels de metformine, leur procede d'obtention et les compositions pharmaceutiques en renfermant
FR2809310B1 (fr) *	2000-05-26	2004-02-13	Centre Nat Rech Scient	Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant
AU2001213150A1 (en) *	2000-08-03	2002-02-18	Olga Evgenievna Kolesova	Composition of metformin with succinic acid or salts thereof and method for treating diabetes
US7959946B2 (en)	2002-09-20	2011-06-14	Watson Pharmaceuticals, Inc.	Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7785627B2 (en)	2002-09-20	2010-08-31	Watson Pharmaceuticals, Inc.	Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8084058B2 (en)	2002-09-20	2011-12-27	Watson Pharmaceuticals, Inc.	Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en)	2002-09-20	2015-06-23	Actavis, Inc.	Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
WO2007038979A1 (en) *	2005-09-22	2007-04-12	Swissco Development Ag	Effervescent metformin composition and tablets and granules made therefrom
JP4592818B2 (ja) *	2007-01-29	2010-12-08	ハナルバイオファーマカンパニーリミテッド	Ｎ，ｎ−ジメチルイミドジカルボンイミド酸ジアミドの酢酸塩、その製造方法、及びそれを含む薬剤学的組成物
GR1007299B (el) *	2010-03-24	2011-06-06	Uni - Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Αβεε,	Πρωτοτυπη αναβραζουσα φαρμακευτικη συνθεση υδροχλωρικης μετφορμινης με τη μορφη δισκιου

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2448448A (en) *	1942-06-08	1948-08-31	Courtaulds Ltd	Dyeing of textile fibers containing nitrogen

1987
- 1987-03-06 FR FR8703028A patent/FR2611500B1/fr not_active Expired - Lifetime
1988
- 1988-03-02 DE DE88400484T patent/DE3886075T2/de not_active Expired - Fee Related
- 1988-03-02 CA CA000560486A patent/CA1328606C/fr not_active Expired - Fee Related
- 1988-03-02 AT AT88400484T patent/ATE98120T1/de not_active IP Right Cessation
- 1988-03-02 EP EP88400484A patent/EP0283369B1/de not_active Expired - Lifetime
- 1988-03-03 IL IL85627A patent/IL85627A/xx not_active IP Right Cessation
- 1988-03-03 ZA ZA881540A patent/ZA881540B/xx unknown
- 1988-03-04 AU AU12727/88A patent/AU610134B2/en not_active Ceased
- 1988-03-04 DK DK116788A patent/DK169713B1/da not_active IP Right Cessation
- 1988-03-05 JP JP63050627A patent/JPH0818978B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP0283369B1 (de)	1993-12-08
IL85627A (en)	1993-01-14
DE3886075T2 (de)	1994-04-14
DK169713B1 (da)	1995-01-23
JPH0818978B2 (ja)	1996-02-28
JPS63230628A (ja)	1988-09-27
DK116788A (da)	1988-09-07
CA1328606C (fr)	1994-04-19
AU610134B2 (en)	1991-05-16
EP0283369A2 (de)	1988-09-21
AU1272788A (en)	1988-09-08
IL85627A0 (en)	1988-08-31
FR2611500A1 (fr)	1988-09-09
FR2611500B1 (fr)	1990-05-04
ZA881540B (en)	1988-08-26
DK116788D0 (da)	1988-03-04
EP0283369A3 (en)	1989-11-29
DE3886075D1 (de)	1994-01-20

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Legal Events

Date	Code	Title
1994-08-15	UEP	Publication of translation of european patent specification
2001-12-15	EEIH	Change in the person of patent owner
2007-12-15	REN	Ceased due to non-payment of the annual fee