IS6250A - Streptomyces avermitilis gen sem stýra hlutfallinu á B2:B1 avermektínum - Google Patents

Streptomyces avermitilis gen sem stýra hlutfallinu á B2:B1 avermektínum

Info

Publication number
IS6250A
IS6250A IS6250A IS6250A IS6250A IS 6250 A IS6250 A IS 6250A IS 6250 A IS6250 A IS 6250A IS 6250 A IS6250 A IS 6250A IS 6250 A IS6250 A IS 6250A
Authority
IS
Iceland
Prior art keywords
avermectins
ratio
control
streptomyces avermitilis
avermitilis genes
Prior art date
Application number
IS6250A
Other languages
English (en)
Inventor
Jonelle Stutzman-Engwall Kim
Chen Yan
Gustafsson Claes
Krebber Anke
Stephen Minshull Jeremy
Ai Raillard Sun
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of IS6250A publication Critical patent/IS6250A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IS6250A 1999-08-12 2002-01-25 Streptomyces avermitilis gen sem stýra hlutfallinu á B2:B1 avermektínum IS6250A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14864599P 1999-08-12 1999-08-12
PCT/IB2000/001017 WO2001012821A1 (en) 1999-08-12 2000-07-24 Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins

Publications (1)

Publication Number Publication Date
IS6250A true IS6250A (is) 2002-01-25

Family

ID=22526696

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6250A IS6250A (is) 1999-08-12 2002-01-25 Streptomyces avermitilis gen sem stýra hlutfallinu á B2:B1 avermektínum

Country Status (39)

Country Link
US (3) US6632673B1 (is)
EP (1) EP1200606B1 (is)
JP (1) JP3884651B2 (is)
KR (1) KR100489856B1 (is)
CN (1) CN1186446C (is)
AP (1) AP2002002418A0 (is)
AR (1) AR022646A1 (is)
AT (1) ATE341632T1 (is)
AU (1) AU778837B2 (is)
BG (1) BG65902B1 (is)
BR (1) BRPI0013119B8 (is)
CA (1) CA2380872C (is)
CO (1) CO5290295A1 (is)
CY (1) CY1105778T1 (is)
CZ (1) CZ304402B6 (is)
DE (1) DE60031126T2 (is)
DK (1) DK1200606T3 (is)
EA (1) EA200200056A1 (is)
ES (1) ES2272299T3 (is)
GT (1) GT200000136A (is)
HK (1) HK1046710B (is)
HR (1) HRP20020130A2 (is)
HU (1) HU230600B1 (is)
IL (2) IL147563A0 (is)
IS (1) IS6250A (is)
MA (1) MA26813A1 (is)
MX (1) MXPA02001513A (is)
NO (1) NO20020664D0 (is)
NZ (1) NZ516517A (is)
OA (1) OA11998A (is)
PA (1) PA8499501A1 (is)
PE (1) PE20010690A1 (is)
PL (1) PL203818B1 (is)
PT (1) PT1200606E (is)
SK (1) SK288086B6 (is)
TN (1) TNSN00171A1 (is)
UY (1) UY26286A1 (is)
WO (1) WO2001012821A1 (is)
ZA (1) ZA200201072B (is)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ516517A (en) * 1999-08-12 2003-10-31 Pfizer Prod Inc Mutations in the aveC allele of Streptomyces avermitilis gene that reduce the ratio of cyclohexyl B2:cyclohexyl B1 avermectins
SI1476539T1 (sl) * 2002-02-12 2009-06-30 Pfizer Prod Inc Gen streptomyces avermitilis, ki uravnava razmerje B2:B1 avermektinov
US7943160B2 (en) * 2002-05-09 2011-05-17 Scimetrics Limited Corp. Pest control methods
US9493744B2 (en) * 2012-06-20 2016-11-15 Genentech, Inc. Methods for viral inactivation and other adventitious agents
KR102657859B1 (ko) 2021-04-07 2024-04-16 윤재식 일체형 내화 소켓

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5238848A (en) 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
US5525506A (en) 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
US5234831A (en) 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
IN167980B (is) * 1987-01-23 1991-01-19 Pfizer
US5240850A (en) 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
EP0313297B1 (en) 1987-10-23 1993-05-19 Pfizer Inc. Process for production of avermectin aglycones and cultures therefor
US5252474A (en) 1989-03-31 1993-10-12 Merck & Co., Inc. Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use
ES2079436T3 (es) 1989-03-31 1996-01-16 Merck & Co Inc Clonacion de genes de streptomyces avermitilis para biosintesis de avermectinas y procedimientos para su uso.
DK0711349T3 (da) 1993-07-30 2003-11-24 Pfizer Gener, der koder for forgrenet alfaketosyredehydrogenasekompleks fra Streptomyces avermitilis
FI942725A7 (fi) 1993-12-16 1995-06-17 Pfizer Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6096548A (en) 1996-03-25 2000-08-01 Maxygen, Inc. Method for directing evolution of a virus
EP0964922A4 (en) 1996-09-27 2000-10-25 Maxygen Inc METHOD FOR OPTIMIZING GENE THERAPY BY REPEATING SEQUENCE MIXING AND SELECTION
KR100568008B1 (ko) 1997-01-17 2006-04-07 맥시겐, 인크. 반복적 서열 재조합에 의한 전세포 및 유기체의 개량 방법
EP1690868A1 (en) 1997-10-31 2006-08-16 Maxygen, Inc. Modification of virus tropism and host range by viral genome shuffling
CA2320031A1 (en) * 1998-02-13 1999-08-19 Pfizer Products Inc. Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
US6248579B1 (en) * 1998-02-13 2001-06-19 Pfizer Inc Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins
NZ516517A (en) * 1999-08-12 2003-10-31 Pfizer Prod Inc Mutations in the aveC allele of Streptomyces avermitilis gene that reduce the ratio of cyclohexyl B2:cyclohexyl B1 avermectins

Also Published As

Publication number Publication date
CO5290295A1 (es) 2003-06-27
HK1046710B (zh) 2005-05-13
US20030232415A1 (en) 2003-12-18
EA200200056A1 (ru) 2002-06-27
MXPA02001513A (es) 2002-07-02
OA11998A (en) 2006-04-18
US20040009560A1 (en) 2004-01-15
HU230600B1 (hu) 2017-02-28
CN1186446C (zh) 2005-01-26
ATE341632T1 (de) 2006-10-15
AR022646A1 (es) 2002-09-04
NO20020664L (no) 2002-02-11
CY1105778T1 (el) 2011-02-02
JP2003507017A (ja) 2003-02-25
KR100489856B1 (ko) 2005-05-17
BRPI0013119B8 (pt) 2021-05-25
UY26286A1 (es) 2001-03-16
BG106479A (bg) 2002-10-31
NO20020664D0 (no) 2002-02-11
CN1373809A (zh) 2002-10-09
CZ304402B6 (cs) 2014-04-16
AU778837B2 (en) 2004-12-23
BR0013119A (pt) 2002-04-23
MA26813A1 (fr) 2004-12-20
BG65902B1 (bg) 2010-04-30
CA2380872C (en) 2007-11-27
DK1200606T3 (da) 2007-01-08
DE60031126T2 (de) 2007-02-08
HUP0202487A2 (en) 2002-10-28
GT200000136A (es) 2002-02-01
KR20020029379A (ko) 2002-04-18
SK1392002A3 (en) 2002-12-03
US6632673B1 (en) 2003-10-14
HUP0202487A3 (en) 2004-07-28
PA8499501A1 (es) 2001-12-14
CZ2002296A3 (cs) 2002-08-14
PT1200606E (pt) 2006-12-29
AP2002002418A0 (en) 2002-03-31
JP3884651B2 (ja) 2007-02-21
US7858340B2 (en) 2010-12-28
WO2001012821A1 (en) 2001-02-22
BR0013119B1 (pt) 2014-02-25
PL203818B1 (pl) 2009-11-30
IL147563A (en) 2009-06-15
AU5838600A (en) 2001-03-13
ZA200201072B (en) 2003-04-30
EP1200606A1 (en) 2002-05-02
ES2272299T3 (es) 2007-05-01
TNSN00171A1 (fr) 2005-11-10
NZ516517A (en) 2003-10-31
EP1200606B1 (en) 2006-10-04
PE20010690A1 (es) 2001-07-06
IL147563A0 (en) 2002-08-14
DE60031126D1 (de) 2006-11-16
HRP20020130A2 (en) 2003-06-30
SK288086B6 (sk) 2013-06-03
PL353874A1 (en) 2003-12-01
CA2380872A1 (en) 2001-02-22
HK1046710A1 (en) 2003-01-24

Similar Documents

Publication Publication Date Title
AU2002224436A1 (en) Partition system with elevated raceway
AU2001272014A1 (en) Distributed simulation
AU2002225595A1 (en) Cellulose-based fire retardant composition
AU2001278694A1 (en) Avermectin derivatives
AU2002224409A1 (en) Partition system with worktools
IS6249A (is) Streptomyces avermitilis gen sem stýra hlutfallinu á B2:B1 avermektínum
ZA995872B (en) Streptomyces avermitilis regulatory genes for increased avermectin production.
IS6250A (is) Streptomyces avermitilis gen sem stýra hlutfallinu á B2:B1 avermektínum
IS5567A (is) Streptomyces avermitilis gen sem stýrir hlutfallinu milli B2:B1 avermektína
TWI341330B (en) Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
AU2690500A (en) Avermectin aglycon synthase genes
DK1200605T3 (da) Streptomyces avermitilis gen, der dirigerer forholdet imellem B2:B1 avermectiner
AU2002222660A1 (en) Pre-listed share circulation system
AU2001281419A1 (en) Ceiling board
AU8751901A (en) Supreme ultimate bodybuilding ball
AUPQ236699A0 (en) Enhanced keno based game
AUPQ547100A0 (en) Liver selective therapy
AU2000261885A1 (en) The multi-space structure amplifier
AUPQ282599A0 (en) Jackpot game
HK1055166A (en) Distributed simulation
AUPR028300A0 (en) Jackpot game
AU2002249774A1 (en) Interconnect
HK1054840A (en) Interconnect
AUPQ972000A0 (en) The milzo fire igniter