IT1099358B - Composti lattamici ad azione ansiolitica - Google Patents

Composti lattamici ad azione ansiolitica

Info

Publication number
IT1099358B
IT1099358B IT28617/78A IT2861778A IT1099358B IT 1099358 B IT1099358 B IT 1099358B IT 28617/78 A IT28617/78 A IT 28617/78A IT 2861778 A IT2861778 A IT 2861778A IT 1099358 B IT1099358 B IT 1099358B
Authority
IT
Italy
Prior art keywords
ansiolytic
lactamic
compounds
action
lactamic compounds
Prior art date
Application number
IT28617/78A
Other languages
English (en)
Other versions
IT7828617A0 (it
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12224977A external-priority patent/JPS5455562A/ja
Priority claimed from JP8753378A external-priority patent/JPS5515432A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of IT7828617A0 publication Critical patent/IT7828617A0/it
Application granted granted Critical
Publication of IT1099358B publication Critical patent/IT1099358B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
IT28617/78A 1977-10-11 1978-10-10 Composti lattamici ad azione ansiolitica IT1099358B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12224977A JPS5455562A (en) 1977-10-11 1977-10-11 Lactam compound
JP8753378A JPS5515432A (en) 1978-07-17 1978-07-17 Lactam compound

Publications (2)

Publication Number Publication Date
IT7828617A0 IT7828617A0 (it) 1978-10-10
IT1099358B true IT1099358B (it) 1985-09-18

Family

ID=26428792

Family Applications (1)

Application Number Title Priority Date Filing Date
IT28617/78A IT1099358B (it) 1977-10-11 1978-10-10 Composti lattamici ad azione ansiolitica

Country Status (8)

Country Link
US (1) US4198514A (it)
EP (1) EP0001601B1 (it)
AU (1) AU518986B2 (it)
CA (1) CA1102338A (it)
DE (1) DE2861210D1 (it)
DK (1) DK439878A (it)
IT (1) IT1099358B (it)
NO (1) NO150041C (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549053B1 (fr) * 1983-07-12 1985-12-27 Sanofi Sa Nouveaux derives de la pyrrolidine actifs sur le systeme nerveux central, leur procede de preparation, les medicaments en contenant
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
US4584313A (en) * 1984-05-07 1986-04-22 Warner-Lambert Company (Substituted-phenyl)-5-oxo-2-pyrrolidinepropanoic acids and esters thereof, and use for reversing electroconvulsive shock-induced amnesia
FR2587339B1 (fr) * 1985-04-04 1988-08-05 Hoechst Lab Nouveaux medicaments constitues par des derives-2,3 ou -3,4 diphenyles des esters g-nitriles ou leurs produits de cyclisation et procedes pour les preparer
JPH066571B2 (ja) * 1985-05-09 1994-01-26 エーザイ株式会社 ２−ピロリドン誘導体
DE3823299A1 (de) * 1988-07-07 1990-01-11 Schering Ag Substituierte phenyl-pyrrolidin-2-one, -oxazolidin-2-one und -imidazolidin-2-one, ihre herstellung sowie verwendung in arzneimitteln
US5776959A (en) * 1995-06-05 1998-07-07 Washington University Anticonvulsant and anxiolytic lactam and thiolactam derivatives
GB9515411D0 (en) * 1995-07-27 1995-09-27 Pharmacia Spa N-(4-substituted-benzyl)-2-aminolactam derivatives
WO2012059797A1 (en) * 2010-11-04 2012-05-10 Lupin Limited Process for synthesis of (s) - pregabalin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3301759A (en) * 1965-05-26 1967-01-31 Robins Co Inc A H Analeptic compositions and method
US3317390A (en) * 1965-07-27 1967-05-02 American Cyanamid Co Compositions having cns depressant activity
GB1350582A (en) * 1970-07-24 1974-04-18 Ucb Sa Cerivatives of 2-pyrrolidinone
US3814771A (en) * 1970-11-19 1974-06-04 T Shen 5-phenyl-2-piperidones and 5-phenyl-2-thiopiperidones
JPS514041Y2 (it) * 1971-06-02 1976-02-04
JPS5821622B2 (ja) * 1973-02-28 1983-05-02 ウェルファイド株式会社 ピロリジンメタノ−ル ノ セイゾウホウ
LU75478A1 (it) * 1976-07-28 1978-02-08

Also Published As

Publication number Publication date
DK439878A (da) 1979-04-12
DE2861210D1 (en) 1981-12-24
US4198514A (en) 1980-04-15
AU4024278A (en) 1980-04-03
AU518986B2 (en) 1981-10-29
NO783420L (no) 1979-04-17
NO150041C (no) 1984-08-15
IT7828617A0 (it) 1978-10-10
EP0001601A1 (en) 1979-05-02
CA1102338A (en) 1981-06-02
NO150041B (no) 1984-04-30
EP0001601B1 (en) 1981-10-21

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