IS6435A - Aðferð til framleiðslu á sítalóprami - Google Patents

Aðferð til framleiðslu á sítalóprami

Info

Publication number
IS6435A
IS6435A IS6435A IS6435A IS6435A IS 6435 A IS6435 A IS 6435A IS 6435 A IS6435 A IS 6435A IS 6435 A IS6435 A IS 6435A IS 6435 A IS6435 A IS 6435A
Authority
IS
Iceland
Prior art keywords
citalopram
formula
diene
preparation
relates
Prior art date
Application number
IS6435A
Other languages
English (en)
Inventor
Petersen Hans
Felding Jakob
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of IS6435A publication Critical patent/IS6435A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/28—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Furan Compounds (AREA)
IS6435A 1999-12-28 2002-06-19 Aðferð til framleiðslu á sítalóprami IS6435A (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/DK1999/000739 WO2001047909A1 (en) 1999-12-28 1999-12-28 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
IS6435A true IS6435A (is) 2002-06-19

Family

ID=8157173

Family Applications (1)

Application Number Title Priority Date Filing Date
IS6435A IS6435A (is) 1999-12-28 2002-06-19 Aðferð til framleiðslu á sítalóprami

Country Status (26)

Country Link
US (1) US6762307B2 (is)
EP (1) EP1246812B1 (is)
JP (1) JP2003519136A (is)
KR (1) KR20020073489A (is)
CN (1) CN1398263A (is)
AT (1) ATE261953T1 (is)
AU (1) AU778751B2 (is)
BG (1) BG106939A (is)
CA (1) CA2395404A1 (is)
CZ (1) CZ20022213A3 (is)
DE (1) DE69915713T2 (is)
DK (1) DK1246812T3 (is)
EA (1) EA004742B1 (is)
ES (1) ES2219095T3 (is)
HU (1) HUP0203635A3 (is)
IL (1) IL150335A0 (is)
IS (1) IS6435A (is)
MX (1) MXPA02006503A (is)
NO (1) NO20023126L (is)
NZ (1) NZ519739A (is)
PL (1) PL355532A1 (is)
PT (1) PT1246812E (is)
SI (1) SI1246812T1 (is)
SK (1) SK9282002A3 (is)
TR (1) TR200201678T2 (is)
WO (1) WO2001047909A1 (is)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1173431T4 (da) 1999-04-14 2010-01-04 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
DK1246813T3 (da) 1999-12-30 2004-03-01 Lundbeck & Co As H Fremgangsmåde til fremstilling af Citalopram
AU3033700A (en) 2000-01-14 2001-07-24 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
KR20020080485A (ko) 2000-03-13 2002-10-23 하. 룬트벡 아크티에 셀스카브 5-치환 1-(4-플루오로페닐)-1,3-디히드로이소벤조푸란의단계적 알킬화
AU2001242298A1 (en) 2000-03-13 2001-09-24 H Lunbeck A/S Method for the preparation of citalopram
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
ES2214400T3 (es) 2000-03-14 2004-09-16 H. Lundbeck A/S Metodo para la preparacion de citalopram.
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
AU2003223105A1 (en) * 2003-03-24 2004-10-18 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
ITMI20040717A1 (it) * 2004-04-09 2004-07-09 Adorkem Technology Spa Procedimento chemo-enzimatico per la preparazione dell'escitalopram
JP2006008603A (ja) * 2004-06-25 2006-01-12 Sumitomo Chemical Co Ltd 光学活性シタロプラムの製造方法、その中間体およびその製造方法
JP2009515840A (ja) * 2005-11-14 2009-04-16 ハー・ルンドベック・アクチエゼルスカベット エスシタロプラムの製造方法
US20110230666A1 (en) * 2008-06-03 2011-09-22 Shodhana Laboratories Limited process for the separation of enantiomerically pure compounds
WO2010004575A2 (en) * 2008-06-16 2010-01-14 Shodhana Laboratories Limited Preparation of escitalopram, its salts and intermediates

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (is) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
SK283309B6 (sk) 1997-07-08 2003-05-02 H. Lundbeck A/S Spôsob výroby citalopramu a medziprodukty
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
DK1042310T3 (da) 1997-11-11 2002-12-02 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
ES2189502T3 (es) 1998-10-20 2003-07-01 Lundbeck & Co As H Metodo para la prevencion de citalopram.
IL143422A0 (en) 1998-12-23 2002-04-21 Lundbeck & Co As H Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
DK1173431T4 (da) 1999-04-14 2010-01-04 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
CH692421A5 (de) 1999-10-25 2002-06-14 Lundbeck & Co As H Verfahren zur Herstellung von Citalopram.
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
DK1246813T3 (da) 1999-12-30 2004-03-01 Lundbeck & Co As H Fremgangsmåde til fremstilling af Citalopram
AU3033700A (en) 2000-01-14 2001-07-24 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
FR2805812A1 (fr) 2000-02-24 2001-09-07 Lundbeck & Co As H Procede de preparation du citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
CA2354877C (en) 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
CA2360303C (en) 2000-12-22 2003-08-12 Marco Villa Process for the preparation of pure citalopram
SK284418B6 (sk) 2000-12-28 2005-04-01 H. Lundbeck A/S Spôsob výroby citalopramu

Also Published As

Publication number Publication date
MXPA02006503A (es) 2002-12-09
EA200200719A1 (ru) 2002-12-26
CN1398263A (zh) 2003-02-19
SK9282002A3 (en) 2002-11-06
SI1246812T1 (en) 2004-08-31
HUP0203635A3 (en) 2005-02-28
US6762307B2 (en) 2004-07-13
AU1858300A (en) 2001-07-09
NO20023126D0 (no) 2002-06-27
AU778751B2 (en) 2004-12-16
EP1246812B1 (en) 2004-03-17
EA004742B1 (ru) 2004-08-26
DK1246812T3 (da) 2004-07-05
KR20020073489A (ko) 2002-09-26
NO20023126L (no) 2002-06-27
WO2001047909A1 (en) 2001-07-05
DE69915713T2 (de) 2005-03-03
TR200201678T2 (tr) 2002-10-21
CZ20022213A3 (cs) 2002-09-11
US20030060641A1 (en) 2003-03-27
IL150335A0 (en) 2002-12-01
CA2395404A1 (en) 2001-07-05
ES2219095T3 (es) 2004-11-16
HUP0203635A2 (hu) 2003-02-28
BG106939A (en) 2003-03-31
JP2003519136A (ja) 2003-06-17
DE69915713D1 (de) 2004-04-22
PL355532A1 (en) 2004-05-04
EP1246812A1 (en) 2002-10-09
ATE261953T1 (de) 2004-04-15
PT1246812E (pt) 2004-08-31
NZ519739A (en) 2004-03-26

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