IL94422A - Secondary Metabolic Activation Factor Polypeptide (FAS) A gene that encodes for it and a vector that contains that gene - Google Patents

Secondary Metabolic Activation Factor Polypeptide (FAS) A gene that encodes for it and a vector that contains that gene

Info

Publication number: IL94422A
Authority: IL; Israel
Prior art keywords: gene; ala; ser; saf; arg
Prior art date: 1989-05-19

Application number

IL9442290A

Other languages

English (en)

Hebrew (he)

Other versions

IL94422A0 (en

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-05-19

Filing date

1990-05-17

Publication date

1996-10-31

1989-05-19 Priority claimed from US07/354,265 external-priority patent/US5122595A/en

1990-05-17 Application filed by Applied Research Systems filed Critical Applied Research Systems

1990-05-17 Priority to IL11330790A priority Critical patent/IL113307A/en

1991-03-10 Publication of IL94422A0 publication Critical patent/IL94422A0/xx

1996-10-31 Publication of IL94422A publication Critical patent/IL94422A/en

Links

108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 49
229920001184 polypeptide Polymers 0.000 title claims abstract description 48
102000004196 processed proteins & peptides Human genes 0.000 title claims abstract description 48
239000013598 vector Substances 0.000 title claims abstract description 28
230000004913 activation Effects 0.000 title claims abstract description 8
230000024053 secondary metabolic process Effects 0.000 title claims abstract description 8
108090000623 proteins and genes Proteins 0.000 title abstract description 112
239000012634 fragment Substances 0.000 claims abstract description 68
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150000001413 amino acids Chemical class 0.000 claims abstract description 14
238000012258 culturing Methods 0.000 claims abstract description 6
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238000004519 manufacturing process Methods 0.000 claims description 45
239000002773 nucleotide Substances 0.000 claims description 28
125000003729 nucleotide group Chemical group 0.000 claims description 28
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REWSWYIDQIELBE-FXQIFTODSA-N Ala-Val-Ser Chemical compound [H]N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(O)=O REWSWYIDQIELBE-FXQIFTODSA-N 0.000 claims description 4
YYSWCHMLFJLLBJ-ZLUOBGJFSA-N Ala-Ala-Ser Chemical compound C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(O)=O YYSWCHMLFJLLBJ-ZLUOBGJFSA-N 0.000 claims description 3
NCQMBSJGJMYKCK-ZLUOBGJFSA-N Ala-Ser-Ser Chemical compound [H]N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(O)=O NCQMBSJGJMYKCK-ZLUOBGJFSA-N 0.000 claims description 3
GIVATXIGCXFQQA-FXQIFTODSA-N Arg-Ala-Ser Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCCN=C(N)N GIVATXIGCXFQQA-FXQIFTODSA-N 0.000 claims description 3
AAQGRPOPTAUUBM-ZLUOBGJFSA-N Ala-Ala-Asn Chemical compound [H]N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(O)=O AAQGRPOPTAUUBM-ZLUOBGJFSA-N 0.000 claims description 2
OBVSBEYOMDWLRJ-BFHQHQDPSA-N Ala-Gly-Thr Chemical compound C[C@@H](O)[C@@H](C(O)=O)NC(=O)CNC(=O)[C@H](C)N OBVSBEYOMDWLRJ-BFHQHQDPSA-N 0.000 claims description 2
VRTOMXFZHGWHIJ-KZVJFYERSA-N Ala-Thr-Arg Chemical compound [H]N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O VRTOMXFZHGWHIJ-KZVJFYERSA-N 0.000 claims description 2
VHAQSYHSDKERBS-XPUUQOCRSA-N Ala-Val-Gly Chemical compound C[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)NCC(O)=O VHAQSYHSDKERBS-XPUUQOCRSA-N 0.000 claims description 2
KWKQGHSSNHPGOW-BQBZGAKWSA-N Arg-Ala-Gly Chemical compound [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)NCC(O)=O KWKQGHSSNHPGOW-BQBZGAKWSA-N 0.000 claims description 2
KXOPYFNQLVUOAQ-FXQIFTODSA-N Arg-Ser-Ala Chemical compound [H]N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(O)=O KXOPYFNQLVUOAQ-FXQIFTODSA-N 0.000 claims description 2
JJGRJMKUOYXZRA-LPEHRKFASA-N Asn-Arg-Pro Chemical compound C1C[C@@H](N(C1)C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)N)N)C(=O)O JJGRJMKUOYXZRA-LPEHRKFASA-N 0.000 claims description 2
JBRBACJPBZNFMF-YUMQZZPRSA-N Gly-Ala-Lys Chemical compound NCC(=O)N[C@@H](C)C(=O)N[C@H](C(O)=O)CCCCN JBRBACJPBZNFMF-YUMQZZPRSA-N 0.000 claims description 2
RJIVPOXLQFJRTG-LURJTMIESA-N Gly-Arg-Gly Chemical compound OC(=O)CNC(=O)[C@@H](NC(=O)CN)CCCN=C(N)N RJIVPOXLQFJRTG-LURJTMIESA-N 0.000 claims description 2
GGLIDLCEPDHEJO-BQBZGAKWSA-N Gly-Pro-Ala Chemical compound OC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)CN GGLIDLCEPDHEJO-BQBZGAKWSA-N 0.000 claims description 2
SOEGEPHNZOISMT-BYPYZUCNSA-N Gly-Ser-Gly Chemical compound NCC(=O)N[C@@H](CO)C(=O)NCC(O)=O SOEGEPHNZOISMT-BYPYZUCNSA-N 0.000 claims description 2
RMHHNLKYPOOKQN-FXQIFTODSA-N Met-Cys-Ser Chemical compound [H]N[C@@H](CCSC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(O)=O RMHHNLKYPOOKQN-FXQIFTODSA-N 0.000 claims description 2
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SVXXJYJCRNKDDE-AVGNSLFASA-N Pro-Pro-His Chemical compound C([C@@H](C(=O)O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H]1NCCC1)C1=CN=CN1 SVXXJYJCRNKDDE-AVGNSLFASA-N 0.000 claims description 2
BKOKTRCZXRIQPX-ZLUOBGJFSA-N Ser-Ala-Cys Chemical compound C[C@@H](C(=O)N[C@@H](CS)C(=O)O)NC(=O)[C@H](CO)N BKOKTRCZXRIQPX-ZLUOBGJFSA-N 0.000 claims description 2
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UGTZYIPOBYXWRW-SRVKXCTJSA-N Ser-Phe-Asp Chemical compound [H]N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(O)=O)C(O)=O UGTZYIPOBYXWRW-SRVKXCTJSA-N 0.000 claims description 2
VFEHSAJCWWHDBH-RHYQMDGZSA-N Thr-Arg-Leu Chemical compound [H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O VFEHSAJCWWHDBH-RHYQMDGZSA-N 0.000 claims description 2
YZUWGFXVVZQJEI-PMVVWTBXSA-N Thr-Gly-His Chemical compound C[C@H]([C@@H](C(=O)NCC(=O)N[C@@H](CC1=CN=CN1)C(=O)O)N)O YZUWGFXVVZQJEI-PMVVWTBXSA-N 0.000 claims description 2
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Enzymes And Modification Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)

IL9442290A 1989-05-19 1990-05-17 Secondary Metabolic Activation Factor Polypeptide (FAS) A gene that encodes for it and a vector that contains that gene IL94422A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IL11330790A IL113307A (en)	1989-05-19	1990-05-17	Genetic promoter of secondary FAS activation factor (FAS) and expression method to express foreign sequences AND in streptomycin

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/354,265 US5122595A (en)	1989-05-19	1989-05-19	SAF polypeptide gene coding therefor, and SAF promoter
US07/410,706 US5118617A (en)	1989-05-19	1989-09-22	Saf polypeptide, gene coding therefor, saf promoter and expression methods for expressing foreign dna sequences in streptomyces

Publications (2)

Publication Number	Publication Date
IL94422A0 IL94422A0 (en)	1991-03-10
IL94422A true IL94422A (en)	1996-10-31

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ID=26998320

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL9442290A IL94422A (en)	1989-05-19	1990-05-17	Secondary Metabolic Activation Factor Polypeptide (FAS) A gene that encodes for it and a vector that contains that gene
IL11330790A IL113307A (en)	1989-05-19	1990-05-17	Genetic promoter of secondary FAS activation factor (FAS) and expression method to express foreign sequences AND in streptomycin

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL11330790A IL113307A (en)	1989-05-19	1990-05-17	Genetic promoter of secondary FAS activation factor (FAS) and expression method to express foreign sequences AND in streptomycin

Country Status (13)

Country	Link
US (1)	US5118617A (de)
EP (1)	EP0429600B1 (de)
JP (2)	JP2926661B2 (de)
AT (1)	ATE183234T1 (de)
AU (1)	AU638022B2 (de)
CA (1)	CA2033069C (de)
DE (1)	DE69033242T2 (de)
DK (1)	DK0429600T3 (de)
ES (1)	ES2134760T3 (de)
IL (2)	IL94422A (de)
LV (1)	LV10491B (de)
UA (1)	UA27696C2 (de)
WO (1)	WO1990014426A2 (de)

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ZA929284B (en) *	1991-12-12	1993-06-02	Serono Lab	P0438, an new calcium-regulated promoter.
ES2130392T3 (es) *	1992-12-02	1999-07-01	Smithkline Beecham Plc	Procedimiento para la preparacion de acido clavulanico.
US5876987A (en) *	1996-02-07	1999-03-02	Board Of Trustees Operating Michigan State University	Method, DNA and bacteria for hyperproduction of an antibiotic due to disruption of an AbsA gene
WO1998050557A1 (en) *	1997-05-02	1998-11-12	University Of Guelph	Proteins involved in the synthesis and assembly of core lipopolysaccharide of pseudomonas aeruginosa
AU2577799A (en) *	1998-02-09	1999-08-23	Human Genome Sciences, Inc.	45 human secreted proteins
US6197591B1 (en)	1998-09-14	2001-03-06	Pfizer Inc.	Streptomyces avermitilis regulatory genes for increased avermectin production
US8410248B2 (en) *	1999-03-12	2013-04-02	Human Genome Sciences Inc.	HWBAO62 polypeptides
DE10131441A1 (de) *	2001-06-29	2003-01-30	Henkel Kgaa	Eine neue Gruppe von alpha-Amylasen sowie ein Verfahren zur Identifizierung und Gewinnung neuer alpha-Amylasen
WO2020118043A1 (en) *	2018-12-07	2020-06-11	Coherus Biosciences, Inc.	Methods for producing recombinant proteins

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4745056A (en) *	1984-10-23	1988-05-17	Biotechnica International, Inc.	Streptomyces secretion vector

1989
- 1989-09-22 US US07/410,706 patent/US5118617A/en not_active Expired - Lifetime
1990
- 1990-05-17 IL IL9442290A patent/IL94422A/en not_active IP Right Cessation
- 1990-05-17 IL IL11330790A patent/IL113307A/en not_active IP Right Cessation
- 1990-05-18 DK DK90908581T patent/DK0429600T3/da active
- 1990-05-18 EP EP90908581A patent/EP0429600B1/de not_active Expired - Lifetime
- 1990-05-18 DE DE69033242T patent/DE69033242T2/de not_active Expired - Fee Related
- 1990-05-18 CA CA002033069A patent/CA2033069C/en not_active Expired - Lifetime
- 1990-05-18 UA UA4894397A patent/UA27696C2/uk unknown
- 1990-05-18 AU AU57217/90A patent/AU638022B2/en not_active Ceased
- 1990-05-18 JP JP2507993A patent/JP2926661B2/ja not_active Expired - Fee Related
- 1990-05-18 ES ES90908581T patent/ES2134760T3/es not_active Expired - Lifetime
- 1990-05-18 WO PCT/GB1990/000781 patent/WO1990014426A2/en not_active Ceased
- 1990-05-18 AT AT90908581T patent/ATE183234T1/de not_active IP Right Cessation
1993
- 1993-03-12 LV LVP-93-184A patent/LV10491B/en unknown
1998
- 1998-12-16 JP JP10357972A patent/JP3131192B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
LV10491A (lv)	1995-02-20
EP0429600A1 (de)	1991-06-05
AU638022B2 (en)	1993-06-17
CA2033069A1 (en)	1990-11-20
JPH04501855A (ja)	1992-04-02
WO1990014426A2 (en)	1990-11-29
IL94422A0 (en)	1991-03-10
DE69033242D1 (de)	1999-09-16
IL113307A0 (en)	1995-07-31
LV10491B (en)	1995-10-20
EP0429600B1 (de)	1999-08-11
AU5721790A (en)	1990-12-18
UA27696C2 (uk)	2000-10-16
JP3131192B2 (ja)	2001-01-31
DK0429600T3 (da)	1999-12-06
JP2926661B2 (ja)	1999-07-28
CA2033069C (en)	2000-07-11
US5118617A (en)	1992-06-02
IL113307A (en)	1996-10-31
WO1990014426A3 (en)	1991-01-24
ES2134760T3 (es)	1999-10-16
JPH11235190A (ja)	1999-08-31
ATE183234T1 (de)	1999-08-15
DE69033242T2 (de)	1999-12-02

Legal Events

Date	Code	Title
1997-03-18	FF	Patent granted
1997-07-13	KB	Patent renewed
2000-07-16	HE	Change of address of proprietor(s)
2000-08-31	KB	Patent renewed
2004-07-25	KB	Patent renewed
2008-07-09	KB	Patent renewed
2011-04-28	EXP	Patent expired

Publication	Publication Date	Title
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RU2124559C1 (ru)	1999-01-10	РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК, СПОСОБ ЭКСПРЕССИИ В КЛЕТКАХ STREPTOMYCES ГЕНА α -АМИЛАЗЫ
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US20040086962A1 (en)	2004-05-06	Methods and materials relating to gene expression
AU647471B2 (en)	1994-03-24	Heterologous promoter systems
KR19990074514A (ko)	1999-10-05	아미노글라이코사이드계 항생제에 대해 다제내성을지정하는유전자
JPH0724585B2 (ja)	1995-03-22	放線菌プロモーターｄｎａ配列
WO1997011187A1 (en)	1997-03-27	Subtilisin inhibitor of streptomyces venezuelae, and use of the gene sequences for expression and/or secretion of heterologous proteins in streptomyces