LU90393I2 - Nevirapine"11-cyclopropyl-5.11-dihydro-4-methyl-6h-diphridol(3,2-b:2'.3'-e)(1,4)diazepin-6-one ou l'un des ses sels d'addition d'acide pharmaceutiquement acceptable - Google Patents

Nevirapine"11-cyclopropyl-5.11-dihydro-4-methyl-6h-diphridol(3,2-b:2'.3'-e)(1,4)diazepin-6-one ou l'un des ses sels d'addition d'acide pharmaceutiquement acceptable

Info

Publication number
LU90393I2
LU90393I2 LU90393C LU90393C LU90393I2 LU 90393 I2 LU90393 I2 LU 90393I2 LU 90393 C LU90393 C LU 90393C LU 90393 C LU90393 C LU 90393C LU 90393 I2 LU90393 I2 LU 90393I2
Authority
LU
Luxembourg
Prior art keywords
diphridol
diazepin
nevirapine
cyclopropyl
dihydro
Prior art date
Application number
LU90393C
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27412005&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU90393(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of LU90393I2 publication Critical patent/LU90393I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
LU90393C 1989-11-17 1999-04-30 Nevirapine"11-cyclopropyl-5.11-dihydro-4-methyl-6h-diphridol(3,2-b:2'.3'-e)(1,4)diazepin-6-one ou l'un des ses sels d'addition d'acide pharmaceutiquement acceptable LU90393I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43892389A 1989-11-17 1989-11-17
US57900190A 1990-09-06 1990-09-06
US60039090A 1990-10-19 1990-10-19

Publications (1)

Publication Number Publication Date
LU90393I2 true LU90393I2 (fr) 1999-06-30

Family

ID=27412005

Family Applications (1)

Application Number Title Priority Date Filing Date
LU90393C LU90393I2 (fr) 1989-11-17 1999-04-30 Nevirapine"11-cyclopropyl-5.11-dihydro-4-methyl-6h-diphridol(3,2-b:2'.3'-e)(1,4)diazepin-6-one ou l'un des ses sels d'addition d'acide pharmaceutiquement acceptable

Country Status (20)

Country Link
EP (1) EP0429987B1 (fr)
AP (1) AP179A (fr)
AT (1) ATE177744T1 (fr)
AU (1) AU630251B2 (fr)
CA (1) CA2030056C (fr)
DE (2) DE19975051I2 (fr)
DK (1) DK0429987T3 (fr)
ES (1) ES2130114T3 (fr)
FI (1) FI94529C (fr)
GR (1) GR3030100T3 (fr)
IE (1) IE904141A1 (fr)
IL (1) IL96367A (fr)
LU (1) LU90393I2 (fr)
NL (1) NL990022I2 (fr)
NO (2) NO175478C (fr)
NZ (1) NZ236105A (fr)
OA (1) OA09852A (fr)
PT (1) PT95919B (fr)
RU (1) RU2040527C1 (fr)
UA (1) UA34420C2 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366972A (en) * 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
GB9109557D0 (en) * 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
JP3133331B2 (ja) * 1991-06-11 2001-02-05 ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド ３―アミノ―２―クロロ―４―アルキルピリジン類の製造方法
US5200522A (en) * 1991-06-11 1993-04-06 Boehringer Ingelheim Pharmaceuticals, Inc. Method for preparing 3-amino-2-chloro-4-alkylpyridines
DE4138908A1 (de) * 1991-11-27 1993-06-03 Bayer Ag 6-thiono-dibenz(b,e)azepine
DE4138853A1 (de) * 1991-11-27 1993-06-03 Bayer Ag 5,6-dihydro-dibenz(b,e)azepin-6,11-dion-11- oxime
DK0598396T3 (da) * 1992-11-18 1998-11-23 Boehringer Ingelheim Pharma Forbedret fremgangsmåde til fremstilling af 3-amino-2-chlor-4-alkylpyridiner
WO1994017075A1 (fr) * 1993-01-20 1994-08-04 A. Menarini Industrie Farmaceutiche Riunite S.R.L. Derives de diazepine et compositions antivirales
DE4333697A1 (de) * 1993-10-02 1995-04-06 Merck Patent Gmbh Verfahren zur Herstellung von 3-Aminopyridinen aus 3-Nitropyridinen
DE4403311C1 (de) * 1994-02-03 1995-04-20 Boehringer Ingelheim Kg Verfahren zur Herstellung von Nevirapine (11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4-diazepin]-6-on)
PL181323B1 (pl) * 1994-02-18 2001-07-31 Boehringer Ingelheim Pharma 2-heteroarylo-5,11-dihydro-6H-dipirydo[3,2-b:2’,3'-e][1,4] diazepinyi ich zastosowanie w zapobieganiu i leczeniu zakazen HIV PL PL PL
DE69525978T2 (de) * 1995-06-06 2002-12-19 Pfizer Trizyclische 5,6-dihydro-9h-pyrazolo(3,4-c)-1,2,4-triazolo(4,3-alpha)pyridine
US5917033A (en) * 1995-10-31 1999-06-29 University Of Medicine & Dentistry Of New Jersey Structure based design of inhibitors of HIV-1 reverse transcriptase
US5747488A (en) * 1996-01-30 1998-05-05 Boehringer Ingelheim Pharmaceuticals, Inc. 2-aryl-5,11-dihydro-6H-dipyrido 3,2-B:2',3'-E! 1, 4!diazepines and their use in the treatment of HIV infection
IL134185A (en) * 1997-08-25 2005-11-20 Boehringer Ingelheim Pharma Preparation of nevirapine hemihydrate and pharmaceutical suspensions containing it
DE10023492A1 (de) * 2000-05-09 2001-11-22 Schering Ag Aza- und Polyazanthranylamide und deren Verwendung als Arzneimittel
US6878714B2 (en) 2001-01-12 2005-04-12 Amgen Inc. Substituted alkylamine derivatives and methods of use
US7102009B2 (en) 2001-01-12 2006-09-05 Amgen Inc. Substituted amine derivatives and methods of use
US7105682B2 (en) 2001-01-12 2006-09-12 Amgen Inc. Substituted amine derivatives and methods of use
US6995162B2 (en) 2001-01-12 2006-02-07 Amgen Inc. Substituted alkylamine derivatives and methods of use
US7307088B2 (en) 2002-07-09 2007-12-11 Amgen Inc. Substituted anthranilic amide derivatives and methods of use
WO2006008119A1 (fr) 2004-07-16 2006-01-26 Proteosys Ag Antagonistes muscariniques avec activite modulatrice parp et sin en tant qu'agents contre les maladies inflammatoires
US8247556B2 (en) 2005-10-21 2012-08-21 Amgen Inc. Method for preparing 6-substituted-7-aza-indoles
DK2155169T3 (en) 2007-06-08 2016-06-13 Boehringer Ingelheim Int Formulation of nevirapine extended release
EP2387405A2 (fr) 2009-01-13 2011-11-23 ProteoSys AG Pirenzépine en tant qu'agent utilisé dans le traitement du cancer
JP2017535573A (ja) 2014-11-25 2017-11-30 バイエル ファーマ アクチエンゲゼルシャフト 置換されたピリドベンゾジアゼピノン誘導体およびそれの使用
EP3153157A1 (fr) 2015-10-09 2017-04-12 Teva Pharmaceutical Works Private Limited Company Composition pharmaceutique à libération prolongée de névirapine
CN107382848A (zh) * 2017-07-15 2017-11-24 河北蓝泰化工科技有限公司 一种烟酰胺化合物及其制备方法和应用
CN116606243A (zh) * 2023-05-19 2023-08-18 中科苏州药物研究院 一种安全高效合成奈伟拉平中间体的新工艺

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA658624A (en) * 1963-02-26 Schmutz Jean Diazepine derivatives
CA554134A (fr) * 1958-03-11 Hoffmann Karl Composes thia-aza-cycloheptadiene et procede pour leur fabrication
CA783570A (en) * 1968-04-23 Schmidt Gunther 5,6-dihydro-6-oxo-11h-pyrido (2,3-b) (1,4)-benzodiazepines
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3726908A1 (de) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3735895A1 (de) * 1987-10-23 1989-05-03 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE69031845T2 (de) * 1989-04-20 1998-05-07 Boehringer Ingelheim Pharma 6,11-Dihydro-5H-pyrido(2,3-b)(1,5)benzodiazepin-5-one und Thione und ihre Verwendung für die Vorbeugung oder Behandlung von AIDS
ES2058656T3 (es) * 1989-04-20 1994-11-01 Boehringer Ingelheim Pharma 5,11-dihidro-6h-dipirido(3,2-b:2',3'-e)(1,4)diazepin-6-onas y su uso en la prevencion o tratamiento del sida.
ES2063202T3 (es) * 1989-06-28 1995-01-01 Boehringer Ingelheim Pharma Nuevas 5,11-dihidro-6h-dipirido(3,2-b:2',3'-e)(1,4)diazepin-6-onas y -tionas y su uso en la prevencion o tratamiento del sida.

Also Published As

Publication number Publication date
AP9000224A0 (en) 1991-01-31
DK0429987T3 (da) 1999-10-11
UA34420C2 (uk) 2001-03-15
IL96367A (en) 1997-02-18
HK1011025A1 (en) 1999-07-02
DE69033003D1 (de) 1999-04-22
NO1999013I1 (no) 1999-06-29
NZ236105A (en) 1994-04-27
RU2040527C1 (ru) 1995-07-25
ATE177744T1 (de) 1999-04-15
NO904986D0 (no) 1990-11-16
CA2030056A1 (fr) 1991-05-18
EP0429987A2 (fr) 1991-06-05
DE19975051I2 (de) 2004-05-06
AU630251B2 (en) 1992-10-22
FI94529C (fi) 1995-09-25
PT95919A (pt) 1991-09-13
NO904986L (no) 1991-05-21
FI94529B (fi) 1995-06-15
NO175478C (no) 1994-10-19
CA2030056C (fr) 1995-10-17
GR3030100T3 (en) 1999-07-30
FI905674A0 (fi) 1990-11-16
OA09852A (en) 1994-08-15
AP179A (en) 1992-04-30
AU6673290A (en) 1991-05-23
ES2130114T3 (es) 1999-07-01
NL990022I2 (nl) 2007-11-01
DE69033003T2 (de) 1999-09-16
IE904141A1 (en) 1991-05-22
PT95919B (pt) 1998-01-30
NO175478B (no) 1994-07-11
EP0429987B1 (fr) 1999-03-17
NL990022I1 (nl) 1999-10-01
EP0429987A3 (en) 1992-01-22
FI905674A7 (fi) 1991-05-18

Similar Documents

Publication Publication Date Title
PT86726A (pt) Procede de preparation de l:enantiomere dextrogyre de l:alpha-(tetrahydro-4,5,6,7-thieno(3,2-c)pyridyl-5) (chloro-2-phenyl)-acetate de methyle
FI905674A0 (fi) Menetelmä valmistaa farmaseuttisesti käyttökelpoisia 5,11-dihydro-6H-dipyrido/3,2-b:2',3'-e//1,4/diatsepin-6-oneja ja -tioneja
NO1997005I1 (no) Olanzapin
FI92828C (fi) Menetelmä valmistaa terapeuttisesti arvokasta 5,11-dihydro-6H-dipyrido/3,2-b:2',3'-e/ /1,4/diatsepin-6-onia
DE3888897D1 (de) Imidazo[1,2-b]pyridazinderivate.
NO903591D0 (no) Fremgangsmaate for fremstilling av pyrido(3,4-b)(1,4)benzoksazepiner samt anvendelse som medikamenter.
FI914923A0 (fi) Foerfarande foer framstaellning av 5,11 -dihydro-6h-dipyrido-/3,2-b:2',3'-e//1,4/diazepiner. knippe.
NO166366C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive cycloalkan (1,2-c:4,3-c')dipyrazoler.
ITMI911577A1 (it) Procedimento per la preparazione dell'acido 9-fluoro-10- (4-metil-1-piperazinil)-7-oxo-2, 3-diidro-7h-pirido (1, 2, 3-de) (1, 4)benzotiadin-6-carbossilico cloridrato.
FR2619112B1 (fr) Derives de (piperidinyl-4)methyl-2 benzo(b)furo(2,3-c) pyridines, leur preparation et leur application en therapeutique
ES2023410B3 (es) Acidos 1,3,4,9-tetrahidropiran 3,4-b]indol -1 aceticos sustituidos.
NO167511C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte tieno(3,4-d)imidazolderivater.
DK530388D0 (da) Pyrrolo-(1,2-b)cinnoliner og farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse
NO882794D0 (no) Fremgangsmaate for fremstilling av kalsium-10-propyl-2,8-bis(1h-tetrazol-5-yl)-4h,6h-benzo(1,2-b; 5,4-b')dipyran-4,6-dion.
ITMI910388A0 (it) Procedimento per la preparazione dell'1,3a,8,-trimetil-1,2,3,3a,8,-8a-esaidro pirrol (2,3-b) indolo-5(3as,8ar)-eptilcarbammato
NO903778D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive pyrido(2,3-b) benzazepin- (og -tiazepin) 5(6h)-on-derivater.
FR2699921B1 (fr) Dérivés d'acide 2-(thien-2-yl)imidazo[2,1-b]benzothiazole-3-acétique, leur préparation et leur application en thérapeutique.
GB2009157A (en) Salts of 2,8-Dicarboxy-4,6- Dioxo-10-propyl-4H,6H-Benzo [1,2- b:5,4-b']pyran
PT82243A (fr) Procede de preparation de nouvelles 5-h pyrido<3',4':4,5>pyrrolo<3,2-c>pyridines
AU646096C (en) Method for the preparation of 5,11-dihydro-6H-dipyrido (3,2-b:2',3'-e)(1,4)diazepines
FR2646850B1 (fr) Derives d'acide dibenzo(b,e)thiepinne-3-acetique, leur preparation et leur application en therapeutique
ES1010646Y (es) Juego de golf infantil.
LV5737B4 (lv) Tetrahidro-1H-pirido[4,3-B]indol-1-ona atvasinajumi
ES1003557Y (es) Nuevo juego infantil.
ES1003558Y (es) Nuevo juego infantil.