IS5469A - Aðferð til efnasmíða á pýrról amíðum - Google Patents

Aðferð til efnasmíða á pýrról amíðum

Info

Publication number: IS5469A
Authority: IS; Iceland
Prior art keywords: synthesis; reaction; followed; pyrrole amides; pyrrole
Prior art date: 1997-11-13

Application number

IS5469A

Other languages

English (en)

Inventor

Anthony Ragan John

Woodall Makowski Teresa

Jon Am Enda David

Jane Clifford Pamela

Randall Young Gregory

Kay Conrad Alyson

Allen Eisenbeis Shane

John Meldrum Allen Douglas

Joseph Quallich George

Original Assignee

Pfizer Products Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-13

Filing date

2000-04-26

Publication date

2000-04-26

2000-04-26 Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.

2000-04-26 Publication of IS5469A publication Critical patent/IS5469A/is

Links

238000000034 method Methods 0.000 title abstract 2
KAESVJOAVNADME-UHFFFAOYSA-N 1H-pyrrole Natural products C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
-1 pyrrole amides Chemical class 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
NHNHWBFFDARHFO-UHFFFAOYSA-N 2-(1h-pyrrol-2-yl)acetamide Chemical class NC(=O)CC1=CC=CN1 NHNHWBFFDARHFO-UHFFFAOYSA-N 0.000 abstract 1
RGHQKFQZGLKBCF-UHFFFAOYSA-N 2-bromoethyl acetate Chemical compound CC(=O)OCCBr RGHQKFQZGLKBCF-UHFFFAOYSA-N 0.000 abstract 1
102000027484 GABAA receptors Human genes 0.000 abstract 1
108091008681 GABAA receptors Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000004982 aromatic amines Chemical class 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Furan Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Tea And Coffee (AREA)
Fats And Perfumes (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)

IS5469A 1997-11-13 2000-04-26 Aðferð til efnasmíða á pýrról amíðum IS5469A (is)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US6542297P	1997-11-13	1997-11-13
US7426698P	1998-02-10	1998-02-10
PCT/IB1998/001672 WO1999025684A1 (en)	1997-11-13	1998-10-21	Method of synthesis of pyrrole amides

Publications (1)

Publication Number	Publication Date
IS5469A true IS5469A (is)	2000-04-26

Family

ID=26745584

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5469A IS5469A (is)	1997-11-13	2000-04-26	Aðferð til efnasmíða á pýrról amíðum

Country Status (35)

Country	Link
US (1)	US6262272B1 (is)
EP (1)	EP1030838B1 (is)
JP (1)	JP3497469B2 (is)
KR (1)	KR100386722B1 (is)
CN (2)	CN1280566A (is)
AT (1)	ATE231492T1 (is)
AU (1)	AU745788B2 (is)
BG (1)	BG64530B1 (is)
BR (1)	BR9814161A (is)
CA (1)	CA2310095A1 (is)
CZ (1)	CZ20001769A3 (is)
DE (1)	DE69810959T2 (is)
DK (1)	DK1030838T3 (is)
DZ (1)	DZ2651A1 (is)
EA (1)	EA002243B1 (is)
ES (1)	ES2186232T3 (is)
HR (1)	HRP20000298A2 (is)
HU (1)	HUP0100235A3 (is)
ID (1)	ID24135A (is)
IL (1)	IL135710A0 (is)
IS (1)	IS5469A (is)
MA (1)	MA24697A1 (is)
NO (1)	NO20002214L (is)
NZ (1)	NZ503916A (is)
OA (1)	OA11378A (is)
PA (1)	PA8462901A1 (is)
PL (1)	PL340554A1 (is)
PT (1)	PT1030838E (is)
SK (1)	SK6872000A3 (is)
TN (1)	TNSN98204A1 (is)
TR (1)	TR200001343T2 (is)
TW (1)	TW509675B (is)
UY (1)	UY25249A1 (is)
WO (1)	WO1999025684A1 (is)
YU (1)	YU27300A (is)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2381553A1 (en) *	1999-08-31	2001-03-08	Neurogen Corporation	Fused pyrrolecarboxamides: gaba brain receptor ligands
CA2419966A1 (en) *	2000-09-06	2002-03-14	Neurogen Corporation	Aryl substituted tetrahydroindazoles and their use as ligands for the gaba-a receptor
MXPA03004939A (es) *	2000-12-04	2003-09-10	Pfizer Prod Inc	Sintesis de pirrolamidas.
US6852730B2 (en)	2002-02-07	2005-02-08	Neurogen Corporation	Substituted fused pyrazolecarboxylic acid arylamides and related compounds
US20080153629A1 (en) *	2004-05-07	2008-06-26	Sullivan Michael J	Thick Outer Cover Layer Golf Ball
CN102786458B (zh) *	2012-06-04	2014-02-12	天津渤海职业技术学院	吡咯甲酰胺衍生物、其制备方法和用途
WO2015112754A1 (en) *	2014-01-24	2015-07-30	Abbvie Inc.	Furo-3-carboxamide derivatives and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5750702A (en)	1993-10-27	1998-05-12	Neurogen Corporation	Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands
US5484944A (en)	1993-10-27	1996-01-16	Neurogen Corporation	Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands
US5804686A (en) *	1996-01-19	1998-09-08	Neurogen Corporation	fused pyrrolecarboxamides; a new class of GABA brain receptor ligands
AU2218997A (en)	1996-03-22	1997-10-10	Neurogen Corporation	Certain fused pyrrolecarboxamides as gaba brain receptor ligands

1998
- 1998-10-21 EP EP98946678A patent/EP1030838B1/en not_active Expired - Lifetime
- 1998-10-21 ID IDW20000893A patent/ID24135A/id unknown
- 1998-10-21 PT PT98946678T patent/PT1030838E/pt unknown
- 1998-10-21 HU HU0100235A patent/HUP0100235A3/hu unknown
- 1998-10-21 CN CN98811119A patent/CN1280566A/zh active Pending
- 1998-10-21 JP JP2000521068A patent/JP3497469B2/ja not_active Expired - Fee Related
- 1998-10-21 CN CNA031594727A patent/CN1508129A/zh active Pending
- 1998-10-21 PL PL98340554A patent/PL340554A1/xx not_active Application Discontinuation
- 1998-10-21 CA CA002310095A patent/CA2310095A1/en not_active Abandoned
- 1998-10-21 SK SK687-2000A patent/SK6872000A3/sk unknown
- 1998-10-21 ES ES98946678T patent/ES2186232T3/es not_active Expired - Lifetime
- 1998-10-21 CZ CZ20001769A patent/CZ20001769A3/cs unknown
- 1998-10-21 TR TR2000/01343T patent/TR200001343T2/xx unknown
- 1998-10-21 IL IL13571098A patent/IL135710A0/xx unknown
- 1998-10-21 BR BR9814161-9A patent/BR9814161A/pt not_active Application Discontinuation
- 1998-10-21 NZ NZ503916A patent/NZ503916A/xx unknown
- 1998-10-21 KR KR10-2000-7005185A patent/KR100386722B1/ko not_active Expired - Fee Related
- 1998-10-21 HR HR20000298A patent/HRP20000298A2/hr not_active Application Discontinuation
- 1998-10-21 DK DK98946678T patent/DK1030838T3/da active
- 1998-10-21 US US09/403,985 patent/US6262272B1/en not_active Expired - Fee Related
- 1998-10-21 WO PCT/IB1998/001672 patent/WO1999025684A1/en not_active Ceased
- 1998-10-21 AT AT98946678T patent/ATE231492T1/de not_active IP Right Cessation
- 1998-10-21 YU YU27300A patent/YU27300A/sh unknown
- 1998-10-21 AU AU93639/98A patent/AU745788B2/en not_active Ceased
- 1998-10-21 DE DE69810959T patent/DE69810959T2/de not_active Expired - Fee Related
- 1998-10-21 EA EA200000413A patent/EA002243B1/ru not_active IP Right Cessation
- 1998-11-10 PA PA19988462901A patent/PA8462901A1/es unknown
- 1998-11-10 TW TW087118708A patent/TW509675B/zh not_active IP Right Cessation
- 1998-11-11 DZ DZ980261A patent/DZ2651A1/xx active
- 1998-11-11 TN TNTNSN98204A patent/TNSN98204A1/fr unknown
- 1998-11-11 MA MA25342A patent/MA24697A1/fr unknown
- 1998-11-13 UY UY25249A patent/UY25249A1/es not_active IP Right Cessation
2000
- 2000-04-26 IS IS5469A patent/IS5469A/is unknown
- 2000-04-28 NO NO20002214A patent/NO20002214L/no unknown
- 2000-05-09 BG BG104413A patent/BG64530B1/bg unknown
- 2000-05-12 OA OA1200000136A patent/OA11378A/en unknown

Also Published As

Publication number	Publication date
BG64530B1 (bg)	2005-06-30
EP1030838B1 (en)	2003-01-22
AU9363998A (en)	1999-06-07
HUP0100235A3 (en)	2002-04-29
JP2001523660A (ja)	2001-11-27
KR100386722B1 (ko)	2003-06-09
YU27300A (sh)	2002-10-18
PA8462901A1 (es)	2000-05-24
TW509675B (en)	2002-11-11
OA11378A (en)	2004-01-27
ES2186232T3 (es)	2003-05-01
KR20010032063A (ko)	2001-04-16
HRP20000298A2 (en)	2001-02-28
AU745788B2 (en)	2002-03-28
SK6872000A3 (en)	2002-02-05
ATE231492T1 (de)	2003-02-15
CN1508129A (zh)	2004-06-30
BG104413A (en)	2001-02-28
BR9814161A (pt)	2000-09-26
NZ503916A (en)	2002-08-28
DE69810959T2 (de)	2003-06-05
UY25249A1 (es)	1999-07-19
EA002243B1 (ru)	2002-02-28
EP1030838A1 (en)	2000-08-30
CA2310095A1 (en)	1999-05-27
MA24697A1 (fr)	1999-07-01
DZ2651A1 (fr)	2003-03-15
HUP0100235A2 (hu)	2001-12-28
US6262272B1 (en)	2001-07-17
JP3497469B2 (ja)	2004-02-16
PT1030838E (pt)	2003-03-31
TR200001343T2 (tr)	2001-02-21
WO1999025684A1 (en)	1999-05-27
PL340554A1 (en)	2001-02-12
NO20002214L (no)	2000-05-12
DK1030838T3 (da)	2003-02-24
ID24135A (id)	2000-07-06
EA200000413A1 (ru)	2000-12-25
IL135710A0 (en)	2001-05-20
CN1280566A (zh)	2001-01-17
CZ20001769A3 (cs)	2001-09-12
TNSN98204A1 (fr)	2005-03-15
DE69810959D1 (de)	2003-02-27
NO20002214D0 (no)	2000-04-28

Publication	Publication Date	Title
DK0861223T3 (da)	2004-04-05	Fremgangsmåde til syntese af curcumin-relaterede forbindelser
CY1109384T1 (el)	2014-07-02	Συνθεση εστερων ενωμενων με ημιση αλκυλιου μακρας αλυσσιδας
DK1627880T3 (da)	2008-12-08	Boronester og -syreforbindelser samt syntese og anvendelser
ES8701723A1 (es)	1986-12-01	Procedimiento para preparar 2,2,6,6-tetraalquil-4-piperidilaminas
BR9306401A (pt)	1995-07-11	Processo para a preparação de aminas aromáticas substituídas
IS5469A (is)	2000-04-26	Aðferð til efnasmíða á pýrról amíðum
ATE356815T1 (de)	2007-04-15	Herstellung von perylen-3,4-dicarbonsäure- anhydriden
BR9007042A (pt)	1991-11-12	Processo e catalisador para a preparacao de 2,2'bipiridilas
TR200000452T2 (tr)	2000-07-21	Aromatik aminler üretilmesine yönelik işlem.
ATE253026T1 (de)	2003-11-15	Verfahren zur oligomerisierung von c6-olefinen
FI854624A7 (fi)	1986-05-30	Syaanivedyn reaktiotuotteiden valmistusmenetelmä.
DK0924195T3 (da)	2004-01-19	Fremgangsmåde til fremstilling af aminocyanacetamid
ATE11401T1 (de)	1985-02-15	Substituierte biphenyl-2-carboxaldehyde und verfahren zu ihrer herstellung.
DK0971907T3 (da)	2002-06-10	Fremgangsmåde til fremstilling af 1,3-disubstituerede 2-nitroguanidiner
DK0934256T3 (da)	2002-12-02	Fremgangsmåde til fremstilling af cyanocinnamamider
BR0115874A (pt)	2003-10-28	Sìntese de pirrole-amidas
BR9909570A (pt)	2004-06-01	Processo altamente seletivo, produto preparado pelo mesmo, e, processo para preparar uma quinonaimina a partir de uma hidroxifenilamina correspondente
DK1044204T3 (da)	2003-09-29	Fremgangsmåde til fremstiling af alfa-oxolactamer
KR900009541A (ko)	1990-07-04	호프만 전이반응에 의한 아민의 제조방법
ES2130992A1 (es)	1999-07-01	Procedimiento para la preparacion de 1,4-dihalofenacinas e intermedios de sintesis.
ES545535A0 (es)	1986-01-16	Un procedimiento para preparar derivados de 3-cianoazetidinasustituidos en n
ECSP982743A (es)	1999-04-16	Procedimientos de sintesis de pirrol amidas
ES1044171U (es)	2000-03-01	Aparato para fijacion de alambres ondulados.