IT1099026B - Composti ad azione analgesica comprendenti derivati di azacicloalcani - Google Patents

Composti ad azione analgesica comprendenti derivati di azacicloalcani

Info

Publication number: IT1099026B
Authority: IT; Italy
Prior art keywords: azacyclalkane; derivatives; compounds including; analgesic action; action compounds
Prior art date: 1977-09-13

Application number

IT27557/78A

Other languages

English (en)

Italian (it)

Other versions

IT7827557A0 (it

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-09-13

Filing date

1978-09-12

Publication date

1985-09-18

1978-09-12 Application filed by Pfizer filed Critical Pfizer

1978-09-12 Publication of IT7827557A0 publication Critical patent/IT7827557A0/it

1985-09-18 Application granted granted Critical

1985-09-18 Publication of IT1099026B publication Critical patent/IT1099026B/it

Links

230000000202 analgesic effect Effects 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/42—Oxygen atoms attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Epoxy Compounds (AREA)

IT27557/78A 1977-09-13 1978-09-12 Composti ad azione analgesica comprendenti derivati di azacicloalcani IT1099026B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/832,869 US4147872A (en)	1977-09-13	1977-09-13	3-[2-Hydroxy-4-(substituted)-phenyl]azacycloalkanes and derivatives thereof as analgesic agents and intermediates therefor

Publications (2)

Publication Number	Publication Date
IT7827557A0 IT7827557A0 (it)	1978-09-12
IT1099026B true IT1099026B (it)	1985-09-18

Family

ID=25262819

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT27557/78A IT1099026B (it)	1977-09-13	1978-09-12	Composti ad azione analgesica comprendenti derivati di azacicloalcani

Country Status (23)

Country	Link
US (1)	US4147872A (fr)
JP (5)	JPS5935397B2 (fr)
AR (2)	AR222019A1 (fr)
AT (1)	AT368753B (fr)
AU (1)	AU507953B1 (fr)
BE (1)	BE870403A (fr)
CA (1)	CA1113463A (fr)
CH (1)	CH638187A5 (fr)
DE (1)	DE2839883A1 (fr)
DK (1)	DK401078A (fr)
ES (2)	ES473287A1 (fr)
FI (1)	FI66173C (fr)
FR (4)	FR2401913A1 (fr)
GB (1)	GB2004548B (fr)
IE (1)	IE47717B1 (fr)
IL (1)	IL55555A (fr)
IT (1)	IT1099026B (fr)
LU (1)	LU80219A1 (fr)
NL (1)	NL7809272A (fr)
PH (1)	PH15372A (fr)
PT (1)	PT68542A (fr)
SE (2)	SE7809606L (fr)
YU (1)	YU215678A (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4241071A (en) *	1977-01-27	1980-12-23	American Hoechst Corporation	Antidepressant (α-phenyl-2-tolyl)azacycloalkanes
FI792076A7 (fi) *	1978-07-05	1981-01-01	Ciba Geigy Ag	Menetelmä uusien fenyylipiperidiinijohdannaisten valmistamiseksi.
US4312876A (en) *	1979-02-23	1982-01-26	Hoechst-Roussel Pharmaceuticals Incorporated	Antidepressive and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines
US4302590A (en) *	1979-02-23	1981-11-24	Hoechst-Roussel Pharmaceuticals, Inc.	Intermediates for the preparation of 4-aryloxy-3-phenylpiperidines
US4216218A (en) *	1979-02-23	1980-08-05	American Hoechst Corporation	Antidepressant and analgesic 4-aryloxy- and 4-arylthio-3-phenylpiperidines
ZA821888B (en) *	1981-04-01	1983-02-23	Haessle Ab	Novel phenyl-piperidines
US4709016A (en) *	1982-02-01	1987-11-24	Northeastern University	Molecular analytical release tags and their use in chemical analysis
US4529732A (en) *	1983-03-14	1985-07-16	Pfizer Inc.	2-[2-Hydroxy-4-(substituted)phenyl]piperidines
FI864570A0 (fi) *	1986-11-11	1986-11-11	Farmos Oy	Terapeutiskt anvaendbar foerening.
CA2450073C (fr)	2001-07-25	2017-08-29	Biomarin Pharmaceutical Inc.	Compositions et procedes de modulation du transport a travers la barriere hematho-encephalique
WO2004017920A2 (fr) *	2002-08-23	2004-03-04	University Of Connecticut	Nouveaux cannabinoides biphenyle et de type biphenyle
DE102004036349A1 (de) *	2004-07-27	2006-03-23	Grünenthal GmbH	Substituierte 3-Phenylpiperidin-Derivate
EP2671508B1 (fr)	2005-04-28	2020-09-16	Proteus Digital Health, Inc.	Système pharma-informatique
JP2010503710A (ja)	2006-09-18	2010-02-04	ラプトールファーマシューティカルインコーポレイテッド	受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
ES2919563T3 (es)	2009-02-20	2022-07-27	Enhanx Biopharm Inc	Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko)	2009-05-06	2018-10-19	라보라토리 스킨 케어, 인크.	활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates
CA2900309A1 (fr)	2013-02-14	2014-08-21	Galderma Research & Development	Procede de synthese de 4-piperidin-4-yl-benzene-1,3-diol et de ses sels et nouveau compose 4-(2,4-dihydroxy-phenyl)-4-hydroxy-piperidine-1-carboxylate de tert-butyle

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2310761A1 (fr) *	1975-05-16	1976-12-10	Roussel Uclaf	Nouveaux derives de la phenyl-piperidine et leurs sels, procede de preparation et application a titre de medicaments

1977
- 1977-09-13 US US05/832,869 patent/US4147872A/en not_active Expired - Lifetime
1978
- 1978-09-12 IE IE1837/78A patent/IE47717B1/en unknown
- 1978-09-12 YU YU02156/78A patent/YU215678A/xx unknown
- 1978-09-12 NL NL7809272A patent/NL7809272A/xx not_active Application Discontinuation
- 1978-09-12 DK DK401078A patent/DK401078A/da not_active Application Discontinuation
- 1978-09-12 FI FI782793A patent/FI66173C/fi not_active IP Right Cessation
- 1978-09-12 IL IL55555A patent/IL55555A/xx unknown
- 1978-09-12 LU LU80219A patent/LU80219A1/fr unknown
- 1978-09-12 JP JP53112171A patent/JPS5935397B2/ja not_active Expired
- 1978-09-12 FR FR7826195A patent/FR2401913A1/fr active Granted
- 1978-09-12 SE SE7809606A patent/SE7809606L/xx unknown
- 1978-09-12 BE BE190418A patent/BE870403A/fr not_active IP Right Cessation
- 1978-09-12 AT AT0658078A patent/AT368753B/de not_active IP Right Cessation
- 1978-09-12 ES ES473287A patent/ES473287A1/es not_active Expired
- 1978-09-12 AU AU39778/78A patent/AU507953B1/en not_active Expired
- 1978-09-12 IT IT27557/78A patent/IT1099026B/it active
- 1978-09-12 CA CA311,113A patent/CA1113463A/fr not_active Expired
- 1978-09-12 GB GB7836419A patent/GB2004548B/en not_active Expired
- 1978-09-12 PT PT68542A patent/PT68542A/pt unknown
- 1978-09-13 AR AR273692A patent/AR222019A1/es active
- 1978-09-13 DE DE19782839883 patent/DE2839883A1/de not_active Withdrawn
- 1978-09-13 CH CH955778A patent/CH638187A5/fr not_active IP Right Cessation
- 1978-09-13 PH PH21600A patent/PH15372A/en unknown
- 1978-12-13 JP JP15404678A patent/JPS5492973A/ja active Pending
- 1978-12-13 JP JP15404778A patent/JPS5538365A/ja active Pending
- 1978-12-13 JP JP15404578A patent/JPS5495577A/ja active Granted
- 1978-12-13 JP JP15404878A patent/JPS5538366A/ja active Pending
1979
- 1979-02-28 FR FR7905185A patent/FR2412529A1/fr active Granted
- 1979-02-28 FR FR7905183A patent/FR2412531A1/fr active Granted
- 1979-02-28 FR FR7905184A patent/FR2412530A1/fr active Granted
- 1979-05-02 ES ES480151A patent/ES480151A1/es not_active Expired
- 1979-07-10 AR AR277236A patent/AR220567A1/es active
1983
- 1983-10-03 SE SE8305422A patent/SE8305422D0/xx not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES480151A1 (es)	1980-04-01
ATA658078A (de)	1982-03-15
IL55555A0 (en)	1978-12-17
FR2401913A1 (fr)	1979-03-30
JPS5935397B2 (ja)	1984-08-28
PH15372A (en)	1982-12-10
AU507953B1 (en)	1980-03-06
YU215678A (en)	1983-06-30
FR2401913B1 (fr)	1983-01-21
AR220567A1 (es)	1980-11-14
FR2412529A1 (fr)	1979-07-20
CH638187A5 (fr)	1983-09-15
JPS5463086A (en)	1979-05-21
IL55555A (en)	1982-08-31
JPS5640155B2 (fr)	1981-09-18
JPS5538365A (en)	1980-03-17
IE781837L (en)	1979-03-13
FR2412531A1 (fr)	1979-07-20
FR2412530B1 (fr)	1982-11-12
FI782793A7 (fi)	1979-03-14
NL7809272A (nl)	1979-03-15
JPS5492973A (en)	1979-07-23
BE870403A (fr)	1979-03-12
IE47717B1 (en)	1984-05-30
AR222019A1 (es)	1981-04-15
IT7827557A0 (it)	1978-09-12
PT68542A (en)	1978-10-01
FR2412530A1 (fr)	1979-07-20
US4147872A (en)	1979-04-03
AT368753B (de)	1982-11-10
SE8305422L (sv)	1983-10-03
LU80219A1 (fr)	1980-04-21
FR2412531B1 (fr)	1983-01-14
JPS5495577A (en)	1979-07-28
DE2839883A1 (de)	1979-03-15
JPS5538366A (en)	1980-03-17
GB2004548A (en)	1979-04-04
CA1113463A (fr)	1981-12-01
FI66173B (fi)	1984-05-31
SE7809606L (sv)	1979-03-14
DK401078A (da)	1979-03-14
GB2004548B (en)	1982-03-24
FR2412529B1 (fr)	1983-01-14
FI66173C (fi)	1984-09-10
SE8305422D0 (sv)	1983-10-03
ES473287A1 (es)	1980-03-01

Publication	Publication Date	Title
IT1105411B (it)	1985-11-04	Derivati di ciclosano
IT1098858B (it)	1985-09-18	Derivati di immidazoli
IT1098276B (it)	1985-09-07	Derivati di trifenilalcheni
IT1148727B (it)	1986-12-03	Derivati di 4-fenil-ftalazine ad azione terapeutica
IT1094944B (it)	1985-08-10	Derivati di ftalazina
IT1101613B (it)	1985-10-07	Derivati di 2,6-diamminonebularine ad azione farmacolosica
SE7711581L (sv)	1979-04-15	Xantin-derivat
IT1140976B (it)	1986-10-10	Derivati di alchil-chetoesopiranosidi
DK543178A (da)	1979-06-02	Thiodydantoinderivater
IT7827557A0 (it)	1978-09-12	Composti ad azione analgesica comprendenti derivati di azacicloalcani.
SE7800982L (sv)	1978-07-28	Meta-sulfonamido-bensamid-derivat
SE7809373L (sv)	1979-03-07	Farmaceutiskt anvendbara 5-hydroxi-1h-imidazol-4-karboxamidderivat
FI782971A7 (fi)	1979-04-04	Analgetiska foereningar
IT1095472B (it)	1985-08-10	Derivati di immidazolo
IT1095377B (it)	1985-08-10	Composizione farmaceutica
IT1096276B (it)	1985-08-26	Derivati di benzimmidazolo
IT1092333B (it)	1985-07-06	Derivati di ossadiazol-pirimidine
IT1111174B (it)	1986-01-13	Derivati di piridazione
SE7806441L (sv)	1978-12-04	Lekemedelskomposition
IT1099358B (it)	1985-09-18	Composti lattamici ad azione ansiolitica
IT7822985A0 (it)	1978-05-03	Derivati di amminoalcoli.
FI780343A7 (fi)	1978-08-05	Oxadiazolopyrimidinderivat
IT1095493B (it)	1985-08-10	Derivati di chinazoline
IT1096294B (it)	1985-08-26	Derivati di fenilglicina
IT1089247B (it)	1985-06-18	5-6-di idro-prostaciclina derivati