IL92165A - התקן לביצוע מדידות של תופעות אלקטרוכימילומינסצנטיות - Google Patents
התקן לביצוע מדידות של תופעות אלקטרוכימילומינסצנטיותInfo
- Publication number
- IL92165A IL92165A IL9216589A IL9216589A IL92165A IL 92165 A IL92165 A IL 92165A IL 9216589 A IL9216589 A IL 9216589A IL 9216589 A IL9216589 A IL 9216589A IL 92165 A IL92165 A IL 92165A
- Authority
- IL
- Israel
- Prior art keywords
- voltage waveform
- control signal
- pulse width
- digital
- sample fluid
- Prior art date
Links
- 238000005259 measurement Methods 0.000 title claims abstract description 38
- 239000012530 fluid Substances 0.000 claims abstract description 41
- 238000000034 method Methods 0.000 claims abstract description 17
- 230000004044 response Effects 0.000 claims description 35
- 230000005670 electromagnetic radiation Effects 0.000 claims description 12
- 230000005855 radiation Effects 0.000 claims description 12
- 230000008569 process Effects 0.000 abstract description 7
- 230000001939 inductive effect Effects 0.000 abstract description 4
- 239000000523 sample Substances 0.000 description 31
- 210000004027 cell Anatomy 0.000 description 29
- 239000012491 analyte Substances 0.000 description 10
- 229920005994 diacetyl cellulose Polymers 0.000 description 8
- 238000010586 diagram Methods 0.000 description 8
- 239000000243 solution Substances 0.000 description 6
- 239000007853 buffer solution Substances 0.000 description 5
- 239000000376 reactant Substances 0.000 description 5
- 239000012488 sample solution Substances 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 238000010276 construction Methods 0.000 description 3
- 230000007246 mechanism Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000000159 protein binding assay Methods 0.000 description 3
- 230000001960 triggered effect Effects 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000005518 electrochemistry Effects 0.000 description 2
- 238000004020 luminiscence type Methods 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 238000001429 visible spectrum Methods 0.000 description 2
- 206010065929 Cardiovascular insufficiency Diseases 0.000 description 1
- 102000006830 Luminescent Proteins Human genes 0.000 description 1
- 108010047357 Luminescent Proteins Proteins 0.000 description 1
- 229910021607 Silver chloride Inorganic materials 0.000 description 1
- 238000004164 analytical calibration Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003638 chemical reducing agent Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 210000004188 enterochromaffin-like cell Anatomy 0.000 description 1
- 230000005281 excited state Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000819 phase cycle Methods 0.000 description 1
- 238000006479 redox reaction Methods 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03K—PULSE TECHNIQUE
- H03K4/00—Generating pulses having essentially a finite slope or stepped portions
- H03K4/02—Generating pulses having essentially a finite slope or stepped portions having stepped portions, e.g. staircase waveform
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/66—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
-
- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03K—PULSE TECHNIQUE
- H03K4/00—Generating pulses having essentially a finite slope or stepped portions
- H03K4/02—Generating pulses having essentially a finite slope or stepped portions having stepped portions, e.g. staircase waveform
- H03K4/026—Generating pulses having essentially a finite slope or stepped portions having stepped portions, e.g. staircase waveform using digital techniques
Landscapes
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Manufacture Of Electron Tubes, Discharge Lamp Vessels, Lead-In Wires, And The Like (AREA)
- Control Of El Displays (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/267,234 US5061445A (en) | 1988-11-03 | 1988-11-03 | Apparatus for conducting measurements of electrochemiluminescent phenomena |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL92165A0 IL92165A0 (en) | 1990-07-12 |
| IL92165A true IL92165A (he) | 1994-06-24 |
Family
ID=23017898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9216589A IL92165A (he) | 1988-11-03 | 1989-10-31 | התקן לביצוע מדידות של תופעות אלקטרוכימילומינסצנטיות |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5061445A (he) |
| EP (1) | EP0441880B1 (he) |
| JP (1) | JPH076912B2 (he) |
| KR (1) | KR900702650A (he) |
| AT (1) | ATE143497T1 (he) |
| AU (1) | AU637070B2 (he) |
| CA (1) | CA2002100C (he) |
| DE (1) | DE68927263T2 (he) |
| IL (1) | IL92165A (he) |
| MX (1) | MX170953B (he) |
| WO (1) | WO1990005411A1 (he) |
| ZA (1) | ZA898287B (he) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6054296A (en) * | 1988-10-24 | 2000-04-25 | Symbicom Ab | 66 kDa antigen from Borrelia |
| US5147806A (en) * | 1988-04-29 | 1992-09-15 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescence measurements |
| US6881589B1 (en) | 1987-04-30 | 2005-04-19 | Bioveris Corporation | Electrochemiluminescent localizable complexes for assay compositions |
| US5935779A (en) * | 1988-11-03 | 1999-08-10 | Igen International Inc. | Methods for improved particle electrochemiluminescence assay |
| US5779976A (en) * | 1988-11-03 | 1998-07-14 | Igen International, Inc. | Apparatus for improved luminescence assays |
| US5296191A (en) * | 1988-11-03 | 1994-03-22 | Igen, Inc. | Method and apparatus for conducting electrochemiluminescent measurements |
| US5962218A (en) * | 1988-11-03 | 1999-10-05 | Igen International Inc. | Methods and apparatus for improved luminescence assays |
| IL100867A (en) * | 1991-02-06 | 1995-12-08 | Igen Inc | Method and apparatus for improved luminescence assays |
| ZA92803B (en) | 1991-02-06 | 1992-11-25 | Igen Inc | Method and apparatus for magnetic microparticulate based luminescene asay including plurality of magnets |
| IL100866A (en) * | 1991-02-06 | 1995-10-31 | Igen Inc | Method and apparatus for magnetic microparticulate based luminescence assay including plurality of magnets |
| US5578498A (en) | 1991-05-22 | 1996-11-26 | Behringwerke Ag | Metal chelate containing compositions for use in chemiluminescent assays |
| US6251581B1 (en) * | 1991-05-22 | 2001-06-26 | Dade Behring Marburg Gmbh | Assay method utilizing induced luminescence |
| ATE184320T1 (de) * | 1991-07-10 | 1999-09-15 | Igen Int Inc | Verfahren für verbesserte lumineszenz-assays unter verwendung von teilchenkonzentration und chemilumineszenznachweis |
| ZA929351B (en) * | 1991-12-11 | 1993-06-04 | Igen Inc | Electrochemiluminescent label for DNA assays. |
| WO1994025853A1 (de) * | 1993-05-03 | 1994-11-10 | Boehringer Mannheim Gmbh | Elektrochemilumineszenzverfahren |
| US5466416A (en) * | 1993-05-14 | 1995-11-14 | Ghaed; Ali | Apparatus and methods for carrying out electrochemiluminescence test measurements |
| WO1996005501A1 (en) | 1993-05-14 | 1996-02-22 | Igen, Inc. | Apparatus and methods for carrying out electrochemiluminescence test measurements |
| JPH10504105A (ja) * | 1994-08-15 | 1998-04-14 | イゲン，インコーポレーテッド | 電気化学ルミネセンスの試験測定を実施する装置および方法 |
| US20010003647A1 (en) * | 1995-06-07 | 2001-06-14 | Ji Sun | Coreatant-including electrochemiluminescent compounds, methods, systems and kits utilizing same |
| US5610075A (en) * | 1995-01-17 | 1997-03-11 | Stahl-Rees; Marianne | Competitive electrochemiluminescence assays for endotoxins using a ruthenium label |
| AU2929602A (en) * | 1995-03-10 | 2002-05-23 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| US6673533B1 (en) | 1995-03-10 | 2004-01-06 | Meso Scale Technologies, Llc. | Multi-array multi-specific electrochemiluminescence testing |
| US6207369B1 (en) * | 1995-03-10 | 2001-03-27 | Meso Scale Technologies, Llc | Multi-array, multi-specific electrochemiluminescence testing |
| JPH11502617A (ja) | 1995-03-10 | 1999-03-02 | メソ スケール テクノロジーズ，エルエルシー | 多重アレイの多重特異的な電気化学発光試験 |
| US6140045A (en) * | 1995-03-10 | 2000-10-31 | Meso Scale Technologies | Multi-array, multi-specific electrochemiluminescence testing |
| JPH08297813A (ja) * | 1995-04-27 | 1996-11-12 | Nec Corp | 磁気ヘッドスライダ及びその製造方法 |
| US5663728A (en) * | 1995-05-18 | 1997-09-02 | Hughes Aircraft Company | Digital-to-analog converted (DAC) and method that set waveform rise and fall times to produce an analog waveform that approximates a piecewise linear waveform to reduce spectral distortion |
| CA2223027A1 (en) | 1995-06-07 | 1996-12-19 | Igen, Inc. | Electrochemiluminescent enzyme immunoassay |
| US6099760A (en) * | 1995-06-07 | 2000-08-08 | Igen, Inc. | Hydrogen peroxide based ECL |
| WO1996041155A1 (en) * | 1995-06-07 | 1996-12-19 | Igen, Inc. | An improved electrochemiluminescence method |
| CA2276462C (en) | 1996-12-31 | 2007-06-12 | High Throughput Genomics, Inc. | Multiplexed molecular analysis system apparatus and method |
| US6200531B1 (en) * | 1998-05-11 | 2001-03-13 | Igen International, Inc. | Apparatus for carrying out electrochemiluminescence test measurements |
| US6780617B2 (en) | 2000-12-29 | 2004-08-24 | Chen & Chen, Llc | Sample processing device and method |
| US7799521B2 (en) * | 1998-06-24 | 2010-09-21 | Chen & Chen, Llc | Thermal cycling |
| JP4321738B2 (ja) | 1998-06-24 | 2009-08-26 | チェン アンド チェン エルエルシー | 液体試料試験システム |
| US7141436B2 (en) * | 1999-11-03 | 2006-11-28 | Science And Technology Corp. | Immunoassay and reagents and kits for performing the same |
| GB0103765D0 (en) * | 2001-02-15 | 2001-04-04 | Affitech As | Assay |
| CA2460192C (en) | 2001-09-11 | 2011-04-19 | Iquum, Inc. | Sample vessels |
| KR20050013592A (ko) * | 2002-06-20 | 2005-02-04 | 아이젠인터내셔널인코포레이티드 | 전기화학발광 유동 셀 및 유동 셀 성분 |
| US7000870B2 (en) * | 2002-11-07 | 2006-02-21 | Aerion Corporation | Laminar flow wing for transonic cruise |
| CA2515075C (en) | 2003-02-05 | 2012-10-02 | Iquum, Inc. | Sample processing |
| US7238536B1 (en) * | 2004-03-22 | 2007-07-03 | Florida State University Research Foundation, Inc. | Controlled transport through multiple reversible interaction point membranes |
| KR101026248B1 (ko) * | 2004-09-21 | 2011-03-31 | 페어차일드코리아반도체 주식회사 | 역률 보상 회로 |
| JP2008521007A (ja) * | 2004-11-17 | 2008-06-19 | バイオヴェリス コーポレイション | 電気化学発光測定法 |
| US20060275841A1 (en) * | 2004-12-20 | 2006-12-07 | Martin Blankfard | Assay method and apparatus with reduced sample matrix effects |
| JP5590796B2 (ja) | 2005-06-03 | 2014-09-17 | ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システム | 電気化学および単一ファラデー電極による電気化学発光 |
| WO2007002580A2 (en) * | 2005-06-23 | 2007-01-04 | Bioveris Corporation | Diagnostic as say system with multi -well reagent container |
| US7402805B1 (en) | 2005-08-22 | 2008-07-22 | The United States Of America As Represented By The Secretary Of The Navy | Device for the in-situ measurement of acoustically stimulated bioluminescence |
| PT2271938E (pt) | 2008-04-11 | 2014-05-09 | Univ Texas | Método e aparelho de amplificação de quimiluminescênci electrogerada por nanopartículas |
| AU2009244904B2 (en) | 2008-05-08 | 2014-04-17 | Board Of Regents Of The University Of Texas System | Luminescent nanostructured materials for use in electrogenerated chemiluminescence |
| ITTO20100212A1 (it) * | 2010-03-19 | 2011-09-20 | Cyanagen S R L | "procedimento per la generazione e l'analisi di segnali di elettrochemiluminescenza e relativo sistema" |
| WO2012154272A1 (en) | 2011-02-25 | 2012-11-15 | Wellstat Diagnostics, Llc | Assays for detecting enzymatic activity |
| US9625465B2 (en) | 2012-05-15 | 2017-04-18 | Defined Diagnostics, Llc | Clinical diagnostic systems |
| US9213043B2 (en) | 2012-05-15 | 2015-12-15 | Wellstat Diagnostics, Llc | Clinical diagnostic system including instrument and cartridge |
| US9075042B2 (en) | 2012-05-15 | 2015-07-07 | Wellstat Diagnostics, Llc | Diagnostic systems and cartridges |
| JP6239243B2 (ja) | 2013-02-08 | 2017-11-29 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 自動分析装置 |
| CN104297231A (zh) * | 2014-10-30 | 2015-01-21 | 中国科学院长春应用化学研究所 | 一种电化学发光光谱仪 |
| FI20175623A1 (en) * | 2017-06-29 | 2018-12-30 | Labmaster Oy | A method and devices for adaptive measuring of electrochemiluminescence |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7001235A (he) * | 1970-01-29 | 1971-08-02 | ||
| US3868534A (en) * | 1972-11-29 | 1975-02-25 | Bell Canada Northern Electric | Electrochemiluminescent device having a mixed solvent |
| FR2247732A1 (he) * | 1973-10-16 | 1975-05-09 | Accumulateurs Fixes | |
| US3963928A (en) * | 1974-05-17 | 1976-06-15 | Thermo Electron Corporation | Multiple chamber chemiluminescent analyzer |
| US3984688A (en) * | 1975-04-21 | 1976-10-05 | Source Gas Analyzers, Inc. | Monitor for detection of chemiluminescent reactions |
| JPS5843621B2 (ja) * | 1975-07-18 | 1983-09-28 | トキコ株式会社 | 密閉型シリンダ装置 |
| US4204037A (en) * | 1978-04-04 | 1980-05-20 | Nasa | Method and automated apparatus for detecting coliform organisms |
| US4236895A (en) * | 1979-06-11 | 1980-12-02 | Meloy Laboratories, Inc. | Analytical apparatus and method employing purified ozone |
| US4280815A (en) * | 1979-06-18 | 1981-07-28 | Technicon Instruments Corporation | Electrochemiluminescent immunoassay and apparatus therefor |
| DE3013765A1 (de) * | 1980-04-10 | 1981-10-15 | Philips Patentverwaltung Gmbh, 2000 Hamburg | Detektroranordnung, insbesondere fuer die fluessigkeitschromatografie |
| US4303410A (en) * | 1980-11-03 | 1981-12-01 | The United States Of America As Represented By The Secretary Of The Navy | Light burst activity analyzer |
| DE3260566D1 (en) * | 1981-06-12 | 1984-09-20 | Tour & Andersson Ab | Arrangement in climatization systems |
| US4468638A (en) * | 1982-02-11 | 1984-08-28 | The Bendix Corporation | Linear sweep frequency modulator for FM/CW radio altimeter |
| US4634574A (en) * | 1983-01-31 | 1987-01-06 | Iowa State Research Foundation, Inc. | Apparatus for use in sulfide chemiluminescence detection |
| US5238808A (en) * | 1984-10-31 | 1993-08-24 | Igen, Inc. | Luminescent metal chelate labels and means for detection |
| US4721601A (en) * | 1984-11-23 | 1988-01-26 | Massachusetts Institute Of Technology | Molecule-based microelectronic devices |
| JPS61247962A (ja) * | 1985-04-26 | 1986-11-05 | Hamamatsu Photonics Kk | 細胞診断装置 |
| US4822564A (en) * | 1985-07-02 | 1989-04-18 | Sensors, Inc. | Chemiluminescent gas analyzer for measuring the oxides of nitrogen |
| US4689305A (en) * | 1986-03-24 | 1987-08-25 | The United States Of America As Represented By The Secretary Of The Navy | Solid-state photometer circuit |
| GB8630136D0 (en) * | 1986-12-17 | 1987-01-28 | Grand Metropolitan Innovation | Luminometer apparatus |
| JPH0678985B2 (ja) * | 1987-03-06 | 1994-10-05 | ティーディーケイ株式会社 | 電気化学的光学特性検出用電極および電気化学的光学特性検出方法 |
| JPH01247962A (ja) * | 1988-03-29 | 1989-10-03 | Hisaka Works Ltd | ヒートポンプ |
-
1988
- 1988-11-03 US US07/267,234 patent/US5061445A/en not_active Expired - Lifetime
-
1989
- 1989-10-31 ZA ZA898287A patent/ZA898287B/xx unknown
- 1989-10-31 AU AU46267/89A patent/AU637070B2/en not_active Ceased
- 1989-10-31 KR KR1019900701439A patent/KR900702650A/ko not_active Ceased
- 1989-10-31 AT AT89912913T patent/ATE143497T1/de not_active IP Right Cessation
- 1989-10-31 JP JP2500333A patent/JPH076912B2/ja not_active Expired - Lifetime
- 1989-10-31 WO PCT/US1989/004854 patent/WO1990005411A1/en not_active Ceased
- 1989-10-31 EP EP89912913A patent/EP0441880B1/en not_active Expired - Lifetime
- 1989-10-31 IL IL9216589A patent/IL92165A/he active IP Right Grant
- 1989-10-31 DE DE68927263T patent/DE68927263T2/de not_active Expired - Lifetime
- 1989-11-02 CA CA002002100A patent/CA2002100C/en not_active Expired - Lifetime
- 1989-11-03 MX MX018214A patent/MX170953B/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU4626789A (en) | 1990-05-28 |
| ATE143497T1 (de) | 1996-10-15 |
| CA2002100C (en) | 1994-12-06 |
| ZA898287B (en) | 1990-07-25 |
| MX170953B (es) | 1993-09-22 |
| DE68927263D1 (de) | 1996-10-31 |
| EP0441880A4 (en) | 1992-11-25 |
| IL92165A0 (en) | 1990-07-12 |
| JPH04502207A (ja) | 1992-04-16 |
| KR900702650A (ko) | 1990-12-08 |
| DE68927263T2 (de) | 1997-02-20 |
| WO1990005411A1 (en) | 1990-05-17 |
| JPH076912B2 (ja) | 1995-01-30 |
| US5061445A (en) | 1991-10-29 |
| CA2002100A1 (en) | 1990-05-03 |
| EP0441880A1 (en) | 1991-08-21 |
| AU637070B2 (en) | 1993-05-20 |
| EP0441880B1 (en) | 1996-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed |