IS1975B - Seyði úr hákarlabrjóski með virkni gegn æðamyndunog æxlisbælandi áhrif; aðferð við framleiðslu þess - Google Patents

Seyði úr hákarlabrjóski með virkni gegn æðamyndunog æxlisbælandi áhrif; aðferð við framleiðslu þess

Info

Publication number
IS1975B
IS1975B IS4379A IS4379A IS1975B IS 1975 B IS1975 B IS 1975B IS 4379 A IS4379 A IS 4379A IS 4379 A IS4379 A IS 4379A IS 1975 B IS1975 B IS 1975B
Authority
IS
Iceland
Prior art keywords
supernatant
angiogenic
vivo
tumor
activity
Prior art date
Application number
IS4379A
Other languages
English (en)
Other versions
IS4379A (is
Inventor
Dupont Eric
Brazeau Paul
Juneau Christina
Original Assignee
Aeterna Zentaris Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aeterna Zentaris Inc. filed Critical Aeterna Zentaris Inc.
Publication of IS4379A publication Critical patent/IS4379A/is
Publication of IS1975B publication Critical patent/IS1975B/is

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
IS4379A 1994-04-28 1996-10-25 Seyði úr hákarlabrjóski með virkni gegn æðamyndunog æxlisbælandi áhrif; aðferð við framleiðslu þess IS1975B (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23401994A 1994-04-28 1994-04-28
US08/384,555 US5618925A (en) 1994-04-28 1995-02-03 Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof
PCT/CA1995/000233 WO1995032722A1 (en) 1994-04-28 1995-04-21 Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof

Publications (2)

Publication Number Publication Date
IS4379A IS4379A (is) 1996-10-25
IS1975B true IS1975B (is) 2005-01-14

Family

ID=26927471

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4379A IS1975B (is) 1994-04-28 1996-10-25 Seyði úr hákarlabrjóski með virkni gegn æðamyndunog æxlisbælandi áhrif; aðferð við framleiðslu þess

Country Status (24)

Country Link
US (2) US5618925A (is)
EP (1) EP0759765B1 (is)
JP (1) JPH09512563A (is)
KR (1) KR100378787B1 (is)
CN (2) CN1541656A (is)
AT (1) ATE224198T1 (is)
BG (1) BG62954B1 (is)
BR (1) BR9507552A (is)
CA (1) CA2188793C (is)
CZ (1) CZ290520B6 (is)
DE (1) DE69528258T2 (is)
DK (1) DK0759765T3 (is)
ES (1) ES2182900T3 (is)
FI (1) FI117375B (is)
HU (1) HU220784B1 (is)
IS (1) IS1975B (is)
NO (1) NO317674B1 (is)
NZ (1) NZ284407A (is)
PL (1) PL181981B1 (is)
PT (1) PT759765E (is)
RO (1) RO114868B1 (is)
RU (1) RU2156132C2 (is)
SI (1) SI0759765T1 (is)
WO (1) WO1995032722A1 (is)

Families Citing this family (60)

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US6380366B1 (en) * 1994-04-28 2002-04-30 Les Laboratoires Aeterna Inc. Shark cartilage extract:process of making, methods of using and compositions thereof
US5618925A (en) * 1994-04-28 1997-04-08 Les Laboratories Aeterna Inc. Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof
US6025334A (en) * 1994-04-28 2000-02-15 Les Laboratoires Aeterna Inc. Extracts of shark cartilage having anti-collagenolytic, anti-inflammatory, anti-angiogenic and anti-tumoral activities; process of making, methods of using and compositions thereof
US6028118A (en) * 1996-08-08 2000-02-22 Les Laboratoires Aeterna Inc. Methods of using extracts of shark cartilage
JPH11502514A (ja) * 1995-02-03 1999-03-02 レ ラボラトワール エテルナ インコーポレイティド サメ軟骨の抽出物、その製造法および使用
US5843920A (en) * 1996-09-16 1998-12-01 Biocell Technology, Llc Anionic saccharides for extraction of anti-angiogenic protein from cartilage
AU6639898A (en) * 1997-02-20 1998-09-09 Industrial Research Limited Angiogenesis inhibitors and activators from shark cartilage
CN1245993C (zh) 1997-03-11 2006-03-22 阿特纳赞塔里斯公司 用于治疗肿瘤的含有鲨鱼软骨提取物和抗肿瘤剂的药物组合物
WO1999002548A1 (en) * 1997-07-11 1999-01-21 Cv Technologies Inc. A preparation derived from shark cartilage for treatment of diseases related to excessive phf or excessive intracellular calcium
US5840342A (en) * 1997-09-17 1998-11-24 Raithaus; Lawrence R. Shark liver extract for stimulating the immune system
FR2778558B1 (fr) * 1998-05-12 2001-02-16 Oreal Utilisation d'inhibiteur de metalloproteinases pour induire et/ou stimuler la croissance des cheveux ou des poils et/ou freiner leur chute
ES2533255T3 (es) 1998-07-13 2015-04-08 Board Of Regents, The University Of Texas System Utilización de anticuerpos anti-aminofosfolípidos para el tratamiento del cáncer
US20020009501A1 (en) * 1998-07-23 2002-01-24 Eric Dupont Preparation of cartilage extracts using organic solvents
US6168807B1 (en) 1998-07-23 2001-01-02 Les Laboratoires Aeterna Inc. Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof
SI1107795T1 (en) 1998-09-04 2003-06-30 The Regents Of The University Of Michigan Thiomolybdate associated with at least one carbohydrate, and its use for preventing or treating diseases characterized by aberrant vascularization, such as cancer, wet type macular degeneration, rheumatoid arthritis
CN1064690C (zh) * 1998-09-10 2001-04-18 中国人民解放军海军医学研究所 鲨鱼软骨血管生成抑制因子及其分离纯化方法
US7361643B2 (en) 2000-02-09 2008-04-22 University Of Puerto Rico Methods for inhibiting angiogenesis
EP1343511A4 (en) * 2000-12-20 2005-06-01 Ind Res Ltd SHARK MEAT EXTRACT
AUPR222300A0 (en) * 2000-12-21 2001-01-25 Life Therapeutics Limited Electrophoresis device and method
US20030095981A1 (en) * 2001-05-30 2003-05-22 Kin-Ping Wong Compositions containing an active fraction isolated from ganoderma lucidum and methods of use
US20030087830A1 (en) * 2001-06-12 2003-05-08 Eric Dupont Low molecular weight components of cartilage, complexes of metals with amino acids, DI-peptides and analogs thereof; processes for preparation and therapeutic uses thereof
US6908627B2 (en) * 2001-06-21 2005-06-21 Mote Marine Laboratory Conditioned media for inhibiting growth of tumor cells
US7309501B2 (en) * 2001-06-21 2007-12-18 Mote Marine Laboratory Conditioned media to inhibit growth of tumor cells
CA2476126A1 (en) 2002-02-15 2003-08-21 Ocean Nutrition Canada Limited Shark cartilage extracts and use thereof for immunomodulation
RU2270023C2 (ru) * 2002-02-20 2006-02-20 Какухиро Ко., Лтд. Способ экстракции и очистки протеогликана хрящевого типа (варианты)
ES2524325T3 (es) 2002-07-15 2014-12-05 Board Of Regents, The University Of Texas System Anticuerpos seleccionados que se unen a aminofosfolípidos y su uso en el tratamiento del cáncer
JPWO2004083257A1 (ja) * 2003-03-20 2006-06-22 ホソカワミクロン株式会社 軟骨魚類から単離されたプロテオグリカンおよびその製造方法
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) * 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
ES2223291B1 (es) * 2003-08-06 2006-03-16 Bioiberica, S.A. Nuevo uso terapeutico de condroitin sulfato.
EP2338441B1 (en) 2003-12-11 2013-01-23 Isto Technologies Inc. Particulate cartilage system
EP1718283B1 (en) 2004-01-22 2013-03-06 University of Miami Topical co-enzyme q10 formulations and methods of use
CN100377741C (zh) * 2004-02-23 2008-04-02 江卫世 注射用复方骨肽及其制备工艺
US20050288796A1 (en) * 2004-06-23 2005-12-29 Hani Awad Native soft tissue matrix for therapeutic applications
US7837740B2 (en) * 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
WO2006059236A2 (en) * 2004-11-16 2006-06-08 Aeterna Zentaris Inc. Method of using cartilage extract for increasing blood parameters
US7815926B2 (en) * 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
EP1916964A4 (en) 2005-08-26 2015-11-04 Zimmer Inc IMPLANTS AND METHODS FOR THE REPAIR, REPLACEMENT AND TREATMENT OF JOINT DISEASES
AU2006292224B2 (en) 2005-09-19 2013-08-01 Histogenics Corporation Cell-support matrix and a method for preparation thereof
DE102006060247A1 (de) * 2006-09-15 2008-03-27 Ossacur Ag Differenzierung von Stammzellen
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
CA2684040C (en) 2007-04-12 2016-12-06 Isto Technologies, Inc. Method of forming an implant using a mold that mimics the shape of the tissue defect site and implant formed therefrom
EP2614837A1 (en) 2007-11-09 2013-07-17 Affitech Research AS Anti-VEGF antibody compositions and methods
EP2265220A1 (en) 2008-03-05 2010-12-29 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
JP2011516585A (ja) * 2008-04-15 2011-05-26 イマネンス・インテグラル・デルモ・コレクション・インコーポレーテッド スキンケア組成物およびその使用方法
EP2323679A4 (en) 2008-07-25 2012-08-22 Univ Colorado CLIP INHIBITORS AND METHODS FOR MODULATING IMMUNE FUNCTION
WO2010083051A2 (en) * 2009-01-15 2010-07-22 ProChon Biotech, Ltd. Cartilage particle tissue mixtures optionally combined with a cancellous construct
CN101891811B (zh) * 2010-05-28 2011-11-09 暨南大学 一种鲨鱼血管生成抑制因子及其生产纯化方法和应用
CN101899104B (zh) * 2010-05-28 2012-04-18 暨南大学 一种鲨鱼软骨血管生成抑制因子小分子多肽及其生产纯化方法和应用
RU2592850C2 (ru) * 2011-01-19 2016-07-27 Хиросаки Юниверсити Способ крупномасштабного получения протеогликана
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CN104894200B (zh) * 2015-05-12 2020-10-30 浙江海洋学院 路氏双髻鲨软骨血管生成抑制因子的制备方法
KR101628982B1 (ko) 2015-11-27 2016-06-09 김준혁 항종양 및 면역 증강용 건강식품 조성물
US10786471B2 (en) 2017-02-06 2020-09-29 Massachusetts Institute Of Technology Methods and products related to glutaminase inhibitors
CN109394786A (zh) * 2018-10-26 2019-03-01 西交利物浦大学 一种抗肿瘤的药物组合物
WO2020203812A1 (ja) * 2019-03-29 2020-10-08 学校法人慶應義塾 魚介類由来成分による低酸素応答制御
WO2020251412A2 (ru) * 2019-06-14 2020-12-17 Общество С Ограниченной Ответственностью "Айтупайф" (Ооо "Айтулайф") Способ получения йодированных белков с детерминированным содержанием йода
CN112986499A (zh) * 2021-02-26 2021-06-18 山西奥瑞生物材料有限公司 一种同种骨植入材料残余水量均匀度测定方法

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US4042457A (en) * 1975-11-10 1977-08-16 Rush-Presbyterian-St. Luke's Medical Center Preparation of tissue invasion inhibitor and method of treatment utilizing the inhibitor
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Also Published As

Publication number Publication date
CN1153477A (zh) 1997-07-02
CZ290520B6 (cs) 2002-08-14
DK0759765T3 (da) 2003-01-27
DE69528258D1 (de) 2002-10-24
SI0759765T1 (en) 2003-02-28
RU2156132C2 (ru) 2000-09-20
NO964547D0 (no) 1996-10-25
EP0759765A1 (en) 1997-03-05
US5985839A (en) 1999-11-16
FI117375B (fi) 2006-09-29
AU719118B2 (en) 2000-05-04
KR100378787B1 (ko) 2003-06-19
US5618925A (en) 1997-04-08
WO1995032722A1 (en) 1995-12-07
CN1147305C (zh) 2004-04-28
NO317674B1 (no) 2004-11-29
AU2300195A (en) 1995-12-21
CA2188793C (en) 2001-01-16
NZ284407A (en) 1998-04-27
ES2182900T3 (es) 2003-03-16
BG62954B1 (bg) 2000-12-29
FI964327A7 (fi) 1996-12-20
BG100941A (en) 1997-07-31
ATE224198T1 (de) 2002-10-15
RO114868B1 (ro) 1999-08-30
PT759765E (pt) 2003-02-28
CZ314196A3 (en) 1997-04-16
CN1541656A (zh) 2004-11-03
PL317076A1 (en) 1997-03-03
DE69528258T2 (de) 2003-04-17
FI964327A0 (fi) 1996-10-28
NO964547L (no) 1996-12-30
PL181981B1 (en) 2001-10-31
EP0759765B1 (en) 2002-09-18
BR9507552A (pt) 1997-08-05
HUT76554A (en) 1997-09-29
CA2188793A1 (en) 1995-12-07
HU220784B1 (hu) 2002-05-28
KR970702729A (ko) 1997-06-10
JPH09512563A (ja) 1997-12-16
IS4379A (is) 1996-10-25
HU9602975D0 (en) 1997-01-28

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