IS7845A - Forröðuð þríhringja integrase hindrandi efnasambönd - Google Patents

Forröðuð þríhringja integrase hindrandi efnasambönd

Info

Publication number
IS7845A
IS7845A IS7845A IS7845A IS7845A IS 7845 A IS7845 A IS 7845A IS 7845 A IS7845 A IS 7845A IS 7845 A IS7845 A IS 7845A IS 7845 A IS7845 A IS 7845A
Authority
IS
Iceland
Prior art keywords
betrayed
tri
ring
inhibitory compounds
integrase inhibitory
Prior art date
Application number
IS7845A
Other languages
English (en)
Inventor
M. Chen James
Chen Xiaowu
Fardis Maria
Jin Haolun
U. Kim Choung
N. Schacherer Laura
Original Assignee
Gilead Science, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Science, Inc. filed Critical Gilead Science, Inc.
Publication of IS7845A publication Critical patent/IS7845A/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/20—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IS7845A 2002-10-16 2005-05-13 Forröðuð þríhringja integrase hindrandi efnasambönd IS7845A (is)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41896302P 2002-10-16 2002-10-16
US47878303P 2003-06-16 2003-06-16
PCT/US2003/032666 WO2004035576A2 (en) 2002-10-16 2003-10-16 Pre-organized tricyclic integrase inhibitor compounds

Publications (1)

Publication Number Publication Date
IS7845A true IS7845A (is) 2005-05-13

Family

ID=32110203

Family Applications (1)

Application Number Title Priority Date Filing Date
IS7845A IS7845A (is) 2002-10-16 2005-05-13 Forröðuð þríhringja integrase hindrandi efnasambönd

Country Status (19)

Country Link
US (3) US20040157804A1 (is)
EP (1) EP1558613A2 (is)
JP (1) JP2006514099A (is)
KR (1) KR20050087787A (is)
CN (1) CN100374438C (is)
AP (1) AP1858A (is)
AU (2) AU2003301439A1 (is)
BR (1) BR0315405A (is)
CA (1) CA2501881A1 (is)
EA (1) EA011399B1 (is)
HR (1) HRP20050431A2 (is)
IS (1) IS7845A (is)
MX (1) MXPA05003950A (is)
NO (1) NO20052378L (is)
NZ (1) NZ539264A (is)
OA (1) OA13079A (is)
PL (1) PL377966A1 (is)
UA (1) UA79830C2 (is)
WO (2) WO2004035577A2 (is)

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US7713973B2 (en) 2004-10-15 2010-05-11 Takeda Pharmaceutical Company Limited Kinase inhibitors
AR057023A1 (es) * 2005-05-16 2007-11-14 Gilead Sciences Inc Compuestos heterociclicos con propiedades inhibidoras de hiv-integrasa
ATE533766T1 (de) 2005-05-19 2011-12-15 Merck Canada Inc Chinolinderivate als ep4-antagonisten
JP2009502964A (ja) * 2005-07-27 2009-01-29 ギリアード サイエンシーズ， インコーポレイテッド Ｈｉｖを阻害するための抗ウイルス性ホスホン酸結合体
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PT2660239T (pt) 2008-07-25 2017-02-24 Shionogi & Co Compostos químicos como intermediários sintéticos
MX2011000971A (es) * 2008-07-28 2011-06-24 Polymedix Inc Compuestos antipaludicos.
MX351942B (es) 2008-12-11 2017-11-03 Shionogi & Co Sintesis de inhibidores de integrasa de vih de carbamoil-piridona e intermediarios.
EP2376453B1 (en) 2008-12-11 2019-11-20 VIIV Healthcare Company Intermediates for carbamoylpyridone hiv integrase inhibitors
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CN109305989B (zh) * 2017-07-28 2021-02-26 四川海思科制药有限公司 一种磷酰胺衍生物及制备方法和用途
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Also Published As

Publication number Publication date
JP2006514099A (ja) 2006-04-27
HRP20050431A2 (en) 2005-10-31
US20040167124A1 (en) 2004-08-26
US20090029939A1 (en) 2009-01-29
WO2004035576A3 (en) 2004-06-24
NZ539264A (en) 2007-08-31
AP1858A (en) 2008-06-30
EA200500660A1 (ru) 2005-10-27
KR20050087787A (ko) 2005-08-31
MXPA05003950A (es) 2005-06-17
US7253180B2 (en) 2007-08-07
EA011399B1 (ru) 2009-02-27
AU2003301306A1 (en) 2004-05-04
PL377966A1 (pl) 2006-02-20
NO20052378D0 (no) 2005-05-13
UA79830C2 (en) 2007-07-25
BR0315405A (pt) 2005-08-09
CN1726212A (zh) 2006-01-25
OA13079A (en) 2006-11-10
CA2501881A1 (en) 2004-04-29
US20040157804A1 (en) 2004-08-12
AU2003301439A1 (en) 2004-05-04
AP2005003279A0 (en) 2005-06-30
WO2004035576A2 (en) 2004-04-29
EP1558613A2 (en) 2005-08-03
AU2003301439A8 (en) 2004-05-04
CN100374438C (zh) 2008-03-12
NO20052378L (no) 2005-07-18
WO2004035577A3 (en) 2004-07-29
WO2004035577A2 (en) 2004-04-29

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