LU90393I2 - Nevirapine"11-cyclopropyl-5.11-dihydro-4-methyl-6h-diphridol(3,2-b:2'.3'-e)(1,4)diazepin-6-one ou l'un des ses sels d'addition d'acide pharmaceutiquement acceptable - Google Patents

Nevirapine"11-cyclopropyl-5.11-dihydro-4-methyl-6h-diphridol(3,2-b:2'.3'-e)(1,4)diazepin-6-one ou l'un des ses sels d'addition d'acide pharmaceutiquement acceptable

Info

Publication number: LU90393I2
Authority: LU; Luxembourg
Prior art keywords: diphridol; diazepin; nevirapine; cyclopropyl; dihydro
Prior art date: 1989-11-17

Application number

LU90393C

Other languages

English (en)

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-17

Filing date

1999-04-30

Publication date

1999-06-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27412005&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU90393(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-04-30 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

1999-06-30 Publication of LU90393I2 publication Critical patent/LU90393I2/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

LU90393C 1989-11-17 1999-04-30 Nevirapine"11-cyclopropyl-5.11-dihydro-4-methyl-6h-diphridol(3,2-b:2'.3'-e)(1,4)diazepin-6-one ou l'un des ses sels d'addition d'acide pharmaceutiquement acceptable LU90393I2 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US43892389A	1989-11-17	1989-11-17
US57900190A	1990-09-06	1990-09-06
US60039090A	1990-10-19	1990-10-19

Publications (1)

Publication Number	Publication Date
LU90393I2 true LU90393I2 (fr)	1999-06-30

Family

ID=27412005

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
LU90393C LU90393I2 (fr)	1989-11-17	1999-04-30	Nevirapine"11-cyclopropyl-5.11-dihydro-4-methyl-6h-diphridol(3,2-b:2'.3'-e)(1,4)diazepin-6-one ou l'un des ses sels d'addition d'acide pharmaceutiquement acceptable

Country Status (20)

Country	Link
EP (1)	EP0429987B1 (fr)
AP (1)	AP179A (fr)
AT (1)	ATE177744T1 (fr)
AU (1)	AU630251B2 (fr)
CA (1)	CA2030056C (fr)
DE (2)	DE69033003T2 (fr)
DK (1)	DK0429987T3 (fr)
ES (1)	ES2130114T3 (fr)
FI (1)	FI94529C (fr)
GR (1)	GR3030100T3 (fr)
IE (1)	IE904141A1 (fr)
IL (1)	IL96367A (fr)
LU (1)	LU90393I2 (fr)
NL (1)	NL990022I2 (fr)
NO (2)	NO175478C (fr)
NZ (1)	NZ236105A (fr)
OA (1)	OA09852A (fr)
PT (1)	PT95919B (fr)
RU (1)	RU2040527C1 (fr)
UA (1)	UA34420C2 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5366972A (en) *	1989-04-20	1994-11-22	Boehringer Ingelheim Pharmaceuticals, Inc.	5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
GB9109557D0 (en) *	1991-05-02	1991-06-26	Wellcome Found	Chemical compounds
US5200522A (en) *	1991-06-11	1993-04-06	Boehringer Ingelheim Pharmaceuticals, Inc.	Method for preparing 3-amino-2-chloro-4-alkylpyridines
WO1992022531A1 (fr) *	1991-06-11	1992-12-23	Boehringer Ingelheim Pharmaceuticals, Inc.	Procede de preparation de 3-amino-2-chloro-4-alkylpyridines
DE4138908A1 (de) *	1991-11-27	1993-06-03	Bayer Ag	6-thiono-dibenz(b,e)azepine
DE4138853A1 (de) *	1991-11-27	1993-06-03	Bayer Ag	5,6-dihydro-dibenz(b,e)azepin-6,11-dion-11- oxime
ES2121916T3 (es) *	1992-11-18	1998-12-16	Boehringer Ingelheim Pharma	Metodo mejorado para la preparacion de 3-amino-2-cloro-4-alquilpiridinas.
AU5883794A (en) *	1993-01-20	1994-08-15	A. Menarini Industrie Farmaceutiche Riunite S.R.L.	Diazepin derivatives and antiviral compositions
DE4333697A1 (de) *	1993-10-02	1995-04-06	Merck Patent Gmbh	Verfahren zur Herstellung von 3-Aminopyridinen aus 3-Nitropyridinen
DE4403311C1 (de) *	1994-02-03	1995-04-20	Boehringer Ingelheim Kg	Verfahren zur Herstellung von Nevirapine (11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4-diazepin]-6-on)
CO4340691A1 (es) *	1994-02-18	1996-07-30	Boehringer Ingelheim Pharma	2-HETEROARIL-5,11-DIHIDRO-6H-DIPIRIDO(3,2-b:2´, 3´ -e) (1, 4)-DIAZEPINAS .
ES2172583T3 (es) *	1995-06-06	2002-10-01	Pfizer	5,6-dihidro-9h-pirazol(3,4-c)-1,2,4-triazol(4,3-alfa)piridinas triciclicas.
US5917033A (en) *	1995-10-31	1999-06-29	University Of Medicine & Dentistry Of New Jersey	Structure based design of inhibitors of HIV-1 reverse transcriptase
US5747488A (en) *	1996-01-30	1998-05-05	Boehringer Ingelheim Pharmaceuticals, Inc.	2-aryl-5,11-dihydro-6H-dipyrido 3,2-B:2',3'-E! 1, 4!diazepines and their use in the treatment of HIV infection
PL192361B1 (pl) *	1997-08-25	2006-10-31	Boehringer Ingelheim Pharma	Kompozycja farmaceutyczna hemihydratu newirapiny i sposób wytwarzania wodnej zawiesiny hemihydratu newirapiny
DE10023492A1 (de) *	2000-05-09	2001-11-22	Schering Ag	Aza- und Polyazanthranylamide und deren Verwendung als Arzneimittel
US6878714B2 (en)	2001-01-12	2005-04-12	Amgen Inc.	Substituted alkylamine derivatives and methods of use
US7102009B2 (en)	2001-01-12	2006-09-05	Amgen Inc.	Substituted amine derivatives and methods of use
US6995162B2 (en)	2001-01-12	2006-02-07	Amgen Inc.	Substituted alkylamine derivatives and methods of use
US7105682B2 (en)	2001-01-12	2006-09-12	Amgen Inc.	Substituted amine derivatives and methods of use
US7307088B2 (en)	2002-07-09	2007-12-11	Amgen Inc.	Substituted anthranilic amide derivatives and methods of use
US8466144B2 (en)	2004-07-16	2013-06-18	Proteosys Ag	Muscarinic antagonists with parp and sir modulating activity as cytoprotective agents
US8247556B2 (en)	2005-10-21	2012-08-21	Amgen Inc.	Method for preparing 6-substituted-7-aza-indoles
PL2155169T3 (pl)	2007-06-08	2016-09-30		Formulacja newirapiny o przedłużonym uwalnianiu
WO2010081825A2 (fr)	2009-01-13	2010-07-22	Proteosys Ag	Pirenzépine en tant qu'agent utilisé dans le traitement du cancer
CN107428747A (zh)	2014-11-25	2017-12-01	拜耳制药股份公司	取代的吡啶并苯并二氮杂*酮衍生物及其用途
EP3153157A1 (fr)	2015-10-09	2017-04-12	Teva Pharmaceutical Works Private Limited Company	Composition pharmaceutique à libération prolongée de névirapine
CN107382848A (zh) *	2017-07-15	2017-11-24	河北蓝泰化工科技有限公司	一种烟酰胺化合物及其制备方法和应用
CN116606243A (zh) *	2023-05-19	2023-08-18	中科苏州药物研究院	一种安全高效合成奈伟拉平中间体的新工艺

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA658624A (en) *		1963-02-26	Schmutz Jean	Diazepine derivatives
CA783570A (en) *		1968-04-23	Schmidt Gunther	5,6-dihydro-6-oxo-11h-pyrido (2,3-b) (1,4)-benzodiazepines
CA554134A (fr) *		1958-03-11	Hoffmann Karl	Composes thia-aza-cycloheptadiene et procede pour leur fabrication
DE3643666A1 (de) *	1986-12-20	1988-06-30	Thomae Gmbh Dr K	Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3726908A1 (de) *	1987-08-13	1989-02-23	Thomae Gmbh Dr K	Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3735895A1 (de) *	1987-10-23	1989-05-03	Thomae Gmbh Dr K	Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DK0393529T3 (da) *	1989-04-20	1993-11-15	Boehringer Ingelheim Pharma	5,11-Dihydro-6H-dipyrido(3,2-b:2,3-e)(1,4)diazepin-6-oner og deres anvendelse ved forhindring eller behandling af AIDS
DE69031845T2 (de) *	1989-04-20	1998-05-07	Boehringer Ingelheim Pharma	6,11-Dihydro-5H-pyrido(2,3-b)(1,5)benzodiazepin-5-one und Thione und ihre Verwendung für die Vorbeugung oder Behandlung von AIDS
EP0410148B1 (fr) *	1989-06-28	1994-04-06	Boehringer Ingelheim Pharmaceuticals Inc.	5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazépin-6-ones et -thiones et leur utilisation pour la prévention ou le traitement du SIDA

1990
- 1990-11-15 CA CA002030056A patent/CA2030056C/fr not_active Expired - Lifetime
- 1990-11-16 IL IL9636790A patent/IL96367A/xx active IP Right Grant
- 1990-11-16 DE DE69033003T patent/DE69033003T2/de not_active Expired - Lifetime
- 1990-11-16 NZ NZ236105A patent/NZ236105A/en unknown
- 1990-11-16 IE IE414190A patent/IE904141A1/en not_active IP Right Cessation
- 1990-11-16 OA OA59896A patent/OA09852A/en unknown
- 1990-11-16 EP EP90121954A patent/EP0429987B1/fr not_active Expired - Lifetime
- 1990-11-16 AT AT90121954T patent/ATE177744T1/de active
- 1990-11-16 PT PT95919A patent/PT95919B/pt not_active IP Right Cessation
- 1990-11-16 FI FI905674A patent/FI94529C/fi active IP Right Grant
- 1990-11-16 DK DK90121954T patent/DK0429987T3/da active
- 1990-11-16 NO NO904986A patent/NO175478C/no not_active IP Right Cessation
- 1990-11-16 DE DE1999175051 patent/DE19975051I2/de active Active
- 1990-11-16 AP APAP/P/1990/000224A patent/AP179A/en active
- 1990-11-16 ES ES90121954T patent/ES2130114T3/es not_active Expired - Lifetime
- 1990-11-16 UA UA5011559A patent/UA34420C2/uk unknown
- 1990-11-19 AU AU66732/90A patent/AU630251B2/en not_active Expired
1992
- 1992-05-06 RU SU925011559A patent/RU2040527C1/ru active
1999
- 1999-04-30 GR GR990401182T patent/GR3030100T3/el unknown
- 1999-04-30 LU LU90393C patent/LU90393I2/fr unknown
- 1999-06-29 NO NO1999013C patent/NO1999013I1/no unknown
- 1999-07-27 NL NL990022C patent/NL990022I2/nl unknown

Also Published As

Publication number	Publication date
NO904986L (no)	1991-05-21
AU630251B2 (en)	1992-10-22
FI94529C (fi)	1995-09-25
PT95919B (pt)	1998-01-30
NL990022I2 (nl)	2007-11-01
GR3030100T3 (en)	1999-07-30
OA09852A (en)	1994-08-15
ES2130114T3 (es)	1999-07-01
NO1999013I1 (no)	1999-06-29
UA34420C2 (uk)	2001-03-15
AU6673290A (en)	1991-05-23
NL990022I1 (nl)	1999-10-01
DE69033003D1 (de)	1999-04-22
EP0429987B1 (fr)	1999-03-17
RU2040527C1 (ru)	1995-07-25
FI905674A7 (fi)	1991-05-18
NO175478B (no)	1994-07-11
EP0429987A2 (fr)	1991-06-05
NO175478C (no)	1994-10-19
IE904141A1 (en)	1991-05-22
AP179A (en)	1992-04-30
IL96367A (en)	1997-02-18
CA2030056C (fr)	1995-10-17
ATE177744T1 (de)	1999-04-15
NO904986D0 (no)	1990-11-16
FI905674A0 (fi)	1990-11-16
EP0429987A3 (en)	1992-01-22
PT95919A (pt)	1991-09-13
HK1011025A1 (en)	1999-07-02
DE69033003T2 (de)	1999-09-16
CA2030056A1 (fr)	1991-05-18
AP9000224A0 (en)	1991-01-31
NZ236105A (en)	1994-04-27
FI94529B (fi)	1995-06-15
DE19975051I2 (de)	2004-05-06
DK0429987T3 (da)	1999-10-11

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