IL86115A - Chlorinating process for the preparation of 5-chloro-2-methoxynicotinic acid - Google Patents
Chlorinating process for the preparation of 5-chloro-2-methoxynicotinic acidInfo
- Publication number
- IL86115A IL86115A IL86115A IL8611588A IL86115A IL 86115 A IL86115 A IL 86115A IL 86115 A IL86115 A IL 86115A IL 8611588 A IL8611588 A IL 8611588A IL 86115 A IL86115 A IL 86115A
- Authority
- IL
- Israel
- Prior art keywords
- chloro
- methoxynicotinic acid
- preparation
- chlorinating
- chlorinating process
- Prior art date
Links
- DPIJNAABZCWXFD-UHFFFAOYSA-N 5-chloro-2-methoxypyridine-3-carboxylic acid Chemical compound COC1=NC=C(Cl)C=C1C(O)=O DPIJNAABZCWXFD-UHFFFAOYSA-N 0.000 title abstract 2
- FTEZJSXSARPZHJ-UHFFFAOYSA-N 2-methoxypyridine-3-carboxylic acid Chemical compound COC1=NC=CC=C1C(O)=O FTEZJSXSARPZHJ-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal hypochlorite Chemical class 0.000 abstract 1
- 239000003125 aqueous solvent Substances 0.000 abstract 1
- GHDLZGOOOLEJKI-UHFFFAOYSA-N benzenesulfonylurea Chemical class NC(=O)NS(=O)(=O)C1=CC=CC=C1 GHDLZGOOOLEJKI-UHFFFAOYSA-N 0.000 abstract 1
- 239000012320 chlorinating reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Inorganic materials Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 abstract 1
- 239000003538 oral antidiabetic agent Substances 0.000 abstract 1
- 229940127209 oral hypoglycaemic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B39/00—Halogenation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/043,056 US4716231A (en) | 1987-04-27 | 1987-04-27 | Chlorination of 2-methoxynicotinic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL86115A0 IL86115A0 (en) | 1988-11-15 |
| IL86115A true IL86115A (en) | 1992-02-16 |
Family
ID=21925225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL86115A IL86115A (en) | 1987-04-27 | 1988-04-19 | Chlorinating process for the preparation of 5-chloro-2-methoxynicotinic acid |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4716231A (fr) |
| EP (1) | EP0289180B1 (fr) |
| JP (1) | JPH0625117B2 (fr) |
| KR (1) | KR900006208B1 (fr) |
| AT (1) | ATE82965T1 (fr) |
| AU (1) | AU581829B2 (fr) |
| CA (1) | CA1297114C (fr) |
| DE (1) | DE3876277T2 (fr) |
| DK (1) | DK168624B1 (fr) |
| ES (1) | ES2035917T3 (fr) |
| FI (1) | FI89044C (fr) |
| GR (1) | GR3006528T3 (fr) |
| HU (1) | HU202206B (fr) |
| IE (1) | IE61278B1 (fr) |
| IL (1) | IL86115A (fr) |
| NZ (1) | NZ224376A (fr) |
| PT (1) | PT87334B (fr) |
| ZA (1) | ZA882937B (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6133447A (en) * | 1998-02-27 | 2000-10-17 | Novartis Crop Protection, Inc. | Process for the preparation of substituted pyridines |
| JP5148836B2 (ja) * | 2005-04-21 | 2013-02-20 | 石原産業株式会社 | ニコチン酸誘導体又はその塩の製造方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1832484A (en) * | 1928-10-11 | 1931-11-17 | Dow Chemical Co | Derivatives of para-hydroxy-diphenyl |
| US2365981A (en) * | 1941-12-20 | 1944-12-26 | Commercial Solvents Corp | Production of chlorinated nitro hydrocarbons |
| US3879403A (en) * | 1973-05-04 | 1975-04-22 | Pfizer | Benzenesulfonylurea derivatives |
-
1987
- 1987-04-27 US US07/043,056 patent/US4716231A/en not_active Expired - Fee Related
-
1988
- 1988-04-18 EP EP88303449A patent/EP0289180B1/fr not_active Expired - Lifetime
- 1988-04-18 AT AT88303449T patent/ATE82965T1/de not_active IP Right Cessation
- 1988-04-18 ES ES198888303449T patent/ES2035917T3/es not_active Expired - Lifetime
- 1988-04-18 DE DE8888303449T patent/DE3876277T2/de not_active Expired - Fee Related
- 1988-04-19 IL IL86115A patent/IL86115A/xx not_active IP Right Cessation
- 1988-04-25 JP JP63102352A patent/JPH0625117B2/ja not_active Expired - Lifetime
- 1988-04-25 KR KR1019880004705A patent/KR900006208B1/ko not_active Expired
- 1988-04-25 CA CA000564980A patent/CA1297114C/fr not_active Expired - Lifetime
- 1988-04-26 NZ NZ224376A patent/NZ224376A/xx unknown
- 1988-04-26 AU AU15144/88A patent/AU581829B2/en not_active Ceased
- 1988-04-26 HU HU882104A patent/HU202206B/hu not_active IP Right Cessation
- 1988-04-26 PT PT87334A patent/PT87334B/pt not_active IP Right Cessation
- 1988-04-26 FI FI881949A patent/FI89044C/fi not_active IP Right Cessation
- 1988-04-26 ZA ZA882937A patent/ZA882937B/xx unknown
- 1988-04-26 DK DK225888A patent/DK168624B1/da not_active IP Right Cessation
- 1988-04-26 IE IE124688A patent/IE61278B1/en not_active IP Right Cessation
-
1992
- 1992-12-14 GR GR920402902T patent/GR3006528T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0289180A2 (fr) | 1988-11-02 |
| FI881949L (fi) | 1988-10-28 |
| AU1514488A (en) | 1988-10-27 |
| EP0289180A3 (en) | 1989-12-13 |
| DE3876277T2 (de) | 1993-04-01 |
| DK225888A (da) | 1988-10-28 |
| CA1297114C (fr) | 1992-03-10 |
| KR880012505A (ko) | 1988-11-28 |
| JPH0625117B2 (ja) | 1994-04-06 |
| FI881949A0 (fi) | 1988-04-26 |
| IE61278B1 (en) | 1994-10-19 |
| US4716231A (en) | 1987-12-29 |
| ZA882937B (en) | 1989-12-27 |
| ATE82965T1 (de) | 1992-12-15 |
| JPS63280065A (ja) | 1988-11-17 |
| GR3006528T3 (fr) | 1993-06-30 |
| ES2035917T3 (es) | 1993-05-01 |
| IE881246L (en) | 1988-10-27 |
| HU202206B (en) | 1991-02-28 |
| HUT49331A (en) | 1989-09-28 |
| AU581829B2 (en) | 1989-03-02 |
| PT87334A (pt) | 1988-05-01 |
| PT87334B (pt) | 1992-08-31 |
| IL86115A0 (en) | 1988-11-15 |
| FI89044C (fi) | 1993-08-10 |
| FI89044B (fi) | 1993-04-30 |
| DE3876277D1 (de) | 1993-01-14 |
| EP0289180B1 (fr) | 1992-12-02 |
| DK168624B1 (da) | 1994-05-09 |
| KR900006208B1 (ko) | 1990-08-25 |
| NZ224376A (en) | 1989-12-21 |
| DK225888D0 (da) | 1988-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |