IS3721A7 - Viðskeytt benzimidazole, aðferð við lögun þeirra og lyfjafræðileg notkun - Google Patents

Viðskeytt benzimidazole, aðferð við lögun þeirra og lyfjafræðileg notkun

Info

Publication number
IS3721A7
IS3721A7 IS3721A IS3721A IS3721A7 IS 3721 A7 IS3721 A7 IS 3721A7 IS 3721 A IS3721 A IS 3721A IS 3721 A IS3721 A IS 3721A IS 3721 A7 IS3721 A7 IS 3721A7
Authority
IS
Iceland
Prior art keywords
benzimidazole
addition
pharmacological use
pharmacological
Prior art date
Application number
IS3721A
Other languages
English (en)
Icelandic (is)
Inventor
Elof Brändström Arne
Lennart Lindberg Per
Elisabeth Sundén Gunnel
Original Assignee
Aktiebolaget Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aktiebolaget Astra filed Critical Aktiebolaget Astra
Publication of IS3721A7 publication Critical patent/IS3721A7/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
IS3721A 1990-06-20 1991-06-20 Viðskeytt benzimidazole, aðferð við lögun þeirra og lyfjafræðileg notkun IS3721A7 (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9002206A SE9002206D0 (sv) 1990-06-20 1990-06-20 New compounds

Publications (1)

Publication Number Publication Date
IS3721A7 true IS3721A7 (is) 1991-12-21

Family

ID=20379831

Family Applications (1)

Application Number Title Priority Date Filing Date
IS3721A IS3721A7 (is) 1990-06-20 1991-06-20 Viðskeytt benzimidazole, aðferð við lögun þeirra og lyfjafræðileg notkun

Country Status (27)

Country Link
EP (1) EP0535081A1 (no)
JP (1) JPH05507713A (no)
CN (1) CN1058212A (no)
AP (1) AP215A (no)
AU (1) AU649453B2 (no)
BG (1) BG97200A (no)
CA (1) CA2083714A1 (no)
CZ (1) CZ279772B6 (no)
FI (1) FI925766A0 (no)
HU (1) HUT62881A (no)
IE (1) IE912025A1 (no)
IL (1) IL98470A0 (no)
IS (1) IS3721A7 (no)
LT (2) LT3977B (no)
LV (1) LV10953A (no)
MA (1) MA22199A1 (no)
NO (1) NO924775D0 (no)
NZ (1) NZ238546A (no)
OA (1) OA09682A (no)
PT (1) PT98035A (no)
RO (1) RO110493B1 (no)
SE (1) SE9002206D0 (no)
TN (1) TNSN91049A1 (no)
TW (1) TW216418B (no)
WO (1) WO1991019711A1 (no)
YU (1) YU104191A (no)
ZA (2) ZA914297B (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
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SE9002043D0 (sv) * 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
IS4232A (is) * 1993-12-06 1995-06-07 Astra Aktiebolag Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
JP2003523386A (ja) 2000-02-24 2003-08-05 コプラン・リサーチ・ラボラトリーズ・リミテッド 経口投与可能な酸安定性の抗潰瘍性ベンゾイミダゾール誘導体
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
JP4732696B2 (ja) 2002-04-09 2011-07-27 フラメル・テクノロジー 活性成分の改変された放出のための、マイクロカプセルの水性懸濁液形態での経口医薬品製剤
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
KR20060092255A (ko) 2003-09-26 2006-08-22 알자 코포레이션 고도의 약물적재를 제공하는 약물코팅제 및 그의 제조방법
TW200606163A (en) 2004-04-22 2006-02-16 Eisai Co Ltd Imidazopyridine compound
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US20070015782A1 (en) * 2005-04-15 2007-01-18 Eisai Co., Ltd. Benzimidazole compound
US9040564B2 (en) 2005-04-28 2015-05-26 Eisai R&D Management Co., Ltd. Stabilized composition
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
WO2007122686A1 (ja) * 2006-04-14 2007-11-01 Eisai R & D Management Co., Ltd. ベンズイミダゾール化合物
EP2046334B1 (en) 2006-07-25 2014-05-21 Vecta Ltd. Compositions and meth0ds for inhibiting gastric acide secretion using derivatives of small dicarboxylic acids in combination with ppi
EP2065379A4 (en) * 2006-10-13 2011-01-19 Eisai R&D Man Co Ltd BENZIMIDAZOLE HAVING INHIBITORY ACTIVITY OF GASTRIC ACID SECRETION
KR20110079641A (ko) 2008-09-09 2011-07-07 아스트라제네카 아베 제약 조성물을 이를 필요로 하는 환자에게 전달하는 방법
MX2011013467A (es) 2009-06-25 2012-02-13 Astrazeneca Ab Metodo para tratar un paciente que corre el riesgo de desarollar una ulcera asociada a antiinflamatorio no esteroide (aine).
WO2011080500A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
US20120294937A1 (en) 2009-12-29 2012-11-22 Novartis Ag New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080502A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
EP2601947A1 (en) 2011-12-05 2013-06-12 Abo Bakr Mohammed Ali Al-Mehdar Fixed-dose combination for treatment of helicobacter pylori associated diseases
US9539214B2 (en) 2011-12-28 2017-01-10 Pozen Inc. Compositions and methods for delivery of omeprazole plus acetylsalicylic acid
EP4289425A3 (en) * 2016-09-14 2024-08-07 Yufeng Jane Tseng Novel substituted benzimidazole derivatives as d-amino acid oxidase (daao) inhibitors

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (no) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8300736D0 (sv) 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
SE8301182D0 (sv) 1983-03-04 1983-03-04 Haessle Ab Novel compounds
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US4738975A (en) 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
NZ234564A (en) 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
KR890701580A (ko) * 1987-10-30 1989-12-21 앤더스 베딘 골(骨)손실에 관련된 질병 치료용 2-피리디닐메틸(술피닐 또는 티오) 벤즈이미다졸
JPH03501609A (ja) * 1987-12-11 1991-04-11 ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング 新規ベンゾイミダゾール誘導体
JPH03504497A (ja) * 1988-05-25 1991-10-03 ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング 新規フルオルアルコキシ化合物

Also Published As

Publication number Publication date
AP215A (en) 1992-09-02
LV10953A (lv) 1995-12-20
IL98470A0 (en) 1992-07-15
ZA914296B (en) 1992-03-25
NO924775L (no) 1992-12-10
EP0535081A1 (en) 1993-04-07
LT3977B (en) 1996-06-25
LTIP1713A (en) 1995-08-25
WO1991019711A1 (en) 1991-12-26
IE912025A1 (en) 1992-01-01
SE9002206D0 (sv) 1990-06-20
MA22199A1 (fr) 1992-04-01
AU649453B2 (en) 1994-05-26
PT98035A (pt) 1992-03-31
JPH05507713A (ja) 1993-11-04
CZ279772B6 (cs) 1995-06-14
YU104191A (sh) 1994-01-20
FI925766A7 (fi) 1992-12-18
TW216418B (no) 1993-11-21
LT3952B (en) 1996-05-27
OA09682A (en) 1993-05-15
NO924775D0 (no) 1992-12-10
CS189491A3 (en) 1992-04-15
FI925766A0 (fi) 1992-12-18
HU9204033D0 (en) 1993-03-29
HUT62881A (en) 1993-06-28
TNSN91049A1 (fr) 1992-10-25
ZA914297B (en) 1992-03-25
NZ238546A (en) 1994-03-25
CN1058212A (zh) 1992-01-29
AP9100285A0 (en) 1991-07-31
BG97200A (bg) 1993-12-24
AU8009791A (en) 1992-01-07
RO110493B1 (ro) 1996-01-30
LTIP1712A (en) 1995-08-25
CA2083714A1 (en) 1991-12-21

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