IL96367A - 5,11-dihydro-6H-dipyrido [3,2-b:2', 3'-e][1,4] diazepine-6-(thi)ones their preparation and pharmaceutical compositions containing them - Google Patents

5,11-dihydro-6H-dipyrido [3,2-b:2', 3'-e][1,4] diazepine-6-(thi)ones their preparation and pharmaceutical compositions containing them

Info

Publication number
IL96367A
IL96367A IL9636790A IL9636790A IL96367A IL 96367 A IL96367 A IL 96367A IL 9636790 A IL9636790 A IL 9636790A IL 9636790 A IL9636790 A IL 9636790A IL 96367 A IL96367 A IL 96367A
Authority
IL
Israel
Prior art keywords
dipyrido
diazepine
thi
dihydro
ones
Prior art date
Application number
IL9636790A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Pharma
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27412005&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL96367(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from IL9488390A external-priority patent/IL94883A/en
Application filed by Boehringer Ingelheim Pharma, Thomae Gmbh Dr K filed Critical Boehringer Ingelheim Pharma
Publication of IL96367A publication Critical patent/IL96367A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL9636790A 1989-11-17 1990-11-16 5,11-dihydro-6H-dipyrido [3,2-b:2', 3'-e][1,4] diazepine-6-(thi)ones their preparation and pharmaceutical compositions containing them IL96367A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US43892389A 1989-11-17 1989-11-17
IL9488390A IL94883A (en) 1989-06-28 1990-06-27 5, 11-Dihydro-6h-dipyrido [3,2-b: 2',3'-e] [1,4] diazepin-6-ones and- thiones, their preparation and pharmaceutical compositions containing them
US57900190A 1990-09-06 1990-09-06
US60039090A 1990-10-19 1990-10-19

Publications (1)

Publication Number Publication Date
IL96367A true IL96367A (en) 1997-02-18

Family

ID=27412005

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9636790A IL96367A (en) 1989-11-17 1990-11-16 5,11-dihydro-6H-dipyrido [3,2-b:2', 3'-e][1,4] diazepine-6-(thi)ones their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
EP (1) EP0429987B1 (fr)
AP (1) AP179A (fr)
AT (1) ATE177744T1 (fr)
AU (1) AU630251B2 (fr)
CA (1) CA2030056C (fr)
DE (2) DE69033003T2 (fr)
DK (1) DK0429987T3 (fr)
ES (1) ES2130114T3 (fr)
FI (1) FI94529C (fr)
GR (1) GR3030100T3 (fr)
IE (1) IE904141A1 (fr)
IL (1) IL96367A (fr)
LU (1) LU90393I2 (fr)
NL (1) NL990022I2 (fr)
NO (2) NO175478C (fr)
NZ (1) NZ236105A (fr)
OA (1) OA09852A (fr)
PT (1) PT95919B (fr)
RU (1) RU2040527C1 (fr)
UA (1) UA34420C2 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366972A (en) * 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
GB9109557D0 (en) * 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
US5200522A (en) * 1991-06-11 1993-04-06 Boehringer Ingelheim Pharmaceuticals, Inc. Method for preparing 3-amino-2-chloro-4-alkylpyridines
WO1992022531A1 (fr) * 1991-06-11 1992-12-23 Boehringer Ingelheim Pharmaceuticals, Inc. Procede de preparation de 3-amino-2-chloro-4-alkylpyridines
DE4138908A1 (de) * 1991-11-27 1993-06-03 Bayer Ag 6-thiono-dibenz(b,e)azepine
DE4138853A1 (de) * 1991-11-27 1993-06-03 Bayer Ag 5,6-dihydro-dibenz(b,e)azepin-6,11-dion-11- oxime
DK0598396T3 (da) * 1992-11-18 1998-11-23 Boehringer Ingelheim Pharma Forbedret fremgangsmåde til fremstilling af 3-amino-2-chlor-4-alkylpyridiner
WO1994017075A1 (fr) * 1993-01-20 1994-08-04 A. Menarini Industrie Farmaceutiche Riunite S.R.L. Derives de diazepine et compositions antivirales
DE4333697A1 (de) * 1993-10-02 1995-04-06 Merck Patent Gmbh Verfahren zur Herstellung von 3-Aminopyridinen aus 3-Nitropyridinen
DE4403311C1 (de) * 1994-02-03 1995-04-20 Boehringer Ingelheim Kg Verfahren zur Herstellung von Nevirapine (11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4-diazepin]-6-on)
AU690646B2 (en) * 1994-02-18 1998-04-30 Boehringer Ingelheim Pharmaceuticals, Inc. 2-heteroaryl-5,11-dihydro-6H-dipyrido(3,2-b:2',3'-e)(1 ,4)diazepines and their use in the prevention or treatment of HIV infection
DE69525978T2 (de) * 1995-06-06 2002-12-19 Pfizer Trizyclische 5,6-dihydro-9h-pyrazolo(3,4-c)-1,2,4-triazolo(4,3-alpha)pyridine
US5917033A (en) * 1995-10-31 1999-06-29 University Of Medicine & Dentistry Of New Jersey Structure based design of inhibitors of HIV-1 reverse transcriptase
US5747488A (en) * 1996-01-30 1998-05-05 Boehringer Ingelheim Pharmaceuticals, Inc. 2-aryl-5,11-dihydro-6H-dipyrido 3,2-B:2',3'-E! 1, 4!diazepines and their use in the treatment of HIV infection
PT1019058E (pt) * 1997-08-25 2006-08-31 Boehringer Ingelheim Pharma Suspensao farmaceutica contendo hemi-hidrato de nevirapina.
DE10023492A1 (de) * 2000-05-09 2001-11-22 Schering Ag Aza- und Polyazanthranylamide und deren Verwendung als Arzneimittel
US7105682B2 (en) 2001-01-12 2006-09-12 Amgen Inc. Substituted amine derivatives and methods of use
US6878714B2 (en) 2001-01-12 2005-04-12 Amgen Inc. Substituted alkylamine derivatives and methods of use
US7102009B2 (en) 2001-01-12 2006-09-05 Amgen Inc. Substituted amine derivatives and methods of use
US6995162B2 (en) 2001-01-12 2006-02-07 Amgen Inc. Substituted alkylamine derivatives and methods of use
US7307088B2 (en) 2002-07-09 2007-12-11 Amgen Inc. Substituted anthranilic amide derivatives and methods of use
KR20070033032A (ko) 2004-07-16 2007-03-23 프로테오시스 악티엔게젤샤프트 세포보호제로서 ｐａｒｐ 및 ｓｉｒ 조절 활성을 갖는무스카린 길항제
US8247556B2 (en) 2005-10-21 2012-08-21 Amgen Inc. Method for preparing 6-substituted-7-aza-indoles
WO2008154234A2 (fr) 2007-06-08 2008-12-18 Boehringer Ingelheim International Gmbh Formulation à libération prolongée de névirapine
US20110294791A1 (en) 2009-01-13 2011-12-01 Proteosys Ag Pirenzepine as an agent in cancer treatment
CA2968464A1 (fr) 2014-11-25 2016-06-02 Bayer Pharma Aktiengesellschaft Derives de pyridobenzodiazepinone substitues et leur utilisation
EP3153157A1 (fr) 2015-10-09 2017-04-12 Teva Pharmaceutical Works Private Limited Company Composition pharmaceutique à libération prolongée de névirapine
CN107382848A (zh) * 2017-07-15 2017-11-24 河北蓝泰化工科技有限公司 一种烟酰胺化合物及其制备方法和应用
CN116606243A (zh) * 2023-05-19 2023-08-18 中科苏州药物研究院 一种安全高效合成奈伟拉平中间体的新工艺

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA783570A (en) * 1968-04-23 Schmidt Gunther 5,6-dihydro-6-oxo-11h-pyrido (2,3-b) (1,4)-benzodiazepines
CA658624A (en) * 1963-02-26 Schmutz Jean Diazepine derivatives
CA554134A (fr) * 1958-03-11 Hoffmann Karl Composes thia-aza-cycloheptadiene et procede pour leur fabrication
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3726908A1 (de) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3735895A1 (de) * 1987-10-23 1989-05-03 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE69002079T2 (de) * 1989-04-20 1993-11-18 Boehringer Ingelheim Pharma 5,11-Dihydro-6H-dipyrido [3,2-b:2',3'-e]diazepin-6-one und deren Verwendung in der Vorbeugung und Behandlung von AIDS.
DE69031845T2 (de) * 1989-04-20 1998-05-07 Boehringer Ingelheim Pharma 6,11-Dihydro-5H-pyrido(2,3-b)(1,5)benzodiazepin-5-one und Thione und ihre Verwendung für die Vorbeugung oder Behandlung von AIDS
ATE103918T1 (de) * 1989-06-28 1994-04-15 Boehringer Ingelheim Pharma 5,11-dihydro-6h-dipyrido(3,2-b:2',3'e>(1,4>diazepin-6-one und -thione und ihre verwendung bei der aids-vorbeugung oder behandlung.

Also Published As

Publication number Publication date
NL990022I2 (nl) 2007-11-01
ES2130114T3 (es) 1999-07-01
OA09852A (en) 1994-08-15
DK0429987T3 (da) 1999-10-11
ATE177744T1 (de) 1999-04-15
GR3030100T3 (en) 1999-07-30
IE904141A1 (en) 1991-05-22
DE69033003D1 (de) 1999-04-22
AU6673290A (en) 1991-05-23
EP0429987B1 (fr) 1999-03-17
NO904986D0 (no) 1990-11-16
FI905674A7 (fi) 1991-05-18
LU90393I2 (fr) 1999-06-30
CA2030056A1 (fr) 1991-05-18
UA34420C2 (uk) 2001-03-15
NO175478B (no) 1994-07-11
HK1011025A1 (en) 1999-07-02
DE69033003T2 (de) 1999-09-16
NL990022I1 (nl) 1999-10-01
NO1999013I1 (no) 1999-06-29
AP179A (en) 1992-04-30
AU630251B2 (en) 1992-10-22
FI94529B (fi) 1995-06-15
PT95919B (pt) 1998-01-30
NO904986L (no) 1991-05-21
RU2040527C1 (ru) 1995-07-25
NO175478C (no) 1994-10-19
PT95919A (pt) 1991-09-13
AP9000224A0 (en) 1991-01-31
FI905674A0 (fi) 1990-11-16
FI94529C (fi) 1995-09-25
CA2030056C (fr) 1995-10-17
EP0429987A2 (fr) 1991-06-05
NZ236105A (en) 1994-04-27
EP0429987A3 (en) 1992-01-22
DE19975051I2 (de) 2004-05-06

Similar Documents

Publication Publication Date Title
IL96367A (en) 5,11-dihydro-6H-dipyrido [3,2-b:2', 3'-e][1,4] diazepine-6-(thi)ones their preparation and pharmaceutical compositions containing them
IL94883A0 (en) 5,11-dihydro-6h-dihydro(3,2-b:2',3'-e)(1,4)diazepin-6-ones and-thiones,their preparation and pharmaceutical compositions containing them
IL95155A0 (en) 1h-indazole-3-carboxamides,their preparation and pharmaceutical compositions containing them
IL95640A0 (en) 1-cycloalkylpiperidines,their preparation and pharmaceutical compositions containing them
IL96577A0 (en) Heterocyclic substituted acylaminothiazoles,their preparation and pharmaceutical compositions containing them
EP0412350A3 (en) Renininhibitors, procedure for their preparation and use as medicaments
IL95045A0 (en) Thienodiazepine derivatives,their preparation and pharmaceutical compositions containing them
IL89347A0 (en) Thieno(3,2-b)pyridines,process for their preparation and pharmaceutical compositions containing them
IL94556A0 (en) Hydroxypropylamines,their preparation and pharmaceutical compositions containing them
IL95622A0 (en) Condensed diazepinones,their preparation and pharmaceutical compositions containing them
IL81209A (en) Substituted 6h-indolo(2,3-b)-quinoxalines,their preparation and pharmaceutical compositions comprising them
IL93136A0 (en) Tetrahydroimidazo(1,4)benzodiazepin-2-thione derivatives,their preparation and pharmaceutical compositions containing them
IL93124A0 (en) Benzocycloalkenyldihydroxyalkanoic-acid derivatives,their preparation and pharmaceutical compositions
IL96384A0 (en) Pyridazine derivatives,their preparation and pharmaceutical compositions containing them
IL94763A0 (en) R(-)3-quinuclidinol derivatives,their preparation and pharmaceutical compositions containing them
IL96589A0 (en) 2-substituted-imidazo-(4,5-c)pyridines,their preparation,and pharmaceutical compositions containing them
IL90590A0 (en) Condensed diazepinones,their preparation and pharmaceutical compositions containing them
IL93750A0 (en) Tetrahydronaphthalene derivatives,their preparation and pharmaceutical compositions containing them
IL91737A0 (en) 2,7-diamino-1,2,3,4-tetrahydro-naphthalenes,their preparation and pharmaceutical compositions containing them
IL95621A0 (en) Condensed diazepinones,their preparation and pharmaceutical compositions containing them
IL95563A0 (en) Substituted amino-pyridines,their preparation and pharmaceutical compositions containing them
IL93613A0 (en) Azole-1-alkanamides,their preparation and pharmaceutical compositions comprising them
IL95638A0 (en) Tetrahydroimidazo(1,4)benzodiazepines,their preparation and pharmaceutical compositions containing them
IL95142A0 (en) 2-amino-7-carbamoyl-1,2,3,4-tetrahydronaphthalenes,their preparation and pharmaceutical compositions containing them
IL89098A0 (en) Condensed diazepinones,their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed