IL92970A - Substituted 3,5-dihydroxy-7-(pyrido(2,3-d) pyrimidin-6-yl) alkanoic acids and 6-alkenoic acids, their preparation and pharmaceutical compositions containing them - Google Patents

Substituted 3,5-dihydroxy-7-(pyrido(2,3-d) pyrimidin-6-yl) alkanoic acids and 6-alkenoic acids, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL92970A
IL92970A IL9297090A IL9297090A IL92970A IL 92970 A IL92970 A IL 92970A IL 9297090 A IL9297090 A IL 9297090A IL 9297090 A IL9297090 A IL 9297090A IL 92970 A IL92970 A IL 92970A
Authority
IL
Israel
Prior art keywords
carbon atoms
chain
straight
group
branched alkyl
Prior art date
Application number
IL9297090A
Other languages
English (en)
Other versions
IL92970A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3900363A external-priority patent/DE3900363A1/de
Priority claimed from IT8921215A external-priority patent/IT8921215A0/it
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL92970A0 publication Critical patent/IL92970A0/xx
Publication of IL92970A publication Critical patent/IL92970A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
IL9297090A 1989-01-07 1990-01-04 Substituted 3,5-dihydroxy-7-(pyrido(2,3-d) pyrimidin-6-yl) alkanoic acids and 6-alkenoic acids, their preparation and pharmaceutical compositions containing them IL92970A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3900363A DE3900363A1 (de) 1989-01-07 1989-01-07 Neue substituierte pyrido(2,3,-d)pyrimidine
IT8921215A IT8921215A0 (it) 1989-07-18 1989-07-18 Pirido(2,3 d)pirimidine sostituite.

Publications (2)

Publication Number Publication Date
IL92970A0 IL92970A0 (en) 1990-09-17
IL92970A true IL92970A (en) 1994-01-25

Family

ID=25876617

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9297090A IL92970A (en) 1989-01-07 1990-01-04 Substituted 3,5-dihydroxy-7-(pyrido(2,3-d) pyrimidin-6-yl) alkanoic acids and 6-alkenoic acids, their preparation and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US5075311A (fr)
EP (1) EP0378850B1 (fr)
JP (1) JPH02247179A (fr)
KR (1) KR900011768A (fr)
CN (1) CN1043938A (fr)
AU (1) AU618158B2 (fr)
CA (1) CA2007233A1 (fr)
DE (1) DE58907412D1 (fr)
DK (1) DK3290A (fr)
ES (1) ES2063107T3 (fr)
FI (1) FI900038A7 (fr)
HU (1) HUT53640A (fr)
IE (1) IE900058L (fr)
IL (1) IL92970A (fr)
NO (1) NO895217L (fr)
NZ (1) NZ232013A (fr)
PT (1) PT92793A (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145959A (en) * 1989-07-18 1992-09-08 Bayer Aktiengesellschaft Substituted pyrido (2,3-d) pyrimidines as intermediates
DE4035479A1 (de) * 1990-11-08 1992-05-14 Basf Ag Substituierte pyrido (2,3-d)pyrimidin-2,4(1h,3h)-dione
AR008789A1 (es) 1996-07-31 2000-02-23 Bayer Corp Piridinas y bifenilos substituidos
CN1268137A (zh) * 1997-07-03 2000-09-27 杜邦药品公司 治疗神经失调的咪唑并嘧啶和咪唑并吡啶
US6124463A (en) * 1998-07-02 2000-09-26 Dupont Pharmaceuticals Benzimidazoles as corticotropin release factor antagonists
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
US7420059B2 (en) 2003-11-20 2008-09-02 Bristol-Myers Squibb Company HMG-CoA reductase inhibitors and method
WO2006019965A2 (fr) * 2004-07-16 2006-02-23 Takeda San Diego, Inc. Inhibiteurs de la dipeptidyl peptidase
EP2266984A1 (fr) * 2009-06-26 2010-12-29 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Pyrido[2,3-d]pyrimidines en tant qu' antagoniste du Wnt pour le traitement du cancer et de l'arthrite
CN108164517A (zh) * 2018-02-12 2018-06-15 李化绪 (2-甲基环己烷-1-基)亚氨基类化合物及其在高脂血症药物中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE114027C (fr) *
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
IL60219A (en) * 1979-06-15 1985-05-31 Merck & Co Inc Hypocholesteremic fermentation products of the hmg-coa reductase inhibitor type,their preparation and pharmaceutical compositions containing them
US4613610A (en) * 1984-06-22 1986-09-23 Sandoz Pharmaceuticals Corp. Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
US4761419A (en) * 1987-12-07 1988-08-02 Warner-Lambert Company 6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis

Also Published As

Publication number Publication date
IE900058L (en) 1990-07-07
NO895217L (no) 1990-07-09
FI900038A7 (fi) 1990-07-08
ES2063107T3 (es) 1995-01-01
EP0378850A3 (fr) 1991-09-11
DE58907412D1 (de) 1994-05-11
US5075311A (en) 1991-12-24
JPH02247179A (ja) 1990-10-02
NZ232013A (en) 1991-11-26
AU618158B2 (en) 1991-12-12
DK3290D0 (da) 1990-01-05
EP0378850B1 (fr) 1994-04-06
AU4698889A (en) 1990-07-12
HUT53640A (en) 1990-11-28
IL92970A0 (en) 1990-09-17
KR900011768A (ko) 1990-08-02
EP0378850A2 (fr) 1990-07-25
HU900049D0 (en) 1990-03-28
FI900038A0 (fi) 1990-01-04
CA2007233A1 (fr) 1990-07-07
DK3290A (da) 1990-07-08
PT92793A (pt) 1990-07-31
NO895217D0 (no) 1989-12-22
CN1043938A (zh) 1990-07-18

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Legal Events

Date Code Title Description
RH Patent void