IL90815A - Compositions comprising quinoline derivatives, sume such novel compounds and processes for the preparation of such derivatives - Google Patents

Compositions comprising quinoline derivatives, sume such novel compounds and processes for the preparation of such derivatives

Info

Publication number: IL90815A
Authority: IL; Israel
Prior art keywords: derivatives; sume; compositions; processes; preparation
Prior art date: 1988-07-12

Application number

IL90815A

Other languages

English (en)

Other versions

IL90815A0 (en

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-07-12

Filing date

1989-06-30

Publication date

1993-07-08

1989-06-30 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1990-01-18 Publication of IL90815A0 publication Critical patent/IL90815A0/xx

1993-07-08 Publication of IL90815A publication Critical patent/IL90815A/xx

Links

229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title abstract 2
125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 title 1
239000000203 mixture Substances 0.000 title 1
102000001494 Sterol O-Acyltransferase Human genes 0.000 abstract 1
108010054082 Sterol O-acyltransferase Proteins 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
- C07D215/60—N-oxides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Quinoline Compounds (AREA)

IL90815A 1988-07-12 1989-06-30 Compositions comprising quinoline derivatives, sume such novel compounds and processes for the preparation of such derivatives IL90815A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP17413788		1988-07-12
JP21426688		1988-08-29
JP7592589		1989-03-27

Publications (2)

Publication Number	Publication Date
IL90815A0 IL90815A0 (en)	1990-01-18
IL90815A true IL90815A (en)	1993-07-08

Family

ID=27301993

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL90815A IL90815A (en)	1988-07-12	1989-06-30	Compositions comprising quinoline derivatives, sume such novel compounds and processes for the preparation of such derivatives

Country Status (17)

Country	Link
US (1)	US5254565A (fr)
EP (1)	EP0354994B1 (fr)
KR (1)	KR900001656A (fr)
AT (1)	ATE117681T1 (fr)
AU (1)	AU616542B2 (fr)
CA (1)	CA1333068C (fr)
DE (1)	DE68920796T2 (fr)
DK (1)	DK345989A (fr)
ES (1)	ES2066808T3 (fr)
FI (1)	FI93353C (fr)
GR (1)	GR3015554T3 (fr)
HU (1)	HU210861B (fr)
IE (1)	IE892088L (fr)
IL (1)	IL90815A (fr)
NO (1)	NO177300C (fr)
NZ (1)	NZ229911A (fr)
PT (1)	PT91121B (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW205037B (fr) *	1989-10-06	1993-05-01	Takeda Pharm Industry Co Ltd
JPH03181465A (ja) *	1989-12-11	1991-08-07	Takeda Chem Ind Ltd	キノリン誘導体
DE4014171A1 (de) *	1990-05-03	1991-11-07	Basf Ag	Cyanochinolinverbindungen
US5143919A (en) *	1990-08-17	1992-09-01	Takeda Chemical Industries, Ltd.	Thienopyridine derivatives and their pharmaceutical use
US5256782A (en) *	1990-08-17	1993-10-26	Takeda Chemical Industries, Ltd.	Thienopyridine derivatives which are intermediates
US5668136A (en) *	1990-09-25	1997-09-16	Eisai Co., Ltd.	Trisubstituted benzene derivatives, composition and methods of treatment
JPH059179A (ja) *	1990-09-27	1993-01-19	Takeda Chem Ind Ltd	複素環化合物、その製造法及びａｃａｔ阻害剤
AU1879792A (en) *	1991-04-26	1992-12-21	Pfizer Inc.	4-aryl-3-(heteroarylureido)quinoline derivatives
IL101785A0 (en) *	1991-05-10	1992-12-30	Fujisawa Pharmaceutical Co	Urea derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
ES2125325T3 (es) *	1992-01-23	1999-03-01	Pfizer	Derivados de 4-fenil-3-(heteroarilureido)-1,2-dihidro-2-oxoquinolina como agentes antihipercolesterolemicos y antiateroscleroticos.
TW232013B (fr) *	1992-04-24	1994-10-11	Takeda Pharm Industry Co Ltd
US5364875A (en) *	1992-05-11	1994-11-15	The Du Pont Merck Pharmaceutical Company	Imidazoles linked to bicyclic heterocyclic groups for the treatment of atherosclerosis
US5310748A (en) *	1992-05-11	1994-05-10	The Du Pont Merck Pharmaceutical Company	Imidazoles for the treatment of atherosclerosis
ATE159715T1 (de) *	1992-07-20	1997-11-15	Eisai Co Ltd	Benzolderivate
EP0585913B1 (fr) *	1992-09-04	1997-12-29	Takeda Chemical Industries, Ltd.	Composés hétérocycliques condensés, leur production et usage
US5565472A (en) *	1992-12-21	1996-10-15	Pfizer Inc.	4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
GB9302275D0 (en) *	1993-02-05	1993-03-24	Smithkline Beecham Plc	Novel compounds
NZ264063A (en) *	1993-08-13	1995-11-27	Nihon Nohyaku Co Ltd	N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
US5596001A (en) *	1993-10-25	1997-01-21	Pfizer Inc.	4-aryl-3-(heteroarylureido)quinoline derivatves
TW263498B (fr) *	1993-11-10	1995-11-21	Takeda Pharm Industry Co Ltd
US5491152A (en) *	1994-03-23	1996-02-13	The Du Pont Merck Pharmaceutical Company	Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis
JP3720395B2 (ja) *	1994-09-20	2005-11-24	京都薬品工業株式会社	新規ヘテロ環誘導体、その製造方法およびその医薬用途
DE69633059T2 (de) *	1995-05-31	2005-08-18	Sumitomo Pharmaceuticals Co., Ltd.	Neue naphthyridinderivate.
DK0866059T3 (da)	1995-10-05	2002-03-25	Kyoto Pharma Ind	Nye heterocykliske derivater og medicinsk anvendelse deraf
CA2190708A1 (fr) *	1995-12-08	1997-06-09	Johannes Aebi	Derives de substitution aminoalkyles de composes benzo-heterocycliques
DE19627430A1 (de) *	1996-07-08	1998-01-15	Bayer Ag	Bicyclisch kondensierte Pyridine
BR0312734A (pt) *	2002-07-17	2005-04-26	Kyoto Pharma Ind	Composto de indolina e uso medicinal do mesmo
EP1868998B1 (fr) *	2005-04-01	2016-05-25	VFP Therapies	Nouveaux composés hétérocycliques, leur préparation et leur utilisation come médicament en particulier come agents anti-alzheimer
US20160332971A1 (en) *	2015-05-15	2016-11-17	University Of Kentucky Research Foundation	Arylquinoline, arylquinolone and arylthioquinolone derivatives and use thereof to treat cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO133758C (fr) *	1970-04-04	1976-06-23	Takeda Chemical Industries Ltd
US3819634A (en) *	1970-07-23	1974-06-25	Takeda Chemical Industries Ltd	4-phenyl-3-thioacrylaminoquinolines
JPS555502B1 (fr) *	1971-07-31	1980-02-07

1989
- 1989-06-27 IE IE892088A patent/IE892088L/xx unknown
- 1989-06-30 IL IL90815A patent/IL90815A/xx not_active IP Right Cessation
- 1989-07-10 NO NO892851A patent/NO177300C/no unknown
- 1989-07-11 EP EP89112683A patent/EP0354994B1/fr not_active Expired - Lifetime
- 1989-07-11 NZ NZ229911A patent/NZ229911A/en unknown
- 1989-07-11 AU AU38025/89A patent/AU616542B2/en not_active Ceased
- 1989-07-11 HU HU893485A patent/HU210861B/hu not_active IP Right Cessation
- 1989-07-11 FI FI893361A patent/FI93353C/fi not_active IP Right Cessation
- 1989-07-11 PT PT91121A patent/PT91121B/pt not_active IP Right Cessation
- 1989-07-11 AT AT89112683T patent/ATE117681T1/de active
- 1989-07-11 DE DE68920796T patent/DE68920796T2/de not_active Expired - Fee Related
- 1989-07-11 ES ES89112683T patent/ES2066808T3/es not_active Expired - Lifetime
- 1989-07-11 CA CA000605291A patent/CA1333068C/fr not_active Expired - Fee Related
- 1989-07-12 DK DK345989A patent/DK345989A/da not_active Application Discontinuation
- 1989-07-12 KR KR1019890009937A patent/KR900001656A/ko not_active Abandoned
1991
- 1991-12-16 US US07/807,813 patent/US5254565A/en not_active Expired - Fee Related
1995
- 1995-03-28 GR GR950400730T patent/GR3015554T3/el unknown

Also Published As

Publication number	Publication date
NO177300C (no)	1995-08-23
NO892851L (no)	1990-01-15
PT91121B (pt)	1995-01-31
NO892851D0 (no)	1989-07-10
FI93353C (fi)	1995-03-27
NO177300B (no)	1995-05-15
US5254565A (en)	1993-10-19
ATE117681T1 (de)	1995-02-15
AU616542B2 (en)	1991-10-31
PT91121A (pt)	1990-02-08
DE68920796T2 (de)	1995-07-06
ES2066808T3 (es)	1995-03-16
HU210861B (en)	1995-08-28
GR3015554T3 (en)	1995-06-30
KR900001656A (ko)	1990-02-27
DK345989D0 (da)	1989-07-12
EP0354994A2 (fr)	1990-02-21
FI893361A0 (fi)	1989-07-11
DE68920796D1 (de)	1995-03-09
IE892088L (en)	1990-01-12
AU3802589A (en)	1990-01-18
NZ229911A (en)	1991-08-27
EP0354994A3 (fr)	1991-05-15
IL90815A0 (en)	1990-01-18
DK345989A (da)	1990-01-13
FI893361L (fi)	1990-01-13
CA1333068C (fr)	1994-11-15
FI93353B (fi)	1994-12-15
EP0354994B1 (fr)	1995-01-25
HUT52059A (en)	1990-06-28

Legal Events

Date	Code	Title	Description
2000-06-29	RH	Patent void

Publication	Publication Date	Title
IL90815A (en)	1993-07-08	Compositions comprising quinoline derivatives, sume such novel compounds and processes for the preparation of such derivatives
EP0256503A3 (en)	1989-07-19	Pyridinecarboxamide derivatives and their use as fungicide
TW368501B (en)	1999-09-01	7-(2-aminoethyl)-benzothiazolones
HU906360D0 (en)	1991-04-29	Process for producing quinoline derivatives and pharmaceutical preparatives containing such compounds
AU657106B2 (en)	1995-03-02	Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents
DK0474243T3 (da)	1998-12-07	1-methylcarbapenemderivater og fremgangsmåde til fremstilling deraf
PL309874A1 (en)	1996-02-05	Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives
AU591640B2 (en)	1989-12-14	Quinolonecarboxylic acid derivatives
PH25181A (en)	1991-03-27	New alkane sulfoanilide derivatives and pharmaceutical composition comprising the same
ATE71621T1 (de)	1992-02-15	Substituierte azolylethanolderivate als pflanzenwachstumsregulatoren.
ES8801545A1 (es)	1988-02-01	Un procedimiento para la preparacion de compuestos aminoheterociclicos
NZ189091A (en)	1981-07-13	Prostaglandin derivatives
ES475004A1 (es)	1979-11-01	Un procedimiento para la preparacion de sales de eteres del acido clavulanico
ES2044883T3 (es)	1994-01-16	Procedimiento para preparar quinoxalinas sustituidas.