IL93881A - Pre-filled injection device - Google Patents

Pre-filled injection device

Info

Publication number: IL93881A
Authority: IL; Israel
Prior art keywords: injection; barrel; rubber; diazepam; liquid
Prior art date: 1989-03-28

Application number

IL9388190A

Other languages

English (en)

Hebrew (he)

Other versions

IL93881A0 (en

Original Assignee

Duphar Int Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-28

Filing date

1990-03-26

Publication date

1994-10-07

1990-03-26 Application filed by Duphar Int Res filed Critical Duphar Int Res

1990-12-23 Publication of IL93881A0 publication Critical patent/IL93881A0/xx

1994-10-07 Publication of IL93881A publication Critical patent/IL93881A/en

Links

238000002347 injection Methods 0.000 title claims abstract description 72
239000007924 injection Substances 0.000 title claims abstract description 72
AAOVKJBEBIDNHE-UHFFFAOYSA-N diazepam Chemical compound N=1CC(=O)N(C)C2=CC=C(Cl)C=C2C=1C1=CC=CC=C1 AAOVKJBEBIDNHE-UHFFFAOYSA-N 0.000 claims abstract description 43
229960003529 diazepam Drugs 0.000 claims abstract description 43
239000007788 liquid Substances 0.000 claims abstract description 42
229920001971 elastomer Polymers 0.000 claims abstract description 39
239000005060 rubber Substances 0.000 claims abstract description 38
238000009472 formulation Methods 0.000 claims abstract description 32
239000000203 mixture Substances 0.000 claims abstract description 32
238000007789 sealing Methods 0.000 claims abstract description 28
-1 bromobutyl Chemical group 0.000 claims abstract description 18
229920005557 bromobutyl Polymers 0.000 claims abstract description 17
229920005556 chlorobutyl Polymers 0.000 description 9
230000007423 decrease Effects 0.000 description 8
230000002035 prolonged effect Effects 0.000 description 7
239000003814 drug Substances 0.000 description 6
238000007911 parenteral administration Methods 0.000 description 4
239000000126 substance Substances 0.000 description 4
230000001225 therapeutic effect Effects 0.000 description 4
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
230000006866 deterioration Effects 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
239000003958 nerve gas Substances 0.000 description 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
VQTUBCCKSQIDNK-UHFFFAOYSA-N Isobutene Chemical compound CC(C)=C VQTUBCCKSQIDNK-UHFFFAOYSA-N 0.000 description 2
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
230000001627 detrimental effect Effects 0.000 description 2
230000000694 effects Effects 0.000 description 2
238000002474 experimental method Methods 0.000 description 2
239000007789 gas Substances 0.000 description 2
239000011521 glass Substances 0.000 description 2
239000012669 liquid formulation Substances 0.000 description 2
210000003205 muscle Anatomy 0.000 description 2
239000001301 oxygen Substances 0.000 description 2
229910052760 oxygen Inorganic materials 0.000 description 2
239000002574 poison Substances 0.000 description 2
231100000614 poison Toxicity 0.000 description 2
238000002203 pretreatment Methods 0.000 description 2
230000001624 sedative effect Effects 0.000 description 2
239000000243 solution Substances 0.000 description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
229930003347 Atropine Natural products 0.000 description 1
239000005711 Benzoic acid Substances 0.000 description 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
RKUNBYITZUJHSG-UHFFFAOYSA-N Hyosciamin-hydrochlorid Natural products CN1C(C2)CCC1CC2OC(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-UHFFFAOYSA-N 0.000 description 1
206010033799 Paralysis Diseases 0.000 description 1
XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
208000005392 Spasm Diseases 0.000 description 1
238000004458 analytical method Methods 0.000 description 1
RKUNBYITZUJHSG-SPUOUPEWSA-N atropine Chemical compound O([C@H]1C[C@H]2CC[C@@H](C1)N2C)C(=O)C(CO)C1=CC=CC=C1 RKUNBYITZUJHSG-SPUOUPEWSA-N 0.000 description 1
229960000396 atropine Drugs 0.000 description 1
229940049706 benzodiazepine Drugs 0.000 description 1
150000001557 benzodiazepines Chemical class 0.000 description 1
235000010233 benzoic acid Nutrition 0.000 description 1
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
229910052794 bromium Inorganic materials 0.000 description 1
229920005549 butyl rubber Polymers 0.000 description 1
239000006227 byproduct Substances 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
239000000470 constituent Substances 0.000 description 1
229920001577 copolymer Polymers 0.000 description 1
230000006378 damage Effects 0.000 description 1
239000000806 elastomer Substances 0.000 description 1
239000000839 emulsion Substances 0.000 description 1
230000002349 favourable effect Effects 0.000 description 1
239000000945 filler Substances 0.000 description 1
238000004128 high performance liquid chromatography Methods 0.000 description 1
230000000147 hypnotic effect Effects 0.000 description 1
230000007774 longterm Effects 0.000 description 1
238000012423 maintenance Methods 0.000 description 1
239000000463 material Substances 0.000 description 1
239000003158 myorelaxant agent Substances 0.000 description 1
HIGRLDNHDGYWQJ-UHFFFAOYSA-P obidoxime Chemical compound C1=CC(=C[NH+]=O)C=CN1COCN1C=CC(=C[NH+]=O)C=C1 HIGRLDNHDGYWQJ-UHFFFAOYSA-P 0.000 description 1
229960004429 obidoxime Drugs 0.000 description 1
239000003921 oil Substances 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
230000000079 pharmacotherapeutic effect Effects 0.000 description 1
WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
239000000049 pigment Substances 0.000 description 1
238000004321 preservation Methods 0.000 description 1
230000002040 relaxant effect Effects 0.000 description 1
239000000932 sedative agent Substances 0.000 description 1
229910052710 silicon Inorganic materials 0.000 description 1
239000010703 silicon Substances 0.000 description 1
WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
235000010234 sodium benzoate Nutrition 0.000 description 1
239000004299 sodium benzoate Substances 0.000 description 1
238000013112 stability test Methods 0.000 description 1
230000001954 sterilising effect Effects 0.000 description 1
229920002994 synthetic fiber Polymers 0.000 description 1
MLGCXEBRWGEOQX-UHFFFAOYSA-N tetradifon Chemical compound C1=CC(Cl)=CC=C1S(=O)(=O)C1=CC(Cl)=C(Cl)C=C1Cl MLGCXEBRWGEOQX-UHFFFAOYSA-N 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
238000004073 vulcanization Methods 0.000 description 1
238000005406 washing Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
- A61J1/062—Carpules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M2005/1787—Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/206—With automatic needle insertion
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M2005/3132—Syringe barrels having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
- A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Engineering & Computer Science (AREA)
Vascular Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Infusion, Injection, And Reservoir Apparatuses (AREA)
Medicinal Preparation (AREA)
Fuel-Injection Apparatus (AREA)
Cultivation Of Plants (AREA)
Injection Moulding Of Plastics Or The Like (AREA)

IL9388190A 1989-03-28 1990-03-26 Pre-filled injection device IL93881A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL8900747		1989-03-28

Publications (2)

Publication Number	Publication Date
IL93881A0 IL93881A0 (en)	1990-12-23
IL93881A true IL93881A (en)	1994-10-07

Family

ID=19854360

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL9388190A IL93881A (en)	1989-03-28	1990-03-26	Pre-filled injection device

Country Status (9)

Country	Link
US (1)	US5383864A (ja)
EP (1)	EP0390244B1 (ja)
JP (1)	JPH02283377A (ja)
AT (1)	ATE84205T1 (ja)
CA (1)	CA2012919A1 (ja)
DE (1)	DE69000716T2 (ja)
DK (1)	DK0390244T3 (ja)
ES (1)	ES2036885T3 (ja)
IL (1)	IL93881A (ja)

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FR2756811B1 (fr) *	1996-12-06	1999-02-05	Valois	Dispositif de distribution de produit fluide du type bicomposant
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US20020139088A1 (en) *	2001-03-08	2002-10-03	Archie Woodworth	Polymeric syringe body and stopper
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GB0304823D0 (en)	2003-03-03	2003-04-09	Dca Internat Ltd	Improvements in and relating to a pen-type injector
US8476010B2 (en)	2003-07-10	2013-07-02	App Pharmaceuticals Llc	Propofol formulations with non-reactive container closures
GB0414054D0 (en)	2004-06-23	2004-07-28	Owen Mumford Ltd	Improvements relating to automatic injection devices
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US8361026B2 (en)	2005-02-01	2013-01-29	Intelliject, Inc.	Apparatus and methods for self-administration of vaccines and other medicaments
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US9022980B2 (en)	2005-02-01	2015-05-05	Kaleo, Inc.	Medical injector simulation device
DK2058020T3 (da)	2005-02-01	2013-01-07	Intelliject Inc	Indretning til indgivelse af lægemiddel
CN101257940B (zh) *	2005-04-13	2011-05-18	科尔公司	带有可膨胀密封件的注射筒活塞罩
NZ562593A (en)	2005-05-02	2011-05-27	Int Paper Co	Ligno cellulosic materials and the products made therefrom, using an oxidizing agent with a transition metal catalyst
US20070166187A1 (en) *	2006-01-18	2007-07-19	Song Jing F	Stabilization of paricalcitol using chlorobutyl or chlorinated butyl stoppers
TWI498137B (zh) *	2006-06-30	2015-09-01	Abbvie Biotechnology Ltd	自動注射裝置
USD994111S1 (en)	2008-05-12	2023-08-01	Kaleo, Inc.	Medicament delivery device cover
US20100103765A1 (en) *	2008-10-24	2010-04-29	Hornbostel Marc D	Liquid injector for silicon production
CN102596293A (zh) *	2009-09-30	2012-07-18	泰尔茂株式会社	注射辅助器具及药剂注射装置
RU2602039C2 (ru)	2011-01-24	2016-11-10	Эббви Байотекнолоджи Лтд.	Автоматические инъекционные устройства, имеющие наформованные поверхности захвата
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US20160144123A1 (en) *	2014-11-26	2016-05-26	John Berndt	Syringe adapter
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AU2016287571C1 (en)	2015-06-30	2021-12-23	Kaleo, Inc.	Auto-injectors for administration of a medicament within a prefilled syringe
US9579453B1 (en)	2016-02-18	2017-02-28	Chalbourne Brasington	Two-step auto-injection device
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CN119121674A (zh)	2017-03-21	2024-12-13	国际纸业公司	气味控制纸浆组合物
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PT3801694T (pt)	2018-06-08	2025-10-30	Antares Pharma Inc	Injetor de auto-inserção
PT3659594T (pt)	2018-11-30	2020-12-28	Stegemann Klaus	Uma solução estéril com uma seringa de aplicação que contém um agente ativo médico e processo para a sua disponibilização
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US4291695A (en) *	1976-04-05	1981-09-29	Duphar International Research B.V.	Disposable injection syringe
NL180634C (nl) *	1977-12-23	1987-04-01	Duphar Int Res	Injectiespuit alsmede naaldhouder hiervoor.
DE3103897A1 (de) *	1981-02-05	1982-09-09	Kurt Dr. Schreiner	"glasampulle"
US4381779A (en) *	1981-07-16	1983-05-03	Sterling Drug Inc.	Deformable slidable piston to provide self-aspiration in hypodermic cartridge ampoules
ATE15860T1 (de) *	1981-07-27	1985-10-15	Duphar Int Res	Automatische injektionsspritze.
ATE32432T1 (de) *	1981-08-10	1988-02-15	Duphar Int Res	Automatische injektionsspritze.
EP0107874B1 (en) *	1982-10-27	1986-11-26	Duphar International Research B.V	Automatic injection device
DE3673317D1 (de) *	1985-10-11	1990-09-13	Duphar Int Res	Automatische spritze.
US5002935A (en) *	1987-12-30	1991-03-26	University Of Florida	Improvements in redox systems for brain-targeted drug delivery
US4893636A (en) *	1988-03-09	1990-01-16	Sherwood Medical Company	Medical container stopper

1990
- 1990-03-13 DE DE9090200587T patent/DE69000716T2/de not_active Expired - Fee Related
- 1990-03-13 AT AT90200587T patent/ATE84205T1/de not_active IP Right Cessation
- 1990-03-13 DK DK90200587.5T patent/DK0390244T3/da active
- 1990-03-13 ES ES199090200587T patent/ES2036885T3/es not_active Expired - Lifetime
- 1990-03-13 EP EP90200587A patent/EP0390244B1/en not_active Expired - Lifetime
- 1990-03-23 CA CA002012919A patent/CA2012919A1/en not_active Abandoned
- 1990-03-26 JP JP2073578A patent/JPH02283377A/ja active Pending
- 1990-03-26 IL IL9388190A patent/IL93881A/en not_active IP Right Cessation
1992
- 1992-12-14 US US07/990,929 patent/US5383864A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2012919A1 (en)	1990-09-28
US5383864A (en)	1995-01-24
ES2036885T3 (es)	1993-06-01
ATE84205T1 (de)	1993-01-15
EP0390244A1 (en)	1990-10-03
IL93881A0 (en)	1990-12-23
EP0390244B1 (en)	1993-01-07
DK0390244T3 (da)	1993-02-08
DE69000716T2 (de)	1993-07-22
JPH02283377A (ja)	1990-11-20
DE69000716D1 (de)	1993-02-18

Legal Events

Date	Code	Title
1996-06-18	KB	Patent renewed
2000-08-31	KB	Patent renewed
2004-06-01	KB	Patent renewed
2008-04-13	KB	Patent renewed
2011-04-28	EXP	Patent expired

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