IN2009CN02154A - - Google Patents
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- Publication number
- IN2009CN02154A IN2009CN02154A IN2154CHN2009A IN2009CN02154A IN 2009CN02154 A IN2009CN02154 A IN 2009CN02154A IN 2154CHN2009 A IN2154CHN2009 A IN 2154CHN2009A IN 2009CN02154 A IN2009CN02154 A IN 2009CN02154A
- Authority
- IN
- India
- Prior art keywords
- alkyl
- nr5r6
- proviso
- heteroatom
- chosen
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000005842 heteroatom Chemical group 0.000 abstract 3
- 125000004452 carbocyclyl group Chemical group 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- NTURXXALYKMFBQ-UHFFFAOYSA-N [N].C1=NC=C2NC=NC2=N1 Chemical compound [N].C1=NC=C2NC=NC2=N1 NTURXXALYKMFBQ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- SNVLJLYUUXKWOJ-UHFFFAOYSA-N methylidenecarbene Chemical compound C=[C] SNVLJLYUUXKWOJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 0 Cc1c(C)cc(C*=C)cc1 Chemical compound Cc1c(C)cc(C*=C)cc1 0.000 description 7
- SOASYFLYKZHCCT-UHFFFAOYSA-N CC(CCc1ccccc1C)=C Chemical compound CC(CCc1ccccc1C)=C SOASYFLYKZHCCT-UHFFFAOYSA-N 0.000 description 1
- YJFATKLYOXCPBK-UHFFFAOYSA-N CCCC(CCC)CC[n]1c(-c(cc2)ccc2C#N)nc2c1nc(CCc(cccc1)c1Cl)nc2 Chemical compound CCCC(CCC)CC[n]1c(-c(cc2)ccc2C#N)nc2c1nc(CCc(cccc1)c1Cl)nc2 YJFATKLYOXCPBK-UHFFFAOYSA-N 0.000 description 1
- HSVUACDXZURDTL-WMCAAGNKSA-N CCCCCC(C)C([C@H]1C=CC=C(C)C1)=C Chemical compound CCCCCC(C)C([C@H]1C=CC=C(C)C1)=C HSVUACDXZURDTL-WMCAAGNKSA-N 0.000 description 1
- FYJXLWXSAMWFHW-UHFFFAOYSA-N CCCN(CC1)CC[O]1[I]1C([IH]C(NCC2C=CC=CC2F)NC2)=C2C=C1C1=C(C)C(C)CCC1 Chemical compound CCCN(CC1)CC[O]1[I]1C([IH]C(NCC2C=CC=CC2F)NC2)=C2C=C1C1=C(C)C(C)CCC1 FYJXLWXSAMWFHW-UHFFFAOYSA-N 0.000 description 1
- HPRMNOHMMYKHIW-JCZBKMKOSA-N CC[C@H](C)CC([C@@H](C)C[C@@H]1C)C1I Chemical compound CC[C@H](C)CC([C@@H](C)C[C@@H]1C)C1I HPRMNOHMMYKHIW-JCZBKMKOSA-N 0.000 description 1
- HYFLWBNQFMXCPA-UHFFFAOYSA-N CCc1c(C)cccc1 Chemical compound CCc1c(C)cccc1 HYFLWBNQFMXCPA-UHFFFAOYSA-N 0.000 description 1
- WBZPJYVOOIYMKI-YUZLPWPTSA-N C[C@@]12C(I)=C(CCCC=C)C#CC1C2 Chemical compound C[C@@]12C(I)=C(CCCC=C)C#CC1C2 WBZPJYVOOIYMKI-YUZLPWPTSA-N 0.000 description 1
- QTZGHUUECFAZQP-UHFFFAOYSA-N Fc(cc1)ccc1-c1nc2cnc(NCc(cccc3)c3Cl)nc2[n]1CCC1CCNCC1 Chemical compound Fc(cc1)ccc1-c1nc2cnc(NCc(cccc3)c3Cl)nc2[n]1CCC1CCNCC1 QTZGHUUECFAZQP-UHFFFAOYSA-N 0.000 description 1
- PREQZIDCLYIERV-UHFFFAOYSA-N Fc1c(C[N-]c2ncc(C=C(C3C4CCNCC4)c4ccccc4F)c3n2)cccc1 Chemical compound Fc1c(C[N-]c2ncc(C=C(C3C4CCNCC4)c4ccccc4F)c3n2)cccc1 PREQZIDCLYIERV-UHFFFAOYSA-N 0.000 description 1
- ZZMATCATVCPAJU-YRNVUSSQSA-N I/C=C/CCCCC1CCCCC1 Chemical compound I/C=C/CCCCC1CCCCC1 ZZMATCATVCPAJU-YRNVUSSQSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85339606P | 2006-10-20 | 2006-10-20 | |
| PCT/US2007/081899 WO2008051826A2 (en) | 2006-10-20 | 2007-10-19 | Purines as pkc-theta inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2009CN02154A true IN2009CN02154A (pt) | 2015-08-07 |
Family
ID=39111415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2154CHN2009 IN2009CN02154A (pt) | 2006-10-20 | 2007-10-19 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20110046131A1 (pt) |
| EP (1) | EP2078019A2 (pt) |
| JP (1) | JP2010507581A (pt) |
| KR (1) | KR20090075854A (pt) |
| CN (1) | CN101657453B (pt) |
| AU (1) | AU2007309167A1 (pt) |
| BR (1) | BRPI0717435A2 (pt) |
| CA (1) | CA2666940A1 (pt) |
| CO (1) | CO6160294A2 (pt) |
| EC (1) | ECSP099342A (pt) |
| IL (1) | IL198080A0 (pt) |
| IN (1) | IN2009CN02154A (pt) |
| MX (1) | MX2009004154A (pt) |
| NO (1) | NO20091597L (pt) |
| RU (1) | RU2009118963A (pt) |
| WO (1) | WO2008051826A2 (pt) |
| ZA (1) | ZA200902640B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7989459B2 (en) * | 2006-02-17 | 2011-08-02 | Pharmacopeia, Llc | Purinones and 1H-imidazopyridinones as PKC-theta inhibitors |
| US20090281075A1 (en) * | 2006-02-17 | 2009-11-12 | Pharmacopeia, Inc. | Isomeric purinones and 1h-imidazopyridinones as pkc-theta inhibitors |
| KR20080107466A (ko) * | 2006-03-09 | 2008-12-10 | 파마코페이아, 인코포레이티드 | 대사 장애 치료용 8-헤테로아릴퓨린 ｍｎｋ2 억제제 |
| JP2009541332A (ja) * | 2006-06-23 | 2009-11-26 | パラテック ファーマシューティカルズ インコーポレイテッド | 転写因子調節化合物およびその使用法 |
| WO2011066211A1 (en) * | 2009-11-24 | 2011-06-03 | Glaxosmithkline Llc | Azabenzimidazoles as fatty acid synthase inhibitors |
| JP2013518114A (ja) * | 2010-01-27 | 2013-05-20 | バーテックス ファーマシューティカルズ インコーポレイテッド | ピラゾロピリミジンキナーゼ阻害剤 |
| KR20130051507A (ko) | 2010-09-15 | 2013-05-20 | 에프. 호프만-라 로슈 아게 | 아자벤조티아졸 화합물, 조성물 및 사용 방법 |
| RU2014113236A (ru) * | 2011-09-20 | 2015-10-27 | Ф. Хоффманн-Ля Рош Аг | Соединения имидазопиридина, композиции и способы применения |
| AU2015309686B2 (en) * | 2014-08-25 | 2020-05-14 | Epiaxis Therapeutics Pty Ltd | Compositions for modulating cancer stem cells and uses therefor |
| US11986480B2 (en) | 2017-02-03 | 2024-05-21 | Tohoku University | Heterocyclic compound |
| CA3082055A1 (en) * | 2017-11-08 | 2019-05-16 | Epiaxis Therapeutics Pty Ltd | Immunogenic compositions and uses therefor |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0470543A1 (de) * | 1990-08-10 | 1992-02-12 | Dr. Karl Thomae GmbH | Heterocyclische Imidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zur ihrer Herstellung |
| CA2309350C (en) * | 1997-11-12 | 2007-04-03 | Mitsubishi Chemical Corporation | Purine derivatives and medicaments comprising the same as active ingredient |
| US20050165232A1 (en) * | 2002-05-13 | 2005-07-28 | Richard Beresis | Phenyl substituted imidaopyridines and phenyl substituted benzimidazoles |
| JP2004217582A (ja) * | 2003-01-16 | 2004-08-05 | Abbott Japan Co Ltd | ９ｈ−プリン誘導体 |
| US8153640B2 (en) * | 2004-10-29 | 2012-04-10 | Tibotec Pharmaceuticals Ltd. | HIV inhibiting bicyclic pyrimdine derivatives |
| US7723340B2 (en) * | 2005-01-13 | 2010-05-25 | Signal Pharmaceuticals, Llc | Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith |
| PT1853588E (pt) * | 2005-02-16 | 2008-08-25 | Astrazeneca Ab | Compostos químicos |
| WO2006091737A1 (en) * | 2005-02-24 | 2006-08-31 | Kemia, Inc. | Modulators of gsk-3 activity |
| KR20080107466A (ko) * | 2006-03-09 | 2008-12-10 | 파마코페이아, 인코포레이티드 | 대사 장애 치료용 8-헤테로아릴퓨린 ｍｎｋ2 억제제 |
-
2007
- 2007-10-19 AU AU2007309167A patent/AU2007309167A1/en not_active Abandoned
- 2007-10-19 EP EP07844441A patent/EP2078019A2/en not_active Withdrawn
- 2007-10-19 IN IN2154CHN2009 patent/IN2009CN02154A/en unknown
- 2007-10-19 CA CA002666940A patent/CA2666940A1/en not_active Abandoned
- 2007-10-19 WO PCT/US2007/081899 patent/WO2008051826A2/en not_active Ceased
- 2007-10-19 KR KR1020097009128A patent/KR20090075854A/ko not_active Withdrawn
- 2007-10-19 CN CN2007800418805A patent/CN101657453B/zh not_active Expired - Fee Related
- 2007-10-19 MX MX2009004154A patent/MX2009004154A/es not_active Application Discontinuation
- 2007-10-19 JP JP2009533556A patent/JP2010507581A/ja active Pending
- 2007-10-19 RU RU2009118963/04A patent/RU2009118963A/ru not_active Application Discontinuation
- 2007-10-19 BR BRPI0717435-7A patent/BRPI0717435A2/pt not_active IP Right Cessation
- 2007-10-19 US US12/445,862 patent/US20110046131A1/en not_active Abandoned
-
2009
- 2009-04-07 IL IL198080A patent/IL198080A0/en unknown
- 2009-04-16 ZA ZA200902640A patent/ZA200902640B/xx unknown
- 2009-04-20 CO CO09039704A patent/CO6160294A2/es unknown
- 2009-04-22 NO NO20091597A patent/NO20091597L/no not_active Application Discontinuation
- 2009-05-18 EC EC2009009342A patent/ECSP099342A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010507581A (ja) | 2010-03-11 |
| CA2666940A1 (en) | 2008-05-02 |
| WO2008051826A2 (en) | 2008-05-02 |
| IL198080A0 (en) | 2009-12-24 |
| WO2008051826A3 (en) | 2008-10-02 |
| NO20091597L (no) | 2009-07-14 |
| ZA200902640B (en) | 2010-05-26 |
| MX2009004154A (es) | 2009-09-09 |
| RU2009118963A (ru) | 2010-11-27 |
| ECSP099342A (es) | 2009-06-30 |
| AU2007309167A1 (en) | 2008-05-02 |
| BRPI0717435A2 (pt) | 2014-03-18 |
| CN101657453A (zh) | 2010-02-24 |
| KR20090075854A (ko) | 2009-07-09 |
| CO6160294A2 (es) | 2010-05-20 |
| EP2078019A2 (en) | 2009-07-15 |
| CN101657453B (zh) | 2013-06-12 |
| US20110046131A1 (en) | 2011-02-24 |
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