MA27731A1 - Combinaison comprenant paroxetine et 2-(s) - (4-fluoro-2-methyl-phenyl) -piperazine-1-acide carboxylique [1- (r)-(3,5-bis-trifluoro-2-methyl-phenyl) -ethyl]-methyl amide destinee au traitement de la depression et/ou de l'anxiete - Google Patents

Combinaison comprenant paroxetine et 2-(s) - (4-fluoro-2-methyl-phenyl) -piperazine-1-acide carboxylique [1- (r)-(3,5-bis-trifluoro-2-methyl-phenyl) -ethyl]-methyl amide destinee au traitement de la depression et/ou de l'anxiete

Info

Publication number
MA27731A1
MA27731A1 MA28562A MA28562A MA27731A1 MA 27731 A1 MA27731 A1 MA 27731A1 MA 28562 A MA28562 A MA 28562A MA 28562 A MA28562 A MA 28562A MA 27731 A1 MA27731 A1 MA 27731A1
Authority
MA
Morocco
Prior art keywords
methyl
phenyl
fluoro
bis
ethyl
Prior art date
Application number
MA28562A
Other languages
English (en)
Inventor
Melotto Sergio
Corsi Mauro
Carletti Renzo
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MA27731A1 publication Critical patent/MA27731A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Associations comprenant de la paroxétine et du [1-(R)-(3,5-bis-trifluoro-2-méthylphényl)-éthyl]-méthylamide d'acide 2-(S)-(4-fluoro-2-méthylphényl)-pipérazine-1-carboxylique pour le traitement de la dépression et/ou de l'anxiété La présente invention concerne des associations thérapeutiques comprenant de la paroxétine ou ses sels ou produits de solvatation physiologiquement acceptables et du [1-(R)-(3, 5-bis-trifluorométhyl-phényl)-éthyl]-méthylamide d'acide 2-(S)-(4-fluoro-2-méthyl-phényl)-pipérazine-1-carboxylique ou ses sels ou produits de solvatation physiologiquement acceptables, des compositions pharmaceutiques contenant lesdites associations, et leur utilisation dans le traitement de la dépression et/ou de l'anxiété.
MA28562A 2003-04-17 2005-10-19 Combinaison comprenant paroxetine et 2-(s) - (4-fluoro-2-methyl-phenyl) -piperazine-1-acide carboxylique [1- (r)-(3,5-bis-trifluoro-2-methyl-phenyl) -ethyl]-methyl amide destinee au traitement de la depression et/ou de l'anxiete MA27731A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0308968.7A GB0308968D0 (en) 2003-04-17 2003-04-17 Medicaments

Publications (1)

Publication Number Publication Date
MA27731A1 true MA27731A1 (fr) 2006-01-02

Family

ID=9956996

Family Applications (2)

Application Number Title Priority Date Filing Date
MA28561A MA27730A1 (fr) 2003-04-17 2005-10-19 Combinaisons de paroxetine et de 4-(s)-(4-acetyl-piperazin-1-yl-)-2-(r)-(4-fluoro-2-methyl-phenyl)-piperidine-1-acide carboxylique[1-(r)-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-methylamide utilisees dans le traitement de la depression et/ou de l'anxiete
MA28562A MA27731A1 (fr) 2003-04-17 2005-10-19 Combinaison comprenant paroxetine et 2-(s) - (4-fluoro-2-methyl-phenyl) -piperazine-1-acide carboxylique [1- (r)-(3,5-bis-trifluoro-2-methyl-phenyl) -ethyl]-methyl amide destinee au traitement de la depression et/ou de l'anxiete

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MA28561A MA27730A1 (fr) 2003-04-17 2005-10-19 Combinaisons de paroxetine et de 4-(s)-(4-acetyl-piperazin-1-yl-)-2-(r)-(4-fluoro-2-methyl-phenyl)-piperidine-1-acide carboxylique[1-(r)-(3,5-bis-trifluoromethyl-phenyl)-ethyl]-methylamide utilisees dans le traitement de la depression et/ou de l'anxiete

Country Status (18)

Country Link
US (4) US20060241124A1 (fr)
EP (4) EP1613325A1 (fr)
JP (4) JP2006523651A (fr)
KR (2) KR20060003876A (fr)
CN (2) CN1809355A (fr)
AU (2) AU2004229181A1 (fr)
BR (2) BRPI0409379A (fr)
CA (2) CA2522313A1 (fr)
CO (1) CO5700753A2 (fr)
GB (1) GB0308968D0 (fr)
IS (2) IS8128A (fr)
MA (2) MA27730A1 (fr)
MX (2) MXPA05011063A (fr)
NO (2) NO20055367L (fr)
PL (2) PL377858A1 (fr)
RU (2) RU2005135647A (fr)
WO (4) WO2004091616A1 (fr)
ZA (2) ZA200508067B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0203020D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
GB0403149D0 (en) * 2004-02-12 2004-03-17 Glaxo Group Ltd Medicament
GB0409098D0 (en) * 2004-04-23 2004-05-26 Glaxo Group Ltd Medicament
GB0426942D0 (en) * 2004-12-08 2005-01-12 Glaxo Group Ltd Medicament
WO2007012968A2 (fr) * 2005-07-29 2007-02-01 Aurobindo Pharma Ltd Forme dosifee stable d'un antidepresseur
GB0621229D0 (en) * 2006-10-20 2006-12-06 Glaxo Group Ltd Novel use
JP2010516734A (ja) 2007-01-24 2010-05-20 グラクソ グループ リミテッド ３，５−ジアミノ−６−（２，３−ジクロロフェニル）−１，２，４−トリアジンまたはｒ（−）−２，４−ジアミノ−５−（２，３−ジクロロフェニル）−６−フルオロメチルピリミジンを含む医薬組成物
WO2012175434A1 (fr) * 2011-06-20 2012-12-27 Glaxo Group Limited Formulations pharmaceutiques comprenant du vestipitant
CN103446066B (zh) * 2013-09-16 2014-12-24 南通丝乡丝绸有限公司 帕罗西汀冻干粉针及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL111002A (en) * 1993-09-22 1998-09-24 Glaxo Group Ltd Piperidine derivatives their preparation and pharmaceutical compositions containing them
US6117855A (en) * 1996-10-07 2000-09-12 Merck Sharp & Dohme Ltd. Use of a NK-1 receptor antagonist and an antidepressant and/or an anti-anxiety agent
AU735760B2 (en) * 1997-04-24 2001-07-12 Merck Sharp & Dohme Limited Use of a NK-1 receptor antagonist and an SSRI for treating obesity
GB9923748D0 (en) * 1999-10-07 1999-12-08 Glaxo Group Ltd Chemical compounds
HK1045308A1 (zh) * 1999-12-17 2002-11-22 Schering Corporation 选择性神经激肽拮抗物
US6436928B1 (en) * 1999-12-17 2002-08-20 Schering Corporation Selective neurokinin antagonists
PY0117895A (es) * 2000-07-31 2003-11-03 Pfizer Prod Inc Derivados de imidazol
GB0025354D0 (en) * 2000-10-17 2000-11-29 Glaxo Group Ltd Chemical compounds
GB0119797D0 (en) * 2001-08-14 2001-10-03 Glaxo Group Ltd Chemical compounds
JP4459621B2 (ja) * 2001-11-13 2010-04-28 シェーリング コーポレイション Ｎｋ１アンタゴニスト
GB0203020D0 (en) * 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
JP2006523651A (ja) 2006-10-19
KR20060003875A (ko) 2006-01-11
US20060217395A1 (en) 2006-09-28
BRPI0409379A (pt) 2006-04-25
PL377857A1 (pl) 2006-02-20
JP2006523650A (ja) 2006-10-19
MXPA05011064A (es) 2006-04-18
PL377858A1 (pl) 2006-02-20
CA2522311A1 (fr) 2004-10-28
CN1809359A (zh) 2006-07-26
WO2004091624A1 (fr) 2004-10-28
AU2004229181A1 (en) 2004-10-28
RU2005135647A (ru) 2006-06-10
JP2006523652A (ja) 2006-10-19
BRPI0409377A (pt) 2006-04-25
CO5700753A2 (es) 2006-11-30
IS8128A (is) 2005-11-15
JP2006523649A (ja) 2006-10-19
IS8129A (is) 2005-11-15
WO2004091617A1 (fr) 2004-10-28
ZA200508067B (en) 2007-02-28
NO20055367L (no) 2005-11-14
KR20060003876A (ko) 2006-01-11
CN1809355A (zh) 2006-07-26
US20060241124A1 (en) 2006-10-26
EP1615641A1 (fr) 2006-01-18
ZA200508068B (en) 2007-02-28
EP1613325A1 (fr) 2006-01-11
AU2004229179A1 (en) 2004-10-28
WO2004091616A1 (fr) 2004-10-28
US20060241143A1 (en) 2006-10-26
GB0308968D0 (en) 2003-05-28
US20060287325A1 (en) 2006-12-21
EP1615642A1 (fr) 2006-01-18
EP1653956A1 (fr) 2006-05-10
CA2522313A1 (fr) 2004-10-28
NO20055368L (no) 2005-11-14
WO2004091615A1 (fr) 2004-10-28
RU2005135649A (ru) 2006-03-20
MXPA05011063A (es) 2005-12-12
MA27730A1 (fr) 2006-01-02

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