IS3660A7 - Læknisfræðilega virk klóró-súbstitúreuð bensimidazole, aðferð við framleiðslu þeirra og notkun - Google Patents

Læknisfræðilega virk klóró-súbstitúreuð bensimidazole, aðferð við framleiðslu þeirra og notkun

Info

Publication number
IS3660A7
IS3660A7 IS3660A IS3660A IS3660A7 IS 3660 A7 IS3660 A7 IS 3660A7 IS 3660 A IS3660 A IS 3660A IS 3660 A IS3660 A IS 3660A IS 3660 A7 IS3660 A7 IS 3660A7
Authority
IS
Iceland
Prior art keywords
manufacture
substituted benzimidazole
medically active
active chloro
chloro
Prior art date
Application number
IS3660A
Other languages
English (en)
Inventor
Elof Brändström Arne
Lennart Lindberg Per
Ingemar Starke Carl
Elisabeth Sundén Gunnel
Original Assignee
Aktiebolaget Hässle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aktiebolaget Hässle filed Critical Aktiebolaget Hässle
Publication of IS3660A7 publication Critical patent/IS3660A7/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS3660A 1989-12-20 1990-12-17 Læknisfræðilega virk klóró-súbstitúreuð bensimidazole, aðferð við framleiðslu þeirra og notkun IS3660A7 (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/454,049 US4965269A (en) 1989-12-20 1989-12-20 Therapeutically active chloro substituted benzimidazoles

Publications (1)

Publication Number Publication Date
IS3660A7 true IS3660A7 (is) 1991-06-21

Family

ID=23803085

Family Applications (1)

Application Number Title Priority Date Filing Date
IS3660A IS3660A7 (is) 1989-12-20 1990-12-17 Læknisfræðilega virk klóró-súbstitúreuð bensimidazole, aðferð við framleiðslu þeirra og notkun

Country Status (10)

Country Link
US (1) US4965269A (is)
CN (1) CN1052671A (is)
AU (1) AU6973991A (is)
IE (1) IE904249A1 (is)
IL (1) IL96398A0 (is)
IS (1) IS3660A7 (is)
PL (1) PL288336A1 (is)
PT (1) PT96257A (is)
WO (1) WO1991009029A1 (is)
ZA (1) ZA909141B (is)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
WO1991019712A1 (en) * 1990-06-20 1991-12-26 Aktiebolaget Astra Dialkoxy-pyridinyl-benzimidazole derivatives, process for their preparation and their pharmaceutical use
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
US6274591B1 (en) * 1997-11-03 2001-08-14 Joseph F. Foss Use of methylnaltrexone and related compounds
US6093734A (en) * 1998-08-10 2000-07-25 Partnership Of Michael E. Garst, George Sachs, And Jai Moo Shin Prodrugs of proton pump inhibitors
ES2192394T3 (es) 1998-08-10 2003-10-01 Winston Pharmateuticals Llc Profarmacos de inhibidores de la bomba de protones.
EP1437352A4 (en) * 2001-09-25 2004-12-08 Takeda Chemical Industries Ltd BENZIMIDAZOLE COMPOUND, METHOD FOR THE PRODUCTION AND USE THEREOF
EP1514870A4 (en) * 2002-06-14 2006-08-23 Takeda Pharmaceutical PRODRUG AND METHOD FOR THE PRODUCTION THEREOF
KR100788778B1 (ko) * 2002-07-19 2007-12-27 윈스턴 파마슈티컬즈, 엘엘씨 벤즈이미다졸 유도체 및 이들의 프로톤 펌프 억제제의프로드럭으로서의 이용
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
PL2368554T3 (pl) 2003-04-08 2015-05-29 Progenics Pharm Inc Preparaty farmaceutyczne zawierające metylonaltrekson
JP2006522817A (ja) * 2003-04-08 2006-10-05 プロジェニックス ファーマシューティカルズ，インコーポレーテッド 過敏性腸症候群を処置するための末梢オピオイドアンタゴニスト、特にメチルナルトレキソンの使用
MXPA05010821A (es) * 2003-04-08 2006-03-30 Progenics Pharm Inc Terapia de combinacion para constipacion que comprende un laxante y un antagonista opioide periferico.
WO2004112756A1 (en) 2003-06-26 2004-12-29 Isa Odidi Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
WO2005039640A1 (en) * 2003-10-03 2005-05-06 Allergan Inc. Compositions comprising trefoil factor family peptides and/or mucoadhesives and proton pump inhibitor prodrugs
US20050075371A1 (en) * 2003-10-03 2005-04-07 Allergan, Inc. Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
WO2005082337A2 (en) * 2004-02-18 2005-09-09 Allergan, Inc. Compositions comprising prodrugs of proton pump inhibitors
EP1715854A2 (en) * 2004-02-18 2006-11-02 Allergan, Inc. Prodrugs for the intravenous administration of proton pump inhibitors
CA2561700A1 (en) * 2004-04-16 2005-12-15 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and prokinetic agent
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
AU2006206454A1 (en) * 2005-01-20 2006-07-27 Progenics Pharmaceuticals, Inc. Use of methylnaltrexone and related compounds to treat post-operative gastrointestinal dysfunction
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
MX2007010833A (es) 2005-03-07 2009-02-17 Univ Chicago Uso de antagonistas opioides para atenuar proliferacion y migracion de células endoteliales.
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
US20080194611A1 (en) * 2005-06-03 2008-08-14 Alverdy John C Modulation of Cell Barrier Dysfunction
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
CN104825397A (zh) 2006-04-03 2015-08-12 伊萨·奥迪迪 含有机溶胶涂层的受控释放递送物件
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
WO2008036201A1 (en) * 2006-09-19 2008-03-27 Alevium Pharmaceuticals, Inc. Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
US20080103169A1 (en) 2006-10-27 2008-05-01 The Curators Of The University Of Missouri Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
JP5469593B2 (ja) 2007-03-29 2014-04-16 ワイス・エルエルシー 末梢性オピオイド受容体アンタゴニストおよびその使用
MX2009010550A (es) 2007-03-29 2009-12-14 Progenics Pharm Inc Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
WO2008121348A2 (en) 2007-03-29 2008-10-09 Progenics Pharmaceuticals, Inc. Peripheral opioid receptor antagonists and uses thereof
AU2008349873B2 (en) 2008-02-06 2014-02-13 Progenics Pharmaceuticals, Inc. Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone
JP2011512416A (ja) 2008-02-20 2011-04-21 ザ・キュレイターズ・オブ・ザ・ユニバーシティー・オブ・ミズーリ オメプラゾール及びランソプラゾールの組合せと緩衝剤を含んでなる組成物とそれを使用する方法
CA2719134C (en) 2008-03-21 2015-06-30 The University Of Chicago Treatment with opioid antagonists and mtor inhibitors
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (is) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8204879D0 (sv) * 1982-08-26 1982-08-26 Haessle Ab Novel chemical intermediates
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
GB2161160B (en) * 1984-07-06 1989-05-24 Fisons Plc Heterocyclic sulphinyl compounds
SE8404065D0 (sv) * 1984-08-10 1984-08-10 Haessle Ab Novel biologically active compounds
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
JPS62201884A (ja) * 1986-02-28 1987-09-05 Tokyo Tanabe Co Ltd ベンズイミダゾール誘導体及びその製造法
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
NZ234564A (en) * 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
JPS63183577A (ja) * 1987-01-23 1988-07-28 Grelan Pharmaceut Co Ltd ベンズイミダゾ−ル誘導体
US4839365A (en) * 1987-05-19 1989-06-13 Shinogi & Co., Ltd. Thienopyridine derivatives useful in treating gastric ulcers
FI96860C (fi) * 1987-06-17 1996-09-10 Eisai Co Ltd Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi
JPH03501609A (ja) * 1987-12-11 1991-04-11 ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング 新規ベンゾイミダゾール誘導体

Also Published As

Publication number Publication date
PT96257A (pt) 1991-09-30
CN1052671A (zh) 1991-07-03
US4965269A (en) 1990-10-23
IL96398A0 (en) 1991-08-16
AU6973991A (en) 1991-07-18
WO1991009029A1 (en) 1991-06-27
IE904249A1 (en) 1991-07-03
PL288336A1 (en) 1991-12-02
ZA909141B (en) 1991-08-28

Similar Documents

Publication Publication Date Title
IS3721A7 (is) Viðskeytt benzimidazole, aðferð við lögun þeirra og lyfjafræðileg notkun
NO891380L (no) Anti-inflammatorisk hudfuktingspreparat og fremgangsmaate for fremstilling derav.
NO894296D0 (no) Fremgangsmaate for behandling av leddgikt og betennelsessykdommer.
IS3720A7 (is) Afleiður dialkoxy-pyridinyl-benzimidazole, aðferðvið lögun þeirra og lyfjafræðileg notkun
DE3865546D1 (de) Festkoerperszintillator und herstellungsverfahren.
NO903652L (no) Fremgangsmaate og anordning for kontinuerlig fremstilling av absorbente legemer.
DK360788A (da) Fremgangsmaade til fremstilling af ordnede kollagenstrukturer, isaer af human oprindelse, og de fremstillede, ordnede kollagenstrukturer
FI923548A7 (fi) Vaahtoa muodostava koostumus farmaseuttiseen käyttöön, sen käyttö ja h oitomenetelmä
IT8948426A0 (it) Derivati di acido 3-indolpiruvico, loro procedimento di produzione ed impiego terapeutico
NO164219C (no) Fremgangsmaate og anlegg for behandling av returnert boreslam.
NO884638L (no) Fremgangsmaate for fremstilling av terapeutisk aktive tetraliner, kromaner og beslektede forbindelser.
DK112885A (da) Medicinske plastre og fremstilling deraf
TR24895A (tr) PIRIMIDIN TüREVLERI,BUNLARIN ISTIHSAL EDILMESI VE KULLANILMASI
IT9019791A0 (it) Struttura di scocca,procedimento ed apparecchio per la sua produzione
FI913036A7 (fi) Terapeuttisesti aktiivinen substituoitu bentsimidatsoli ja menetelmä s en valmistamiseksi
IS3632A7 (is) Benzodíazepín, aðferð og milliefni við framleiðslu þeirra, og notkun þeirra við lækningar
IT9067363A0 (it) Composti polifluoroalchilici azotati, procedimento per la loro preparazione e loro impiego
IS3658A7 (is) Læknisfræðilega virk flúró-súbstitúeruð benzimidazole, aðferð við framleiðslu þeirra og notkun
IT8720982A0 (it) P-amminofenoli loro derivati emetodo di utilizzazione.
IT8822389A0 (it) Isopolipeptidi e procedimento per la loro preparazione
NO905543L (no) Fremgangsmaate for fremstilling og anvendelse av aminopyridinylmetanoler og aminometylpyridinaminer.
IS3531A7 (is) Læknisfræðilega virkt súbstitúerað benzimidazole og aðferð við framleiðslu þess
IT8803670A0 (it) Procedimento per la realizzazione di granuli, in particolare granuli sferoidali, ed apparecchiatura per l'attuazione di tale metodo
FI896159A0 (fi) Valsanordning med en undervals med hydrauliskt innerstoed.
IS3530A7 (is) Nýtt læknisfræðilega virkt efni og aðferð við framleiðslu þess