IS7279A - Kristalskennt form ríbófúransýlurónamíð afleiðu; mennsk adenósín A2A viðtakagerandefni - Google Patents

Kristalskennt form ríbófúransýlurónamíð afleiðu; mennsk adenósín A2A viðtakagerandefni

Info

Publication number
IS7279A
IS7279A IS7279A IS7279A IS7279A IS 7279 A IS7279 A IS 7279A IS 7279 A IS7279 A IS 7279A IS 7279 A IS7279 A IS 7279A IS 7279 A IS7279 A IS 7279A
Authority
IS
Iceland
Prior art keywords
acyluronamide
ribofuran
derivative
crystalline form
receptor agonist
Prior art date
Application number
IS7279A
Other languages
English (en)
Inventor
Vernon Silk Terence
Duncan Smith Julian
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of IS7279A publication Critical patent/IS7279A/is

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nanotechnology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
IS7279A 2001-12-06 2004-05-21 Kristalskennt form ríbófúransýlurónamíð afleiðu; mennsk adenósín A2A viðtakagerandefni IS7279A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0129273.9A GB0129273D0 (en) 2001-12-06 2001-12-06 Crystalline drug form
PCT/IB2002/004979 WO2003048180A1 (en) 2001-12-06 2002-11-27 Crystalline form of a ribofuranosyluronamide derivative; a human adenosine a2a receptor agonist

Publications (1)

Publication Number Publication Date
IS7279A true IS7279A (is) 2004-05-21

Family

ID=9927165

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7279A IS7279A (is) 2001-12-06 2004-05-21 Kristalskennt form ríbófúransýlurónamíð afleiðu; mennsk adenósín A2A viðtakagerandefni

Country Status (40)

Country Link
US (3) US20030144243A1 (is)
EP (1) EP1456219B1 (is)
JP (1) JP4184279B2 (is)
KR (1) KR100554333B1 (is)
CN (1) CN100381454C (is)
AP (1) AP2004003056A0 (is)
AR (2) AR038547A1 (is)
AT (1) ATE364615T1 (is)
AU (2) AU2002351056A1 (is)
BR (1) BR0214747A (is)
CA (1) CA2468847C (is)
CY (1) CY1106822T1 (is)
DE (1) DE60220713T2 (is)
DK (1) DK1456219T3 (is)
EA (1) EA006857B1 (is)
EC (1) ECSP045141A (is)
ES (1) ES2286303T3 (is)
GB (1) GB0129273D0 (is)
GT (2) GT200200257A (is)
HN (1) HN2002000352A (is)
HR (1) HRP20040516A2 (is)
HU (1) HUP0700046A2 (is)
IL (2) IL162101A0 (is)
IS (1) IS7279A (is)
MA (1) MA27151A1 (is)
MX (1) MXPA04005505A (is)
NO (1) NO20042837L (is)
NZ (1) NZ533053A (is)
OA (1) OA12737A (is)
PA (2) PA8560501A1 (is)
PE (2) PE20030722A1 (is)
PL (1) PL370971A1 (is)
PT (1) PT1456219E (is)
RS (1) RS49504A (is)
SV (1) SV2004001425A (is)
TN (1) TNSN04103A1 (is)
TW (2) TW200301129A (is)
UY (1) UY27568A1 (is)
WO (2) WO2003047597A1 (is)
ZA (1) ZA200403967B (is)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030225089A1 (en) * 2002-04-10 2003-12-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and p38 kinase inhibitors
DE10345065A1 (de) * 2003-09-26 2005-04-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
PE20060272A1 (es) 2004-05-24 2006-05-22 Glaxo Group Ltd (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
WO2021084791A1 (ja) * 2019-10-28 2021-05-06 有限会社イムノ アデノシンａ２ａ受容体を標的とする組成物
CN115400140B (zh) * 2022-01-27 2024-02-20 宁波熙健医药科技有限公司 呋喃核糖基吡啶衍生物用于预防或治疗癫痫或惊厥的用途

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KR0166088B1 (ko) 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista
GB9711643D0 (en) 1997-06-05 1997-07-30 Janssen Pharmaceutica Nv Glass thermoplastic systems
GB9913932D0 (en) * 1999-06-15 1999-08-18 Pfizer Ltd Purine derivatives
WO2001020089A1 (fr) 1999-09-10 2001-03-22 Maeda Corporation Structure de beton et procede de construction
GB0003960D0 (en) * 2000-02-18 2000-04-12 Pfizer Ltd Purine derivatives
GB0009583D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory formulations
GB0009592D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Respiratory combinations
GB0009606D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Therapeutic combinations
GB0009605D0 (en) * 2000-04-18 2000-06-07 Glaxo Group Ltd Medicaments
TWI227240B (en) * 2000-06-06 2005-02-01 Pfizer 2-aminocarbonyl-9H-purine derivatives
AU5800800A (en) 2000-07-26 2002-02-05 Swisscom Mobile Ag Method for the assembly of a mobile radio network base station and connection ofthe base station to the network
PL366899A1 (en) * 2001-05-25 2005-02-07 Pfizer Inc. An adenosine a2a receptor agonist and an anticholinergic agent in combination for treating obstructive airways diseases

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US6852746B2 (en) 2005-02-08
GT200200256A (es) 2003-07-03
EP1456219A1 (en) 2004-09-15
AR037633A1 (es) 2004-11-17
AU2002351056A1 (en) 2003-06-17
EA200400638A1 (ru) 2004-10-28
WO2003047597A1 (en) 2003-06-12
HUP0700046A2 (en) 2007-03-28
MXPA04005505A (es) 2005-06-03
HN2002000352A (es) 2003-07-23
JP4184279B2 (ja) 2008-11-19
CA2468847A1 (en) 2003-06-12
TNSN04103A1 (fr) 2006-06-01
KR100554333B1 (ko) 2006-02-22
ATE364615T1 (de) 2007-07-15
PE20030722A1 (es) 2003-08-29
KR20050058272A (ko) 2005-06-16
WO2003048180A1 (en) 2003-06-12
OA12737A (en) 2006-06-29
US20030144243A1 (en) 2003-07-31
HRP20040516A2 (en) 2004-10-31
IL162101A (en) 2010-04-29
IL162101A0 (en) 2005-11-20
HK1071143A1 (zh) 2005-07-08
PL370971A1 (en) 2005-06-13
EP1456219B1 (en) 2007-06-13
NO20042837L (no) 2004-08-24
PA8560301A1 (es) 2003-11-12
SV2004001425A (es) 2004-05-07
PA8560501A1 (es) 2003-09-17
JP2005513043A (ja) 2005-05-12
AU2002347509A1 (en) 2003-06-17
BR0214747A (pt) 2004-09-14
AR038547A1 (es) 2005-01-19
US20030158145A1 (en) 2003-08-21
GT200200257A (es) 2003-07-11
ZA200403967B (en) 2006-05-31
CY1106822T1 (el) 2012-05-23
UY27568A1 (es) 2003-07-31
DE60220713D1 (de) 2007-07-26
EA006857B1 (ru) 2006-04-28
TW200301130A (en) 2003-07-01
ES2286303T3 (es) 2007-12-01
TW200301129A (en) 2003-07-01
CN100381454C (zh) 2008-04-16
CA2468847C (en) 2008-10-21
DE60220713T2 (de) 2008-03-06
GB0129273D0 (en) 2002-01-23
CN1599745A (zh) 2005-03-23
AU2002347509B2 (en) 2008-09-18
US20050085437A1 (en) 2005-04-21
PE20030822A1 (es) 2003-10-04
US7022727B2 (en) 2006-04-04
ECSP045141A (es) 2004-07-23
AP2004003056A0 (en) 2004-06-30
RS49504A (sr) 2006-10-27
MA27151A1 (fr) 2005-01-03
DK1456219T3 (da) 2007-09-24
NZ533053A (en) 2006-09-29
PT1456219E (pt) 2007-08-03

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