IS8129A - Samsetningar paroxetíns og 4-(S)-(4-asetýl-píperasín-1-ýl)-2-(R)-(4-flúor-2-metýl-fenýl)-píperídín-1-karboxýlsýru [1-(R)-(3,5-bis-tríflúormetýl-fenýl)etýl]-metýlamíðs til að meðhöndla þunglyndi og/eða kvíða - Google Patents

Samsetningar paroxetíns og 4-(S)-(4-asetýl-píperasín-1-ýl)-2-(R)-(4-flúor-2-metýl-fenýl)-píperídín-1-karboxýlsýru [1-(R)-(3,5-bis-tríflúormetýl-fenýl)etýl]-metýlamíðs til að meðhöndla þunglyndi og/eða kvíða

Info

Publication number: IS8129A
Authority: IS; Iceland
Prior art keywords: phenyl; methylamide; paroxetine; piperazin; anxiety
Prior art date: 2003-04-17

Application number

IS8129A

Other languages

English (en)

Inventor

Melotto Sergio

Corsi Mauro

Carletti Renzo

Original Assignee

Glaxo Group Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-17

Filing date

2005-11-15

Publication date

2005-11-15

2005-11-15 Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited

2005-11-15 Publication of IS8129A publication Critical patent/IS8129A/is

Links

AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 title 1
208000019901 Anxiety disease Diseases 0.000 title 1
AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 title 1
230000036506 anxiety Effects 0.000 title 1
XGGTZCKQRWXCHW-WMTVXVAQSA-N casopitant Chemical compound C1([C@H]2C[C@H](CCN2C(=O)N(C)[C@H](C)C=2C=C(C=C(C=2)C(F)(F)F)C(F)(F)F)N2CCN(CC2)C(C)=O)=CC=C(F)C=C1C XGGTZCKQRWXCHW-WMTVXVAQSA-N 0.000 title 1
239000000203 mixture Substances 0.000 title 1
229960002296 paroxetine Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

IS8129A 2003-04-17 2005-11-15 Samsetningar paroxetíns og 4-(S)-(4-asetýl-píperasín-1-ýl)-2-(R)-(4-flúor-2-metýl-fenýl)-píperídín-1-karboxýlsýru [1-(R)-(3,5-bis-tríflúormetýl-fenýl)etýl]-metýlamíðs til að meðhöndla þunglyndi og/eða kvíða IS8129A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0308968.7A GB0308968D0 (en)	2003-04-17	2003-04-17	Medicaments
PCT/EP2004/004122 WO2004091616A1 (en)	2003-04-17	2004-04-16	Combinations of paroxetine and 4- (s) - (4-acetyl-piperazin-1-yl) -2- (r)- (4-fluoro-2-methyl-phenyl -piperidine-1-carboxylic acid [1- (r) -(3,5-bis-trifluoromethyl-phenyl) -ethyl] methylamide for treatment of depression and / or anxiety

Publications (1)

Publication Number	Publication Date
IS8129A true IS8129A (is)	2005-11-15

Family

ID=9956996

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IS8128A IS8128A (is)	2003-04-17	2005-11-15	Samsetningar sem fela í sér paroxetín og 2-(S)-(4-flúor-2-metýl-fenýl)-píperasín-1-karboxýlsýru[1-(R)-(3,5-bis-tríflúor-2-metýl-fenýl)-etýl]-metýl-amíð til að meðhöndla þunglyndi og/eða kvíða
IS8129A IS8129A (is)	2003-04-17	2005-11-15	Samsetningar paroxetíns og 4-(S)-(4-asetýl-píperasín-1-ýl)-2-(R)-(4-flúor-2-metýl-fenýl)-píperídín-1-karboxýlsýru [1-(R)-(3,5-bis-tríflúormetýl-fenýl)etýl]-metýlamíðs til að meðhöndla þunglyndi og/eða kvíða

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
IS8128A IS8128A (is)	2003-04-17	2005-11-15	Samsetningar sem fela í sér paroxetín og 2-(S)-(4-flúor-2-metýl-fenýl)-píperasín-1-karboxýlsýru[1-(R)-(3,5-bis-tríflúor-2-metýl-fenýl)-etýl]-metýl-amíð til að meðhöndla þunglyndi og/eða kvíða

Country Status (18)

Country	Link
US (4)	US20060241124A1 (is)
EP (4)	EP1613325A1 (is)
JP (4)	JP2006523651A (is)
KR (2)	KR20060003876A (is)
CN (2)	CN1809355A (is)
AU (2)	AU2004229181A1 (is)
BR (2)	BRPI0409379A (is)
CA (2)	CA2522313A1 (is)
CO (1)	CO5700753A2 (is)
GB (1)	GB0308968D0 (is)
IS (2)	IS8128A (is)
MA (2)	MA27730A1 (is)
MX (2)	MXPA05011063A (is)
NO (2)	NO20055367L (is)
PL (2)	PL377858A1 (is)
RU (2)	RU2005135647A (is)
WO (4)	WO2004091616A1 (is)
ZA (2)	ZA200508067B (is)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0203020D0 (en)	2002-02-08	2002-03-27	Glaxo Group Ltd	Chemical compounds
GB0403149D0 (en) *	2004-02-12	2004-03-17	Glaxo Group Ltd	Medicament
GB0409098D0 (en) *	2004-04-23	2004-05-26	Glaxo Group Ltd	Medicament
GB0426942D0 (en) *	2004-12-08	2005-01-12	Glaxo Group Ltd	Medicament
WO2007012968A2 (en) *	2005-07-29	2007-02-01	Aurobindo Pharma Ltd	Stable dosage form of an antidepressant
GB0621229D0 (en) *	2006-10-20	2006-12-06	Glaxo Group Ltd	Novel use
JP2010516734A (ja)	2007-01-24	2010-05-20	グラクソグループリミテッド	３，５−ジアミノ−６−（２，３−ジクロロフェニル）−１，２，４−トリアジンまたはｒ（−）−２，４−ジアミノ−５−（２，３−ジクロロフェニル）−６−フルオロメチルピリミジンを含む医薬組成物
WO2012175434A1 (en) *	2011-06-20	2012-12-27	Glaxo Group Limited	Pharmaceutical formulations comprising vestipitant
CN103446066B (zh) *	2013-09-16	2014-12-24	南通丝乡丝绸有限公司	帕罗西汀冻干粉针及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL111002A (en) *	1993-09-22	1998-09-24	Glaxo Group Ltd	Piperidine derivatives their preparation and pharmaceutical compositions containing them
US6117855A (en) *	1996-10-07	2000-09-12	Merck Sharp & Dohme Ltd.	Use of a NK-1 receptor antagonist and an antidepressant and/or an anti-anxiety agent
AU735760B2 (en) *	1997-04-24	2001-07-12	Merck Sharp & Dohme Limited	Use of a NK-1 receptor antagonist and an SSRI for treating obesity
GB9923748D0 (en) *	1999-10-07	1999-12-08	Glaxo Group Ltd	Chemical compounds
HK1045308A1 (zh) *	1999-12-17	2002-11-22	Schering Corporation	选择性神经激肽拮抗物
US6436928B1 (en) *	1999-12-17	2002-08-20	Schering Corporation	Selective neurokinin antagonists
PY0117895A (es) *	2000-07-31	2003-11-03	Pfizer Prod Inc	Derivados de imidazol
GB0025354D0 (en) *	2000-10-17	2000-11-29	Glaxo Group Ltd	Chemical compounds
GB0119797D0 (en) *	2001-08-14	2001-10-03	Glaxo Group Ltd	Chemical compounds
JP4459621B2 (ja) *	2001-11-13	2010-04-28	シェーリングコーポレイション	Ｎｋ１アンタゴニスト
GB0203020D0 (en) *	2002-02-08	2002-03-27	Glaxo Group Ltd	Chemical compounds

2003
- 2003-04-17 GB GBGB0308968.7A patent/GB0308968D0/en not_active Ceased
2004
- 2004-04-16 AU AU2004229181A patent/AU2004229181A1/en not_active Abandoned
- 2004-04-16 CA CA002522313A patent/CA2522313A1/en not_active Abandoned
- 2004-04-16 EP EP04727895A patent/EP1613325A1/en not_active Withdrawn
- 2004-04-16 RU RU2005135647/15A patent/RU2005135647A/ru not_active Application Discontinuation
- 2004-04-16 WO PCT/EP2004/004122 patent/WO2004091616A1/en not_active Ceased
- 2004-04-16 CN CNA2004800171620A patent/CN1809355A/zh active Pending
- 2004-04-16 WO PCT/EP2004/004126 patent/WO2004091624A1/en not_active Ceased
- 2004-04-16 BR BRPI0409379-8A patent/BRPI0409379A/pt not_active Application Discontinuation
- 2004-04-16 WO PCT/EP2004/004124 patent/WO2004091617A1/en not_active Ceased
- 2004-04-16 US US10/552,869 patent/US20060241124A1/en not_active Abandoned
- 2004-04-16 MX MXPA05011063A patent/MXPA05011063A/es unknown
- 2004-04-16 US US10/552,870 patent/US20060241143A1/en not_active Abandoned
- 2004-04-16 JP JP2006505187A patent/JP2006523651A/ja active Pending
- 2004-04-16 BR BRPI0409377-1A patent/BRPI0409377A/pt not_active Application Discontinuation
- 2004-04-16 JP JP2006505185A patent/JP2006523649A/ja active Pending
- 2004-04-16 EP EP04739085A patent/EP1615641A1/en not_active Withdrawn
- 2004-04-16 MX MXPA05011064A patent/MXPA05011064A/es unknown
- 2004-04-16 JP JP2006505188A patent/JP2006523652A/ja active Pending
- 2004-04-16 RU RU2005135649/15A patent/RU2005135649A/ru not_active Application Discontinuation
- 2004-04-16 PL PL377858A patent/PL377858A1/pl not_active Application Discontinuation
- 2004-04-16 KR KR1020057019521A patent/KR20060003876A/ko not_active Withdrawn
- 2004-04-16 EP EP04727896A patent/EP1653956A1/en not_active Withdrawn
- 2004-04-16 AU AU2004229179A patent/AU2004229179A1/en not_active Abandoned
- 2004-04-16 WO PCT/EP2004/004121 patent/WO2004091615A1/en not_active Ceased
- 2004-04-16 US US10/552,982 patent/US20060287325A1/en not_active Abandoned
- 2004-04-16 PL PL377857A patent/PL377857A1/pl not_active Application Discontinuation
- 2004-04-16 JP JP2006505186A patent/JP2006523650A/ja active Pending
- 2004-04-16 CN CNA2004800172252A patent/CN1809359A/zh active Pending
- 2004-04-16 EP EP04739086A patent/EP1615642A1/en not_active Withdrawn
- 2004-04-16 CA CA002522311A patent/CA2522311A1/en not_active Abandoned
- 2004-04-16 US US10/552,871 patent/US20060217395A1/en not_active Abandoned
- 2004-04-16 KR KR1020057019520A patent/KR20060003875A/ko not_active Withdrawn
2005
- 2005-10-06 ZA ZA200508067A patent/ZA200508067B/en unknown
- 2005-10-06 ZA ZA200508068A patent/ZA200508068B/en unknown
- 2005-10-14 CO CO05105292A patent/CO5700753A2/es not_active Application Discontinuation
- 2005-10-19 MA MA28561A patent/MA27730A1/fr unknown
- 2005-10-19 MA MA28562A patent/MA27731A1/fr unknown
- 2005-11-14 NO NO20055367A patent/NO20055367L/no not_active Application Discontinuation
- 2005-11-14 NO NO20055368A patent/NO20055368L/no not_active Application Discontinuation
- 2005-11-15 IS IS8128A patent/IS8128A/is unknown
- 2005-11-15 IS IS8129A patent/IS8129A/is unknown

Also Published As

Publication number	Publication date
JP2006523651A (ja)	2006-10-19
KR20060003875A (ko)	2006-01-11
US20060217395A1 (en)	2006-09-28
BRPI0409379A (pt)	2006-04-25
PL377857A1 (pl)	2006-02-20
JP2006523650A (ja)	2006-10-19
MXPA05011064A (es)	2006-04-18
PL377858A1 (pl)	2006-02-20
CA2522311A1 (en)	2004-10-28
CN1809359A (zh)	2006-07-26
WO2004091624A1 (en)	2004-10-28
AU2004229181A1 (en)	2004-10-28
RU2005135647A (ru)	2006-06-10
JP2006523652A (ja)	2006-10-19
BRPI0409377A (pt)	2006-04-25
CO5700753A2 (es)	2006-11-30
IS8128A (is)	2005-11-15
JP2006523649A (ja)	2006-10-19
WO2004091617A1 (en)	2004-10-28
ZA200508067B (en)	2007-02-28
NO20055367L (no)	2005-11-14
KR20060003876A (ko)	2006-01-11
CN1809355A (zh)	2006-07-26
US20060241124A1 (en)	2006-10-26
EP1615641A1 (en)	2006-01-18
ZA200508068B (en)	2007-02-28
EP1613325A1 (en)	2006-01-11
AU2004229179A1 (en)	2004-10-28
WO2004091616A1 (en)	2004-10-28
US20060241143A1 (en)	2006-10-26
GB0308968D0 (en)	2003-05-28
US20060287325A1 (en)	2006-12-21
EP1615642A1 (en)	2006-01-18
MA27731A1 (fr)	2006-01-02
EP1653956A1 (en)	2006-05-10
CA2522313A1 (en)	2004-10-28
NO20055368L (no)	2005-11-14
WO2004091615A1 (en)	2004-10-28
RU2005135649A (ru)	2006-03-20
MXPA05011063A (es)	2005-12-12
MA27730A1 (fr)	2006-01-02

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EA200700117A1 (ru)	2007-06-29	N-замещенные пиперидины и их применение в качестве фармацевтических препаратов
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WO2004046120A3 (en)	2004-08-12	Diaminotriazoles useful as inhibitors of protein kinases
EA200870019A1 (ru)	2008-12-30	Лактамовые соединения и способы их применения
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ATE466580T1 (de)	2010-05-15	Azolylaminoazine als proteinkinasehemmer
ATE433973T1 (de)	2009-07-15	Azolylaminoazine als inhibitoren von proteinkinasen
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MA27192A1 (fr)	2005-01-03	Derives de n- (phenyl(piperidin-2-yl)methyl) benzamide, leur preparation et leur application en therapeutique
ITMI20050262A1 (it)	2006-08-22	Sostanze composizioni e metodi di trattamento dell'alopecia
IL205697A0 (en)	2010-11-30	4(-3-(-2-(phenyl)morpholino)-2-oxopyrrolidin-1-yl)-n-(thiazole-2-yl)benzenesulfon-amide derivatives, compositions comprising the same and uses thereof
DE60329330D1 (de)	2009-10-29	Piperidin- und pyrrolidin-derivate alsantagonisten des histamin-h3-rezeptors
EE200100335A (et)	2002-08-15	4-(aminometüül)piperidiinbensamiidid, vaheühendid, farmatseutiline kompositsioon ja nende valmistamismeetodid
EP1786428A4 (en)	2009-08-05	PDE5 INHIBITOR COMPOSITIONS AND METHOD FOR TREATING DISEASE
DE602005009255D1 (de)	2008-10-02	Amid-prodrug von gemcitabin, zusammensetzungen und verwendung damit
IS8129A (is)	2005-11-15	Samsetningar paroxetíns og 4-(S)-(4-asetýl-píperasín-1-ýl)-2-(R)-(4-flúor-2-metýl-fenýl)-píperídín-1-karboxýlsýru [1-(R)-(3,5-bis-tríflúormetýl-fenýl)etýl]-metýlamíðs til að meðhöndla þunglyndi og/eða kvíða
NO20085052L (no)	2008-12-04	4-((fluorofenoksyl)fenylmetyl)piperidin metansulfonat: anvendelser, synteseprosess og farmasoytiske sammensetninger
ATE471315T1 (de)	2010-07-15	Piperidin- und piperazinacetamide als inhibitoren der 17beta-hydroxysteroiddehydrogenase des typs 3 zur behandlung androgenabhängiger krankheiten
DE602006017574D1 (de)	2010-11-25	Als protein-kinase-inhibitoren nutzbare benzimidazole
ATE435858T1 (de)	2009-07-15	Prodrugs von als erk-proteinkinase-inhibitoren wirkenden pyrrolylpyrimidinen
FR2862968B1 (fr)	2006-08-04	Derives de 4-[(arylmethyl)aminomethyl]piperidine, leur preparation et leur application en therapeutique