IL88086A - Azetidinyl quinolone carboxylic acids esters and amides antibacterial compositions containing said compounds and uses thereof - Google Patents

Azetidinyl quinolone carboxylic acids esters and amides antibacterial compositions containing said compounds and uses thereof

Info

Publication number: IL88086A
Authority: IL; Israel
Prior art keywords: alkyl; azetidinyl; amino; amides; compounds
Prior art date: 1987-10-26

Application number

IL8808688A

Other languages

English (en)

Other versions

IL88086A0 (en

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-26

Filing date

1988-10-19

Publication date

1997-01-10

1988-10-19 Application filed by Pfizer filed Critical Pfizer

1989-06-30 Publication of IL88086A0 publication Critical patent/IL88086A0/xx

1997-01-10 Publication of IL88086A publication Critical patent/IL88086A/xx

Links

IYWFIOQXOILMIG-UHFFFAOYSA-N C12=CC=CC=C2NC(=O)C(C(=O)O)=C1N1CCC1 Chemical class C12=CC=CC=C2NC(=O)C(C(=O)O)=C1N1CCC1 IYWFIOQXOILMIG-UHFFFAOYSA-N 0.000 title 1
150000001408 amides Chemical class 0.000 title 1
230000000844 anti-bacterial effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
239000000203 mixture Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 9
-1 1-azetidinyl Chemical group 0.000 abstract 5
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000001475 halogen functional group Chemical group 0.000 abstract 3
150000003839 salts Chemical class 0.000 abstract 3
YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 abstract 1
239000003513 alkali Substances 0.000 abstract 1
125000005236 alkanoylamino group Chemical group 0.000 abstract 1
125000004103 aminoalkyl group Chemical group 0.000 abstract 1
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)
Steroid Compounds (AREA)

IL8808688A 1987-10-26 1988-10-19 Azetidinyl quinolone carboxylic acids esters and amides antibacterial compositions containing said compounds and uses thereof IL88086A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US1987/002792 WO1989003828A1 (en)	1987-10-26	1987-10-26	Azetidinyl quinolone carboxylic acids and esters

Publications (2)

Publication Number	Publication Date
IL88086A0 IL88086A0 (en)	1989-06-30
IL88086A true IL88086A (en)	1997-01-10

Family

ID=22202632

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL8808688A IL88086A (en)	1987-10-26	1988-10-19	Azetidinyl quinolone carboxylic acids esters and amides antibacterial compositions containing said compounds and uses thereof

Country Status (19)

Country	Link
US (1)	US5039683A (de)
EP (1)	EP0314362B1 (de)
JP (1)	JPH01146879A (de)
KR (1)	KR900006741B1 (de)
AT (1)	ATE100805T1 (de)
AU (1)	AU602431B2 (de)
DE (1)	DE3887443T2 (de)
DK (1)	DK591588A (de)
ES (1)	ES2061680T3 (de)
FI (1)	FI893048A7 (de)
HU (1)	HU205105B (de)
IE (1)	IE63284B1 (de)
IL (1)	IL88086A (de)
MY (1)	MY103436A (de)
NO (1)	NO892616L (de)
NZ (1)	NZ226689A (de)
PT (1)	PT88837B (de)
WO (1)	WO1989003828A1 (de)
ZA (1)	ZA887927B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2634483B2 (fr) *	1987-12-29	1994-03-04	Esteve Labor Dr	Derives des acides 7-(1-azetidinyl)-1,4-dihydro-4-oxoquinoleine-3-carboxyliques, leur preparation et leur application en tant que medicaments
US5173484A (en) *	1988-02-05	1992-12-22	Bayer Aktiengesellschaft	Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
EP0366189A3 (de) *	1988-10-24	1992-01-02	Norwich Eaton Pharmaceuticals, Inc.	Antimikrobielle Lactam-Quinolone
FR2649106A2 (fr) *	1989-06-29	1991-01-04	Esteve Labor Dr	Derives d'acides pyridone carboxyliques azetidinyl substitues, leur preparation et leur application en tant que medicament
FR2644455B1 (fr) *	1989-03-16	1994-09-23	Esteve Labor Dr	Derives d'acides pyridone carboxyliques azetidinyl substitues, leur preparation et leur application en tant que medicaments
FR2654728B2 (fr) *	1989-03-16	1994-09-23	Esteve Labor Dr	Derives d'acides pyridone carboxyliques azetidinyl substitues, leur preparation et leur application en tant que medicament.
NO177302C (no) *	1989-03-16	1995-08-23	Esteve Labor Dr	Analogifremgangsmåte til fremstilling av terapeutisk aktive substituerte azetidinylkinolon(naftyridon)karboksylsyrederivater
FR2690161B1 (fr) *	1992-04-16	1995-06-30	Esteve Labor Dr	Derives de pyridone azetidinyl substitues avec activite antimicrobienne.
US5885983A (en) *	1996-05-10	1999-03-23	Bristol-Myers Squibb Company	Inhibitors of microsomal triglyceride transfer protein and method
WO2005019224A2 (en) *	2003-06-06	2005-03-03	Cadila Healthcare Limited	Novel antiinfective compounds
WO2005026146A1 (en) *	2003-09-12	2005-03-24	Warner-Lambert Company Llc	Azetidinyl quinolones as antibacterial agents

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4670444B1 (en) *	1980-09-03	1999-02-09	Bayer Ag	and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
IE55898B1 (en) *	1982-09-09	1991-02-14	Warner Lambert Co	Antibacterial agents
US4665079A (en) *	1984-02-17	1987-05-12	Warner-Lambert Company	Antibacterial agents
NZ208470A (en) *	1983-07-18	1988-06-30	Abbott Lab	6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic acid derivatives and antibacterial compositions containing such
JPS6089480A (ja) *	1983-10-21	1985-05-20	Dainippon Pharmaceut Co Ltd	ピリドンカルボン酸誘導体
JPS60126284A (ja) *	1983-12-09	1985-07-05	Dainippon Pharmaceut Co Ltd	ピリドンカルボン酸誘導体およびその塩
US4623650A (en) *	1984-12-06	1986-11-18	Pfizer Inc.	Antibiotic derivatives of 7-phenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids
JPS61137885A (ja) *	1984-12-08	1986-06-25	Dainippon Pharmaceut Co Ltd	１，８−ナフチリジン誘導体、そのエステルおよびその塩
JPS61152682A (ja) *	1984-12-27	1986-07-11	Dainippon Pharmaceut Co Ltd	ピリドンカルボン酸誘導体、そのエステルおよびその塩
JPS61282382A (ja) *	1985-06-06	1986-12-12	Dainippon Pharmaceut Co Ltd	フエニル置換１，８−ナフチリジン誘導体、そのエステルおよびその塩
JPS62469A (ja) *	1985-06-27	1987-01-06	Dainippon Pharmaceut Co Ltd	新規キノロン誘導体、そのエステルおよびその塩
JPS6219883A (ja) *	1985-07-19	1987-01-28	Ricoh Co Ltd	色替え可能な現像装置
JPH0674260B2 (ja) *	1985-08-01	1994-09-21	大日本製薬株式会社	キノリン誘導体、そのエステルおよびその塩
JPS62215572A (ja) *	1986-03-17	1987-09-22	Kyorin Pharmaceut Co Ltd	キノロンカルボン酸誘導体
FI871419L (fi) *	1986-03-31	1987-10-01	Sankyo Co	Kinolin-3-karboxylsyraderivat, deras framstaellning och anvaendning.
JPH0689480A (ja) *	1992-09-09	1994-03-29	Ricoh Co Ltd	光磁気記録再生装置

1987
- 1987-10-26 US US07/365,156 patent/US5039683A/en not_active Expired - Lifetime
- 1987-10-26 HU HU876039A patent/HU205105B/hu not_active IP Right Cessation
- 1987-10-26 WO PCT/US1987/002792 patent/WO1989003828A1/en not_active Ceased
1988
- 1988-10-17 AT AT88309722T patent/ATE100805T1/de not_active IP Right Cessation
- 1988-10-17 DE DE88309722T patent/DE3887443T2/de not_active Expired - Fee Related
- 1988-10-17 EP EP88309722A patent/EP0314362B1/de not_active Expired - Lifetime
- 1988-10-17 ES ES88309722T patent/ES2061680T3/es not_active Expired - Lifetime
- 1988-10-19 IL IL8808688A patent/IL88086A/xx not_active IP Right Cessation
- 1988-10-21 MY MYPI88001199A patent/MY103436A/en unknown
- 1988-10-24 PT PT88837A patent/PT88837B/pt not_active IP Right Cessation
- 1988-10-24 JP JP63267982A patent/JPH01146879A/ja active Pending
- 1988-10-24 ZA ZA887927A patent/ZA887927B/xx unknown
- 1988-10-25 IE IE321788A patent/IE63284B1/en not_active IP Right Cessation
- 1988-10-25 DK DK591588A patent/DK591588A/da not_active Application Discontinuation
- 1988-10-25 KR KR1019880013896A patent/KR900006741B1/ko not_active Expired
- 1988-10-25 AU AU24325/88A patent/AU602431B2/en not_active Ceased
- 1988-10-25 NZ NZ226689A patent/NZ226689A/xx unknown
1989
- 1989-06-21 FI FI893048A patent/FI893048A7/fi not_active Application Discontinuation
- 1989-06-23 NO NO89892616A patent/NO892616L/no unknown

Also Published As

Publication number	Publication date
ES2061680T3 (es)	1994-12-16
DK591588A (da)	1989-04-27
IE883217L (en)	1989-04-26
KR900006741B1 (ko)	1990-09-20
US5039683A (en)	1991-08-13
DE3887443T2 (de)	1994-05-11
JPH01146879A (ja)	1989-06-08
IE63284B1 (en)	1995-04-05
EP0314362A2 (de)	1989-05-03
HU205105B (en)	1992-03-30
FI893048A0 (fi)	1989-06-21
NO892616D0 (no)	1989-06-23
DK591588D0 (da)	1988-10-25
FI893048A7 (fi)	1989-06-21
ZA887927B (en)	1990-06-27
AU602431B2 (en)	1990-10-11
KR890006616A (ko)	1989-06-14
AU2432588A (en)	1988-10-25
PT88837B (pt)	1993-01-29
NO892616L (no)	1989-06-23
NZ226689A (en)	1990-03-27
DE3887443D1 (de)	1994-03-10
WO1989003828A1 (en)	1989-05-05
EP0314362A3 (en)	1989-10-18
IL88086A0 (en)	1989-06-30
HUT52497A (en)	1990-07-28
ATE100805T1 (de)	1994-02-15
MY103436A (en)	1993-06-30
EP0314362B1 (de)	1994-01-26

Similar Documents

Publication	Publication Date	Title
IL88086A (en)	1997-01-10	Azetidinyl quinolone carboxylic acids esters and amides antibacterial compositions containing said compounds and uses thereof
ES8602755A1 (es)	1985-12-01	Un procedimiento para la obtencion de agentes antibacteria- nos a base de acidos 7-amino-1-ciclopropil-6,8-difluor-1, 4-dihidro-4-oxo-3-quinolincarboxilicos
DE3685248D1 (de)	1992-06-17	7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel.
AU3292195A (en)	1996-04-18	New imidazolidines substituted by a heterocycle, their preparation process and intermediates, their use as medicaments and the pharmaceutical compositions containing them
ES8801833A1 (es)	1988-02-16	Un procedimiento para la preparacion de un compuesto.
GB1336802A (en)	1973-11-14	Cephalosporin complexes and process for producing cephalosporin antibiotics therefrom
FR2346014A1 (fr)	1977-10-28	Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2258840A1 (en)	1975-08-22	(4-Phenylpiperazino) alkyl esters - with analgesic activity for human and veterinary use
IL119054A0 (en)	1996-11-14	Substituted 4H-pyrans their preparation and pharmaceutical compositions containing them
FR2244514A1 (en)	1975-04-18	1,2-Dihydroquinoline derivs - useful as anti-inflammatories
ES457473A1 (es)	1978-07-01	Un procedimiento para preparar derivados de cefalosporina.
FR2361893A2 (fr)	1978-03-17	Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
IT1048274B (it)	1980-11-20	Esteri di penicilline e di cefauosporine
FR2193822A1 (en)	1974-02-22	Trifluoromethoxy quinoline derivs - useful as inters in org. syntheses
HUT48893A (en)	1989-07-28	Process for producing new cepheme derivatives
FR2228779A1 (en)	1975-08-22	(4-Phenylpiperazino) alkyl esters - with analgesic activity for human and veterinary use
FR2361894A2 (fr)	1978-03-17	Nouvelles oximes derivees de l'acide 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2007386A1 (en)	1970-01-09	Phenylhydrazones antibacterial
FR2007387A1 (en)	1970-01-09	P-hydroxyphenylhydrazones antibacterial
FR2285889A1 (fr)	1976-04-23	Nouveaux derives de la cephalosporine, leur preparation et les compositions qui les contiennent
FR2388814A1 (fr)	1978-11-24	Nouveaux derives de l'acide clavulanique, utilisables comme medicament
FR2271822A2 (en)	1975-12-19	Acyl derivs of antibiotic WS-4545 - active on oral administration against gram negative bacteria
ES2005749A6 (es)	1989-03-16	Procedimiento para preparar un compuesto de cefem.
ES8404362A1 (es)	1984-04-16	Un procedimiento para preparar nuevos compuestos de cefem.
IT1156890B (it)	1987-02-04	Agente battericida e procedimento per la sua preparazione

Legal Events

Date	Code	Title
1997-07-13	FF	Patent granted
1997-11-20	KB	Patent renewed
1999-10-28	RH	Patent void