IT1105463B - 1,2,4-triazine sostituite e composizioni che le contengono dotate di attivita'farmacologica anti-infiammatoria analgesica anti-piretica ipotensiva e sul sistema nervoso centrale - Google Patents

1,2,4-triazine sostituite e composizioni che le contengono dotate di attivita'farmacologica anti-infiammatoria analgesica anti-piretica ipotensiva e sul sistema nervoso centrale

Info

Publication number
IT1105463B
IT1105463B IT49404/78A IT4940478A IT1105463B IT 1105463 B IT1105463 B IT 1105463B IT 49404/78 A IT49404/78 A IT 49404/78A IT 4940478 A IT4940478 A IT 4940478A IT 1105463 B IT1105463 B IT 1105463B
Authority
IT
Italy
Prior art keywords
hypothensive
pyretic
triazines
analgesics
replaced
Prior art date
Application number
IT49404/78A
Other languages
English (en)
Italian (it)
Other versions
IT7849404A0 (it
Original Assignee
Diamond Shamrock Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/897,803 external-priority patent/US4157392A/en
Application filed by Diamond Shamrock Corp filed Critical Diamond Shamrock Corp
Publication of IT7849404A0 publication Critical patent/IT7849404A0/it
Application granted granted Critical
Publication of IT1105463B publication Critical patent/IT1105463B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT49404/78A 1977-05-17 1978-05-16 1,2,4-triazine sostituite e composizioni che le contengono dotate di attivita'farmacologica anti-infiammatoria analgesica anti-piretica ipotensiva e sul sistema nervoso centrale IT1105463B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79767677A 1977-05-17 1977-05-17
US05/897,803 US4157392A (en) 1977-05-17 1978-04-19 Pharmacologically active substituted 1,2,4-triazines

Publications (2)

Publication Number Publication Date
IT7849404A0 IT7849404A0 (it) 1978-05-16
IT1105463B true IT1105463B (it) 1985-11-04

Family

ID=27121911

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49404/78A IT1105463B (it) 1977-05-17 1978-05-16 1,2,4-triazine sostituite e composizioni che le contengono dotate di attivita'farmacologica anti-infiammatoria analgesica anti-piretica ipotensiva e sul sistema nervoso centrale

Country Status (8)

Country Link
JP (1) JPS5416491A (fr)
CA (1) CA1128507A (fr)
CH (1) CH633541A5 (fr)
DE (1) DE2821381A1 (fr)
FR (1) FR2391202A1 (fr)
GB (3) GB1604083A (fr)
IL (1) IL54728A (fr)
IT (1) IT1105463B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2485531A1 (fr) * 1980-06-25 1981-12-31 Fabre Sa Pierre Nouveaux n-oxydes de diaryl-5,6 as triazines 1-2-4, leur application a titre de medicaments et les compositions pharmaceutiques les contenant
US4616014A (en) * 1981-10-22 1986-10-07 Fujisawa Pharmaceutical Co., Ltd. Triazine derivatives, and pharmaceutical compositions comprising the same
US4513135A (en) * 1982-03-05 1985-04-23 Eli Lilly And Company Diaryl-pyrazine derivatives affecting GABA binding
US4581356A (en) * 1983-03-22 1986-04-08 Fujisawa Pharmaceutical Co., Ltd. Triazine derivatives, and pharmaceutical compositions comprising the same
DE3508665A1 (de) * 1985-03-12 1986-09-18 Hoechst Ag, 6230 Frankfurt Heterocyclische sulfide und ihre anwendung als immunmodulatoren
TWI316055B (fr) * 2001-04-26 2009-10-21 Nippon Shinyaku Co Ltd
ES2579949T3 (es) 2010-02-05 2016-08-17 Heptares Therapeutics Limited Derivados de 1,2,4-triazin-4-amina
FR2974099B1 (fr) * 2011-04-14 2013-04-19 Michelin Soc Tech Composition de caoutchouc comprenant un derive de la 1,2,4-triazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2343478A1 (fr) * 1976-03-10 1977-10-07 Lilly Co Eli Nouvelles 5,6-diaryl-1,2,4-triazines et leur utilisation comme agents anti-inflammatoires locaux
FR2368278A1 (fr) * 1976-10-25 1978-05-19 Fabre Sa Pierre Nouveaux medicaments antalgiques contenant des triazines 1-2-4

Also Published As

Publication number Publication date
JPS5416491A (en) 1979-02-07
FR2391202B1 (fr) 1982-04-02
DE2821381A1 (de) 1978-11-30
IL54728A (en) 1983-06-15
IT7849404A0 (it) 1978-05-16
IL54728A0 (en) 1978-07-31
FR2391202A1 (fr) 1978-12-15
GB1604085A (en) 1981-12-02
CH633541A5 (en) 1982-12-15
GB1604084A (en) 1981-12-02
CA1128507A (fr) 1982-07-27
GB1604083A (en) 1981-12-02

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