IS8217A - Bætt framleiðsla rósúvastatínkalsíumsalts - Google Patents

Bætt framleiðsla rósúvastatínkalsíumsalts

Info

Publication number: IS8217A
Authority: IS; Iceland
Prior art keywords: calcium salt; improved production; rosuvastatin calcium; rosuvastatin; production
Prior art date: 2003-06-05

Application number

IS8217A

Other languages

English (en)

Other versions

IS2751B (is

Inventor

Norman Crabb Jeffrey

Horbury John

Philip Taylor Nigel

Original Assignee

Astrazeneca Uk Limited

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-05

Filing date

2006-01-02

Publication date

2006-01-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33512687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS8217(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-01-02 Application filed by Astrazeneca Uk Limited filed Critical Astrazeneca Uk Limited

2006-01-02 Publication of IS8217A publication Critical patent/IS8217A/is

2011-09-15 Publication of IS2751B publication Critical patent/IS2751B/is

Links

LALFOYNTGMUKGG-BGRFNVSISA-L rosuvastatin calcium Chemical class [Ca+2].CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O.CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O LALFOYNTGMUKGG-BGRFNVSISA-L 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Obesity (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IS8217A 2003-06-05 2006-01-02 Bætt@framleiðsla@rósúvastatínkalsíumsalts IS2751B (is)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB0312896.4A GB0312896D0 (en)	2003-06-05	2003-06-05	Chemical process
GBGB0324793.9A GB0324793D0 (en)	2003-06-05	2003-10-24	Chemical process
PCT/GB2004/002373 WO2004108691A1 (en)	2003-06-05	2004-06-03	Improved production of rosuvastatin calcium salt

Publications (2)

Publication Number	Publication Date
IS8217A true IS8217A (is)	2006-01-02
IS2751B IS2751B (is)	2011-09-15

Family

ID=33512687

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS8217A IS2751B (is)	2003-06-05	2006-01-02	Bætt@framleiðsla@rósúvastatínkalsíumsalts

Country Status (25)

Country	Link
US (1)	US8063213B2 (is)
EP (1)	EP1633727B1 (is)
JP (1)	JP4651615B2 (is)
KR (1)	KR101099934B1 (is)
CN (1)	CN100422157C (is)
AR (1)	AR044773A1 (is)
AT (1)	ATE464297T1 (is)
AU (1)	AU2004245291B2 (is)
BR (1)	BRPI0410922B8 (is)
CA (1)	CA2527314C (is)
CO (1)	CO5640116A2 (is)
DE (1)	DE602004026576D1 (is)
ES (1)	ES2341858T3 (is)
GB (2)	GB0312896D0 (is)
IL (1)	IL172075A (is)
IS (1)	IS2751B (is)
MX (1)	MXPA05013128A (is)
MY (1)	MY140820A (is)
NO (1)	NO332971B1 (is)
NZ (1)	NZ543962A (is)
RU (1)	RU2361864C2 (is)
SA (1)	SA04250223B1 (is)
TW (1)	TWI341310B (is)
UY (1)	UY28341A1 (is)
WO (1)	WO2004108691A1 (is)

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KR101060215B1 (ko)	2002-12-16	2011-08-29	아스트라제네카 유케이 리미티드	피리미딘 화합물의 제조 방법
GB0312896D0 (en)	2003-06-05	2003-07-09	Astrazeneca Ab	Chemical process
UY28501A1 (es)	2003-09-10	2005-04-29	Astrazeneca Uk Ltd	Compuestos químicos
GB0322552D0 (en)	2003-09-26	2003-10-29	Astrazeneca Uk Ltd	Therapeutic treatment
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US7851624B2 (en)	2003-12-24	2010-12-14	Teva Pharamaceutical Industries Ltd.	Triol form of rosuvastatin and synthesis of rosuvastatin
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GB0428328D0 (en)	2004-12-24	2005-02-02	Astrazeneca Uk Ltd	Chemical process
TWI353981B (en) *	2005-02-22	2011-12-11	Teva Pharma	Preparation of rosuvastatin
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EP1919880A2 (en) *	2005-08-16	2008-05-14	Teva Pharmaceutical Industries Ltd.	Rosuvastatin calcium with a low salt by-product content
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HU227696B1 (en) *	2006-04-13	2011-12-28	Egyt Gyogyszervegyeszeti Gyar	Zinc salt of rosuvastatin, process for its preparation and pharmaceutical compositions containing it
WO2007125547A2 (en)	2006-05-03	2007-11-08	Manne Satyanarayana Reddy	Novel process for statins and its pharmaceutically acceptable salts thereof
US8404841B2 (en)	2006-10-09	2013-03-26	Msn Laboratories Limited	Process for the preparation of statins and their pharmaceutically acceptable salts thereof
TW200831469A (en) *	2006-12-01	2008-08-01	Astrazeneca Uk Ltd	Chemical process
HU230981B1 (hu) *	2007-10-12	2019-08-28	Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság	Eljárás rosuvastatin só előállítására
WO2009143776A1 (zh)	2008-05-27	2009-12-03	常州制药厂有限公司	瑞舒伐他汀钙盐的制备方法及其中间体
HUE035402T2 (en)	2008-06-27	2018-05-02	Krka Tovarna Zdravil D D Novo Mesto	Pharmaceutical composition containing statin
EP2138165A1 (en)	2008-06-27	2009-12-30	KRKA, tovarna zdravil, d.d., Novo mesto	Pharmaceutical composition comprising a statin
EP2334667A4 (en) *	2008-09-09	2011-10-26	Biocon Ltd	PROCESS FOR THE PREPARATION OF ACETONIDE ROSUVASTATIN CALCIUM
SI2373609T1 (sl)	2008-12-19	2013-12-31	Krka, D.D., Novo Mesto	Uporaba amfifilnih spojin za kontrolirano kristalizacijo statinov in intermediatov statinov
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US8987444B2 (en)	2010-01-18	2015-03-24	Msn Laboratories Private Limited	Process for the preparation of amide intermediates and their use thereof
CA2796964A1 (en)	2010-04-23	2011-10-27	Ranbaxy Laboratories Limited	Intermediates for the preparation of hmg-coa reductase inhibitors
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CN105753834B (zh) *	2016-03-25	2018-08-21	河南师范大学	一种瑞舒伐他汀钙关键手性中间体的合成方法

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TW200831469A (en)	2006-12-01	2008-08-01	Astrazeneca Uk Ltd	Chemical process

2003
- 2003-06-05 GB GBGB0312896.4A patent/GB0312896D0/en not_active Ceased
- 2003-10-24 GB GBGB0324793.9A patent/GB0324793D0/en not_active Ceased
2004
- 2004-05-24 TW TW093114667A patent/TWI341310B/zh not_active IP Right Cessation
- 2004-06-02 UY UY28341A patent/UY28341A1/es not_active Application Discontinuation
- 2004-06-03 US US10/558,390 patent/US8063213B2/en active Active
- 2004-06-03 CN CNB2004800154822A patent/CN100422157C/zh not_active Expired - Lifetime
- 2004-06-03 KR KR1020057023329A patent/KR101099934B1/ko not_active Expired - Lifetime
- 2004-06-03 AT AT04735910T patent/ATE464297T1/de not_active IP Right Cessation
- 2004-06-03 BR BRPI0410922A patent/BRPI0410922B8/pt active IP Right Grant
- 2004-06-03 ES ES04735910T patent/ES2341858T3/es not_active Expired - Lifetime
- 2004-06-03 NZ NZ543962A patent/NZ543962A/en not_active IP Right Cessation
- 2004-06-03 MX MXPA05013128A patent/MXPA05013128A/es active IP Right Grant
- 2004-06-03 MY MYPI20042138A patent/MY140820A/en unknown
- 2004-06-03 RU RU2005138370/04A patent/RU2361864C2/ru active
- 2004-06-03 CA CA2527314A patent/CA2527314C/en not_active Expired - Fee Related
- 2004-06-03 JP JP2006508394A patent/JP4651615B2/ja not_active Expired - Lifetime
- 2004-06-03 EP EP04735910A patent/EP1633727B1/en not_active Expired - Lifetime
- 2004-06-03 DE DE602004026576T patent/DE602004026576D1/de not_active Expired - Lifetime
- 2004-06-03 WO PCT/GB2004/002373 patent/WO2004108691A1/en not_active Ceased
- 2004-06-03 AU AU2004245291A patent/AU2004245291B2/en not_active Expired
- 2004-06-04 AR ARP040101944A patent/AR044773A1/es unknown
- 2004-07-14 SA SA04250223A patent/SA04250223B1/ar unknown
2005
- 2005-11-21 IL IL172075A patent/IL172075A/en active IP Right Grant
- 2005-12-02 CO CO05122683A patent/CO5640116A2/es unknown
- 2005-12-05 NO NO20055730A patent/NO332971B1/no not_active IP Right Cessation
2006
- 2006-01-02 IS IS8217A patent/IS2751B/is unknown

Also Published As

Publication number	Publication date
IS2751B (is)	2011-09-15
BRPI0410922B8 (pt)	2021-05-25
EP1633727A1 (en)	2006-03-15
AU2004245291B2 (en)	2008-02-14
AR044773A1 (es)	2005-10-05
US8063213B2 (en)	2011-11-22
JP4651615B2 (ja)	2011-03-16
KR20060017848A (ko)	2006-02-27
ES2341858T3 (es)	2010-06-29
EP1633727B1 (en)	2010-04-14
BRPI0410922A (pt)	2006-06-27
MXPA05013128A (es)	2006-03-16
NO332971B1 (no)	2013-02-11
KR101099934B1 (ko)	2011-12-28
CA2527314C (en)	2012-02-21
IL172075A (en)	2011-06-30
GB0324793D0 (en)	2003-11-26
JP2006526602A (ja)	2006-11-24
TW200510337A (en)	2005-03-16
CN100422157C (zh)	2008-10-01
NZ543962A (en)	2008-09-26
SA04250223B1 (ar)	2008-12-23
UY28341A1 (es)	2005-01-31
HK1087405A1 (en)	2006-10-13
NO20055730L (no)	2005-12-27
RU2361864C2 (ru)	2009-07-20
MY140820A (en)	2010-01-29
CA2527314A1 (en)	2004-12-16
ATE464297T1 (de)	2010-04-15
TWI341310B (en)	2011-05-01
CN1798741A (zh)	2006-07-05
DE602004026576D1 (de)	2010-05-27
CO5640116A2 (es)	2006-05-31
RU2005138370A (ru)	2006-07-10
AU2004245291A1 (en)	2004-12-16
GB0312896D0 (en)	2003-07-09
US20080221323A1 (en)	2008-09-11
WO2004108691A1 (en)	2004-12-16
NO20055730D0 (no)	2005-12-05
BRPI0410922B1 (pt)	2016-02-23

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