IL97520A - Tanidap as an inhibitor of neutrophil release by neutrophils - Google Patents

Tanidap as an inhibitor of neutrophil release by neutrophils

Info

Publication number
IL97520A
IL97520A IL9752091A IL9752091A IL97520A IL 97520 A IL97520 A IL 97520A IL 9752091 A IL9752091 A IL 9752091A IL 9752091 A IL9752091 A IL 9752091A IL 97520 A IL97520 A IL 97520A
Authority
IL
Israel
Prior art keywords
tenidap
elastase
pharmaceutically
neutrophils
acceptable base
Prior art date
Application number
IL9752091A
Other languages
English (en)
Hebrew (he)
Other versions
IL97520A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL97520A0 publication Critical patent/IL97520A0/xx
Publication of IL97520A publication Critical patent/IL97520A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL9752091A 1990-03-19 1991-03-12 Tanidap as an inhibitor of neutrophil release by neutrophils IL97520A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/495,888 US5006547A (en) 1990-03-19 1990-03-19 Tenidap as an inhibitor of the release of elastase by neutrophils

Publications (2)

Publication Number Publication Date
IL97520A0 IL97520A0 (en) 1992-06-21
IL97520A true IL97520A (en) 1995-12-31

Family

ID=23970396

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9752091A IL97520A (en) 1990-03-19 1991-03-12 Tanidap as an inhibitor of neutrophil release by neutrophils

Country Status (17)

Country Link
US (1) US5006547A (fr)
EP (1) EP0448261B1 (fr)
JP (1) JPH0678230B2 (fr)
KR (1) KR960016511B1 (fr)
AT (1) ATE133071T1 (fr)
AU (1) AU629109B2 (fr)
CA (1) CA2038410C (fr)
DE (1) DE69116404T2 (fr)
DK (1) DK0448261T3 (fr)
HU (1) HU212492B (fr)
IE (1) IE70732B1 (fr)
IL (1) IL97520A (fr)
MY (1) MY107227A (fr)
NZ (1) NZ237450A (fr)
PH (1) PH27229A (fr)
PT (1) PT97062B (fr)
ZA (1) ZA911980B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008283A (en) * 1990-03-19 1991-04-16 Pfizer Inc. Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
US5122534A (en) * 1991-02-08 1992-06-16 Pfizer Inc. Use of tenidap to reduce total serum cholesterol, ldl cholesterol and triglycerides
US5545656A (en) * 1995-04-05 1996-08-13 Pfizer Inc. 2-Oxidole-1-carboxamide pharmaceutical agents for the treatment of alzheimer's disease
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
JP2005503772A (ja) * 2001-05-02 2005-02-10 センター フォー ブラッド リサーチ インコーポレイテッド エラスターゼインヒビター分泌のモジュレータ
DK2026651T3 (da) 2006-03-08 2013-07-08 Cortria Corp Kombinationsterapi med ikke-selektive COX-inhibitorer til forebyggelse af COX-relaterede maveskader
EP2886541A1 (fr) * 2013-12-19 2015-06-24 Sanofi Dérivés d'oxindole, leur préparation et leur utilisation thérapeutique pour traiter les troubles liés à l'AMPK

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4678802A (en) * 1985-07-09 1987-07-07 Pfizer Inc. 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
UA25898A1 (uk) * 1987-02-02 1999-02-26 Пфайзер Інк. Спосіб одержаhhя кристалічhої hатрієвої солі 5-хлор-3-(2-теhоїл)-2-оксііhдол-1-карбоксаміду
EP0287196B1 (fr) * 1987-02-18 1994-11-23 Beecham Group Plc Dérivés de l'indole, un procédé pour leur préparation et compositions pharmaceutiques les contenant
US4861794A (en) * 1988-04-13 1989-08-29 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
US4853409A (en) * 1988-04-13 1989-08-01 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
DE3814504A1 (de) * 1988-04-29 1989-11-09 Bayer Ag (alpha)-substituierte 4-(chinolin-2-yl-methoxy)phenylessigsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
DE69116404D1 (de) 1996-02-29
NZ237450A (en) 1997-02-24
EP0448261B1 (fr) 1996-01-17
DE69116404T2 (de) 1996-05-30
KR910016327A (ko) 1991-11-05
AU629109B2 (en) 1992-09-24
HUT60622A (en) 1992-10-28
PT97062A (pt) 1991-10-31
HU212492B (en) 1996-07-29
IL97520A0 (en) 1992-06-21
MY107227A (en) 1995-10-31
IE70732B1 (en) 1996-12-11
IE910861A1 (en) 1991-09-25
CA2038410C (fr) 1995-01-24
AU7358691A (en) 1992-08-06
EP0448261A3 (en) 1992-04-08
PH27229A (en) 1993-05-04
JPH04234814A (ja) 1992-08-24
ATE133071T1 (de) 1996-02-15
KR960016511B1 (ko) 1996-12-14
US5006547A (en) 1991-04-09
DK0448261T3 (da) 1996-02-12
PT97062B (pt) 1998-07-31
JPH0678230B2 (ja) 1994-10-05
HU910871D0 (en) 1991-09-30
ZA911980B (en) 1992-10-28
EP0448261A2 (fr) 1991-09-25

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees