IS7433A - Heteróhringlaga amíðafleiður með tálmavirkni gegnglýkógenfosfórýlasa - Google Patents
Heteróhringlaga amíðafleiður með tálmavirkni gegnglýkógenfosfórýlasaInfo
- Publication number
- IS7433A IS7433A IS7433A IS7433A IS7433A IS 7433 A IS7433 A IS 7433A IS 7433 A IS7433 A IS 7433A IS 7433 A IS7433 A IS 7433A IS 7433 A IS7433 A IS 7433A
- Authority
- IS
- Iceland
- Prior art keywords
- amide derivatives
- glycogen phosphorylase
- heterocyclic amide
- phosphorylase inhibition
- inhibition
- Prior art date
Links
- 229920002527 Glycogen Polymers 0.000 title 1
- -1 Heterocyclic amide Chemical class 0.000 title 1
- 102000009097 Phosphorylases Human genes 0.000 title 1
- 108010073135 Phosphorylases Proteins 0.000 title 1
- 229940096919 glycogen Drugs 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0205170.4A GB0205170D0 (en) | 2002-03-06 | 2002-03-06 | Chemical compounds |
| PCT/GB2003/000875 WO2003074531A1 (en) | 2002-03-06 | 2003-03-04 | Heterocyclic amide derivatives having glycogen phosphorylase inhibitory activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS7433A true IS7433A (is) | 2004-09-01 |
Family
ID=9932334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7433A IS7433A (is) | 2002-03-06 | 2004-09-01 | Heteróhringlaga amíðafleiður með tálmavirkni gegnglýkógenfosfórýlasa |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7122567B2 (is) |
| EP (1) | EP1483271B1 (is) |
| JP (1) | JP2005524669A (is) |
| KR (1) | KR20040091101A (is) |
| CN (1) | CN1307183C (is) |
| AR (1) | AR038886A1 (is) |
| AT (1) | ATE346072T1 (is) |
| AU (1) | AU2003209445A1 (is) |
| BR (1) | BR0308145A (is) |
| CA (1) | CA2477125A1 (is) |
| DE (1) | DE60309849T2 (is) |
| DK (1) | DK1483271T3 (is) |
| ES (1) | ES2276092T3 (is) |
| GB (1) | GB0205170D0 (is) |
| IL (1) | IL163802A0 (is) |
| IS (1) | IS7433A (is) |
| MX (1) | MXPA04008611A (is) |
| NO (1) | NO20044033L (is) |
| NZ (1) | NZ534684A (is) |
| PL (1) | PL372772A1 (is) |
| PT (1) | PT1483271E (is) |
| RU (1) | RU2004125145A (is) |
| TW (1) | TW200306176A (is) |
| WO (1) | WO2003074531A1 (is) |
| ZA (1) | ZA200406685B (is) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0222909D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| GB0222912D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| JP4630267B2 (ja) * | 2002-12-25 | 2011-02-09 | 第一三共株式会社 | ジアミン誘導体 |
| MXPA05006989A (es) | 2002-12-25 | 2005-09-22 | Daiichi Seiyaku Co | Derivados de diamina. |
| GB0318463D0 (en) * | 2003-08-07 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| GB0319759D0 (en) * | 2003-08-22 | 2003-09-24 | Astrazeneca Ab | Chemical compounds |
| RU2361862C2 (ru) | 2003-12-29 | 2009-07-20 | Сепракор Инк. | Пиррольные и пиразольные ингибиторы daao |
| WO2006055435A1 (en) | 2004-11-15 | 2006-05-26 | Bristol-Myers Squibb Company | 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors |
| US7365061B2 (en) | 2004-11-15 | 2008-04-29 | Bristol-Myers Squibb Company | 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
| WO2006055462A1 (en) * | 2004-11-15 | 2006-05-26 | Bristol-Myers Squibb Company | 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
| WO2006053274A2 (en) * | 2004-11-15 | 2006-05-18 | Bristol-Myers Squibb Company | 2-amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
| TWI281231B (en) * | 2004-12-20 | 2007-05-11 | Hynix Semiconductor Inc | Method for forming storage node of capacitor in semiconductor device |
| US8053603B2 (en) | 2006-01-06 | 2011-11-08 | Sunovion Pharmaceuticals Inc. | Tetralone-based monoamine reuptake inhibitors |
| BRPI0706365A2 (pt) | 2006-01-06 | 2011-03-22 | Sepracor Inc | Cicloalquilaminas como inibidores da recaptação de monoamina |
| EP2816024B8 (en) | 2006-03-31 | 2018-04-04 | Sunovion Pharmaceuticals Inc. | Chiral amines |
| PE20110235A1 (es) | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | Combinaciones farmaceuticas que comprenden linagliptina y metmorfina |
| US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US7902252B2 (en) | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| CA2688493C (en) | 2007-05-31 | 2016-04-19 | Sepracor Inc. | Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors |
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| DE200740C (is) | ||||
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| US4668769A (en) | 1985-08-02 | 1987-05-26 | Hoover Dennis J | Oxa- and azahomocyclostatine polypeptides |
| US4720503A (en) | 1985-08-02 | 1988-01-19 | Merck & Co., Inc. | N-substituted fused-heterocyclic carboxamide derivatives as dual cyclooxygenase and lipoxygenase inhibitors |
| US4599198A (en) | 1985-08-02 | 1986-07-08 | Pfizer Inc. | Intermediates in polypeptide synthesis |
| FR2601368B1 (fr) | 1986-07-08 | 1989-04-07 | Synthelabo | Derives de nitrofuranne, leur preparation et leur application en therapeutique. |
| DE3629545A1 (de) | 1986-08-30 | 1988-03-10 | Bayer Ag | Dihydropyridinverbindungen, verfahren zu ihrer herstellung und ihre verwendung |
| US4751231A (en) | 1987-09-16 | 1988-06-14 | Merck & Co., Inc. | Substituted thieno[2,3-b]pyrrole-5-sulfonamides as antiglaucoma agents |
| JPH04179949A (ja) | 1990-11-15 | 1992-06-26 | Fuji Photo Film Co Ltd | 新規な色素形成カプラーおよび該カプラーを用いたハロゲン化銀カラー写真感光材料 |
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| US5863903A (en) | 1994-03-09 | 1999-01-26 | Novo Nordisk A/S | Use of hydroxy alkyl piperidine and pyrrolidine compounds to treat diabetes |
| EP0749423B1 (en) | 1994-03-09 | 2003-06-18 | Novo Nordisk A/S | Piperidines and pyrrolidines |
| FR2723739B1 (fr) | 1994-08-19 | 1997-02-14 | Sanofi Sa | Derives de glycinamide, procedes pour leur preparation et medicaments les contenant. |
| DE4445968A1 (de) | 1994-12-22 | 1996-06-27 | Bayer Ag | Verwendung von Sulfonylguanazinen |
| CA2342471C (en) | 1995-06-06 | 2002-10-29 | Judith L. Treadway | Heterocyclecarbonylmethyl amine intermediates |
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| IL124109A (en) | 1995-09-08 | 2001-10-31 | Novo Nordisk As | Pharmaceutical composition of 2-alkylpyrrolidines for use in the manufacture of medicaments for the treatment of diabetes |
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| US5952322A (en) | 1996-12-05 | 1999-09-14 | Pfizer Inc. | Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors |
| JP2001505585A (ja) | 1996-12-16 | 2001-04-24 | 藤沢薬品工業株式会社 | 新規アミド化合物およびそれらの一酸化窒素シンターゼ阻害剤としての用途 |
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| HUP0003362A3 (en) | 1997-05-06 | 2001-04-28 | Novo Nordisk As | Piperidine derivatives and pharmaceutical compositions containing them |
| UA57811C2 (uk) | 1997-11-21 | 2003-07-15 | Пфайзер Продактс Інк. | Фармацевтична композиція, що містить інгібітор альдозоредуктази та інгібітор глікогенфосфорилази (варіанти), комплект, який її включає, та способи лікування ссавців зі станом інсулінорезистентності |
| MY153569A (en) | 1998-01-20 | 2015-02-27 | Mitsubishi Tanabe Pharma Corp | Inhibitors of ?4 mediated cell adhesion |
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| EP0978279A1 (en) | 1998-08-07 | 2000-02-09 | Pfizer Products Inc. | Inhibitors of human glycogen phosphorylase |
| DE60045474D1 (de) | 1999-01-13 | 2011-02-17 | Univ New York State Res Found | Neues verfahren zum erschaffen von proteinkinase-inhibitoren |
| JP2002536410A (ja) | 1999-02-12 | 2002-10-29 | ノボ ノルディスク アクティーゼルスカブ | 肥満の治療又は予防もしくは食欲の調節を目的とした薬学的組成物の製造におけるピロリジン誘導体の使用 |
| JP3795305B2 (ja) | 1999-07-19 | 2006-07-12 | 田辺製薬株式会社 | 医薬組成物 |
| US6043091A (en) | 1999-07-19 | 2000-03-28 | Isis Pharmaceuticals Inc. | Antisense modulation of liver glycogen phosphorylase expression |
| JP2003510304A (ja) | 1999-09-29 | 2003-03-18 | ノボ ノルディスク アクティーゼルスカブ | 新規芳香族化合物 |
| PT1088824E (pt) | 1999-09-30 | 2004-04-30 | Pfizer Prod Inc | Pirrolil-amidas biciclicas como inibidores de glicogenio-fosforilase |
| SE9903998D0 (sv) | 1999-11-03 | 1999-11-03 | Astra Ab | New compounds |
| ATE318809T1 (de) | 1999-11-05 | 2006-03-15 | Sod Conseils Rech Applic | Heterocyclische verbindungen und ihre verwendung als medikamente |
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| AR028253A1 (es) | 2000-03-16 | 2003-04-30 | Pfizer Prod Inc | Inhibidores de la glucogeno fosforilasa |
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| US20020028826A1 (en) | 2000-06-15 | 2002-03-07 | Robl Jeffrey A. | HMG-CoA reductase inhibitors and method |
| US20020013334A1 (en) | 2000-06-15 | 2002-01-31 | Robl Jeffrey A. | HMG-CoA reductase inhibitors and method |
| IL144507A0 (en) | 2000-07-31 | 2002-05-23 | Pfizer Prod Inc | Use of glycogen phosphorylase inhibitors to inhibit tumor growth |
| GB0021831D0 (en) * | 2000-09-06 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
| AU2001288110A1 (en) | 2000-09-27 | 2002-04-08 | Takeda Chemical Industries Ltd. | Spiro compounds |
| HU227197B1 (en) | 2000-10-24 | 2010-10-28 | Richter Gedeon Nyrt | Nmda receptor antagonist carboxylic acid amide derivatives and pharmaceutical compositions containing them |
| EP1338594A4 (en) | 2000-11-01 | 2004-06-16 | Shionogi & Co | PGD2 RECEPTOR ANTAGONIST PHARMACEUTICAL COMPOSITIONS |
| AU2002256053A1 (en) | 2001-04-04 | 2002-10-21 | Genzyme Corporation | Novel bgp compounds for therapy and diagnosis and methods for using same |
| PE20021091A1 (es) | 2001-05-25 | 2003-02-04 | Aventis Pharma Gmbh | Derivados de fenilurea sustituidos con carbonamida y procedimiento para su preparacion |
| AU2002308706A1 (en) | 2001-06-01 | 2002-12-16 | Eli Lilly And Company | Glp-1 formulations with protracted time action |
| US20050054696A1 (en) | 2001-10-29 | 2005-03-10 | Takeshi Nakamura | Indole compounds and medicinal use thereof |
| CA2468159A1 (en) | 2001-11-27 | 2003-06-05 | Merck & Co., Inc. | 4-aminoquinoline compounds |
| MXPA03000966A (es) | 2002-02-28 | 2003-09-04 | Pfizer Prod Inc | Agentes antidiabeticos. |
| GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| AU2003227360A1 (en) | 2002-04-25 | 2003-11-10 | Yamanouchi Pharmaceutical Co., Ltd. | Novel amide derivatives or salts thereof |
| US7057046B2 (en) | 2002-05-20 | 2006-06-06 | Bristol-Myers Squibb Company | Lactam glycogen phosphorylase inhibitors and method of use |
| GB0222912D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| GB0222909D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| MXPA05004968A (es) | 2002-11-07 | 2005-08-02 | Pfizer Prod Inc | N-(indol-z-carbonil)amidas como agentes anti-diabeticos. |
| US7098235B2 (en) | 2002-11-14 | 2006-08-29 | Bristol-Myers Squibb Co. | Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds |
| JP2004196702A (ja) | 2002-12-18 | 2004-07-15 | Yamanouchi Pharmaceut Co Ltd | 新規なアミド誘導体又はその塩 |
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| EP1633709A1 (en) | 2003-04-30 | 2006-03-15 | Pfizer Products Inc. | Anti-diabetic agents |
| WO2004113345A1 (ja) | 2003-06-20 | 2004-12-29 | Japan Tobacco Inc. | 縮合ピロール化合物及びその医薬用途 |
| GB0318463D0 (en) | 2003-08-07 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| GB0318464D0 (en) | 2003-08-07 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| GB0319690D0 (en) | 2003-08-22 | 2003-09-24 | Astrazeneca Ab | Chemical compounds |
| GB0319759D0 (en) | 2003-08-22 | 2003-09-24 | Astrazeneca Ab | Chemical compounds |
| WO2005020985A1 (en) | 2003-08-29 | 2005-03-10 | Astrazeneca Ab | Indolamide derivatives which possess glycogen phosphorylase inhibitory activity |
| WO2005020986A1 (en) | 2003-08-29 | 2005-03-10 | Astrazeneca Ab | Heterocyclic amide derivatives which posses glycogen phosphorylase inhibitory activity |
| GB0320422D0 (en) | 2003-08-30 | 2003-10-01 | Astrazeneca Ab | Chemical compounds |
-
2002
- 2002-03-06 GB GBGB0205170.4A patent/GB0205170D0/en not_active Ceased
-
2003
- 2003-03-04 WO PCT/GB2003/000875 patent/WO2003074531A1/en not_active Ceased
- 2003-03-04 CA CA002477125A patent/CA2477125A1/en not_active Abandoned
- 2003-03-04 DE DE60309849T patent/DE60309849T2/de not_active Expired - Fee Related
- 2003-03-04 AU AU2003209445A patent/AU2003209445A1/en not_active Abandoned
- 2003-03-04 RU RU2004125145/04A patent/RU2004125145A/ru not_active Application Discontinuation
- 2003-03-04 AT AT03743418T patent/ATE346072T1/de not_active IP Right Cessation
- 2003-03-04 BR BR0308145-1A patent/BR0308145A/pt not_active IP Right Cessation
- 2003-03-04 PL PL03372772A patent/PL372772A1/xx not_active Application Discontinuation
- 2003-03-04 EP EP03743418A patent/EP1483271B1/en not_active Expired - Lifetime
- 2003-03-04 KR KR10-2004-7013865A patent/KR20040091101A/ko not_active Ceased
- 2003-03-04 MX MXPA04008611A patent/MXPA04008611A/es active IP Right Grant
- 2003-03-04 PT PT03743418T patent/PT1483271E/pt unknown
- 2003-03-04 ES ES03743418T patent/ES2276092T3/es not_active Expired - Lifetime
- 2003-03-04 NZ NZ534684A patent/NZ534684A/en unknown
- 2003-03-04 IL IL16380203A patent/IL163802A0/xx unknown
- 2003-03-04 US US10/506,746 patent/US7122567B2/en not_active Expired - Fee Related
- 2003-03-04 DK DK03743418T patent/DK1483271T3/da active
- 2003-03-04 JP JP2003572999A patent/JP2005524669A/ja not_active Withdrawn
- 2003-03-04 CN CNB038051249A patent/CN1307183C/zh not_active Expired - Fee Related
- 2003-03-05 TW TW092104655A patent/TW200306176A/zh unknown
- 2003-03-06 AR ARP030100766A patent/AR038886A1/es unknown
-
2004
- 2004-08-23 ZA ZA200406685A patent/ZA200406685B/en unknown
- 2004-09-01 IS IS7433A patent/IS7433A/is unknown
- 2004-09-24 NO NO20044033A patent/NO20044033L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AR038886A1 (es) | 2005-02-02 |
| RU2004125145A (ru) | 2005-06-10 |
| GB0205170D0 (en) | 2002-04-17 |
| PT1483271E (pt) | 2007-02-28 |
| TW200306176A (en) | 2003-11-16 |
| HK1070365A1 (en) | 2005-06-17 |
| BR0308145A (pt) | 2004-12-07 |
| MXPA04008611A (es) | 2004-12-06 |
| DE60309849D1 (de) | 2007-01-04 |
| CN1639167A (zh) | 2005-07-13 |
| CN1307183C (zh) | 2007-03-28 |
| CA2477125A1 (en) | 2003-09-12 |
| NO20044033L (no) | 2004-11-25 |
| NZ534684A (en) | 2006-02-24 |
| EP1483271B1 (en) | 2006-11-22 |
| JP2005524669A (ja) | 2005-08-18 |
| KR20040091101A (ko) | 2004-10-27 |
| PL372772A1 (en) | 2005-08-08 |
| IL163802A0 (en) | 2005-12-18 |
| US20050131052A1 (en) | 2005-06-16 |
| EP1483271A1 (en) | 2004-12-08 |
| DE60309849T2 (de) | 2007-06-14 |
| DK1483271T3 (da) | 2007-02-19 |
| ZA200406685B (en) | 2005-10-31 |
| ATE346072T1 (de) | 2006-12-15 |
| ES2276092T3 (es) | 2007-06-16 |
| AU2003209445A1 (en) | 2003-09-16 |
| WO2003074531A1 (en) | 2003-09-12 |
| US7122567B2 (en) | 2006-10-17 |
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