IL92527A - Opthalmic pharmaceutical composition for glaucoma therapy - Google Patents

Opthalmic pharmaceutical composition for glaucoma therapy

Info

Publication number
IL92527A
IL92527A IL9252789A IL9252789A IL92527A IL 92527 A IL92527 A IL 92527A IL 9252789 A IL9252789 A IL 9252789A IL 9252789 A IL9252789 A IL 9252789A IL 92527 A IL92527 A IL 92527A
Authority
IL
Israel
Prior art keywords
exchange resin
cation exchange
basic active
present
composition
Prior art date
Application number
IL9252789A
Other languages
English (en)
Original Assignee
Alcon Lab Inc Fort Worth Tex U
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27508398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL92527(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to US07/154,514 priority Critical patent/US4911920A/en
Priority to AU45753/89A priority patent/AU621692B2/en
Priority to IL9252789A priority patent/IL92527A/en
Priority to CA002004468A priority patent/CA2004468C/fr
Priority to EP89312590A priority patent/EP0429732B1/fr
Application filed by Alcon Lab Inc Fort Worth Tex U filed Critical Alcon Lab Inc Fort Worth Tex U
Priority to DE68913979T priority patent/DE68913979T2/de
Priority to JP1321616A priority patent/JPH0725698B2/ja
Priority claimed from JP1321616A external-priority patent/JPH0725698B2/ja
Publication of IL92527A publication Critical patent/IL92527A/en
Priority to US08/334,512 priority patent/US5554367A/en
Priority to US08/396,284 priority patent/US5635172A/en
Priority to HK135695A priority patent/HK135695A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL9252789A 1984-10-31 1989-12-01 Opthalmic pharmaceutical composition for glaucoma therapy IL92527A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
US07/154,514 US4911920A (en) 1986-07-30 1988-02-05 Sustained release, comfort formulation for glaucoma therapy
AU45753/89A AU621692B2 (en) 1986-07-30 1989-11-30 Sustained release, comfort formulation for glaucoma therapy
DE68913979T DE68913979T2 (de) 1988-02-05 1989-12-01 Kationenaustauscherharze und carboxylgruppenhaltige Kunstharze enthaltende Arzneizubereitungen mit verzögerter Wirkstofffreisetzung.
CA002004468A CA2004468C (fr) 1988-02-05 1989-12-01 Gouttes lubrifiantes a liberation soutenue pour le traitement du glaucome
EP89312590A EP0429732B1 (fr) 1986-07-30 1989-12-01 Compositions à libération prolongée à base de résines échangeuses d'ions cationiques et de polymères polycarboxyliques
IL9252789A IL92527A (en) 1988-02-05 1989-12-01 Opthalmic pharmaceutical composition for glaucoma therapy
JP1321616A JPH0725698B2 (ja) 1984-10-31 1989-12-13 持続的放出性を有し快適に適用できる緑内障治療用の処方物
US08/334,512 US5554367A (en) 1984-10-31 1994-11-04 Compositions for treatment of glaucoma
US08/396,284 US5635172A (en) 1984-10-31 1995-02-27 Sustained release comfort formulation for glaucoma therapy
HK135695A HK135695A (en) 1986-07-30 1995-08-24 Sustained-release compositions containing cation exchange resins and polycarboxylic polymers

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US07/154,514 US4911920A (en) 1986-07-30 1988-02-05 Sustained release, comfort formulation for glaucoma therapy
CA002004468A CA2004468C (fr) 1988-02-05 1989-12-01 Gouttes lubrifiantes a liberation soutenue pour le traitement du glaucome
IL9252789A IL92527A (en) 1988-02-05 1989-12-01 Opthalmic pharmaceutical composition for glaucoma therapy
JP1321616A JPH0725698B2 (ja) 1984-10-31 1989-12-13 持続的放出性を有し快適に適用できる緑内障治療用の処方物
HK135695A HK135695A (en) 1986-07-30 1995-08-24 Sustained-release compositions containing cation exchange resins and polycarboxylic polymers

Publications (1)

Publication Number Publication Date
IL92527A true IL92527A (en) 1994-02-27

Family

ID=27508398

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9252789A IL92527A (en) 1984-10-31 1989-12-01 Opthalmic pharmaceutical composition for glaucoma therapy

Country Status (7)

Country Link
US (2) US4911920A (fr)
EP (1) EP0429732B1 (fr)
AU (1) AU621692B2 (fr)
CA (1) CA2004468C (fr)
DE (1) DE68913979T2 (fr)
HK (1) HK135695A (fr)
IL (1) IL92527A (fr)

Families Citing this family (319)

* Cited by examiner, † Cited by third party
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US5660851A (en) * 1989-12-26 1997-08-26 Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem Ocular inserts
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US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
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US5635172A (en) 1997-06-03
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EP0429732A1 (fr) 1991-06-05
EP0429732B1 (fr) 1994-03-16
AU621692B2 (en) 1992-03-19
DE68913979D1 (de) 1994-04-21
US4911920A (en) 1990-03-27
AU4575389A (en) 1991-08-01

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