IL91415A - Anti-viral compositions comprising compounds of adenosine or salts or a metabolite thereof - Google Patents

Anti-viral compositions comprising compounds of adenosine or salts or a metabolite thereof

Info

Publication number
IL91415A
IL91415A IL9141589A IL9141589A IL91415A IL 91415 A IL91415 A IL 91415A IL 9141589 A IL9141589 A IL 9141589A IL 9141589 A IL9141589 A IL 9141589A IL 91415 A IL91415 A IL 91415A
Authority
IL
Israel
Prior art keywords
ipa
virus
composition
cells
hiv
Prior art date
Application number
IL9141589A
Other languages
English (en)
Other versions
IL91415A0 (en
Original Assignee
Prendergast Patrick T
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prendergast Patrick T filed Critical Prendergast Patrick T
Publication of IL91415A0 publication Critical patent/IL91415A0/xx
Publication of IL91415A publication Critical patent/IL91415A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL9141589A 1988-08-25 1989-08-24 Anti-viral compositions comprising compounds of adenosine or salts or a metabolite thereof IL91415A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE882585A IE882585L (en) 1988-08-25 1988-08-25 Viral treatment system

Publications (2)

Publication Number Publication Date
IL91415A0 IL91415A0 (en) 1990-04-29
IL91415A true IL91415A (en) 1995-08-31

Family

ID=11035556

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9141589A IL91415A (en) 1988-08-25 1989-08-24 Anti-viral compositions comprising compounds of adenosine or salts or a metabolite thereof

Country Status (12)

Country Link
US (1) US5681831A (de)
EP (1) EP0355825A3 (de)
JP (1) JP3237836B2 (de)
KR (1) KR900002786A (de)
AU (1) AU636574B2 (de)
CA (1) CA1339854C (de)
DK (1) DK418489A (de)
FI (1) FI893948A7 (de)
IE (1) IE882585L (de)
IL (1) IL91415A (de)
OA (1) OA09427A (de)
ZA (1) ZA896450B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3725554A1 (de) * 1987-08-01 1989-02-09 Hoechst Ag Pharmazeutisches kombinationspraeparat sowie dessen herstellung und verwendung
AU7920491A (en) * 1990-06-21 1992-01-02 Patrick T. Prendergast Administering particular compounds against various parasites, mycoplasmas, other indications and other infections
EP0901375A1 (de) * 1996-04-17 1999-03-17 Patrick Thomas Prendergast Dhea-kombinationstherapie
US5789416B1 (en) * 1996-08-27 1999-10-05 Cv Therapeutics Inc N6 mono heterocyclic substituted adenosine derivatives
FR2759091B1 (fr) * 1997-02-06 1999-03-19 Expertises Ind Et Procede biologique d'obtention de nouveaux derives de l'adenosine et les compositions pharmaceutiques qui les contiennent
WO1998047516A1 (en) * 1997-04-17 1998-10-29 Prendergast Patrick T Combination therapy utilising 17-ketosteroids and interleukin inhibitors, or interleukin-10 potionally with interleukin inhibitors
US6800616B2 (en) 1998-02-26 2004-10-05 Supergen, Inc. Treatment of HIV infections
CA2552596A1 (en) * 2005-08-09 2007-02-09 Solvay Pharmaceuticals B.V. Methods and systems for determining mid-value titers
AU2011230619C1 (en) 2010-03-25 2016-06-23 Oregon Health & Science University CMV glycoproteins and recombinant vectors
HUE037408T2 (hu) 2011-06-10 2018-08-28 Univ Oregon Health & Science CMV glikoproteinek és rekombináns vektorok
CA2789539A1 (en) 2011-09-12 2013-03-12 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
EP2848937A1 (de) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Verfahren zur Identifizierung neuartiger HIV-1-Immunogene
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3069730A3 (de) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759011A (fr) * 1969-11-17 1971-05-17 Wellcome Found Aminopurines
DE2052596A1 (de) * 1970-10-27 1972-05-04 Boehringer Mannheim Gmbh, 6800 Mannheim Neuartige Verwendung von N(6)-substituierten Adenosin-Derivaten
US3758684A (en) * 1971-09-07 1973-09-11 Burroughs Wellcome Co Treating dna virus infections with amino purine derivatives
US3966916A (en) * 1972-09-09 1976-06-29 Boehringer Mannheim G.M.B.H. N(6)-disubstituted adenoisine compounds and therapeutic compositions
US4016262A (en) * 1973-08-01 1977-04-05 Boehringer Mannheim G.M.B.H. Therapeutic compositions and methods employing N(6)-disubstituted adenosine compounds
US4007186A (en) * 1974-09-20 1977-02-08 Emanuel Carl F Process for preparing uric acid
JPS5712999A (en) * 1980-06-25 1982-01-22 Chiyokichi Iizuka Antibiral agent and its preparation
JPS57171998A (en) * 1981-04-15 1982-10-22 Fujisawa Pharmaceut Co Ltd Adenosine derivative and its salt, preparation thereof and medicinal composition containing the same
US4558051A (en) * 1983-10-11 1985-12-10 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US5093318A (en) * 1983-11-01 1992-03-03 Scripps Clinic And Research Foundation Immunostimulating guanosine derivatives and their pharmaceutical compositions
US4687733A (en) * 1984-01-30 1987-08-18 Ohio State University Early cancer detection method
US4657897A (en) * 1984-06-22 1987-04-14 Warner-Lambert Company N6 -substituted adenosines for treating pain
US4791103A (en) * 1985-02-08 1988-12-13 Warner-Lambert Company 2,N6 -disubstituted adenosines, derivatives and methods of use
US4605644A (en) * 1985-02-07 1986-08-12 Regents Of The University Of Minnesota Method for stimulating recovery from ischemia employing ribose and adenine
JP2930589B2 (ja) * 1986-10-06 1999-08-03 ザ ユニバーシィティ オブ バージニア アルミニ パテンツ ファンデーション 外科手術中における改善された心臓保護のためのアデノシン，ヒポキサンチン及びリボース含有溶液の使用
US4843066A (en) * 1986-11-27 1989-06-27 Nippon Zoki Pharmaceutical Co., Ltd. Novel adenosine derivatives and pharmaceutical composition containing them as an active ingredient
EP0277917A3 (de) * 1987-02-04 1990-03-28 Ciba-Geigy Ag Bestimmte Derivate von Adenosin-5'-carboxamid
IL86007A0 (en) * 1987-04-09 1988-09-30 Wellcome Found 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them
IL86009A (en) * 1987-04-10 1991-09-16 Us Health Liposome-encapsulated phosphorylated nucleosides for treatment of retroviral diseases
DE68929321T2 (de) * 1988-06-09 2002-05-08 Temple University Of The Commonwealth System Of Higher Education, Philadelphia Therapeutische Anwendungen von 2',5'-Oligoadenylat-Derivaten
US5292725A (en) * 1988-08-25 1994-03-08 Prendergast Patrick T Administering particular compounds against various parasites, mycoplasmas, other indications and other infections

Also Published As

Publication number Publication date
KR900002786A (ko) 1990-03-23
US5681831A (en) 1997-10-28
JPH02237996A (ja) 1990-09-20
DK418489A (da) 1990-02-26
AU636574B2 (en) 1993-05-06
IE882585L (en) 1990-02-25
FI893948L (fi) 1990-02-26
IL91415A0 (en) 1990-04-29
JP3237836B2 (ja) 2001-12-10
FI893948A0 (fi) 1989-08-23
FI893948A7 (fi) 1990-02-26
OA09427A (en) 1992-10-15
AU4025689A (en) 1990-03-01
CA1339854C (en) 1998-05-05
EP0355825A3 (de) 1991-12-27
DK418489D0 (da) 1989-08-24
ZA896450B (en) 1991-04-24
EP0355825A2 (de) 1990-02-28

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RH1 Patent not in force