IT1104165B - Nuova applicazione terapeutica della carnitina della acetil-carnitina e di altri derivati acilati della carnitina - Google Patents

Nuova applicazione terapeutica della carnitina della acetil-carnitina e di altri derivati acilati della carnitina

Info

Publication number: IT1104165B
Authority: IT; Italy
Prior art keywords: carnitine; compsn; hyperlipaemia; hypercholesterolaemia; racemate
Prior art date: 1978-02-03

Application number

IT4790078A

Other languages

English (en)

Other versions

IT7847900A0 (it

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-02-03

Filing date

1978-02-03

Publication date

1985-10-21

1978-02-03 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1978-02-03 Publication of IT7847900A0 publication Critical patent/IT7847900A0/it

1978-02-03 Priority to IT4790078A priority Critical patent/IT1104165B/it

1979-01-31 Priority to DE2903558A priority patent/DE2903558C2/de

1979-01-31 Priority to DE19792903579 priority patent/DE2903579A1/de

1979-02-02 Priority to ZA79449A priority patent/ZA79449B/xx

1979-02-02 Priority to GB7903649A priority patent/GB2013495A/en

1979-02-02 Priority to NL7900871A priority patent/NL7900871A/xx

1979-02-02 Priority to BE193251A priority patent/BE873912A/xx

1979-02-02 Priority to GB7903650A priority patent/GB2013496B/en

1979-02-02 Priority to CA000320784A priority patent/CA1136551A/en

1979-02-02 Priority to ZA79450A priority patent/ZA79450B/xx

1979-02-02 Priority to CH106179A priority patent/CH640413A5/it

1979-02-02 Priority to BE193254A priority patent/BE873915A/xx

1979-02-02 Priority to CH106279A priority patent/CH640414A5/it

1979-02-02 Priority to NL7900872A priority patent/NL7900872A/xx

1979-02-03 Priority to JP1171779A priority patent/JPS54113442A/ja

1979-02-03 Priority to JP1171679A priority patent/JPS54113409A/ja

1979-10-10 Priority to US06/083,418 priority patent/US4255449A/en

1980-07-02 Priority to US06/165,351 priority patent/US4268524A/en

1985-10-21 Application granted granted Critical

1985-10-21 Publication of IT1104165B publication Critical patent/IT1104165B/it

Links

PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
208000035150 Hypercholesterolemia Diseases 0.000 title 1
208000031226 Hyperlipidaemia Diseases 0.000 title 1
229960004203 carnitine Drugs 0.000 title 1
230000007547 defect Effects 0.000 title 1
230000037356 lipid metabolism Effects 0.000 title 1
230000003287 optical effect Effects 0.000 title 1
PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
PHIQHXFUZVPYII-LURJTMIESA-N (S)-carnitine Chemical compound C[N+](C)(C)C[C@@H](O)CC([O-])=O PHIQHXFUZVPYII-LURJTMIESA-N 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
PHIQHXFUZVPYII-UHFFFAOYSA-N carnitine Chemical compound C[N+](C)(C)CC(O)CC([O-])=O PHIQHXFUZVPYII-UHFFFAOYSA-N 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
230000004060 metabolic process Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Emergency Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IT4790078A 1978-02-03 1978-02-03 Nuova applicazione terapeutica della carnitina della acetil-carnitina e di altri derivati acilati della carnitina IT1104165B (it)

Priority Applications (18)

Application Number	Priority Date	Filing Date	Title
IT4790078A IT1104165B (it)	1978-02-03	1978-02-03	Nuova applicazione terapeutica della carnitina della acetil-carnitina e di altri derivati acilati della carnitina
DE2903558A DE2903558C2 (de)	1978-02-03	1979-01-31	Verwendung von L-Carnitin
DE19792903579 DE2903579A1 (de)	1978-02-03	1979-01-31	Verwendung von acetylcarnitin und anderen acylderivaten des carnitins zur behandlung der hyperlipoproteinaemie und hyperlimpidaemie sowie arzneimittel
CA000320784A CA1136551A (en)	1978-02-03	1979-02-02	Composition containing acetyl carnitine and other acyl derivatives of carnitine for treating hyperlipoproteinaemias and hyperlipidaemias
CH106279A CH640414A5 (it)	1978-02-03	1979-02-02	Preparato terapeutico per il trattamento delle iperlipoproteinemie, dislipemie e malattie correlate.
NL7900871A NL7900871A (nl)	1978-02-03	1979-02-02	Werkwijze voor de therapeutische behandeling van hyperlipidemie en hyperlipiproteinemie.
BE193251A BE873912A (fr)	1978-02-03	1979-02-02	Compositions pharmaceutiques pour le traitement des hyperlipoidemies et des hyperlipoproteinemies
GB7903650A GB2013496B (en)	1978-02-03	1979-02-02	Treating hyperlipoproteinaemias and hyperlipidaemias
ZA79449A ZA79449B (en)	1978-02-03	1979-02-02	Therapeutic method for the treatment of hyperlipoproteinaemias and hyperlipodaemias
ZA79450A ZA79450B (en)	1978-02-03	1979-02-02	Use of acetyl carnitine and other acyl derivatives of carnitine for treating hyperlipoproteinaemias and hyperlipidaemias
CH106179A CH640413A5 (it)	1978-02-03	1979-02-02	Preparato farmaceutico per il trattamento di iperlipoproteinemie.
BE193254A BE873915A (fr)	1978-02-03	1979-02-02	Utilisation de l'acetyl carnitine et d'autres derives acyles de la carnitine dans le traitement des hyperlipoproteinemies et des hyperlipidemies
GB7903649A GB2013495A (en)	1978-02-03	1979-02-02	Therapeutic method for the treatment of hyperlipodaemias and hyperlipoproteinaemias
NL7900872A NL7900872A (nl)	1978-02-03	1979-02-02	Werkwijze voor het behandelen van hyperlipoproteinemie en hyperlipidemie.
JP1171779A JPS54113442A (en)	1978-02-03	1979-02-03	Treating agent of hyperlipoid disease
JP1171679A JPS54113409A (en)	1978-02-03	1979-02-03	Treating agent for hyperlipoid disease
US06/083,418 US4255449A (en)	1978-02-03	1979-10-10	Method of treating abnormal lipoprote in ratios
US06/165,351 US4268524A (en)	1978-02-03	1980-07-02	Method of treating abnormal lipoprotein ratios with acylcarnitine

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT4790078A IT1104165B (it)	1978-02-03	1978-02-03	Nuova applicazione terapeutica della carnitina della acetil-carnitina e di altri derivati acilati della carnitina

Publications (2)

Publication Number	Publication Date
IT7847900A0 IT7847900A0 (it)	1978-02-03
IT1104165B true IT1104165B (it)	1985-10-21

Family

ID=11263225

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT4790078A IT1104165B (it)	1978-02-03	1978-02-03	Nuova applicazione terapeutica della carnitina della acetil-carnitina e di altri derivati acilati della carnitina

Country Status (3)

Country	Link
BE (2)	BE873912A (it)
IT (1)	IT1104165B (it)
ZA (2)	ZA79449B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1156769B (it) *	1978-05-25	1987-02-04	Sigma Tau Ind Farmaceuti	Applicazione terapeutica della carnitina e di altri acil derivati della carnitina

1978
- 1978-02-03 IT IT4790078A patent/IT1104165B/it active
1979
- 1979-02-02 BE BE193251A patent/BE873912A/xx not_active IP Right Cessation
- 1979-02-02 ZA ZA79449A patent/ZA79449B/xx unknown
- 1979-02-02 BE BE193254A patent/BE873915A/xx not_active IP Right Cessation
- 1979-02-02 ZA ZA79450A patent/ZA79450B/xx unknown

Also Published As

Publication number	Publication date
ZA79450B (en)	1980-02-27
IT7847900A0 (it)	1978-02-03
BE873915A (fr)	1979-05-29
ZA79449B (en)	1980-02-27
BE873912A (fr)	1979-05-29

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Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19961216