IS8077A - Risahringa qínazólínafleiður sem miðlar gegn fjölgun - Google Patents

Risahringa qínazólínafleiður sem miðlar gegn fjölgun

Info

Publication number
IS8077A
IS8077A IS8077A IS8077A IS8077A IS 8077 A IS8077 A IS 8077A IS 8077 A IS8077 A IS 8077A IS 8077 A IS8077 A IS 8077A IS 8077 A IS8077 A IS 8077A
Authority
IS
Iceland
Prior art keywords
giant
quinazoline derivatives
mediate proliferation
mediate
proliferation
Prior art date
Application number
IS8077A
Other languages
English (en)
Other versions
IS3030B (is
Inventor
Jean Edgard Freyne Eddy
Pietro Suren Perera Timothy
Jan Rita Rombouts Frederik
Jacobus Johannes Antonius Buijnsters Peter
Willems Marc
Stanislas Marcella Diels Gaston
Constant Johan Embrechts Werner
Ten Holte Peter
Schultz-Fademrecht Carsten
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33493782&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS8077(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of IS8077A publication Critical patent/IS8077A/is
Publication of IS3030B publication Critical patent/IS3030B/is

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/93—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IS8077A 2003-05-27 2005-10-14 Stórhringlaga kínasólín afleiður sem hemla á frumuskiptingu IS3030B (is)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP0305723 2003-05-27
EP0310266 2003-09-15
EP0351061 2003-12-18
PCT/EP2004/005621 WO2004105765A1 (en) 2003-05-27 2004-05-25 Macrocyclic quinazoline derivatives as antiproliferative agents

Publications (2)

Publication Number Publication Date
IS8077A true IS8077A (is) 2005-10-14
IS3030B IS3030B (is) 2021-06-15

Family

ID=33493782

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8077A IS3030B (is) 2003-05-27 2005-10-14 Stórhringlaga kínasólín afleiður sem hemla á frumuskiptingu

Country Status (31)

Country Link
US (4) US7648975B2 (is)
EP (2) EP2305687A1 (is)
JP (1) JP4887151B2 (is)
KR (1) KR101143878B1 (is)
CN (1) CN102718775B (is)
AR (2) AR045687A1 (is)
AT (1) ATE544454T1 (is)
AU (1) AU2004243487B2 (is)
BR (1) BRPI0410714B8 (is)
CA (1) CA2525214C (is)
CL (1) CL2004001267A1 (is)
CO (1) CO5640038A2 (is)
CY (1) CY1113002T1 (is)
DK (1) DK1633365T3 (is)
EA (1) EA009064B1 (is)
ES (1) ES2381976T3 (is)
HR (1) HRP20120351T1 (is)
IL (3) IL172154A0 (is)
IS (1) IS3030B (is)
JO (1) JO2785B1 (is)
MX (1) MXPA05012762A (is)
MY (1) MY148633A (is)
NO (1) NO334209B1 (is)
NZ (1) NZ544154A (is)
PA (1) PA8603801A1 (is)
PL (1) PL1633365T3 (is)
PT (1) PT1633365E (is)
SI (1) SI1633365T1 (is)
TW (3) TWI379835B (is)
UA (1) UA84010C2 (is)
WO (1) WO2004105765A1 (is)

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JO2785B1 (en) * 2003-05-27 2014-03-15 شركة جانسين فارماسوتيكا ان. في Quinazoline derivatives
EP1684762A4 (en) * 2003-11-13 2009-06-17 Ambit Biosciences Corp UREA DERIVATIVES AS MODULATORS OF KINASE
MXPA06007018A (es) * 2003-12-18 2006-08-31 Janssen Pharmaceutica Nv Derivados de 3-ciano-quinolino con actividad anti-proliferativa.
MXPA06007017A (es) 2003-12-18 2006-08-31 Janssen Pharmaceutica Nv Derivados de pirido y pirimidopirimidina como agentes antiproliferativos.
NI200700147A (es) 2004-12-08 2019-05-10 Janssen Pharmaceutica Nv Derivados de quinazolina inhibidores de cinasas dirigidos a multip
JO3088B1 (ar) * 2004-12-08 2017-03-15 Janssen Pharmaceutica Nv مشتقات كوينازولين كبيرة الحلقات و استعمالها بصفتها موانع كينيز متعددة الاهداف
MY169441A (en) 2004-12-08 2019-04-11 Janssen Pharmaceutica Nv 2,4, (4,6) pyrimidine derivatives
DK1854789T3 (da) 2005-02-23 2013-10-21 Shionogi & Co Quinazolinderivat med tyrosin-kinase inhibitorisk aktivitet
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US8778919B2 (en) * 2005-06-30 2014-07-15 Janssen Pharmaceutica Nv Cyclic anilino—pyridinotriazines
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JP2009242240A (ja) * 2006-08-04 2009-10-22 Mebiopharm Co Ltd 含ホウ素キナゾリン誘導体
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MY169791A (en) 2008-10-22 2019-05-15 Array Biopharma Inc Substituted pyrazolo [1,5-a] pyrimidine compounds as trk kinase inhibitors
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MA39822A (fr) 2014-04-03 2018-02-06 Janssen Pharmaceutica Nv Dérivés de pyrimidine bicycle
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CN113354649B (zh) 2014-11-16 2024-12-10 阵列生物制药公司 一种新的晶型
JP6740354B2 (ja) 2015-10-05 2020-08-12 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク オートファジーの流れ及びホスホリパーゼｄ及びタウを含むタンパク質凝集体のクリアランスの活性化剤ならびにタンパク質症の治療方法
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KR20210023984A (ko) 2018-06-25 2021-03-04 앰플릭스 파마슈티컬스, 인크. 헤테로환형 고리 및 아미노기로 치환된 피리딘 유도체
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Also Published As

Publication number Publication date
AU2004243487A1 (en) 2004-12-09
TW201245111A (en) 2012-11-16
MY148633A (en) 2013-05-15
IL172154A0 (en) 2006-04-10
ES2381976T3 (es) 2012-06-04
TW201245160A (en) 2012-11-16
AR045687A1 (es) 2005-11-09
ATE544454T1 (de) 2012-02-15
AU2004243487B2 (en) 2009-12-03
JO2785B1 (en) 2014-03-15
US9273013B2 (en) 2016-03-01
JP2007504276A (ja) 2007-03-01
EP1633365A1 (en) 2006-03-15
HK1176350A1 (zh) 2013-07-26
PA8603801A1 (es) 2004-12-16
TWI468397B (zh) 2015-01-11
KR101143878B1 (ko) 2012-05-24
IL233045A0 (en) 2014-07-31
BRPI0410714A (pt) 2006-06-13
SI1633365T1 (sl) 2012-06-29
JP4887151B2 (ja) 2012-02-29
MXPA05012762A (es) 2006-02-13
US7648975B2 (en) 2010-01-19
EA200501866A1 (ru) 2006-06-30
US20130178624A1 (en) 2013-07-11
CN102718775A (zh) 2012-10-10
CO5640038A2 (es) 2006-05-31
EP1633365B1 (en) 2012-02-08
TWI379835B (en) 2012-12-21
NZ544154A (en) 2009-01-31
IL233046A0 (en) 2014-07-31
HRP20120351T1 (hr) 2012-05-31
IS3030B (is) 2021-06-15
PT1633365E (pt) 2012-05-07
US20100105668A1 (en) 2010-04-29
IL233045B (en) 2018-07-31
CA2525214C (en) 2012-11-27
US20160207938A1 (en) 2016-07-21
NO334209B1 (no) 2014-01-13
NO20056196L (no) 2005-12-28
US8394786B2 (en) 2013-03-12
PL1633365T3 (pl) 2012-07-31
EP2305687A1 (en) 2011-04-06
US20060247237A1 (en) 2006-11-02
CY1113002T1 (el) 2016-04-13
EA009064B1 (ru) 2007-10-26
AR092137A2 (es) 2015-03-25
CA2525214A1 (en) 2004-12-09
KR20060014415A (ko) 2006-02-15
TW200510431A (en) 2005-03-16
BRPI0410714B1 (pt) 2019-09-24
CN102718775B (zh) 2016-02-17
DK1633365T3 (da) 2012-05-14
BRPI0410714B8 (pt) 2021-05-25
WO2004105765A1 (en) 2004-12-09
TWI468372B (zh) 2015-01-11
CL2004001267A1 (es) 2005-04-22
UA84010C2 (en) 2008-09-10

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