IL97585A - Pharmaceutical iodine compositions - Google Patents

Pharmaceutical iodine compositions

Info

Publication number: IL97585A
Authority: IL; Israel
Prior art keywords: iodine; weight; range; composition according; iodate
Prior art date: 1990-03-21

Application number

IL9758591A

Other languages

English (en)

Other versions

IL97585A0 (en

Original Assignee

Euro Celtique Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-03-21

Filing date

1991-03-18

Publication date

1995-05-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10672991&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL97585(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-03-18 Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa

1992-06-21 Publication of IL97585A0 publication Critical patent/IL97585A0/xx

1995-05-26 Publication of IL97585A publication Critical patent/IL97585A/en

Links

239000011630 iodine Substances 0.000 title claims abstract description 45
229910052740 iodine Inorganic materials 0.000 title claims abstract description 45
ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 title claims abstract description 41
239000000203 mixture Substances 0.000 title claims description 29
-1 iodate ions Chemical class 0.000 claims abstract description 16
239000000126 substance Substances 0.000 claims abstract description 12
239000007864 aqueous solution Substances 0.000 claims abstract description 7
PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims abstract description 6
239000008194 pharmaceutical composition Substances 0.000 claims abstract description 4
239000000243 solution Substances 0.000 claims description 13
230000000536 complexating effect Effects 0.000 claims description 3
238000004519 manufacturing process Methods 0.000 claims description 3
229920000642 polymer Polymers 0.000 claims description 3
229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 3
239000001267 polyvinylpyrrolidone Substances 0.000 claims description 3
235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 3
239000004094 surface-active agent Substances 0.000 claims description 3
239000003021 water soluble solvent Substances 0.000 claims description 2
239000002904 solvent Substances 0.000 claims 1
ICIWUVCWSCSTAQ-UHFFFAOYSA-M iodate Chemical compound [O-]I(=O)=O ICIWUVCWSCSTAQ-UHFFFAOYSA-M 0.000 abstract description 7
206010015150 Erythema Diseases 0.000 description 13
231100000321 erythema Toxicity 0.000 description 13
238000011282 treatment Methods 0.000 description 8
238000000034 method Methods 0.000 description 7
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 description 4
238000006243 chemical reaction Methods 0.000 description 4
230000002070 germicidal effect Effects 0.000 description 4
239000008213 purified water Substances 0.000 description 4
CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 description 3
KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 3
229920000153 Povidone-iodine Polymers 0.000 description 3
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
238000004458 analytical method Methods 0.000 description 3
230000017531 blood circulation Effects 0.000 description 3
229960001621 povidone-iodine Drugs 0.000 description 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
230000000844 anti-bacterial effect Effects 0.000 description 2
239000007979 citrate buffer Substances 0.000 description 2
239000003814 drug Substances 0.000 description 2
229940005633 iodate ion Drugs 0.000 description 2
229920004918 nonoxynol-9 Polymers 0.000 description 2
229940087419 nonoxynol-9 Drugs 0.000 description 2
239000008363 phosphate buffer Substances 0.000 description 2
JLKDVMWYMMLWTI-UHFFFAOYSA-M potassium iodate Chemical compound [K+].[O-]I(=O)=O JLKDVMWYMMLWTI-UHFFFAOYSA-M 0.000 description 2
239000001230 potassium iodate Substances 0.000 description 2
235000006666 potassium iodate Nutrition 0.000 description 2
229940093930 potassium iodate Drugs 0.000 description 2
238000003892 spreading Methods 0.000 description 2
238000003860 storage Methods 0.000 description 2
FBWNMEQMRUMQSO-UHFFFAOYSA-N tergitol NP-9 Chemical compound CCCCCCCCCC1=CC=C(OCCOCCOCCOCCOCCOCCOCCOCCOCCO)C=C1 FBWNMEQMRUMQSO-UHFFFAOYSA-N 0.000 description 2
238000012360 testing method Methods 0.000 description 2
229920002554 vinyl polymer Polymers 0.000 description 2
ZAUYNCUCMJDAHW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;hydrogen peroxide;molecular iodine Chemical compound OO.II.C=CN1CCCC1=O ZAUYNCUCMJDAHW-UHFFFAOYSA-N 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
241000124008 Mammalia Species 0.000 description 1
206010030113 Oedema Diseases 0.000 description 1
229910019142 PO4 Inorganic materials 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
239000004141 Sodium laurylsulphate Substances 0.000 description 1
241000191967 Staphylococcus aureus Species 0.000 description 1
206010042618 Surgical procedure repeated Diseases 0.000 description 1
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
229910052782 aluminium Inorganic materials 0.000 description 1
239000004411 aluminium Substances 0.000 description 1
238000000540 analysis of variance Methods 0.000 description 1
230000001580 bacterial effect Effects 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
239000000872 buffer Substances 0.000 description 1
239000000969 carrier Substances 0.000 description 1
125000002091 cationic group Chemical group 0.000 description 1
230000000052 comparative effect Effects 0.000 description 1
239000008139 complexing agent Substances 0.000 description 1
239000000470 constituent Substances 0.000 description 1
230000007423 decrease Effects 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
239000003599 detergent Substances 0.000 description 1
239000012895 dilution Substances 0.000 description 1
238000010790 dilution Methods 0.000 description 1
239000003937 drug carrier Substances 0.000 description 1
230000003628 erosive effect Effects 0.000 description 1
239000000499 gel Substances 0.000 description 1
239000001257 hydrogen Substances 0.000 description 1
229910052739 hydrogen Inorganic materials 0.000 description 1
XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
238000000338 in vitro Methods 0.000 description 1
XMBWDFGMSWQBCA-UHFFFAOYSA-M iodide Chemical compound [I-] XMBWDFGMSWQBCA-UHFFFAOYSA-M 0.000 description 1
229940006461 iodide ion Drugs 0.000 description 1
239000002085 irritant Substances 0.000 description 1
231100000021 irritant Toxicity 0.000 description 1
239000000463 material Substances 0.000 description 1
238000005259 measurement Methods 0.000 description 1
229920000847 nonoxynol Polymers 0.000 description 1
239000002674 ointment Substances 0.000 description 1
239000003960 organic solvent Substances 0.000 description 1
239000003973 paint Substances 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
239000010452 phosphate Substances 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
238000011321 prophylaxis Methods 0.000 description 1
239000000344 soap Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
239000011697 sodium iodate Substances 0.000 description 1
235000015281 sodium iodate Nutrition 0.000 description 1
229940032753 sodium iodate Drugs 0.000 description 1
235000019333 sodium laurylsulphate Nutrition 0.000 description 1
239000008279 sol Substances 0.000 description 1
238000007619 statistical method Methods 0.000 description 1
230000008961 swelling Effects 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
230000000007 visual effect Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/18—Iodine; Compounds thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Inorganic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Apparatus For Disinfection Or Sterilisation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

IL9758591A 1990-03-21 1991-03-18 Pharmaceutical iodine compositions IL97585A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB909006346A GB9006346D0 (en)	1990-03-21	1990-03-21	Pharmaceutical composition

Publications (2)

Publication Number	Publication Date
IL97585A0 IL97585A0 (en)	1992-06-21
IL97585A true IL97585A (en)	1995-05-26

Family

ID=10672991

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL9758591A IL97585A (en)	1990-03-21	1991-03-18	Pharmaceutical iodine compositions

Country Status (16)

Country	Link
US (1)	US5709851A (ja)
EP (1)	EP0448288B1 (ja)
JP (1)	JP3240061B2 (ja)
AT (1)	ATE144709T1 (ja)
CA (1)	CA2038637C (ja)
DE (1)	DE69122901T2 (ja)
DK (1)	DK0448288T3 (ja)
ES (1)	ES2096621T3 (ja)
FI (1)	FI102354B (ja)
GB (2)	GB9006346D0 (ja)
GR (1)	GR3021986T3 (ja)
IE (1)	IE910922A1 (ja)
IL (1)	IL97585A (ja)
NO (1)	NO304410B1 (ja)
NZ (1)	NZ237394A (ja)
ZA (1)	ZA912070B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2609895A (en) *	1995-06-09	1997-01-09	Shenzhen Neptunus Group Co., Ltd.	A preparation of potassium iodate
US5643608A (en) *	1996-03-01	1997-07-01	West Agro, Inc.	Low pH germicidal iodine compositions having enhanced stability
US5897872A (en) *	1997-11-12	1999-04-27	Picciano; Dante J.	Iodine-containing nasal moisturizing saline solution
US6171611B1 (en)	1997-11-12	2001-01-09	Dante J. Picciano	Iodine-containing nasal moisturizing saline and mouthwash solutions
RU2271337C2 (ru) *	2001-09-24	2006-03-10	Париченко Александр Валентинович	Способ получения соляно-кислого раствора йодхлорида и устройство для осуществления этого способа
RU2210533C1 (ru) *	2002-06-24	2003-08-20	Талановский Владимир Федорович	Способ получения йодата калия (варианты)
US20040242449A1 (en)	2003-06-02	2004-12-02	Joshi Nayan H.	Nitric acid and chromic acid-free compositions and process for cleaning aluminum and aluminum alloy surfaces
US20050262811A1 (en) *	2004-05-27	2005-12-01	Mahmood Mohiuddin	Sterilization process for iodine-containing antimicrobial topical solutions
GB201114725D0 (en)	2011-08-25	2011-10-12	Altacor Ltd	Ophthalmic formulations
JP2017517484A (ja)	2014-03-31	2017-06-29	イオテックインターナショナル，インコーポレイテッド	非錯体化ヨウ素の安定な組成物及び使用方法
DE102014010694A1 (de)	2014-07-09	2016-01-28	Beuth Hochschule Für Technik Berlin	Jod enthaltende pharmazeutische Zusammensetzung mit antimikrobiellen Eigenschaften sowie Verfahren zur Herstellung

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2826532A (en) *	1952-04-15	1958-03-11	Gen Aniline & Film Corp	Process of stabilizing polyvinyl pyrrolidone-iodine compositions
US2754245A (en) *	1954-09-23	1956-07-10	Gen Aniline & Film Corp	Interhalogen adducts of polyvinyl pyrrolidone
DE2540170C3 (de) *	1975-09-10	1979-01-18	Basf Ag, 6700 Ludwigshafen	Verwendung von in organischer Lösung hergestelltem Polyvinylpyrrolidon zur Herstellung von stabilen wäßrigen PoIyvinylpyrrolidon-Jod-Lösungen
US4113857A (en) *	1977-05-16	1978-09-12	The Purdue Frederick Company	Process for the preparation of iodophor compounds and methods for stabilizing iodophor pharmaceutical compositions containing the same
US4323557A (en) *	1979-07-31	1982-04-06	Minnesota Mining & Manufacturing Company	Pressure-sensitive adhesive containing iodine
US4271149A (en) *	1979-09-21	1981-06-02	West Agro-Chemical, Inc.	Germicidal iodine compositions with enhanced iodine stability
DE2942179A1 (de) *	1979-10-18	1981-05-07	Basf Ag, 6700 Ludwigshafen	Verfahren zur herstellung von pvp-iod
US4427631A (en) *	1982-05-27	1984-01-24	Euroceltique, S.A.	Povidone irradiation
IL70972A (en) *	1983-03-02	1987-10-30	Euro Celtique Sa	Method of producing standardized iodophor preparations and iodophor preparations produced thereby
US4946673A (en) *	1984-05-31	1990-08-07	Euroceltique, S.A.	Iodine-containing germicidal preparations and method of controlling germicidal activity
US4575491A (en) *	1984-05-31	1986-03-11	Euroceltique, S.A.	Method of controlling and determining germicidal activity
HU197513B (en) *	1986-04-07	1989-04-28	Biogal Gyogyszergyar	Process for producing pvp-i complex and chirurgic hand disinfectant comprising sam as active ingredient
DE3856447T2 (de) *	1987-07-01	2001-06-28	Novapharm Research Pty. Ltd., Rosebery	Biozide zusammensetzung

1990
- 1990-03-21 GB GB909006346A patent/GB9006346D0/en active Pending
1991
- 1991-03-08 GB GB9104968A patent/GB2242629B/en not_active Expired - Lifetime
- 1991-03-12 NZ NZ237394A patent/NZ237394A/en unknown
- 1991-03-14 ES ES91302161T patent/ES2096621T3/es not_active Expired - Lifetime
- 1991-03-14 DE DE69122901T patent/DE69122901T2/de not_active Expired - Lifetime
- 1991-03-14 DK DK91302161.4T patent/DK0448288T3/da active
- 1991-03-14 AT AT91302161T patent/ATE144709T1/de not_active IP Right Cessation
- 1991-03-14 EP EP91302161A patent/EP0448288B1/en not_active Expired - Lifetime
- 1991-03-18 IL IL9758591A patent/IL97585A/en not_active IP Right Cessation
- 1991-03-19 CA CA002038637A patent/CA2038637C/en not_active Expired - Lifetime
- 1991-03-20 NO NO911119A patent/NO304410B1/no not_active IP Right Cessation
- 1991-03-20 JP JP05716891A patent/JP3240061B2/ja not_active Expired - Lifetime
- 1991-03-20 ZA ZA912070A patent/ZA912070B/xx unknown
- 1991-03-20 IE IE092291A patent/IE910922A1/en not_active IP Right Cessation
- 1991-03-20 FI FI911365A patent/FI102354B/fi active
1994
- 1994-05-16 US US08/243,534 patent/US5709851A/en not_active Expired - Lifetime
1996
- 1996-12-11 GR GR960403421T patent/GR3021986T3/el unknown

Also Published As

Publication number	Publication date
DE69122901T2 (de)	1997-03-20
FI102354B1 (fi)	1998-11-30
ATE144709T1 (de)	1996-11-15
FI911365A0 (fi)	1991-03-20
FI911365L (fi)	1991-09-22
CA2038637C (en)	2002-11-12
EP0448288B1 (en)	1996-10-30
GB9006346D0 (en)	1990-05-16
JP3240061B2 (ja)	2001-12-17
AU7274191A (en)	1991-10-03
NO304410B1 (no)	1998-12-14
GR3021986T3 (en)	1997-03-31
FI102354B (fi)	1998-11-30
ZA912070B (en)	1992-01-29
IL97585A0 (en)	1992-06-21
JPH04217628A (ja)	1992-08-07
NO911119D0 (no)	1991-03-20
ES2096621T3 (es)	1997-03-16
NO911119L (no)	1991-09-23
GB2242629B (en)	1994-10-19
GB9104968D0 (en)	1991-04-24
DE69122901D1 (de)	1996-12-05
DK0448288T3 (da)	1996-11-25
IE910922A1 (en)	1991-09-25
EP0448288A1 (en)	1991-09-25
NZ237394A (en)	1992-12-23
CA2038637A1 (en)	1991-09-22
GB2242629A (en)	1991-10-09
AU636721B2 (en)	1993-05-06
US5709851A (en)	1998-01-20

Legal Events

Date	Code	Title
1997-07-13	KB	Patent renewed
2001-07-24	KB	Patent renewed
2005-05-17	KB	Patent renewed
2009-09-15	KB	Patent renewed
2011-12-29	EXP	Patent expired

Publication	Publication Date	Title
DE60204322T2 (de)	2006-01-26	Stickstoffmonoxid bildende zusammensetzungen zur behandlung von nagelbettinfektionen
US5122370A (en)	1992-06-16	Method for treating acne vulgaris with a composition containing a stable, high purity, substantially anhydrous complex of PVP-H2 O.sub.2
EP0101178B1 (en)	1987-09-02	Topical anti-inflammatory compositions
EP0487066B1 (en)	1994-11-30	Disinfectant composition
DE69629519T2 (de)	2004-06-24	Stable Komplexen von vernetzten Polyvinylpyrrolidone und Iod und Verfahren zur Herstellung
CA2038637C (en)	2002-11-12	Pharmaceutical iodine compositions
KR20010108469A (ko)	2001-12-07	항진균 조성물
WO1990010020A1 (en)	1990-09-07	Novel compositions containing hyaluronic acid associates and a process for preparing same
US4283421A (en)	1981-08-11	Anti-viral treatment
CA2364027C (en)	2011-09-06	Iodine preparation composition
KR910000144B1 (ko)	1991-01-21	표준화한 요오도퍼 제제의 제조방법
US4849215A (en)	1989-07-18	Pharmaceutical iodophor preparations with controlled iodine:iodide ratio and method of producing the same
WO1989007933A2 (en)	1989-09-08	Skin treatment formulations
JPS58148842A (ja)	1983-09-05	パンテノ−ル誘導体
US5002763A (en)	1991-03-26	Water soluble complexes of polyvinylpyrrolidone, hydrogen chloride and iodine and process for making the same
JPS644485B2 (ja)	1989-01-25
US4939272A (en)	1990-07-03	Water soluble complexes of polyvinylpyrrolidone, hydrogen chloride and iodine and process for making the same
EP0914105A1 (en)	1999-05-12	Topical medicament comprising phenolic biocide and choline
JPH0720870B2 (ja)	1995-03-08	知覚過敏抑制剤
JPS6368508A (ja)	1988-03-28	殺菌消毒剤の製法