DZ2651A1 - Nouveaux pyrrole-amides et leur procédé de production. - Google Patents

Nouveaux pyrrole-amides et leur procédé de production.

Info

Publication number: DZ2651A1
Authority: DZ; Algeria
Prior art keywords: amides; production process; reaction; new pyrrole; followed
Prior art date: 1997-11-13

Application number

DZ980261A

Other languages

English (en)

Inventor

John Anthony Ragan

Teresa Woodall Makowski

David John Am Ende

Pamela Jane Clifford

Gregory Randall Young

Alyson Kay Conrad

Shane Allen Eisenbeis

Douglas John Meldrum Allen

George Joseph Quallich

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-13

Filing date

1998-11-11

Publication date

2003-03-15

1998-11-11 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2003-03-15 Application granted granted Critical

2003-03-15 Publication of DZ2651A1 publication Critical patent/DZ2651A1/fr

Links

RLOQBKJCOAXOLR-UHFFFAOYSA-N 1h-pyrrole-2-carboxamide Chemical class NC(=O)C1=CC=CN1 RLOQBKJCOAXOLR-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
NHNHWBFFDARHFO-UHFFFAOYSA-N 2-(1h-pyrrol-2-yl)acetamide Chemical class NC(=O)CC1=CC=CN1 NHNHWBFFDARHFO-UHFFFAOYSA-N 0.000 abstract 1
RGHQKFQZGLKBCF-UHFFFAOYSA-N 2-bromoethyl acetate Chemical compound CC(=O)OCCBr RGHQKFQZGLKBCF-UHFFFAOYSA-N 0.000 abstract 1
102000027484 GABAA receptors Human genes 0.000 abstract 1
108091008681 GABAA receptors Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000004982 aromatic amines Chemical class 0.000 abstract 1
150000004820 halides Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Tea And Coffee (AREA)
Fats And Perfumes (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)

DZ980261A 1997-11-13 1998-11-11 Nouveaux pyrrole-amides et leur procédé de production. DZ2651A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US6542297P	1997-11-13	1997-11-13
US7426698P	1998-02-10	1998-02-10

Publications (1)

Publication Number	Publication Date
DZ2651A1 true DZ2651A1 (fr)	2003-03-15

Family

ID=26745584

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ980261A DZ2651A1 (fr)	1997-11-13	1998-11-11	Nouveaux pyrrole-amides et leur procédé de production.

Country Status (35)

Country	Link
US (1)	US6262272B1 (fr)
EP (1)	EP1030838B1 (fr)
JP (1)	JP3497469B2 (fr)
KR (1)	KR100386722B1 (fr)
CN (2)	CN1508129A (fr)
AT (1)	ATE231492T1 (fr)
AU (1)	AU745788B2 (fr)
BG (1)	BG64530B1 (fr)
BR (1)	BR9814161A (fr)
CA (1)	CA2310095A1 (fr)
CZ (1)	CZ20001769A3 (fr)
DE (1)	DE69810959T2 (fr)
DK (1)	DK1030838T3 (fr)
DZ (1)	DZ2651A1 (fr)
EA (1)	EA002243B1 (fr)
ES (1)	ES2186232T3 (fr)
HR (1)	HRP20000298A2 (fr)
HU (1)	HUP0100235A3 (fr)
ID (1)	ID24135A (fr)
IL (1)	IL135710A0 (fr)
IS (1)	IS5469A (fr)
MA (1)	MA24697A1 (fr)
NO (1)	NO20002214L (fr)
NZ (1)	NZ503916A (fr)
OA (1)	OA11378A (fr)
PA (1)	PA8462901A1 (fr)
PL (1)	PL340554A1 (fr)
PT (1)	PT1030838E (fr)
SK (1)	SK6872000A3 (fr)
TN (1)	TNSN98204A1 (fr)
TR (1)	TR200001343T2 (fr)
TW (1)	TW509675B (fr)
UY (1)	UY25249A1 (fr)
WO (1)	WO1999025684A1 (fr)
YU (1)	YU27300A (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUP0202534A3 (en) *	1999-08-31	2002-12-28	Neurogen Corp Branford	Fused pyrrolecarboxamides: gaba brain receptor ligands and pharmaceutical compositions containing them
WO2002020492A1 (fr) *	2000-09-06	2002-03-14	Neurogen Corporation	Tetrahydroindazoles substitues par aryle et leur utilisation comme ligands pour le recepteur de gaba-a
BR0115874A (pt) *	2000-12-04	2003-10-28	Pfizer Prod Inc	Sìntese de pirrole-amidas
AU2003212979A1 (en)	2002-02-07	2003-09-02	Neurogen Corporation	Substituted fused pyrazolecarboxylic acid arylamides and related compounds
US20080153629A1 (en) *	2004-05-07	2008-06-26	Sullivan Michael J	Thick Outer Cover Layer Golf Ball
CN102786458B (zh) *	2012-06-04	2014-02-12	天津渤海职业技术学院	吡咯甲酰胺衍生物、其制备方法和用途
EP3097095A1 (fr) *	2014-01-24	2016-11-30	AbbVie Inc.	Dérivés furo-3-carboxamide et méthodes d'utilisation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5750702A (en)	1993-10-27	1998-05-12	Neurogen Corporation	Certain pyrrolo pyridine-3-carboxamides; a new class of GABA brain receptor ligands
US5484944A (en) *	1993-10-27	1996-01-16	Neurogen Corporation	Certain fused pyrrolecarboxanilides and their use as GABA brain receptor ligands
US5804686A (en)	1996-01-19	1998-09-08	Neurogen Corporation	fused pyrrolecarboxamides; a new class of GABA brain receptor ligands
WO1997034870A1 (fr)	1996-03-22	1997-09-25	Neurogen Corporation	Certains pyrrolecarboxamides fusionnes utilises comme ligands de recepteurs cerebraux gaba

1998
- 1998-10-21 CN CNA031594727A patent/CN1508129A/zh active Pending
- 1998-10-21 EA EA200000413A patent/EA002243B1/ru not_active IP Right Cessation
- 1998-10-21 WO PCT/IB1998/001672 patent/WO1999025684A1/fr not_active Ceased
- 1998-10-21 EP EP98946678A patent/EP1030838B1/fr not_active Expired - Lifetime
- 1998-10-21 US US09/403,985 patent/US6262272B1/en not_active Expired - Fee Related
- 1998-10-21 DK DK98946678T patent/DK1030838T3/da active
- 1998-10-21 KR KR10-2000-7005185A patent/KR100386722B1/ko not_active Expired - Fee Related
- 1998-10-21 CA CA002310095A patent/CA2310095A1/fr not_active Abandoned
- 1998-10-21 AT AT98946678T patent/ATE231492T1/de not_active IP Right Cessation
- 1998-10-21 ES ES98946678T patent/ES2186232T3/es not_active Expired - Lifetime
- 1998-10-21 JP JP2000521068A patent/JP3497469B2/ja not_active Expired - Fee Related
- 1998-10-21 CZ CZ20001769A patent/CZ20001769A3/cs unknown
- 1998-10-21 TR TR2000/01343T patent/TR200001343T2/xx unknown
- 1998-10-21 ID IDW20000893A patent/ID24135A/id unknown
- 1998-10-21 PT PT98946678T patent/PT1030838E/pt unknown
- 1998-10-21 HR HR20000298A patent/HRP20000298A2/hr not_active Application Discontinuation
- 1998-10-21 CN CN98811119A patent/CN1280566A/zh active Pending
- 1998-10-21 AU AU93639/98A patent/AU745788B2/en not_active Ceased
- 1998-10-21 SK SK687-2000A patent/SK6872000A3/sk unknown
- 1998-10-21 NZ NZ503916A patent/NZ503916A/xx unknown
- 1998-10-21 HU HU0100235A patent/HUP0100235A3/hu unknown
- 1998-10-21 IL IL13571098A patent/IL135710A0/xx unknown
- 1998-10-21 YU YU27300A patent/YU27300A/sh unknown
- 1998-10-21 DE DE69810959T patent/DE69810959T2/de not_active Expired - Fee Related
- 1998-10-21 PL PL98340554A patent/PL340554A1/xx not_active Application Discontinuation
- 1998-10-21 BR BR9814161-9A patent/BR9814161A/pt not_active Application Discontinuation
- 1998-11-10 PA PA19988462901A patent/PA8462901A1/es unknown
- 1998-11-10 TW TW087118708A patent/TW509675B/zh not_active IP Right Cessation
- 1998-11-11 DZ DZ980261A patent/DZ2651A1/fr active
- 1998-11-11 MA MA25342A patent/MA24697A1/fr unknown
- 1998-11-11 TN TNTNSN98204A patent/TNSN98204A1/fr unknown
- 1998-11-13 UY UY25249A patent/UY25249A1/es not_active IP Right Cessation
2000
- 2000-04-26 IS IS5469A patent/IS5469A/is unknown
- 2000-04-28 NO NO20002214A patent/NO20002214L/no unknown
- 2000-05-09 BG BG104413A patent/BG64530B1/bg unknown
- 2000-05-12 OA OA1200000136A patent/OA11378A/en unknown

Also Published As

Publication number	Publication date
CA2310095A1 (fr)	1999-05-27
OA11378A (en)	2004-01-27
WO1999025684A1 (fr)	1999-05-27
CN1508129A (zh)	2004-06-30
AU745788B2 (en)	2002-03-28
CN1280566A (zh)	2001-01-17
NZ503916A (en)	2002-08-28
EA200000413A1 (ru)	2000-12-25
HRP20000298A2 (en)	2001-02-28
EP1030838B1 (fr)	2003-01-22
IL135710A0 (en)	2001-05-20
JP2001523660A (ja)	2001-11-27
EA002243B1 (ru)	2002-02-28
YU27300A (sh)	2002-10-18
ID24135A (id)	2000-07-06
ES2186232T3 (es)	2003-05-01
BR9814161A (pt)	2000-09-26
PL340554A1 (en)	2001-02-12
TNSN98204A1 (fr)	2005-03-15
US6262272B1 (en)	2001-07-17
BG64530B1 (bg)	2005-06-30
DE69810959T2 (de)	2003-06-05
TW509675B (en)	2002-11-11
DK1030838T3 (da)	2003-02-24
NO20002214D0 (no)	2000-04-28
KR20010032063A (ko)	2001-04-16
UY25249A1 (es)	1999-07-19
PA8462901A1 (es)	2000-05-24
TR200001343T2 (tr)	2001-02-21
JP3497469B2 (ja)	2004-02-16
IS5469A (is)	2000-04-26
CZ20001769A3 (cs)	2001-09-12
HUP0100235A3 (en)	2002-04-29
EP1030838A1 (fr)	2000-08-30
MA24697A1 (fr)	1999-07-01
DE69810959D1 (de)	2003-02-27
NO20002214L (no)	2000-05-12
PT1030838E (pt)	2003-03-31
BG104413A (en)	2001-02-28
ATE231492T1 (de)	2003-02-15
SK6872000A3 (en)	2002-02-05
KR100386722B1 (ko)	2003-06-09
HUP0100235A2 (hu)	2001-12-28
AU9363998A (en)	1999-06-07

Publication	Publication Date	Title
RU94042224A (ru)	1996-07-20	Способ получения олигонуклеотидов и соответствующие промежуточные соединения
TR200000456T2 (tr)	2000-07-21	Glufosinatların ve ara ürünlerinin üretimine dair yöntem.
PT872481E (pt)	2009-05-20	Derivado de depsipéptido, processo para a sua produção, e novos intermediários do mesmo
FR2729663B1 (fr)	1998-02-13	Procede de production de composes polysulfures organiques
Hienzsch et al.	2013	Total synthesis of the hypermodified RNA bases wybutosine and hydroxywybutosine and their quantification together with other modified RNA bases in plant materials
ATE356815T1 (de)	2007-04-15	Herstellung von perylen-3,4-dicarbonsäure- anhydriden
NO20002214D0 (no)	2000-04-28	FremgangsmÕte for syntese av pyrrolaminer
DE60102008D1 (de)	2004-03-18	Herstellungsverfahren für ein bekanntes terazolderivat
EP1344772A4 (fr)	2005-03-16	Arylbis (perfluoroalkylsulfonyl) methane, son sel metallique et leurs procedes de production
HU9403256D0 (en)	1995-01-30	Process for producing 2'3'-di-dehydro-2'3'-dideoxynucleosides
DK0414262T3 (da)	1995-05-15	Fremgangsmåde til fremstilling af antikonvulsive cycliske aminosyreforbindelser
FI971311A0 (fi)	1997-03-27	Menetelmiä syklopropaanikarboksyylihapon ja sen johdosten valmistamiseksi
DK0543095T3 (da)	1999-09-13	Fremgangsmåde til fremstilling af 2-amino-6-halogenpurin og syntese af et mellemprodukt dertil
BE888562A (fr)	1981-08-17	Procede de production d'une preparation enzymatique de fructosyl-transferase,
Enders et al.	2004	A highly efficient asymmetric synthesis of homotaurine derivatives via diastereoselective ring-opening of γ-sultones
ATE11401T1 (de)	1985-02-15	Substituierte biphenyl-2-carboxaldehyde und verfahren zu ihrer herstellung.
EP0704460A4 (fr)	1996-07-10	Procede de production de polymere se terminant par un groupe fonctionnel eventuellement protege
FI863418A0 (fi)	1986-08-22	Foerfarande foer att bilda en aerosolstroem.
EP1043400A4 (fr)	2004-09-08	Procede de production de [s,s]-ethylenediamine-n,n'-acide disuccinique
EP0739885A4 (fr)	1997-04-16	Procede de production d'acide 3-isoxazolecarboxylique
EP0249136A3 (fr)	1988-04-06	Procédé de préparation d'urées cycliques
HU9802955D0 (en)	1999-02-01	Process for producing amino-cyano-acetamide
Enders et al.	2002	A short diastereo-and enantioselective synthesis of cis-4, 5-disubstituted oxazolidin-2-ones
FR2604447B1 (fr)	1989-05-19	Procede de production de l-threonine par fermentation
OA08098A (fr)	1987-03-31	Procédé de production de dérivés de 2-oxindole-1-carboxamide.